DYES AND PIGMENTS
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2026
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IF 3.9
Daoxin Wu,Shuyao Li,Jingkun Sun,Yang Qiu,Zhaoyang Wu,Wenzhao Liu
A novel ZIF-8/carboxylated polyurethane 3D photonic crystal sensor is developed for putrescine and cadaverine detection. • Dual sensing mechanism: ZIF-8 enables size-selective adsorption and refractive index modulation, while PU provides carboxyl-amine acid-base swelling. • The optimal sensor (n BDO :n DMBA = 3:7) achieves a low detection limit of 0.86 ppm for putrescine and high selectivity over common VOCs. • Synergistic signal amplification yields a maximum reflection peak shift of 27.02 nm at 100 ppm. Rapid on-site detection of biogenic amines (e.g., putrescine and cadaverine) is critical for food freshness monitoring. Herein, we report a three-dimensional photonic crystal (3DPC) sensor composed of ZIF-8 nanoparticles and carboxyl-functionalized polyurethane (PU). The PU matrix, with tunable carboxyl content via DMBA/BDO ratio, enables acid-base induced swelling upon exposure to amine vapors, while ZIF-8 provides size-selective enrichment and refractive index modulation. The sensor with an optimal n BDO :n DMBA molar ratio of 3:7 exhibits a low detection limit of 0.86 ppm for putrescine, a sensitivity of 0.2384 nm/ppm, and excellent selectivity over common VOCs. The synergistic dual-mechanism (swelling + refractive index change) yields a maximum reflection peak shift of 27.02 nm at 100 ppm. Moreover, the sensor shows moderate response time (2.5 min) and good long-term stability (35 days). This work provides a new strategy for integrating MOF adsorption and polymer swelling into a visual sensing platform for biogenic amines.
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BIOMATERIALS
·
2026
·
IF 13.6
Canyi Chen,Qinqing Tang,Qinyao Xu,Dehui Feng,Qiang Luo,Bin Xu,Hanyuan Zhang,Tingting Zhao,Weijun Fang
Targeted autophagy regulation holds great promise for antitumor therapy, whereas conventional single-modal autophagy interventions easily induce compensatory escape of tumor cells and fail to transform protective autophagy into a lethal phenotype. In this study, a near-infrared (NIR)-responsive polypyrrole/zeolitic imidazolate framework-8 (PPy/ZIF-8) nanoparticle was successfully fabricated. This nanoplatform enables synergistic and precise regulation of autophagic flux, which amplifies upstream autophagy activation and blocks downstream autophagic pathways simultaneously. The incorporation of PPy endows the nanoparticle with excellent near-infrared absorption capability and photothermal effects. It boosts interfacial electron transfer and optimizes electron-hole separation, further enabling the nanoparticles to possess ROS generation ability. Under 808 nm laser irradiation, the generated ROS and zinc ions induce mitochondrial damage to amplify upstream autophagic signals, whereas the photothermal effect impairs lysosomal function and blocks the downstream degradation of autophagosomes. This dual regulatory strategy causes pathological accumulation of autophagosomes and ultimately triggers autophagic cell death in tumor cells. This work validates the feasibility of integrated autophagy regulation and provides a facile and versatile strategy for the design of advanced multimodal antitumor nanotherapeutics.
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ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Mingdong Sun,Shibo Xi,Siyu Zhu,Yu Zhou,Changping Li,Biao Meng,Jiao Wei,Xiao Chi,Xiaojiang Yu,Yujie Cao,Yizhong Huang,Xiaoling Liu,Jun Wang
N-doped carbon-supported single-atom metal sites (Me−N−C) have emerged as promising candidates for electrochemical CO 2 reduction reaction (CO 2 RR) under industrial current densities. However, rationalizing their local coordination environment remains challenging. Herein, a feasible strategy is demonstrated for constructing robust Ni─N─C centers by designing a new family of single-crystalline ionic ZIF-8 materials with atomically defined ionic liquid (IL) cations inside the microchannels. The ─COOH tethered ionic ZIF-8 directed the formation of atomically dispersed Ni─N 4 sites with an elongated Ni─N bond of 1.94 Å. The resulting Ni─N─C catalyst effectively catalyzed the electrochemical CO 2 reduction to CO, delivering a partial current density of 679 mA cm −2 with a Faradic efficiency of 97% and achieving a maximum turnover frequency of 106197 h −1 . The extended Ni─N bond enables the slightly reduced valence state of the Ni site, optimizing the affinity toward CO 2 and intermediate, and thus lowering the energy barrier in the rate-determining * CO 2 → * COOH step.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Shulan Chen,Jiang Huang,Wenyue Chen,Hongwen Wu,Hongliang Tan
Hybridization gating reduces fluorophore ratio-control constraints. • Post-activation dye recruitment limits background from pre-integrated signal dyes. • Immunomagnetic enrichment provides target selectivity for ATP-based sensing. • Chitosan-modified hydrogel limits acid-induced background in portable readout. Rapid bacterial detection in dairy food safety monitoring requires portable platforms that combine analytical sensitivity with target selectivity. Here, we report a hybridization-gated zeolitic imidazolate framework-8 (ZIF-8) ratiometric nanoprobe, designated RSZ, for portable detection of Staphylococcus aureus ( S. aureus ) through adenosine triphosphate (ATP)-triggered DNA duplex signaling. The RSZ probe adopts a dual-zone architecture with Ru(bpy) 3 2+ and ssDNA1 embedded within the ZIF-8 particle interior and ssDNA2 adsorbed on the exterior surface. This architecture separates the stable reference channel from the formation of the responsive fluorescence channel, thereby reducing dependence on precise dual-fluorophore loading and limiting background associated with a pre-integrated responsive fluorophore. Upon ATP-induced framework disruption, ssDNA1 becomes accessible for hybridization with ssDNA2, and the resulting duplex recruits SYBR Green I from solution to generate the responsive fluorescence channel relative to the stable Ru(bpy) 3 2+ reference. To enable field-deployable detection, the nanoprobe is embedded in a chitosan-modified agarose hydrogel in which chitosan maintains a near-neutral microenvironment and limits acid-induced nonspecific activation. Fe 3 O 4 nanoparticles conjugated with porcine immunoglobulin G (Fe 3 O 4 -pIgG) are integrated upstream to selectively capture S. aureus via protein A-pIgG recognition, followed by smartphone red-green-blue analysis without specialized instrumentation. The integrated platform achieves a detection limit of 6 CFU/mL and recoveries of 98.8–101.7% in spiked milk. Therefore, this study demonstrates a hybridization-gated strategy for translating stimulus-induced ZIF-8 disruption into controlled ratiometric signal generation for portable bacterial sensing in food analysis. Download: Download high-res image (106KB) Download: Download full-size image
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SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Chang Liu,Xing Luo,Guowang Shen,Fengfeng Gao,Xueli Huang,Xueying Wang,Qinglong Luo
Ag NPs@Cu-ZIF-8: ZIF-8 modified by partial Cu 2+ doping and Ag NPs loading. • The electrode maintains 128.2 mg・g −1 capacity after 10 Br − cycles. • At optimal conditions, the electrode achieves 147.2 mg·g −1 maximum Br − capacity. • DFT proves Cu 2+ -Ag modification enhances Br − adsorption. Bromide ions (Br − ) are finite and non-renewable strategic resources, and their highly selective recovery is of great significance for the sustainable utilization of brine resources and ecological environmental protection. To address the shortcomings of conventional adsorbents such as poor electrical conductivity and insufficient active sites, an Ag NPs@Cu-ZIF-8 composite was successfully constructed via a synergistic modification strategy involving copper framework doping and silver nanoparticle loading in this study. The composite not only retains the inherent porous structural advantages of ZIF-8 but also effectively overcomes its poor electrical conductivity. Systematic material characterizations combined with density functional theory (DFT) calculations were employed to reveal the microscopic adsorption mechanism of the composite toward Br − in aqueous solution. The results demonstrate that the introduction of silver nanoparticles significantly enhances the electrical conductivity of the material and provides abundant active adsorption sites for Br − capture. Electrochemical test results reveal that the Ag NPs@Cu-ZIF-8 membrane electrode achieves a maximum bromide adsorption capacity of 147.2 mg·g −1 under optimal experimental conditions. The adsorbed bromide can be converted into elemental bromine through extraction, realizing efficient resource recovery. Cycling experiments indicate that the adsorption capacity only drops from 139.7 mg·g −1 to 93.5 mg·g −1 after ten adsorption-desorption cycles under conventional conditions, which reflects outstanding cycling stability. This material presents prominent advantages for the green and efficient recovery of bromine resources. Download: Download high-res image (104KB) Download: Download full-size image
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Catalysis Science & Technology
·
2025
·
IF 4.2
Bin Guan,Junyan Chen,Lei Zhu,Zhongqi Zhuang,Xuehan Hu,Chenyu Zhu,Sikai Zhao,Kaiyou Shu,Hongtao Dang,Junjie Gao,Luyang Zhang,Tiankui Zhu,Wenbo Zeng,Minfan Qian,Zhangtong Li,Yang Lu,Shuai Chen,Zhen Huang
Herein, Co–Zn bimetallic center-modulated ZIF-67@ZIF-8 composites were prepared by ultrasonic synthesis, and the effects of the metal ratio on the photothermal coupling catalytic CO2 reduction performance and product selectivity were systematically investigated. The experiments showed that catalysts with higher Zn content (e.g., Co0.1Zn0.9) exhibited higher CH4 selectivity (29.32%), while the high Co ratio (e.g., Co0.9Zn0.1) significantly enhanced the CO generation rate (3.13 μmol g−1 h−1). Characterization by N2 adsorption, XRD, XPS, UV-vis DRS, and in situ DRIFTS revealed that the metal ratio affected the CO2 adsorption and electron transport efficiency by modulating the catalyst specific surface area (1213 → 555 m2 g−1), the band gap width (3.53 → 3.39 eV), and the distribution of the surface-active sites. The DFT calculations further revealed the synergistic effect of Co/Zn: high Zn content lowers the *CHO generation barrier (3.45 eV) and promotes the CH4 pathway, while the Co center enhances CO2 activation. This study provides a theoretical and experimental basis for the optimization of CO2 reduction product selectivity through precise regulation of metal centers.
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 2
·121676
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IF 7.5
Xiaonan Hao,Ying Xue,Yue Wu,Shulin Sun
The inherent hydrophobicity of polyvinylidene fluoride (PVDF) separation membranes severely limits their flux and anti-fouling performance, and traditional membrane materials struggle to simultaneously achieve efficient separation and degradation of pollutants. This study innovatively proposes a synergistic modification strategy combining Chlorinated 1-butyl-3-vinylimidazole (IL) grafting with amino-functionalized zeolitic imidazolate framework-8 (NH 2 -ZIF-8) doping. This approach constructs a multifunctional composite membrane integrating efficient separation, adsorption, and piezo-photocatalytic degradation. The prepared PVDF-g-IL/NH 2 -ZIF-8 membrane demonstrates outstanding overall performance. Under combined ultrasound and ultraviolet excitation, it achieves a methylene blue degradation efficiency of 80.5 %, showcasing its capability for in-situ pollutant degradation during the separation process. Furthermore, the membrane exhibits a pure water flux as high as 685.6 L m −2 h −1 , which is approximately seven times that of the pristine PVDF membrane. It also maintains dye rejection rates exceeding 93 % for various dyes, and possesses a high adsorption capacity (>7.0 mg/g) along with excellent cycling stability due to the flux recovery rate above 80 %. This study provides new insights for developing water treatment membranes combined efficient separation with in situ degradation functionality.
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ANALYTICA CHIMICA ACTA
·
2026
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IF 6.1
Hongyu Ning,Yilei Fan,Haodong Wang,Huijun Liu,Zhongping Huang,Haixing Wang,Xing Ke,Yu Xu
Background The global increase in cannabis use has created a strong demand for reliable and efficient detection methods. Traditional urine-based assays are widely used and standardized, but suffer from complex hydrolysis requirements, long detection windows, and an inability to monitor recent use. In contrast, oral fluid testing enables non-invasive, real-time detection of parent cannabinoids, but is limited by low sample volume, matrix interference, and insufficient sensitivity in common rapid tests. It is clear that a sample preparation and detection approach is needed that is robust, highly sensitive, streamlined, and compatible with high-throughput confirmatory analysis such as LC-MS/MS. Results In this study, a magnetic solid-phase extraction (MSPE) method was developed using a novel magnetic metal–organic framework composite, Fe 3 O 4 @poly(GMA/DVB-ZIF-8), for the efficient extraction of four cannabinoids from urine and oral fluid. The sorbent uses multiple interactions—including hydrophobic, π–π, electrostatic, and Zn–O coordination—to achieve high analyte recovery (exceeding 85%). Coupled with UHPLC-MS/MS analysis, the method demonstrates wide linearity (0.05–25 ng/mL, r 2 > 0.9945), low detection limits (as low as 0.017 ng/mL), and good repeatability (RSDs <13.8%). Comparative evaluation with conventional liquid–liquid extraction showed minimal deviation (relative percent difference <6.0%), confirming high trueness and reliability for cannabinoid monitoring in biological samples. Significance This MSPE approach provides a simple, efficient and high-throughput sample preparation method for reliable and rapid forensic analysis of cannabinoids in complex biological samples.
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Materials Today Chemistry
·
2026
·
IF 7.4
Shuoye Yang,Jinpeng Wang,Qianqian Cheng,Huajian Yuan,Lin Ju,Xin Wang,Suxi Liu,Ruolan Song,Ning Li,Lu Zhang,Peng Li
Chemotherapy drugs are often associated with toxic side effects and low bioavailability, while solid tumors like breast cancer frequently exhibit multidrug resistance, which limits the clinical efficacy of chemotherapy and other monotherapies. To address these challenges, there is a need for the development of efficient delivery systems capable of transporting various therapeutic agents while introducing novel programmed death mechanisms to achieve synergistic antitumor effects. In this study, zeolite imidazole-8 (ZIF-8) was utilized as a core carrier to load doxorubicin (DOX) and photothermal agent CuS, and further coated by folic acid (FA)-functionalized red blood cell membranes (RBCM) to fabricate the FRCZD delivery system. This system possessed the capacity to target breast cancer MCF-7 cells and their drug-resistant strain, MCF-7/ADR cells. Notably, DOX and CuS were rapidly released in response to both the tumor microenvironment (TME) and near-infrared radiation (NIR). Under light stimulation, CuS induced photothermal therapy (PTT), which further enhanced localized drug accumulation while catalyzing H 2 O 2 to produce toxic hydroxyl radicals (⋅OH) that triggered chemodynamic therapy (CDT). Moreover, excessive intake of Cu 2+ led to mitochondrial metabolic dysfunctions that ultimately initiated cuproptosis. The results demonstrated that FRCZD combined with NIR accelerated cell apoptosis while interfering with cell cycle distribution, consequently inhibiting tumor cell proliferation and migration. In vivo experiment results further corroborated that FRCZD + NIR significantly inhibited tumor growth more effectively than other experimental groups while exhibiting favorable biological safety profiles. Overall, the integrated platform FRCZD could substantially enhance treatment outcomes by inducing cuproptosis in conjunction with chemotherapy, PTT, and CDT approaches, thus holding promise for advancing therapies against drug-resistant tumors.
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ACS Omega
·
2026
·
IF 5.2
Tao Yang,Tao Wang,Tao Shen,Mingrong Dong,Jinkun Liu,Ming Ni,Yan Zhu
Targeting tumor-specific characteristics of acidic microenvironment, elevated H2O2 levels, and thermosensitivity, this study proposed and developed a copper-doped ZIF-8 nanoplatform coloaded with indocyanine green (ICG) and doxorubicin hydrochloride (DOX), designated as Cu-ZIF-8@ICG&DOX (CZID), to establish a multimodal therapeutic system integrating chemodynamic therapy, photothermal therapy, and chemotherapy. Results showed that the 25% copper doping level optimized the structure, achieving 7.46% actual doping content while limiting the average nanoparticle size to 99.6 nm. Dual loading of ICG and DOX induced morphological transition to spherical core–shell architectures, as confirmed by zeta potential reversal, with maximum drug loading capacities of 23.01 μg/mg for ICG and 122.43 μg/mg for DOX. The ZIF-8 framework exhibited pH-responsive degradation under acidic conditions. Released Cu2+ ions mediated continuous hydroxyl radical generation through glutathione-depletion redox cycling, confirming chemodynamic efficacy. Under 808 nm laser irradiation, ICG enabled enhanced photothermal conversion, showing concentration- and power-dependent temperature elevation. Cellular assays revealed efficient CZID internalization by MCF-7 cells, generating significantly higher intracellular reactive oxygen species levels under irradiation and more intense dead cell staining compared to CZI and CZD groups. Such an enhancement was attributed to photothermally accelerated ZIF-8 degradation, promoting Cu2+ ions and DOX release, thereby strengthening chemodynamic–chemotherapy synergy. At the working concentration of 50 μg/mL, CZID induced 95.36% apoptosis in MCF-7 cells while maintaining over 70% viability in MCF-10A normal cells, validating its precise antitumor potential.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2026
·
IF 6.7
Tianlong Huang,Zhen Mu,Yuanxiang Zhang,Maosheng Cui,Xiaoxiao Wang,Yang Zhang,Lingxiu Chen,Xiaolan Xue
Magnesium-metal organic batteries (MMOBs) are promising candidates for large-scale energy storage due to their high theoretical capacity, abundant resource, and cost-effectiveness. However, the high solubility of organic molecules and the commonly used thick glass fiber separators with poor mechanical strength and high cost hinder their further development. Herein, we report a ZIF-8/Carbon composite-modified polypropylene/polyethylene/polypropylene (ZIF-8/C@PEP) separator to overcome these limitations. This ZIF-8/C@PEP separator was fabricated by uniformly coating a mixture of ZIF-8 and carbon black onto a PEP separator via a doctor-blade method. The porous structure of ZIF-8 acts as a molecular sieve, effectively blocking the diffusion of soluble anthraquinone (AQ) species toward the anode while allowing facile Mg 2+ ion transport. Meanwhile, the carbon black enhances the separator’s compactness and provides additional physical confinement and adsorption sites for soluble molecules. Benefiting from these synergistic effects, by implementing the ZIF-8/C@PEP separator, Mg||Mg cells exhibit stabilized Mg plating/stripping behavior with reduced overpotential, while Mg||AQ full cells deliver good cyclability, maintaining a capacity of 104.8 mAh g −1 after 100 cycles at 0.05 A g −1 with a Coulombic efficiency of 98%. The results demonstrate that separator modification represents a promising strategy for enhancing the performance of MMOBs.
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NANOTECHNOLOGY
·
2022
·Vol. 34
·期 8
·085401
·
IF 3.953
Hongna Jia,Yao Wang,Shuya Zhao,Haipeng Wang,Na Ju,Xinyue Zhang,Hong Li,Zejun Sun,Hong-bin Sun
Carbon materials derived from metal-organic frameworks have attracted increasing attention as anodes for energy storage. In this study, Fe, Ni-doped ZIF-8 is carbonized at high temperature to obtain bimetallic Fe and Ni modified tension -relaxed carbon (FeNi@trC). Fe and Ni have opposite structural modification effects when the metal ions are doped into the ZIF-8 dodecahedron. The obtained carbon material maintains the regular dodecahedron morphology, which means the relaxation of tension and strong thermal stability during annealing. Moreover, the presence of nickel enhances the carbonization degree and electrochemical stability of FeNi@trC, while the calcination of the tensive ZIF-8 precursor offers more defect sites. The discharge capacities of FeNi@trC materials are stable at 182.9 mAh·g−1 and 567.9 mAh·g−1 for sodium-ion batterie (SIB) and lithium-ion batterie (LIB) at 0.05 A·g−1. Compared with the current density of 0.05 A·g−1, the discharge capacity of SIB and LIB attenuates by 29.4% and 55.9% at 1 A·g−1, respectively, and the FeNi@trC shows good performance stability in the following cycles.
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危险品化学品经营许可证（带存储）