COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2023
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IF 5.2
Chao Su,Bin Pei,Peilun Shen,Qifang Zheng,Jinpeng Cai,Dianwen Liu
To solve the problem of depression failure caused by xanthate pre-adsorption, this paper comprehensively studies the mechanism and characteristics of L -cysteine (L-C) adsorption on the surface of galena with or without xanthate through micro-flotation, X-ray photoelectron spectroscopy (XPS), inductively coupled plasma-optical emission spectrometry (ICP-OES), field emission scanning electron microscope-energy dispersive spectroscopy (FESEM-EDS), time of flight secondary ion mass spectrometry (ToF-SIMS), zeta potential , UV–visible spectrum, and contact angle experiments. SBX has a significant effect on the adsorption behavior of L-C on the surface of galena. The micro-flotation results showed that the L-C has very good depression effect on galena. However, this is invalid when sodium butyl xanthate (SBX) is preferentially introduced. L-C can be adsorbed on galena through the reaction of -SH and -NH 2 with exposed lead sites. In addition, the lead species dissolved from the surface of galena can be re-adsorbed after complexing with L-C in solution. However, L-C can hardly interact with the surface of galena pre-treated by SBX, and it is only adsorbed by electrostatic force in the form of [Pb(C 3 H 7 NO 2 S)] 2+ and [PbOH(C 3 H 7 NO 2 S)] + complexes. This study is expected to achieve cyanide free separation of Cu-Pb bulk concentrate.
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高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 18
·2523
·
IF 5.3
Yang Liu,Xuepeng Zhao,Yuhui Ma,Wanqin Dai,Zhuda Song,Yun Wang,Jiaqi Shen,Xiao He,Fang Yang,Zhiyong Zhang
As one of the most widely used nanomaterials, CeO2nanoparticles (NPs) might be released into the aquatic environment. In this paper, the interaction of CeO2NPs and Ce3+ions (0~10 mg/L) with duckweed (Lemna minorL.) was investigated. CeO2NPs significantly inhibited the root elongation of duckweed at concentrations higher than 0.1 mg/L, while the inhibition threshold of Ce3+ions was 0.02 mg/L. At high doses, both reduced photosynthetic pigment contents led to cell death and induced stomatal deformation, but the toxicity of Ce3+ions was greater than that of CeO2NPs at the same concentration. According to the in situ distribution of Ce in plant tissues byμ-XRF, the intensity of Ce signal was in the order of root > old frond > new frond, suggesting that roots play a major role in the uptake of Ce. The result of XANES showed that 27.6% of Ce(IV) was reduced to Ce(III) in duckweed treated with CeO2NPs. We speculated that the toxicity of CeO2NPs to duckweed was mainly due to its high sensitivity to the released Ce3+ions. To our knowledge, this is the first study on the toxicity of CeO2NPs to an aquatic higher plant.
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PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2025
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IF 6.2
Zhennan Cui,Yigui Qiu,Yiming Zheng,Ning Ou,Ziyan Zhang,Jia Li,Wen Gu
A total of 45 l-menthol derivatives with thiosemicarbazide, semicarbazide, or thiazole structures were designed and synthesized, and the in vitro inhibitory activities were evaluated against seven plant pathogens. Some title compounds exhibited remarkable antifungal activities. Specifically, compound 4n demonstrated a significant antifungal effect against Sclerotinia sclerotiorum with an EC50 value of 1.03 mg/L, outperforming thifluzamide (1.32 mg/L). Furthermore, at a concentration of 200 mg/L, 4n displayed excellent protective (97.5%) and curative (95.7%) effects on S. sclerotiorum-infected carrots. In the phytotoxicity experiment, 4n exhibited no effect on the normal germination of carrot and mung bean seeds. Fluorescence imaging revealed a significant accumulation of reactive oxygen species (ROS) in mycelia treated with 4n. Additionally, 4n exhibited substantial inhibitory effects on the sclerotium formation and germination of S. sclerotiorum. A further mechanism study revealed that 4n could dose-dependently increase the cell membrane permeability and significantly inhibit the defense/respiration-related enzymes of S. sclerotiorum. The transcriptome analysis suggested that 4n could notably affect the gene expression related to the oxidation–reduction process and oxidoreductase activity. The enzyme inhibition assay and molecular docking studies implied that 4n could be a potential succinate dehydrogenase (SDH) inhibitor. These findings indicated that this class of l-menthol thiosemicarbazide derivatives holds promise as potential fungicides for the prevention and treatment of postharvest sclerotinia rot.
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PubMed
高影响因子
ANALYTICAL CHEMISTRY
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2025
·
IF 6.7
Hang Su,Shuo Huang,Jingming Lan,Xin Gao,Hongyan Yue
Chiral recognition and detection of enantiomer molecules are crucial for biochemical sensing and pharmaceutical applications. In this study, a rod-shaped left-handed cellulose nanocrystal (CNC, length of ∼75 nm and diameter of ∼10 nm) is extracted from strobili fibers of plane trees through acid hydrolysis. Then, octahedral CuO/C nanoparticles (∼450 nm) are synthesized via thermal decomposition of the Cu-MOF precursor. Finally, CNC@CuO/C is prepared by the self-assembly of CNC and CuO/C driven by solvent evaporation. The CNC@CuO/C electrode demonstrates a remarkable enantioselectivity to l-cysteine (l-Cys) and achieves a high sensitivity of 3.14 μA·mM–1 and a low detection limit (LOD) of 4.62 μM. The electrode exhibits an excellent anti-interference capability, reproducibility, repeatability (RSD < 5%), and stability (>90% after 15 days). This presents a sustainable approach to use renewable nanomaterials, and it also shows a promising potential for clinical diagnostics.
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DOI
PubMed
高影响因子
ENERGY & FUELS
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2025
·
IF 5.3
Yang Li,Xiaodong Shen,Xinlei Shi,Nanqin Zhou,Yinde Zhang,Bo Wang
Hydrate-based CO2 sequestration in submarine sediments is a promising large-scale carbon mitigation strategy. This study examined the effects of sediment grain size on CO2 hydrate formation kinetics, seepage behavior, and morphology evolution regulated by l-Methionine (l-Met) as a kinetic promoter, under controlled conditions of 3.6 MPa and 277.15 K, simulating the harsh environment of submarine organic-rich sediments. The experimental results demonstrate a nonunidirectional relationship between grain size reduction and sequestration enhancement. While finer sediments generally promote formation kinetics, the 98–138 μm quartz sand fraction exhibited optimal overall performance, achieving a CO2 consumption of 0.369 mol and the fastest growth rate (t90 = 58.027 min). This optimum reflects a balance between kinetic promotion and mass transfer, as evidenced by seepage tests showing that excessively fine sediments cause severe pore-throat clogging, leading to a marked reduction in effective permeability, whereas medium-grained systems exhibit the highest effective permeability. Mixed-grain systems display enhanced injectivity due to preferential flow pathways formed by coarse fractions. Visual observations reveal that CO2 hydrate in natural sea sands forms heterogeneously with nodular-like morphology. These findings offer theoretical guidance for optimizing kinetic promoter-regulated CO2 hydrate formation and continuous CO2 injection strategies in submarine sediments.
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高影响因子
Journal of Chromatography Open
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2025
·
IF 3.2
Zhixu Chen,Rongkai Gu,Mingming Zhao,Kefeng Linghu,Huanwei Fan,Tingting Zhang,Jincai Wang,Zhengjin Jiang
The N-terminal region of the polymerase subunit (PAN) is considered as the most promising target for the development of broad-spectrum antivirals, since it is highly conserved in structure and sequences among different influenza strains. In this study, a PAN based at-line nanofractionation (ANF) platform was applied to rapidly screen for PAN inhibitors from Rubus idaeus L. extract which presented good inhibitory effect on PAN with a half maximal inhibitory concentration (IC 50 ) value of 11 μg/mL. Eight PAN inhibitors were successfully screened out, comprising four organic acids and four flavones. In parallel, magnetic ligand fishing was used to isolate the PAN ligands from the extract, and finally four compounds were fished out and considered as PAN ligands (including avicularin, quercetin-3-O-rutinoside, ellagic acid and luteoloside) which were also identified by the ANF platform. Among them, ellagic acid and luteoloside displayed satisfactory in vitro inhibitory activity against PAN, with IC 50 values of 1.31 ± 0.33 and 6.23 ± 0.97 μM, respectively. The molecular docking and dynamic simulations revealed that ellagic acid and luteoloside bind to PAN in a distinctly different mode compared to baloxavir. These compounds formed direct interactions with catalytic pocket residues and adjacent amino acids in PAN, establishing hydrogen bonds and water-mediated bridges that modulated the protein's secondary structure and stability. The result from the study suggests that ellagic acid and luteoloside could serve as promising anti-influenza molecules. Furthermore, the ANF platform was proved effective for high-throughput screening of PAN inhibitors from complex herbal extracts, highlighting its significant potential for future anti-influenza drug development.
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高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2021
·
IF 10.588
Zhangdi Li,Mei Gou,Xuejie Yue,Qiong Tian,Dongya Yang,Fengxian Qiu,Tao Zhang
Fabrication of simple and efficient adsorbents is greatly vital to satisfy the requirements of removal of tellurium in wastewater treatment , yet remains challenging. Here, a facile and cost-effective strategy to develop ZIF-L coated self-crosslinking cellulose membrane (ZIF-L/SC membrane) for tellurium adsorption was presented. In-situ vertical growth of ZIF-L nanoplates with functional properties on membrane substrate is an available strategy, effectively remedying deficiency of pure nanosized sorbent in agglomeration problem and unhandy recovery. The SC membrane formed by strong hydrogen bonding among cellulose fibers is an excellent substrate, due to the favorable mechanical strength and abundant hydroxyl groups. The as-prepared ZIF-L/SC membrane shows advantageous morphology of large contact surface, fine thermal stability and eligible mechanical strength. The adsorption performance and possible mechanism of ZIF-L/SC membrane for Te (IV) were investigated by diverse characterization methods, showing admirable adsorption effect. Furthermore, the ZIF-L/SC membrane has excellent antibacterial properties, thus it is expected to deal with membrane fouling caused by microorganism breeding. Therefore, the bifunctional ZIF-L/SC membrane with excellent antibacterial activity is anticipated to be a promising candidate for efficient tellurium adsorbents, and simultaneously have potential in various fields in the future.
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高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2017
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IF 2.843
Ruoyun Li,Linbo Wu,Bo-Geng Li
In this work, PEG-mb-PPA (abbr.: PEGPA) copolymers were synthesized via chain extension/coupling of poly(ethylene glycol) (PEG) and poly(1,2-propylene adipate) (PPA) diols, and blends of commercial poly(l-lactide) (PLLA) and PEGPA were prepared via melt blending. The multiblock copolymers were characterized by 1H NMR and DSC, and the PLLA/PEGPA blends were characterized by DSC, SEM, tensile, and impact testing. Plasticization-dominant (elongation ∼250%), toughening-dominant (impact strength 33 kJ/m2), and plasticized-toughened (250%, 14 kJ/m2) blends were obtained by varying the composition and loading of PEGPA. The PLLA/PEGPA blends exhibited much more balanced mechanical properties in comparison with PEG-plasticized and PPA-toughened PLLAs, and the plasticization-dominant blends had superior performance stability in comparison with the PEG-plasticized PLLA. The SEM micrographs indicate that the immiscible PPA segment formed elongated microphases and acted as a toughener, whereas the miscible PEG segment acted as a plasticizer of PLLA and a compatibilizer of PPA. Such a synergistic effect of both segments was responsible for the balanced mechanical properties. The improved performance stability was attributed to the high molecular weight of the multiblock copolymers and the depressed crystallization of the PEG segment.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2022
·
IF 9.221
Xiao-Fan Wu,Qingmei Ge,Nan Jiang,Mao Liu,Hang Cong,Zhu Tao
Utilizing a novel concept of chiral amplification induced by host-guest interactions, a new macrocyclic compound , benzo[3]uril (BU[3]), was formed in a chiral microenvironment via the encapsulation of L -cysteine∙H + (L-Cys∙H), and the electrochemiluminescence properties of BU[3] were sensibilized with the formation of a supramolecular complex . Based on this principle, an ultra-sensitive chiral electrochemiluminescence sensor was constructed to recognize the enantiomer of penicillamine (PA). This sensor exhibited high selectivity and sensitivity for L -PA compared to other reported values, with a detection limit of 10 -12 mol·L -1 within a linear range of 10 -5 –10 -10 mol·L -1 , and no obvious electrochemiluminescence response to D -PA. The sensor presents high stability, good reproducibility, strong anti-interference ability, and acceptable recovery, which suggests an ability to quantitatively detect L -PA in an aqueous environment.
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高影响因子
RSC Advances
·
2022
·Vol. 12
·期 19
·11967-11973
·
IF 4.036
Yafeng Zhang,Huizhen Wang,Hu Yu,Xiaoxia Sun
Phenylalanine an essential aromatic amino acid for humans and animals, cannot be synthesized by humans and animals on their own. However, it synthesizes important neurotransmitters and hormones in the body and is involved in gluconeogenesis and lipid metabolism. Moreover, the two opposite configurations of phenylalanine have different activities. For example, L-phenylalanine is a biologically active optical isomer involved in crucial biological processes, the lack of which will lead to intellectual disability, while D-phenylalanine only acts as a chiral intermediate. In this research, an H8-BINOL chiral fluorescent sensor modified with 1,2,3-triazole was synthesized in high yield (95%) by nucleophilic substitution and click reaction. The chiral fluorescent sensor showed high enantioselectivity toward phenylalanine. L-Phenylalanine enhanced the fluorescence response of the probe significantly, while D-phenylalanine had no obvious fluorescence response change. The enantioselective fluorescence enhancement ratio [ef = (IL − I0)/(ID − I0), where I0 is the fluorescence of the sensor without amino acids] for the highest fluorescence intensity at 20.0 equivalents of amino acids was 104.48. In this way, the probe could be used to identify and differentiate different configurations of phenylalanine.
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高影响因子
Journal of Nano Research
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2017
·
IF 0.511
Wen Juan Dong,Ji Yan Han,Xin Wu,Li Fan,Wen Ting Liang
A novel near-infrared fluorescence quenching method has been developed for the determination of hydrogen peroxide based on N-acetyl-L-cysteine-capped gold nanoparticles (NAC-AuNPs) as a fluorescence probe. The prepared gold nanoparticles with the size of about 1.91 nm exhibited strong near-infrared fluorescence emission at 693 nm with excitation wavelength at 450 nm in aqueous solution. The fluorescence intensity of NAC-AuNPs was quenched dramatically by adding hydrogen peroxide. Therefore, it could be used to detect hydrogen peroxide based on the fluorescence quenching intensity was linear with the concentration of hydrogen peroxide. Under the optimal experimental conditions, the linear range and detection limit were 1.0×10-6 –3.0×10-2 mol/L and 1.0×10-7 mol/L, respectively. The possible quenching mechanism was investigated by time-resolved fluorescence spectroscopy. The proposed method was simple, sensitive and showed good repeatability and stability.
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INDUSTRIAL CROPS AND PRODUCTS
·
2019
·
IF 4.191
Xianchao Shang,Yuqing Dou,Yingjie Zhang,Jia-Neng Tan,Xinmin Liu,Zhongfeng Zhang
Natural deep eutectic solvents (DESs) have received increasing attention in recent years as emerging green solvents for efficient extraction of bioactive compounds from natural resources. In this study, we aimed to evaluate the potential and effectiveness of DESs with different polarities for extraction of isoflavones from chickpea sprouts. To this end, we examined 20 different DESs based on choline chloride, betaine, and l -proline as hydrogen bond acceptors in combination with different hydrogen bond donors (carboxylic acids, alcohols, sugars, and amine). Extraction efficiency was evaluated based on the extraction yields of four isoflavones (ononin, sissotrin, formononetin, and biochanin A), total flavonoid content, and anti-oxidant activity. On the basis of the results obtained, choline chloride-based DESs containing propylene glycol as a hydrogen bond donor (molar ratio of 1:1) with 30% (v/v) of water was the most effective at extracting isoflavone compounds from chickpea sprouts, compared to conventional solvents. Subsequently, in order to examine the factors contributing to optimal ultrasound-assisted extraction conditions, a Box-Behnken design paired with response surface methodology was implemented. DES water content and extraction temperature were accordingly found to have prominent effects on the extraction yields of isoflavones. Our results indicate that DESs can be used as suitable green solvents for extracting bioactive compounds from various biomaterials.
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