ACS Applied Materials & Interfaces
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2022
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IF 10.383
Chenglong Li,Shuang Wang,Yinghe Cui,Xiaodong Wang,Zhipeng Yong,Dan Liang,Yue Chi,Zhe Wang
The restacking of the MXene film limits its development to the high energy density of flexible supercapacitors. In order to promote the application of MXene films in portable electronic devices and miniaturized energy storage devices, it is necessary to increase the area capacitance of MXene films for the pursuit of high energy density. The introduction of α-Fe2O3–C–MoS2-PEDOT:PSS (FMP) into MXene significantly increases the area capacitance. Considering the large number of active sites on the surface of MXene and its excellent hydrophilicity, FMP can be well-compounded with MXene, and the accumulation and loss of FMP can be prevented. Meanwhile, it can reduce the performance degradation caused by the accumulation of MXene’s own structure and greatly increase its capacitance value. It is worth mentioning that the MXene/FMP/MXene (M/FMP/M) sandwich structure on the carbon cloth is reasonably designed to show excellent performance. Therefore, the best M/FMP/M electrode could attain a breakthrough in the area capacitance (2700 mF cm–2 and 541 F g–1). At the same time, the electrode maintains a fine rate capability and fabulous flexibility. In addition, the symmetrical supercapacitors also show a significant energy density of 371 μW h cm–2 (12.36 W h·kg–1), making this sandwich structure electrode a promising candidate for high-energy-density devices.
研究领域:
材料科学
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储能技术
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纳米科技
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电化学
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柔性电子学
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高影响因子
FOOD RESEARCH INTERNATIONAL
·
2026
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IF 8
Xuejing Liu,Zhaojun Zheng,Yuanfa Liu
A novel method for determining α, β-unsaturated aldehydes (α, β-UAs) in edible oils was proposed, utilizing 2,4-dimethylpyrrole (2,4-DMP) derivatization followed by UV–vis analysis. The optimal detection wavelengths were identified as 580 nm for α, β-monounsaturated aldehydes (α, β-MUAs) and 680 nm for α, β-diunsaturated aldehydes (α, β-DUAs). The reaction mechanism was confirmed by Fukui function and hydrogen nuclear magnetic resonance ( 1 H NMR) analysis, demonstrating formation of enamine as the final product. Derivatization conditions were optimized for rapid and reproducible results. The proposed method demonstrated excellent sensitivity, with limits of detection (LOD) and quantification (LOQ) for α, β-MUAs at 0.0038 μmol/mL and 0.0117 μmol/mL, and for α, β-DUAs at 0.0043 μmol/mL and 0.0129 μmol/mL, respectively. Compared to the p-anisidine value ( p-AV ) and high-performance liquid chromatography (HPLC) based methods, the proposed method showed several advantages in shorter derivatization time, simplified operation, high throughput potential and lower toxicity. This method provides an efficient tool for α, β-UAs detection, which is crucial for ensuring oil quality and safety.
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ACS Applied Materials & Interfaces
·
2026
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IF 8.2
Jing Wang,Weida Shi,Minghui Qiu,Juanjuan Wen,Xianfu Chen,Yiqun Fan
Ceramic tight ultrafiltration (UF) membranes exhibit excellent chemical and thermal stability. However, increased pore size and limited separation accuracy caused by high temperature sintering remain challenges in their preparation and application. In this study, a facile lattice-doping strategy using Fe-doped sol–gel precursors was developed to fabricate α-Al2O3 tight UF membranes. Fe incorporation effectively promoted the γ → α phase transformation at a reduced temperature (950 °C), suppressed grain growth, and produced smaller and more uniformly distributed pores with an average size of 5.5 nm. Increasing Fe content further enhanced surface hydrophilicity, corrosion resistance in biotic systems, and pure-water permeability (130 L·m–2·h–1·bar–1). Nevertheless, excessive Fe loading (>10%) resulted in phase separation and pore size heterogeneity. The optimized 10% Fe-doped α-Al2O3 membrane exhibited outstanding separation performance, achieving a BSA rejection of 99.9% and a permeance of 80 L·m–2·h–1·bar–1, nearly double the value of the undoped membrane. It also showed a significantly improved normalized flux and a flux recovery ratio exceeding 80%, demonstrating excellent antifouling capability. Similar antifouling and high removal were also observed in humic acid separation. These compelling features highlight its potential for efficient water purification applications.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
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IF 8.7
Min Ma,Taiyu Liu,Chun Wang,Yunqi Liu,Wanyao Tan,Yingying Zheng,Wenhui Fan,Yue Su,Hong Li,Mingxue Li,Yuemi Zhou,Yongqi Zhang
The mesoporous polydopamine-loaded α-N-thiosemicarbazone was prepared. • A multifunctional photothermal dual-network hydrogel was fabricated. • Hydrogel exhibits injectability, self-healing, and tissue adhesion properties. • It possessed both photothermal antibacterial activity and wound-healing ability. • Hydrogel exhibits antioxidant and excellent biocompatibility. Refractory wounds caused by bacterial infections pose a severe clinical challenge, highlighting the urgent need for wound dressings with both excellent antibacterial activity and advanced tissue regeneration capabilities. Herein, a multifunctional photothermal antibacterial hydrogel (GHUS-mPDA@HL) was fabricated using mesoporous polydopamine-loaded α-N-thiosemicarbazone (mPDA@HL) nanoparticles, ureido-pyrimidinone grafted gelatin (GHU) and sodium alginate as primary components. The hydrogel network was constructed via quadruple hydrogen bonding and an interpenetrating polymer network, rendering it injectable, self-healing, and tissue-adhesive properties. The mPDA@HL nanoparticles combine the antibacterial and antioxidant properties of α-N-heterocyclic thiosemicarbazone compound (HL) with intrinsic photothermal and antibacterial capacity of mesoporous polydopamine (mPDA). Furthermore, under 808 nm near-infrared irradiation, GHUS-mPDA@HL hydrogel exhibits excellent photothermal performance, enabling efficient bacterial eradication, inflammatory mitigation, and accelerated wound healing. The GHUS-mPDA@HL hydrogel achieves synergistic antibacterial effects against both Gram-negative Escherichia coli (99.98%) and Gram-positive Staphylococcus aureus (99.99%) under near-infrared irradiation. Additionally, the hydrogel showed excellent biocompatibility and effective reactive oxygen species scavenging ability. In a full-thickness skin wound mouse model, GHUS-mPDA@HL hydrogel under NIR irradiation remarkably accelerates wound repair, with a healing rate of 98.49% within 10 days. It also promotes collagen deposition and angiogenesis to further facilitate wound closure. Overall, this GHUS-mPDA@HL hydrogel presents an excellent antibacterial activity and potent wound-healing promotion effects, providing a promising strategy for the development of intelligent wound dressings.
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JOURNAL OF POWER SOURCES
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2026
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IF 8.4
Zerui Li,Zehui Zhang,Wenxin Zhang,Xiufeng Tang,Jiong Zhang,Zixuan Wu,Jianyi Luo
Aqueous zinc-ion batteries (ZIBs) are promising for energy storage due to their high safety, but Zn 2+ distribution characters in cathodes remains poorly understood. In this study, we comprehensively map the overall Zn 2+ distribution profiles and reveal localized nonuniform distribution characteristics in a representative α-MnO 2 cathode. Two striking features of the nonuniform distribution are identified: the ‘bottom effect’ characterized by substantially higher Zn concentration at the electrode bottom, and ‘inactive areas’ where Zn concentration is extremely low. The bottom effect occurs only under specific initial electrode capacity and nonuniform discharging current-density distribution. Inactive areas are distinguished by the absence of Zn 4 (SO 4 ) (OH) 6 ·xH 2 O (ZSH) nanosheets on the surface, which probably results from poor wettability with the aqueous electrolyte due to lack of hydrophilic α-MnO 2 . This conceptual framework offers new insights for developing strategies to mitigate these issues and enhance electrode performance.
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POLYMER
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2026
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IF 5.1
Changlei Yang,Liqiong Zhou,Keke Cao,Yuhao Liu,Yufei Liu,Min He,Shuhao Qin,Jie Yu
Currently, the copolymer modification of PA56 mainly focuses on random copolymerization with other α-crystal form polyamides. In contrast, research on the structure and properties of PA54 remains insufficient, and its application is significantly limited by poor thermal stability. In this study, PA5654 alternating copolymer was prepared, and the hydrogen bond structure, molecular chain conformation, and α-γ Brill transition were investigated. Interestingly, after undergoing the Brill transition, PA5654 can form two crystal forms (γ and α). Although the underlying degradation mechanism remains unchanged, the PA5654 copolymer significantly suppresses the amide-bond scission observed in PA54. Compared with PA54, its initial decomposition temperature ( T 5% ) and maximum decomposition temperature ( T max ) increased by 19 °C and 71 °C, respectively, indicating that its thermal stability has been effectively improved.
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ATMOSPHERIC ENVIRONMENT
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2026
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IF 3.8
Shijie Liu,Jie Wang,Zhifei Wang,Feiyong Chen,Yusi Liu,Xiaofeng Wei,Youmin Sun,Zaifeng Wang,Guiqin Zhang
α-Pinene is a key precursor in the formation of secondary organic aerosols (SOA) in the atmosphere. SOA formation via atmospheric photooxidation of α-pinene under varying nitrogen oxides (NO x ) and ammonia (NH 3 ) concentrations was investigated in a laboratory smog chamber, with a focus on SOA mass concentration and chemical composition. The experimental results demonstrated that increasing NO x concentrations from 30 to 80 ppb reduced the α-pinene SOA yield from 15.5% to 9.0%. In contrast, the presence of NH 3 enhanced the SOA yield. The investigation revealed that the suppressive effect of NO x on SOA yield gradually weakened with increasing NH 3 concentration, whereas the promoting effect of lower NH 3 concentrations on SOA yield was more pronounced under lower NO x conditions. The chemical composition of SOA revealed that NH 3 promoted the formation of nitrogen-containing organic compounds (NOCs). Furthermore, NO x increased the abundance of nitrogen-containing functional groups within NOCs. A comparison of the volatile components of SOA indicated that the increase in volatile organic component (VOC) and intermediate-volatility organic component (IVOC) contents with increasing NO x concentration was responsible for the suppression of SOA formation. Furthermore, the enhancement of SOA yield by NH 3 was mainly attributed to the increase in IVOC and semi-volatile organic component (SVOC) contents. Overall, these results demonstrated that NH 3 and NO x exerted distinct effects on α-pinene-derived SOA formation. These findings provide valuable insights into the mechanism of SOA formation under complex pollution conditions involving the coexistence of NO x and NH 3 .
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CHINESE JOURNAL OF CATALYSIS
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2026
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IF 17.2
Peixin Zhu,Mengyao Xiao,Xixi Chen,Jingsong Luo,Zhong Fang,Long Chen,Huinan Zhao,Chun He,Shuanghong Tian
While facet engineering and heterostructure construction are recognized as effective strategies for enhancing catalytic performance through defect creation, their integration remains scarce and challenging. This study develops a mild urea-assisted thermal strategy to construct an oxygen vacancy (OV)-rich α -MnO 2 (310)/Mn 3 O 4 heterojunction (Mn400-0.125U), comprising 48.6% α -MnO 2 with preferentially exposed (310) facets and 51.4% Mn 3 O 4 . The low OV formation energy on (310) facets coupled with heterojunction interfaces effects leads to a high OV concentration. Mn400-0.125U demonstrated exceptional catalytic ozonation performance, achieving a sulfamethoxazole degradation rate constant (7.7×10 −2 min −1 ), which is 1.8-, 1.6-, and 3.3-fold higher than those of α -MnO 2 , Mn 3 O 4 , and single ozonation, respectively. Operational advantages include ultralow catalyst dosage (0.1 g/L), broad pH adaptability (3.5–10.5), and remarkable resilience against aqueous matrix interference (≤ 12.4% efficiency loss). Both experimental and theoretical calculations demonstrate that the abundant OVs, combined with the proper hydrophilicity of Mn400-0.125U, synergistically trigger barrier-free activation and decomposition of ozone, subsequently generating a series of reactive species via chain reactions. A hybrid oxidation regime was identified where the non-radical pathway mediated by electron-transfer, O* (surface oxygen atoms), and 1 O 2 predominates over radical pathways (•O 2 − /•OH). This work establishes a facile coupled modulation protocol for creating defect-rich manganese oxides applied in catalytic ozonation of emerging contaminants.
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高影响因子
Food & Function
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2026
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IF 6.3
Ziyuan Zhou,Xiaxia Pan,Jiali Ni,Zhuoqi Lou,Yangfan Shen,Shiman Jiang,Xiangmin Dong,Fengjiao Wang,Yanfei Chen,Lanjuan Li
Existing evidence indicates that pre-existing metabolic dysfunction-associated steatotic liver disease (MASLD) confers susceptibility to acute liver injury (ALI). Nevertheless, the underlying mechanism prompting ALI risk in such condition is not fully uncovered yet. Gut dysbiosis has been well-documented in MASLD patients which prompts us to hypothesize that gut dysbiosis may serve as a contributing factor and regulating target to ALI susceptibility. A case-control study was performed and verified the increased risk of ALI in MASLD patients. Mice pretreated with MASLD mice/patients-derived fecal microbiota transplantation (FMT), demonstrated worsened ALI after D-GalN/LPS injection. We identified significant gut dysbiosis with decreased microbial α-diversity, beneficial genus lactobacillus, increased potential harmful bacteria Campylobacter and helicobacter. Probiotic Akkermansia muciniphila (A. muciniphila) was reported to improve gut dysbiosis. Thus, we tested the effect of A. muciniphila on ALI mice pretreated with MASLD mice-derived FMT. A. muciniphila significantly ameliorated the worsened ALI and improved gut dysbiosis. Transcriptomic analysis reveled that A. muciniphila restored the impaired liver PPAR-α signaling, alleviating the aggravated NF-κB signaling and downstream inflammation response in liver. Specifically, A. muciniphila restored the decreased abundance of PPAR-α agonist daidzein in colon, thereby restoring PPAR-α activation and inhibiting NF-κB signaling in liver. Daidzein is also capable to ameliorate ALI aggravated by MASLD-associated dysbiosis, accompanied by PPAR-α activation and NF-κB inhibition. Our findings revealed that gut dysbiosis in MASLD increased the risk of ALI. A. muciniphila exhibited preventive potential for MASLD patients to reduce ALI risk. Daidzein/PPAR-α/NF-κB signaling is important to maintain host resistance to hepatoxic challenge.
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ACS Applied Materials & Interfaces
·
2026
·
IF 7.8
Li Xiang,Jiachi Xu,Yukang Lin,Xianjing Xiang,Qiangqiang Jiao,Sainan Zhu,Wenhui Zhang,Yuting Qin,Yuping Chen
Fibrotic tumor microenvironment driven by activated hepatic stellate cells (aHSCs) and cancer-associated fibroblasts poses a formidable challenge to antitumoral drug delivery in hepatocellular carcinoma (HCC) by promoting angiogenesis, immunosuppression, and dense extracellular matrix barrier. Overcoming this fibrosis-associated delivery resistance requires nanotherapeutic systems to not only target the stromal compartment but also adapt their structure within the tumor matrix to improve deep penetration. Herein, we report a fibroblast activation protein-α (FAP-α)-responsive, size-transformable lipid nanoparticle platform with integrated stromal targeting, enzymatic activation, and intracellular delivery capacity for enhanced drug penetration and stromal remodeling in fibrotic HCC. This developed system, denoted as SOR/DOX@GPA-LNP, is co-loaded with sorafenib and doxorubicin and engineered with three key features: (i) a FAP-α-cleavable GPA peptide linker for TME-specific activation, (ii) FAP-α-mediated targeting of aHSCs, and (iii) a PAMAM core-mediated proton sponge activity to facilitate endosomal escape. Physicochemical characterization demonstrates that GPA-LNPs possess uniform size distribution, high colloidal stability, pH-responsive release behavior, and favorable heme- and cyto-compatibility. In vitro studies confirmed their selective aHSC-targeting ability, while in vivo imaging showed enhanced accumulation and retention in nude mice bearing subcutaneous tumors and orthotopic tumor-bearing mice. GPA-LNPs exhibited size reduction (from 170.5 to 146.3 nm) upon exposure to FAP-α, which significantly improved transport in three-dimensional HCC/aHSC spheroid models and increased deeper intratumoral accumulation. This size-transformable property establishes a direct structure–property–function relationship linking FAP-α enzymatic responsiveness with enhanced stromal penetration. Functionally, SOR/DOX@GPA-LNPs simultaneously suppressed aHSC activation, disrupted the fibrotic stromal barrier, and delivered cytotoxic agents to tumor cells. In the orthotopic HCC model, SOR/DOX@GPA-LNPs achieved superior antitumor efficacy, improved stromal remodeling and reduced systemic toxicity compared to nonresponsive counterparts. Overall, this work presents a versatile strategy that couples TME-responsive size adaptability with dual-action payloads, offering a compelling approach to navigate the complexities of fibrotic HCC therapy.
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Biochar
·
2026
·Vol. 8
·期 1
·113
·
IF 15.1
Zhang Jian,Xie Jiafang,Zhu Shuhui,Yang Jiacheng E.,Weng Bo,Zheng Yuming
Biochar optimized with oxygen-containing functional groups is believed to be beneficial for peroxymonosulfate (PMS) activation, and biochar-loaded Co 3 O 4 -based catalysts are expected to be one of the most promising PMS activators for the efficient removal of organic pollutants. Nevertheless, the real active sites on Co 3 O 4 catalysts are still in debate due to insufficient experimental evidence. Herein, Co 3 O 4 growing on the oxygen-containing functional groups optimized rice husk biochar (RHBA) was synthesized (RHBA@Co 3 O 4 ), and RHBA800@25Co 3 O 4 + PMS system achieved complete degradation (100%) of refractory levofloxacin (LFX) within 4 min. The superior catalytic performance was suggested to be attributed not only to the uniform dispersion of Co 3 O 4 , but also to the transformation of lattice oxygen in Co 3 O 4 , which was found to play an important role in the catalytic process by inducing the formation of Co 3 O 4−α –OH. Meanwhile, density functional theory (DFT) calculations indicated that the adsorption energy ( E ads ) of PMS on Co 3 O 4−α –OH was far lower than that on Co 3 O 4 . Moreover, both radical and non-radical pathways were indicated to be involved during the degradation process. Additionally, the practical application of RHBA@Co 3 O 4 was investigated using various antibiotics, actual water environments, and fixed-bed reactors. The results showed that it possessed good practical degradation performance and significantly reduced the toxicity of intermediate products. This work provides a fresh insight into the catalytic mechanism of RHBA800@25Co 3 O 4 for PMS activation and wastewater treatment, offering a new perspective on the catalytic mechanism of Co 3 O 4 -based materials. Highlights
RHBA800@25Co 3 O 4 exhibited ultrafast antibiotics degradation via peroxymonosulfate activation.
Inspired formation of Co 3 O 4−α –OH by lattice oxygen induction was explored.
Ecological safety of levofloxacin degradation products was verified through antibacterial experiments.
Graphical The alternative text for this image may have been generated using AI.
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JOURNAL OF MEDICINAL CHEMISTRY
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2026
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IF 7.3
Junjie Zhang,Fawei He,Yurui Wang,Peng Jiang,Jiongwen Qin,Meng Liu,Jiawei Yao,Dongting Zhangsun,Meng Li,Sulan Luo,Yong Wu
The surge in multidrug-resistant (MDR) pathogens necessitates novel therapeutic strategies. Here, we report the rational design of C4-VG7, an N-terminal butyrylated lipopeptide engineered from a compact, cationic, helix-compatible segment of the marine conotoxin αO-GeXIVA. Through stepwise structural optimization─from constrained cyclic prototypes to lipidated derivatives─C4-VG7 was identified as a lead candidate with potent, broad-spectrum activity against MDR ESKAPE pathogens, including clinical isolates (MIC ≈1 μM). Mechanistically, C4-VG7 exhibits multimodal bactericidal action: C4-tail-mediated membrane depolarization is consistent with early membrane disruption followed by intracellular DNA association and oxidative stress. In murine models of MRSA and Acinetobacter baumannii infections (skin and peritonitis), C4-VG7 achieved efficacy comparable to polymyxin B with significantly reduced hepatonephrotoxicity. Thus, C4-VG7 represents a systemically viable, well-tolerated candidate for combating MDR ESKAPE infections.
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