JOURNAL OF NANOBIOTECHNOLOGY
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2025
·Vol. 23
·期 1
·1-21
·
IF 12.6
Zhang Fenglan,Wang Tianyi,Wang Wenqiao,Lv Yaqian,Qu Yingshan,Liu Danping,Sun Xiaoyue,Kong Xiaoying,Wang Changyuan,Shi Jinsheng
As an important component of sunscreen products for sensitive skin, the potential damage mechanism of ZnO nanoparticles on skin surface with barrier structure or function defect caused by Cutibacterium acnes (C. acnes) has not been elucidated, which poses a serious challenge for reasonable selection of sunscreen products for acne-infected skin. In this work, we demonstrated for the first time that C. acnes induced significant changes in the membrane permeability and intracellular pH of fibroblasts through lipase up-regulation and lipid peroxidation, promoting endocytosis and ionization of ZnO NPs. High amounts of Zn2 + further delayed acne wound healing and aggravated scar hyperplasia by intervening matrix metalloproteinase-9 (MMP-9) and TGF-β1/Smad pathway. MMP9 was confirmed to be the key target of ZnO in delaying acne wound healing by the wound regulatory effects of MMP9 agonist and MMP9 inhibitor. In summary, this work clarified the interaction mechanism between ZnO NPs and acne skins, providing guideline for the application of physical sunscreens for special skins.Graphical abstract
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Frontiers in Physiology
·
2025
·
IF 3.4
Long Liu,Yangdi Li,Hua Yang,Fan Wang,Qiong Huang
Odorant-binding proteins (OBPs) are important for insects to discriminate, bind and transport odorants, such as pheromones and host plant volatiles. Herein, the Minus-C OBP (CbuqOBP1) was characterized from Cyrtotrachelus buqueti , one of the most important pests in bamboo plantations. CbuqOBP1 showed significantly higher transcription levels in the adult stage and was most highly expressed in the head of both sexes, the thorax and antenna of the male, indicating that it plays important roles in chemosensory behavior of adults and may also function in other biological processes. Fluorescence competitive binding assays showed that CbuqOBP1 displayed broad binding capabilities and strong affinities to phenol ( K i = 10.49 μM) and benzothiazole ( K i = 11.11 μM) among 8 C. buqueti volatiles. CbuqOBP1 also showed high binding affinity to the main volatile of the host plant Neosinocalamus affinis (linalool, K i = 13.41 μM). The docking results indicated that hydrophobic interactions were the prevailing forces between CbuqOBP1 with these three ligands. Additionally, several amino acid residues were significantly overlapped and contributed to the interactions with the ligands. The combined results suggest that CbuqOBP1 may play dual roles in binding volatile compounds from the host plant and the same species and will be helpful to developing new pest-control strategies.
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JOURNAL OF POWER SOURCES
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2025
·
IF 7.9
Yulei Ren,Xuming Zhang,Hao Song,Chaoran Pi,Jianping Li,Xingju Liu,Chan Lin,Pengcheng Wei,Zhuo Li,Paul K. Chu
The advancement of non-precious electrocatalysts with high efficiency is crucial for the industrial implementation of the hydrogen evolution reaction (HER). In non-acidic environments, the dissociation of water and interactions between hydrogen and the catalyst are pivotal. This research presents a novel hybrid electrocatalyst, comprising a molybdenum oxycarbide and carbide heterojunction integrated onto carbon cloth (MoOC-Mo 2 C/C), which is fabricated through in situ interface engineering. The MoOC-Mo 2 C catalyst demonstrates exceptional electrical conductivity and remarkable HER performance across a wide pH range, particularly in alkaline conditions, as exemplified by Tafel slope of 38 mV dec − 1 , an ultralow overpotential of 45 mV at a current density of 10 mA cm −2 , and notable long-term stability. Both experimental findings and theoretical analyses suggest that the incorporation of oxygen into the carbide structure enhances water adsorption and lowers the energy barrier for water dissociation. Furthermore, the distinct work functions of MoOC and Mo 2 C facilitate effective electron transfer from MoOC to Mo 2 C, optimizing the energy of hydrogen adsorption and significantly enhancing the activity and kinetics of alkaline HER. Our results underscore the promising potential of this highly efficient non-precious electrocatalyst, which exhibits a pronounced affinity for water molecules, in facilitating hydrogen evolution in alkaline media.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yapeng Li,Qinghong Pan,Huiting Shi,Youyou Du,Ailing Yang,Da-Peng Yang
The quantitative determination of cholesterol in foods, drugs, and biological fluids holds significant importance due to its potential health risks. Herein, a self-powered photoelectrochemical (PEC) sensor was developed for cholesterol detection. The photoelectrochemical system was constructed by modifying fluorine-doped tin oxide (FTO) electrodes with ZnO/C (serving as the photoanode) and iron-modified CuBi 2 O 4 (denoted as CBFO, functioning as the photocathode) through a controlled deposition process. To enhance detection selectivity, molecularly imprinted polymers (MIPs) were electrodeposited on the photocathode surface. The optimized sensor exhibited a linear detection range of 1–1000 nmol L −1 and a detection limit of 0.26 nmol L −1 (S/N = 3). Practical application of the sensor for cholesterol detection in milk samples demonstrated satisfactory recovery rates (98.6 %–107 %) with relative standard deviations (RSD) ranging from 2.38 % to 4.25 %. These results underscore the potential of this self-powered PEC sensor as a robust platform for rapid and accurate cholesterol determination in food products, pharmaceuticals, and environmental samples.
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JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2011
·Vol. 11
·期 12
·10320-10323
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IF 1.352
Yan Shancheng,Xu Xin,Sheng Yun,Sun Huabin,Wu Jiansheng,Tang Lihua
A novel disposable biosensor is developed based on gold nanoparticles modified CdS nanorod arrays. The ordered CdS nanorod arrays firstly have been synthesized by a simple hydrothermal method. Then, the CdS nanorod arrays are modified by gold nanoparticles, which are directly fabricated
into an electrode for detection of cytochrome c (Cyc) in solution without any pretreatment. The modified CdS nanorod arrays biosensor with the immense surface area and high electrical conductivity shows a good sensitivity and linear range. This method may be used to construct other electrochemical
biosensors using aligned nanorod/nanowire films.
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Materials Today Communications
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2022
·
IF 3.662
Tao Wen,Yang Feng,Yuqiang Bi,Liang Xu,Changping Guo
In this work, nano Co 3 O 4 /C composite catalyst was in-situ synthesized on sponge by high-temperature calcination , and as a catalyst for the thermal decomposition of AP. SEM, EDS , XRD and BET analyses showed that the prepared samples were evenly distributed and nano-sized Co 3 O 4 /C composites. Moreover, the catalytic effect of the nanocomposite catalyst on the thermal decomposition of AP was studied by DSC and TG. The influence of different factors on the thermal decomposition performance of AP were studied. The results indicated that when the Co 3 O 4 /C composite catalyst content was 5 wt%, the high-temperature decomposition (HTD) peak of AP was reduced from 430.1 to 319.0 ℃ and the activation energy from 237.5 down to 81.1 kJ mol −1 . In addition, the possible catalytic mechanism was also briefly discussed. Therefore, all the results indicated that the 3D porous nano Co 3 O 4 /C composite catalyst demonstrated excellent catalytic performance for the thermal decomposition of AP.
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GREEN CHEMISTRY
·
2019
·Vol. 21
·期 8
·2129-2137
·
IF 9.405
Di Liu,Ping Yang,Hao Zhang,Minjie Liu,Wenfei Zhang,Dongmei Xu,Jun Gao
A non-noble heterogeneous catalyst – a Co, N and C composite encapsulated carbon nanotube grown in situ on the surface of activated carbon (Co–N–C/CNT@AC) – was fabricated via the pyrolysis–reduction process. Co–N–C/CNT@AC catalyzed the reductive coupling of structurally diverse nitroarenes and alcohols to imines and secondary amines under exogenous base- and solvent-free conditions. BET, TEM, SEM, XRD and XPS characterization showed that the exceptional catalytic property of Co–N–C/CNT@AC could be explained by its nanostructure, Co–N and basic N species. Our protocol had advantages of low cost, environment-friendliness, and good applicability. Furthermore, a reaction route of nitroarenes, amines and alcohols as the starting materials was proposed to improve the atom economy of the reductive coupling of nitroarenes with alcohols.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2023
·
IF 8.6
Chaogang Ban,Yang Wang,Jiangping Ma,Yajie Feng,Junjie Ding,Youyu Duan,Xue Liu,Bin Zhang,Jinjing Tang,Xiaoping Tao,Liyong Gan,Shuangshuang Tan,Xiaoyuan Zhou
Rational fabricating advanced photocatalysts to recycle CO 2 into solar fuel is one of the most promising approaches to simultaneously address energy shortages and global warming. TiO 2 has been widely used in photocatalytic CO 2 reduction due to its abundant reserves, non-toxicity and harmlessness etc. However, it remains significantly challenging for practical applications due to the fast electron-hole recombination. Herein, we design a direct TiO 2 based Z-Scheme heterojunction by self-assembly of C-doped TiO 2 nanoparticles on 3D hierarchical petal of flower-like β-Bi 2 O 3 (C-TiO 2 /β-Bi 2 O 3 ). In situ electron paramagnetic resonance tests, in situ X-ray photoelectron spectroscopy and theoretical calculations reveal that electrons are transferred from β-Bi 2 O 3 to C-TiO 2 due to the formation of Z-Scheme heterojunction, which greatly accelerates the separation of photogenerated carriers to promote efficient CO 2 photoreduction. Ultimately, the optimal heterojunction shows significantly enhanced photocatalytic activity for CO 2 reduction to CO (31.07 μmol g –1 h −1 ) compared to the pure TiO 2 (3.28 μmol g –1 h −1 ) without using any photosensitizers and sacrificial agents. This work provides a unique insight to design direct Z-Scheme heterojunctions and delivers a promising photocatalyst for overcoming global warming and energy-supply issues.
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ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Liying Zhao,Xiaoxiao Song,Xueliang Ouyang,Jiahong Zhou,Jinping Li,Dawei Deng
Bioinspired strategies have recently emerged as novel approaches for designing a functionalized nanovector with enhanced tumor targeting and therapeutic efficacy. Herein, a virus-like Fe3O4/Au@C nanovector is described for programmable drug delivery via hierarchical targeting. Specifically, the virus-like Fe3O4/Au@C nanovector is synthesized via a simple hydrothermal process, and then the spiky surface of which is camouflaged via doxorubicin (DOX)-conjugated polyethylene glycol (PEG), constructing an innovative virus-like core/spherical shell biomimetic nanomedicine (Fe3O4/Au@C-DOX-PEG), which is conducive to improve bioavailability and reduce adverse effects. After systemic administration, the as-prepared nanomedicine is capable of facilitating effective tumor accumulation and deep tumor penetration with the assistance of an external magnetic field and endogenous pH stimuli. Simultaneously, in response to the acidic tumor microenvironment, Fe3O4/Au@C-DOX nanocomposites are released and exhibit excellent performance in cellular internalization through a virus-mimetic rough surface. Furthermore, the in vivo experiments identify that the unique nanomedicine is bestowed with an effective targeting tumor, prominent antitumor efficacy, and reduced systemic toxicity. Such a bioinspired hierarchical targeting nanoplatform holds promising potential for enhanced chemotherapeutic intracellular delivery and tumor theranostics.
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Nanoscale
·
2020
·Vol. 12
·期 19
·10771-10780
·
IF 6.895
Guangqi Hu,Xiaokai Xu,Bingfu Lei,Jianle Zhuang,Xuejie Zhang,Haoran Zhang,Chaofan Hu,Xiaotang Liu,Yingji He,Yingliang Liu
C-Dots and composites based on them face the challenges of poor stability, especially under photo-radiation, and low solid-state photoluminescence quantum yields (PLQYs), which hinder their application in optical devices. Herein, a novel 2-dimensional hybrid material of polysiloxane embedded with Si-doped carbon dots (P-E-Si-CDs) was synthesized by a self-assembly approach, and the hybrid composite exhibited broadband blue-green fluorescence emission, outstanding photostability, high thermal stability, and a high PLQY of 82.8%. Moreover, the dual fluorescent emissions were demonstrated the creation of two closed-loop fluorophores. Using the as-prepared hybrid fluorescent material, fabricated light-emitting diodes (LEDs) based on UV and blue-emitting LED chips present safe warm white light emission and adjustable white emission with a high color rendering index of up to 91, respectively. This work provides a novel strategy for the design and realization of Si-CD-based hybrid composites, thus promising their prospective use commercially in LED lighting.
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JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2022
·
IF 6.364
Xudong Wang,Ke Chen,Ziqian Li,Haoming Ding,Yujie Song,Shiyu Du,Zhifang Chai,Hui Gu,Qing Huang
Herein, a series of chalcogen-containing MAX phases, Hf 2 (Se x S 1−x )C, were successfully synthesized, whose lattice parameter change follows the Vegard’s law. The average coefficient of thermal expansion (CTE) can be continuously tuned from 7.59 μK −1 to 9.93 μK −1 when the occupancy rate x of Se changes from 0 to 1. The substitution of Se for S effectively soften the crystal structures that is reflected by long average M-A bond in Se-alloying Hf 2 (Se x S 1−x )C. However, the CTEs along a and c axes in all Hf 2 (Se x S 1−x )C MAX phases are almost same which may be find application in thermal barrier coating (TBC) that isotropic volume change is highly demanding.
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Progress in Natural Science-Materials International
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2018
·
IF 2.572
Datong Zhang,Zhengping Ding,Shuai Zhao,Ying Yang,Yiming Feng,Lei Xiao,Ran Ji,Libao Chen,Weifeng Wei
Li 2 MnSiO 4 -based cathode materials possess reasonable work potentials and high theoretical capacities, while the practical energy/power densities are constrained by their inferior kinetics of Li + diffusion. In this work, the Pmn2 1 -structure Li 2 Fe x Mn 1-x SiO 4 /C materials were synthesized via a solvothermal method and evaluated as Li-ion cathode materials, with notable morphological evolutions and tunable crystallographic habits observed after solvothermal process. The Li 2 Fe 0.33 Mn 0.67 SiO 4 /C material delivers an initial reversible capacity of 250.2 mAh g −1 at 0.1 C (~ 1.51 Li + insertion/extraction, 1 C = 166 mA g −1 ), excellent high-rate capability (52.2 mAh g −1 at 5 C), and good long-term cyclability (64.6% after 196 cycles at 2 C). The enhanced electrochemical properties are attributed to the boosted ion/electron transports induced by preferred morphological and structural characteristics of Li 2 Fe 0.33 Mn 0.67 SiO 4 /C.
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