Nanomedicine-Nanotechnology Biology and Medicine
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2026
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IF 4.3
Guiyin Li,Xiaohong Tan,Shuang Liang,Qiufei Yu,Yibin Yu,Xiangming Li,Zhide Zhou
s Quantitative detection of Golgi protein 73 (GP73), a promising biomarker for hepatocellular carcinoma (HCC), is crucial for early diagnosis. In this study, we developed a fluorescence aptasensor for sensitive and specific detection of GP73 based on fluorescence resonance energy transfer (FRET) between GP73 aptamer-functionalized nitrogen/sulfur co-doped graphene quantum dots (N, S-GQDs-GP73 Apt ) as the fluorescence donor and molybdenum disulfide@reduced graphene oxide (MoS 2 @RGO) as the fluorescence acceptor. In the absence of GP73, the fluorescence of N, S-GQDs-GP73 Apt was effectively quenched by MoS 2 @RGO. Upon introduction of GP73, specific binding between GP73 and its aptamer triggered dissociation of the donor-acceptor complex, disrupting FRET and restoring fluorescence. Under optimized conditions, the normalized fluorescence intensity showed a good linear relationship with GP73 concentration ranging from 0.0001 to 100.0 μg/mL, with a low detection limit of 0.019 ng/mL. The aptasensor's performance was further validated using human serum samples with relative error ranging of 0.76%–3.85% and no statistically significant difference via t -test compared with ELISA results, demonstrating its potential as a reliable and cost-effective platform for early HCC diagnosis. Download: Download high-res image (97KB) Download: Download full-size image
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Inorganic Chemistry Frontiers
·
2023
·Vol. 10
·期 17
·4993-5003
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IF 7
Yuanduo Qu,Siqi Liao,Liangyi Wu,Junkai Wang,Lianfeng Duan,Xia He,Fushen Lu
An integrated photocapacitor (IPC) is a light-driven self-charging capacitor, which can overcome the impact of solar energy fluctuations by converting the solar radiation to electrochemical energy and store it simultaneously. However, current IPCs suffer from incompatibility problems, device packing, serious carrier recombination, and long-range electron transmission path, which lead to low conversion efficiency and cycling performance. To address these issues, we propose a three-electrode quasi-solid-state IPC based on a charge-separated transition mechanism of PEDOT/RGO compatible electrode and BMIMBF4 ion gel electrolyte to accelerate carrier migration. The overall conversion efficiency of this IPC reached 5.8% and the energy storage efficiency could be maintained at 84.57%. Besides that, this bendable free-standing electrode can be applied in flexible and high-voltage IPCs as a reliable off-grid systems to supply next-generation electronics.
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Materials Today Communications
·
2022
·
IF 3.662
Junyue Shan,Xianliang Wu,Caifang Li,Jiwei Hu,Zhenming Zhang,Huijuan Liu,Pinhua Xia,Xianfei Huang
In recent years, semiconductor materials have shown excellent potential in the field of photocatalytic degradation of antibiotics. To prepare a photocatalyst with excellent performance, an Fe 3 O 4 /rGO/Co-doped ZnO/g-C 3 N 4 tetrameric hybrid photocatalyst was successfully prepared for the first time by means of chemical precipitation using graphene oxide as the precursor. The developed quaternary photocatalyst was used for the degradation of oxytetracycline hydrochloride (OTC), and its photocatalytic activity was investigated. The structure and morphology of the composites were characterized by XRD , SEM, HR-TEM, ESR, N 2 adsorption, PL spectroscopy and UV-Vis DRS . The effects of different parameters on the degradation process were studied by the response surface method and artificial intelligence. The results showed that Fe 3 O 4 /rGO/Co-doped ZnO/g-C 3 N 4 was successfully synthesized. Under optimal conditions, the degradation rate of OTC was approximately 82% (the Fe 3 O 4 /rGO/Co-doped ZnO/g-C 3 N 4 dose was 0.16 g, the pH was 7.0, the initial concentration of OTC was 30 mg/L, and the visible light irradiation time was 70 min). pH is the most influential variable for OTC removal. At the same time, the degradation rate of OTC remained above 50% after 5 times of recycling, indicating that Fe 3 O 4 /rGO/Co-doped ZnO/g-C 3 N 4 photocatalyst had good stability and recoverability. In addition, the results of ESR and radical trapping experiments showed that·O 2 - and·OH were the main active species in the OTC removal process.
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LANGMUIR
·
2023
·
IF 3.9
Yuru Min,Lei Wang,Chenyao Yuan,Honglei Liu,Xiaole Gong,Mengyu Cao,Jiang-Tao Xu,Jingquan Liu
Indoor gaseous formaldehyde is the main environmental pollutant that can cause fatal threats to human health. A number of physical and chemical methods have been developed to tackle this issue. However, the existing methods are still unsatisfactory to meet the requirement of sustainable development owing to the flaws of low efficiency and reversible or second pollution. Herein, a chemical method based on a nucleophilic reaction between hydrazine and aldehyde that generates the only by-product of H2O is designed for the removal of formaldehyde. 1-Pyrenebutyric hydrazide was synthesized by a simple esterification reaction and then self-assembled on reduced graphene oxide (rGO) with a large surface area by forming π–π stacking to obtain a composite for chemical removal of gaseous formaldehyde under ambient conditions. In a practical test, the formaldehyde removal rate could reach 91% of the theoretical value, which meets the requirement for commercial formaldehyde removal applications. After 10 times recycling, the formaldehyde removal rate still remains as high as 85%. Moreover, the composite could be regenerated in weak acidic media, which greatly reduce the manufacturing cost in practical applications.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Shuai Wang,Changhao Yao,Yifeng Cai,Yang Yang,Huiyuan Ma,Baojiang Jiang,Jun Ma
In this study, α-Fe 2 O 3 /rGO was smoothly synthesized by a one-step method and employed to activate persulfate (PS) for the degradation of Bisphenol A (BPA) under sunlight. During the degradation experiment, the degradation rates of BPA for PS, α-Fe 2 O 3 /8% rGO, and α-Fe 2 O 3 /8% rGO/PS were 6.6%, 47.6%, and 99.1%, respectively, indicating that the introduction of α-Fe 2 O 3 /rGO and PS significantly enhanced the photocatalytic efficiency because that photocatalytic process and PS activation coupling system not only inhibited the recombination of photo-induced carrier pairs, but also reduced the energy consumption of PS activation. Moreover, electron spin resonance spectroscopy (ESR) and trapping experiments were utilized to explore the active species generated during the reaction. The results showed that •OH and •SO 4 2- were the principal oxidative species in this reaction system. These results showed that Fe-loaded rGO has great potential for activating PS to decompose pollutants in water.
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TALANTA
·
2023
·
IF 6.1
Mengjiao Li,Yu Wu,Chenxi Ke,Zichen Song,Meie Zheng,Qingjie Yu,Hongda Zhu,Huiling Guo,Hongmei Sun,Mingxing Liu
In this study, an ultrasensitive unlabeled electrochemical immunosensor for the detection of cardiac troponin I (cTnI) was developed based on Pt/Au modified B,S,N co-doped reduced graphene oxide (Pt/Au–B,S,N-rGO) as a signal amplification platform. First-principles calculations were employed to analyze the electron density of states of Pt/Au–B,S,N-rGO, revealing an increase in the electron density of the graphene oxide (GO) states. Furthermore, scanning electron microscopy (SEM), X-ray photoelectron diffraction spectroscopy (XPS), and electrochemical detection were used to successfully construct and analyze Pt/Au–B,S,N-rGO. The results showed that B,S,N-rGO exhibited good electrochemical activity, and the Au/Pt NPs demonstrated excellent catalytic properties, which provided a strong foundation for achieving high-sensitivity detection. Moreover, the constructed unlabeled electrochemical immunosensor had an ideal linear range (0.1 pg/mL∼50 ng/mL) and detection limit (0.082 pg/mL). In human serum detection, the results of this immunosensor were essentially similar to the ELISA results for the same samples, which suggested that the immunosensor had a promising clinical application prospect for the detection of cTnI.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
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IF 9.9
Mohammed A. Al-Tahan,Baoji Miao,Sankui Xu,Yange Cao,Mengyao Hou,Mohamed R. Shatat,Muhammad Asad,Yanwei Luo,Aml E. Shrshr,Jianmin Zhang
The specific energies and energy densities of lithium–sulfur (Li-S) batteries are influenced by various cell parameters, including the sulfur loading, the sulfur weight percentage in the cathode, and the electrolyte/sulfur ratio. An In 2 S 3 /Bi 2 S 3 @rGO heterostructure was obtained by growing indium sulfide nanoparticles on the surface of bismuth sulfide nanoflowers in a graphene oxide (GO) solution via a one-step solvothermal approach. This structure was introduced as a modified separator/dual-layer sulfur cathode for Li-S batteries. The Bi 2 S 3 /In 2 S 3 heterointerfaces act as active sites to speed up interfacial electron transfer, along with the entrapment, diffusion, and transformation of lithium polysulfides. A Li-S cell containing a dual-layer sulfur cathode (thin layer of In 2 S 3 /Bi 2 S 3 @rGO sandwiched between two thick layers of sulfur) and coupled with an In 2 S 3 /Bi 2 S 3 @rGO-coated separator suppressed the polysulfide shuttle effect. The cell based on the dual-layer sulfur cathode technology and operated at a current rate of 0.3C achieved a high capacity (7.1 mAh cm −2 ) after the 200th cycle, giving an electrolyte/sulfur ratio (10 µL mg −1 ) under a high sulfur loading (11.53 mg cm −2 ). These results demonstrate the unique nature of the dual-layer sulfur cathode technique, which can yield high energy density Li-S batteries with high sulfur loadings and low electrolyte/sulfur ratios.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
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IF 5.774
Zheng Zhang,Xiao Du,Qiang Wang,Fengfeng Gao,Tongtong Jin,Xiaogang Hao,Pengfei Ma,Jun Li,Guoqing Guan
A scalable three-dimensional (3D) porous composite electroactive film consisting of λ-MnO 2 , reduced graphene oxide (rGO) and calcium alginate (Ca-alg) was successfully fabricated and employed for the selective extraction of Li + ions with low concentration via an electrochemically switched ion exchange (ESIX) technology. The Li + ion adsorption capacity of the obtained λ-MnO 2 /rGO/Ca-alg composite electroactive film reached as high as 32.7 mg g −1 and more than 90% of its equilibrium adsorption capacity was achieved in 1 h. The λ-MnO 2 /rGO/Ca-alg composite electroactive film displayed evident selectivity towards Li + ions. The separation factors for Li + /Na + and Li + /Mg 2+ reached 1040.57 and 358.96, respectively, while tested in simulated brine. The composite film also showed superior electrochemical stability, and the normalized ion exchange capacity retained at 98.3% of its initial value even after 100 successive cycles. The excellent Li + ion recovery performance of the obtained composite film should be attributed to its low ion transfer resistance owing to the porous network structure and the potential-responsive ion-pumping effect in the ESIX process. In addition, a large-scale of such a composite electroactive film could be effectively fabricated by controlling the spreading area of the mixed solution consisting of λ-MnO 2 , rGO and alginate binder. It is expected that such a scalable 3D porous composite film could be a promising alternative for the recovery of lithium ions from salt lake brine.
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BIOSENSORS & BIOELECTRONICS
·
2019
·
IF 9.518
Weiran Mao,Junlin He,Zhiyong Tang,Chengli Zhang,Jun Chen,Jia Li,Chao Yu
A novel electrochemical immunosensor was proposed for the detection of monocyte chemoattractant protein-1 (MCP-1), a biomarker of cardiovascular disease. Due to thionine (Thi) possessing electroactive redox properties, a one-step approach was utilized to synthesize a reduced graphene oxide-tetraethylene-thionine-Au (rGO-TEPA-Thi-Au) nanocomposite at room temperature using the synergistic effect of Thi and rGO-TEPA towards HAuCl 4 . We obtained the excellent matrix material , which immobilized more primary antibody MCP-1-Ab 1 on rGO-TEPA on a modified glassy carbon electrode (GCE). To further enhance the sensitivity of the sensor, a novel signal generation and amplification strategy was developed for detection. RuPdPt trimetallic nanoalloy particles (RuPdPt TNPs), a novel nanomaterial , were synthesized by a one-pot method, displayed a uniform morphology as well as good electrochemical activity and bound with the secondary antibodies against MCP-1 via the Pt-NH 2 bond. Most importantly, RuPdPt TNPs have a significant ability to catalyze H 2 O 2 to produce an electron. The electrochemical signal was highly amplified because the electrochemical signal was primarily derived from the synergistic catalysis of H 2 O 2 by RuPdPt TNPs and recorded by chronoamperometry . Under the optimal conditions, this newly designed biosensor exhibited sensitive detection of MCP-1 in the range from 20 fg mL −1 to 1000 pg mL −1 , with a detection limit of 8.9 fg mL −1 (based on a S/N = 3). Additionally, the designed immunosensor showed acceptable selectivity , reproducibility and stability. This immunosensor is a promising strategy for analyzing clinical serum samples in the future.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Xunzhi Deng,Ze Liao,Jing Lu,Haiou Li,Xianxin Zhu,Yilin Liu,Qinyao Li,Danyi Deng,Chao Huang,Zhoufei Luo
The presence of alkylphenolic residues in vegetables could pose a potential food safety risk for humans. The residues of alkylphenols in bean sprouts have not been reported. Magnetic dispersion solid phase extraction (MD-SPE) followed by ultra performance liquid chromatography-tandem mass spectrometry was developed for detecting alkylphenol residues in sprouts. The Fe 3 O 4 @rGO@poly 3-aminophenol composite was first synthesized and used as an effective and regenerate adsorbent for MD-SPE. This method features minimal use of organic reagents, high extraction efficiency, easy recovery via magnetic separation, and the reusability of the adsorbent. The magnetic composite was characterized using X-ray powder diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, and transmission electron microscopy. For optimization of the extraction process, the Plackett-Burman factorial design was employed to to fine-tune multiple parameters of MD-SPE. Additionally, the sensitivity of UPLC-MS/MS enabled the precise quantification of alkylphenols in the sprout samples. This analysis yielded high linearities (R 2 > 0.9989) and recoveries (90.4 %–108.5 %) at three different spiked levels. a minimal matrix effect (7.5 %–12.4 %), impressive limits of detection (0.89–13.62 pg/mL), and reliable reproducibility (intra-day: 2.0 %–13.5 %; inter-day: 0.7 %–11.6 %) were obtained. Thus, a new method was successfully employed for analyzing alkylphenolic residues in vegetables samples, making it a valuable tool for ensuring food safety.
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POLYHEDRON
·
2024
·
IF 2.4
Firdous Bibi,Adeel Ahmed,Yathrib Ajaj,Ahmed Abd Al-Sattar Dawood,Muhammad Usman,Abdullah Alodhayb,Saikh Mohammad,Zubair Ahmad,Ambreen Kalsoom,Shahid Iqbal
Herein, we have synthesized Ni and Mn co-doped ZnFe 2 O 4 ferrites using the simple co-precipitation method and their nanocomposites (NCs) with 10 % rGO using the ultra-sonication route. The structural investigation revealed the successful formation of single-phase ZnFe 2 O 4 NPs with cubic spinel ferrite geometry. The crystallite size was determined to be in the range of 21 nm to 28 nm. The current–voltage (I-V) analysis revealed that Ni and Mn co-doping and the addition of rGO nanosheets in ZnFe 2 O 4 NPs boosted the electrical responses of the fabricated Zn 1-x Ni x Fe 2-y Mn y O 4 /rGO NCs. The BET analysis indicates an increase in the surface area of Zn 1-x Ni x Fe 2-y Mn y O 4 /rGO NCs (132 m 2 /g) that might be attributed to the inclusion of rGO nanosheets, which prevents the NPs from agglomeration. The photocatalytic evaluation of the pristine ZnFe 2 O 4 NPs, Ni and Mn co-doped Zn 1-x Ni x Fe 2-y Mn y O 4 NPs, and Zn 1-x Ni x Fe 2-y Mn y O 4 /rGO NCs photocatalysts was tested by photodegradation of malachite green (MG) dye under sunlight irradiation. Results exhibited improved photocatalytic responses and degraded 94.6 % of MG dye in 45 min using Zn 1-x Ni x Fe 2-y Mn y O 4 /rGO NCs, which was much higher compared to the Ni and Mn co-doped Zn 1-x Ni x Fe 2-y Mn y O 4 NPs (58.7 %) and pristine ZnFe 2 O 4 NPs (38.3 %). The increased degradation potential of Zn 1-x Ni x Fe 2-y Mn y O 4 /rGO NCs was accredited to the highly conducting nature and 2D nano-sheets of rGO, which efficiently inhibited the recombination of charge carrier species. Ultimately, the remarkable photocatalytic capability exhibited by Zn 1-x Ni x Fe 2-y Mn y O 4 /rGO NCs implies that the synthesized NCs could have auspicious practical applications in the elimination of dyes from wastewater.
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PROGRESS IN ORGANIC COATINGS
·
2024
·
IF 6.5
Wenli Bao,Yuanjun Liu,Xiaoming Zhao
To solve the problem of electromagnetic radiation pollution, it is especially important to develop electromagnetic wave-absorbing materials with excellent performance. The preparation of composite multifunctional textile materials with excellent wave-absorbing properties is one of the research hotspots for practical personal protection applications. In this work, PPy/Fe 3 O 4 /rGO polyester/cotton composite fabrics were prepared by impregnation, chemical reduction, chemical co-precipitation and in situ polymerization. When the thickness is 0.97 mm, the minimum reflection loss ( RL min ) of PPy/Fe 3 O 4 /rGO polyester/cotton composite fabric is −12.12 dB, and the effective absorption bandwidth (EAB) is 4.7 GHz, which is excellent in wave absorption. Meanwhile, the PPy/Fe 3 O 4 /rGO polyester/cotton composite fabrics have excellent UV resistance (UV transmittance ratio of UVA and UVB bands as low as 0.02 %, UPF value of 100+), antistatic properties (static voltage half-life of 0.2 s), and excellent thermal management properties (thermal conductivity as low as 0.05796 W/(m·K)), and so on. The PPy/Fe 3 O 4 /rGO polyester/cotton composite fabrics prepared in this study are suitable for a variety of application scenarios, such as individual electromagnetic protection, individual protection in extremely cold environments, and individual heating physiotherapy, which is of great reference significance for the research of wearable individual protective textile materials.
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