查找使用阿拉丁产品的科研文献

Reaction milling for scalable synthesis of N, P-codoped covalent organic polymers for metal-free bifunctional electrocatalysts

Xinxin Lin,Peng Peng,Jianing Guo,Zhonghua Xiang

This study exploits an effective mechanochemical process (termed as reaction milling) to conduct Schiff-based coupling reaction with melamine and terephthalaldehyde for the synthesis of covalent organic polymer (RM-COP) as the carbon skeleton and the derivative phosphorus doped material (RM-COP-PA). Comparing with the tradition solvothermal method with reaction time of 3 days under 120 °C, the newly developed reaction milling method significantly shorten the reaction time of the synthesis to 3 h under room temperature as well as bypassing the usage for hazardous solvents. The space-time yield of the developed reaction milling method for synthesis of the bifunctional electrocatalytic precursor reaches 189 kg m −3  day −1 . Significantly, the optimal products followed by further carbonization (RM-COP-PA-900) demonstrated excellent bifunctional electrocatalytic activities for an efficient ORR performance with similar commercialized Pt/C half-potential of 841 mV vs RHE as well as an IrO 2 -like OER activity with a potential of 1.69 V at 10 mA cm −2 in alkaline media, which is better than most metal-free bifunctional catalysts. Moreover, the obtained RM-COP-PA-900 exhibits much better durability and resistance to crossover effect even than the commercial 20 wt% Pt/C catalysts. Therefore, this work will open up a rapid, solvent-free and scalable approach for, but not limit to, highly efficient electrocatalysts.

Discovery of pentagalloylglucose as a dual GSTP1/ P-gp inhibitor uncovered by integrated computational and experimental approaches

Gaiqian Song,Ayixia Abudula,Moyisa Simayi,Hongning Liu,Hao Lin

Taxol remains a cornerstone therapy for non-small cell lung cancer, however, the development of acquired resistance continues to pose a significant clinical hurdle. Glutathione S-transferase P1 (GSTP1) and P-glycoprotein (P-gp) have been identified as key mediators of this multi-drug resistance phenotype. Consequently, the dual-target inhibition of these proteins represents a promising therapeutic strategy to circumvent chemoresistance. Here, pentagalloylglucose has been identified as a potential dual GSTP1/P-gp inhibitor through virtual screening. Molecular dynamics simulations validated the stable binding conformations of pentagalloylglucose with both target proteins. Furthermore, microscale thermophoresis and cellular thermal shift assays confirmed the direct binding interaction between pentagalloylglucose and GSTP1, while enzymatic assays demonstrated its potent inhibitory efficacy against the enzyme. Notably, treatment with pentagalloylglucose significantly enhanced the intracellular accumulation of Rhodamine 123, thereby indicating effective inhibition of P-gp mediated efflux. This effect culminated in a marked restoration of taxol sensitivity in A549/Taxol resistant cells. Additionally, pentagalloylglucose treatment inhibited cell metastasis in a concentration-dependent manner, accompanied by the down-regulation of epithelial-mesenchymal transition-related genes. Transcriptomic analysis further revealed that pentagalloylglucose modulates multiple signaling pathways implicated in cell proliferation and metastasis. Collectively, these findings establish pentagalloylglucose as a promising dual-target inhibitor for overcoming taxol resistance. The strategy of simultaneously targeting GSTP1 and P-gp offers a viable approach for the treatment of drug-resistant lung adenocarcinoma, providing a robust scientific foundation for future drug development and structural optimization.

A wireless sensor and energy harvesting system based on piezoelectric-electromagnetic synergy in P(VDF-TrFE) films

Yingjuan Yan\u003Csup\u003E1\u003C\u002Fsup\u003E,Weimin Xia\u003Csup\u003E1,\u003C\u002Fsup\u003E,Lu Wang\u003Csup\u003E2,\u003C\u002Fsup\u003E,Hong Pan\u003Csup\u003E1\u003C\u002Fsup\u003E,Xiaofang Zhang\u003Csup\u003E1\u003C\u002Fsup\u003E,Yinghui Wang\u003Csup\u003E1\u003C\u002Fsup\u003E,Xinru Wang\u003Csup\u003E1\u003C\u002Fsup\u003E,Ronghao Yang\u003Csup\u003E3\u003C\u002Fsup\u003E

With the rapid growth in the number of Internet of Things (IoT) nodes, developing self-powered systems that combine high energy conversion efficiency with stable power supply capabilities has become a key challenge. To address the issues of narrow operating bandwidth, poor environmental adaptability, and limited output power in traditional single-mechanism energy harvesters, this paper proposes a piezoelectric, electromagnetic hybrid energy harvester (PEEH) based on a bidirectional magnetic excitation mechanism. Guided by the finite element method, the rotor’s magnetic circuit structure was optimized to create a periodically alternating bidirectional “push-pull” magnetic excitation. This effectively suppresses asymmetric oscillations in the cantilever beam, enabling stable harmonic motion and achieving efficient electromechanical coupling with a β-phase-rich poly(vinylidene fluoride-trifluoroethylene) thin film. Thanks to this synergistic design, the PEEH achieves an output voltage of 112 V at a wind speed of 12 m/s, and its total power reaches 38.5 mW at 17 m/s. By further integrating an adaptive under-voltage lockout power management circuit, a fully self-powered wireless monitoring system was developed that enables periodic Bluetooth data transmission even under intermittent wind conditions. This study demonstrates that synergistically enhancing piezoelectric and electromagnetic energy conversion through magnetic circuit optimization can effectively improve wind energy utilization efficiency and system power supply stability, providing an efficient, stable, and grid-independent self-powered solution for next-generation wireless IoT nodes.

Copper-tailored d-p-π multi-orbital coupling in sulfurized polyaniline enables ultralong cycling aqueous sulfur batteries

Zhiwei Chen,Chaoyi Qiu,Zhichao Wang,Xiang Liu,Zihao Tao,Jiahe Geng,Xikun Zhang,Haoxiang Yu,Lei Yan,Peng Li,Liyuan Zhang,Ting-Feng Yi,Jie Shu,Bao-Lian Su

The practical application of sulfur-based batteries is significantly limited by sluggish reaction kinetics and structural collapse. Herein, a copper-modified sulfurized polyaniline (CuSPANI) cathode with distinctive d-p-π multi-orbital coupling is constructed through Cu heteroatom introduction. This coupling, arising from hybridization between Cu d orbitals and sulfurized polyaniline (SPANI) p/π orbitals, enables triple electronic modulation: reducing energy barriers to enhance kinetics, expanding electron delocalization to improve conductivity, and activating horizontal Cu d orbitals to strengthen structural stability. Consequently, the aqueous CuSPANI battery delivers a high reversible capacity of 834.75 mAh g s −1 at 3 C and exceptional cycling stability (61.2% capacity retention after 60,000 cycles at 15 C). Moreover, the designed flexible quasi-solid-state pouch cell achieves a 1.25 V output and maintains stable power under deformation, highlighting its potential for wearable energy storage. This work provides new insight into designing high-performance sulfurized polymers via orbital hybridization.

Separation of Hf(IV) and Zr(IV) using di(p-tert-octylphenyl) phosphate in sulfuric acid medium

Liu Xiaotong,Li Hui,Xu Chengjin,Peng Xiujing,Sun Guoxin,Cui Yu,Lu Ping

Efficient separation of nuclear-grade zirconium (Zr) and hafnium (Hf) remains a significant challenge in the nuclear industry. In this study, a novel extractant, di(p-tert-octylphenyl) phosphate (DTOPPA), was designed and synthesized. DTOPPA demonstrated preferential extraction of Hf over Zr in sulfuric acid media, surpassing the performance of conventional extractants such as D2EHPA and PC88A. Under optimized conditions, Hf(IV) extraction achieved 90.7% with a separation factor SF (Hf/Zr) of 13.4. Density functional theory (DFT) calculations and acid–base titration indicated enhanced dissociation of DTOPPA, attributed to the electron-withdrawing phenoxy group, which facilitates cation exchange. Slope analysis, saturation capacity measurements, and Fourier-transform infrared spectroscopy (FTIR) identified the extracted species as Zr(Hf)OA 2 ·2DTOPPA, involving cation exchange and P=O coordination. Selective stripping of Zr was accomplished using dilute sulfuric acid, while oxalic acid efficiently stripped Hf. A two-stage countercurrent extraction process yielded nuclear-grade Zr with stable organic phase recycling. This novel extractant provides an environmentally friendly and efficient method for Zr/Hf separation with significant potential for industrial application.

Regulating smoke precursors and enhancing durability of flexible polyurethane foam via reactive hyperbranched P-N flame retardant

Deyu Liu,Lirui Qiao,Jialei Kang,Ying Lu,Xuanle Lv,Yuhan Zhang,Feng Zhang,Yapeng Wang,Zheng Wang,Dan Meng

A fire safety FPUF was designed by using only 8 wt.% reactive flame retardant. • Resultant FPUF showed excellent smoke suppression, reducing TSP (−79.3%) and smoke density (−83.1%). • 42.7% and 50.7% reductions in pHRR and THR of FPUF-HTMP8 were achieved. • A smoke precursor regulation mechanism was experimentally verified. • The mechanical properties and fire safety for FPUF-HTMP8 were effectively maintained. Flexible polyurethane foam (FPUF) is highly flammable and releases lethal toxic smoke during combustion, primarily derived from isocyanate-containing structures. Furthermore, adding flame retardants inevitably leads to migration and failure issues. This study addressed the neglect of smoke-suppression mechanisms by synthesizing a phosphorus-nitrogen reactive flame retardant (HTMP). HTMP chemically incorporates into the polymer network via its multi-reactive sites, actively regulating thermal degradation pathways. Results demonstrated that 8 wt.% HTMP modified FPUF achieved a limiting oxygen index (LOI) of 24.1%, passed the HF-1 rating, and exhibited a 53.3% reduction in total heat release (THR). Notably, total smoke production (TSP) and smoke density decreased by 79.3% and 83.1%, respectively. It was demonstrated that HTMP regulated the reaction pathway of isocyanates produced by thermal decomposition of polyurethane through its hydroxyl groups and the amine structures generated by degradation, inducing cross-linking and cyclization reactions, and suppressing the production of smoke precursors from the source, inhibiting toxic volatiles (HCN). In addition, due to terminal hydroxyl groups, HTMP entered the FPUF network, endowing the material with excellent long-term service stability and improved mechanical properties. This research provides new insights for designing fire safety FPUF samples with low smoke release materials from a reaction pathway perspective.

Green synthesis of defect-regulated Zr-MOFs for rapid capture of p-arsanilic acid from aqueous solutions

Huifang Zhao,Chunhong Liu,Wang Liao,Yingjie Zhao

Green synthesis of defective Zr‑MOFs employed mercaptoacetic acid (MAA) as a modulator. • MAA dosage regulated framework defects, pore structure, and surface properties. • The optimized DPM-2 achieves a high adsorption capacity of 356.4 mg·g⁻¹ with equilibrium reached within 60 min. • Electrostatic, chemical, and hydrogen‑bonding interactions collectively enhanced p-ASA adsorption. Defect modulation is an effective strategy for optimizing the pore architecture and active-site accessibility of metal-organic frameworks (MOFs). Herein, a series of defective Zr-MOFs was synthesized in an aqueous medium using mercaptoacetic acid (MAA) as an acid modulator and is denoted as DPM-X (DUT-67(PZDC)-MAA-X, where X denotes the volume of MAA added). Structural characterization revealed that the MAA dosage played a key role in regulating framework defect formation, thereby altering the pore characteristics and surface chemical properties of the synthesized MOFs. Benefiting from abundant adsorption sites and a special pore structure, DPM-2 exhibited a high uptake of 356.4 mg·g −1 for p-ASA and reached equilibrium within only 60 min. Moreover, the material showed remarkable resistance to interference from coexisting ions and retained excellent regeneration performance during repeated use. The adsorption mechanism involves the synergistic action of electrostatic attraction, chemical bonding, and hydrogen-bonding interactions. The proposed green defect-engineering strategy provides an effective route to regulate the structural properties of Zr-MOFs, offering a practical approach to tailoring pore structure, surface chemistry, and adsorption performance. Download: Download high-res image (162KB) Download: Download full-size image Mercaptoacetic acid-modulated defect-engineered Zr-MOFs for rapid and high-capacity p-arsanilic acid removal

A Formaldehyde-Free, Soy Protein-Based Adhesive with P-N-Si Synergistic Flame Retardancy for Plywood Application

Han Yang,Nicolas Gascoin,Liping Jiang,Xiaofeng Zhu,Xiang Huang,Khaled Chetehouna,Ruihua Guo

To overcome the flammability and formaldehyde-emission problems associated with plywood, a novel soy protein-based intumescent flame-retardant adhesive with phosphorus–nitrogen–silicon (P-N-Si) synergism (C@Si@APP) was developed in this study. C@Si@APP was initially prepared by coating silane-modified ammonium polyphosphate with collagen. Subsequently, C@Si@APP was combined with lignin and adenine and incorporated into a soy protein, collagen, and isocyanate (MDI)-based adhesive matrix to fabricate a flame-retardant adhesive for eucalyptus plywood. Cone calorimeter (CONE) analysis demonstrated that the flame-retardant plywood bonded with SPI/C/MDI/C@SiAPP18 achieved the most effective flame-retardant and smoke-suppression performance, and the peak heat release rate, total heat release, and total smoke production were reduced by 23.5%, 20.7%, and 43.9%, respectively, and the release rates of CO and CO2were also effectively suppressed. Mechanistic analysis indicated that the enhanced flame retardancy was mainly governed by a condensed-phase mechanism, in which phosphorylation and siloxane crosslinking promoted the formation of a compact and thermally stable char layer that protected the underlying material, whereas a gas-phase contribution involving the dilution of flammable volatiles by non-combustible gases (NH3, H2O, and CO2) and possible radical scavenging by phosphorus-containing species is proposed as a plausible complementary pathway inferred from the TGA-FTIR results and the previous literature.

Assessment of p-Xylene Migration Behaviour in Unsaturated Soil Systems: A 3-D Sand Flow Chamber Study

The influence of soil water content and contaminant injection pressure on the migration behaviour of p-Xylene (one of the organic pollutants in Benzene Toluene Ethylbenzene & Xylene) is investigated in the unsaturated zone using the controlled laboratory sandbox experiments. The results show that, at equivalent migration distances, higher soil water content leads to longer migration durations and reduces transport velocities, whereas greater injection pressure promotes faster contaminant movement. These findings highlight the governing role of water saturation in the water–oil–gas three-phase system, in which increased water content decreases the relative permeability of the oil phase and retards capillary-driven BTEX transport. Unlike many previous studies in which contaminants commonly migrate downward toward the groundwater table, the BTEX in this study did not reach the water table and exhibited partial upward migration. Overall, the results provide experimental-scale insight into key mechanisms governing BTEX transport in unsaturated sandy media and serve as a reference for improving predictions of contaminant fate and migration pathways in field settings.

Multi-wavelength photodetector based on SnS2/Gr/SnS p-g-n trilayers with high responsivity and detectivity

Shiao Feng,Zirui Huang,Xiyu Jia,Mengjiao Dong,Chun Sun,Yonghui Zhang,Chao Fan

A SnS 2 /graphene/SnS trilayer vdW heterojunction was constructed. • Graphene promotes charge transport and suppresses dark current. • The device achieves 5656.3 A W −1 responsivity at 405 nm. • Broadband detection from 405 to 850 nm is demonstrated. • Self-powered operation and imaging applications are achieved. Two-dimensional (2D) semiconductors are promising materials for broadband photodetection, benefiting from their favorable light–matter interaction and electrical properties. As an n-type layered semiconductor, SnS 2 is suitable for photodetection because carriers can move efficiently in it and incident light can be effectively absorbed, making it suitable for photodetection applications. In this work, SnS 2 /graphene/SnS (SnS 2 /Gr/SnS) trilayer van der Waals heterojunctions and corresponding photodetectors were fabricated and investigated. Owing to the graphene interlayer, which serves as both a carrier transport layer and a barrier layer, The detector responds to light over a wide spectral range, covering both the near-ultraviolet (NUV) and near-infrared (NIR) regions. Under 405-nm irradiation, the photodetector reaches an R value of 5656.3 A·W −1 and a D ⁎ value of 3.33 × 10 13 Jones. When the wavelength is extended to 850 nm, the responsivity remains 574.2 A·W −1 . The device also shows clear self-powered behavior, outperforming the conventional SnS 2 /SnS bilayer heterojunction photodetector. These results offer an effective strategy for improving SnS 2 -based broadband photodetectors and promotes their potential applications in optical communication and single-pixel imaging. Download: Download high-res image (225KB) Download: Download full-size image

N,S,P-Modified Carbon Dot Nanoadditives for High-Load Antiwear Protection for Steel-to-Steel Contact

Xia Junkun,He Zhongyi,Lei Juanhong,Long Qiyang,Xiong Liping,Li Lili,Liu Feng,Ouyang Laizhao,Zeng Xiangqiong

Carbon dots are attractive lubricant nanoadditives because their nanoscale size and tunable surface chemistry allow them to interact with confined friction interfaces. However, achieving effective antiwear protection under high contact loads requires surface structures that can couple physical filling with interfacial film formation. Here, N, S, and P-modified carbon dots (NSP-CDs) were prepared from glucose-derived carbon using taurine and phytic acid as heteroatom sources. The resulting NSP-CDs had an average size of about 2.5 nm and exhibited abundant oxygen-, nitrogen-, sulfur-, and phosphorus-containing functional groups. When used as nanoadditives, 0.3 wt % NSP-CDs markedly improved the antiwear performance of steel-to-steel contacts. At 392 N and 1400 rpm, the average wear scar diameter decreased by 47.5% compared with the base oil, while the wear volume and apparent wear rate both decreased by about 92.4%. Wear scar morphology, elemental mapping, and X-ray photoelectron spectroscopy showed that NSP-CDs formed a composite protective film containing a carbonaceous adsorption layer, iron oxides/hydroxides, P–O/Fe–O–P-related phosphates, and oxidized sulfur species. The antiwear effect is attributed to the combined action of nanoparticle filling, rolling-polishing, and N, S, and P-assisted interfacial film formation. These results suggest that multielement surface modification is an effective strategy for designing carbon dot nanoadditives for high-load antiwear lubrication.

Built-in Fields at RuO2/TiO2 p−n Interfaces Promote Water Dissociation and Durable Acidic Oxygen Evolution

Jinzeng Guo,Penghao Li,Diandian lv,Wenxiang Zhu,Qi Shao,Zhenhui Kang,Mingwang Shao,Fan Liao

Developing durable and active catalysts for the acidic oxygen evolution reaction (OER) remains a central challenge for water electrolysis. Here, we demonstrate that constructing supported p−n junctions provides an effective strategy to simultaneously couple interfacial water activation with active-site stabilization. RuO2 nanoparticles immobilized on oxygen vacancy-rich TiO2 nanoribbons (RuO2/TiO2NRs) form a robust p−n heterojunction whose built-in field directs charge separation and tunes interfacial energetics. TiO2 acts as a water-activation co-catalyst, facilitating H2O dissociation at the junction, while structural confinement and charge redistribution suppress Ru over-oxidation and dissolution. A transient potential scanning technique directly visualizes the interfacial charge storage and release behaviors, providing dynamic evidence for the built-in electric field of the p−n junction in regulating charge separation and water-dissociation kinetics. Theoretical calculations reveal electron enrichment on Ru, weakened *OH/*O adsorption, and a reduced barrier for the potential-determining *O → *OOH step, while differential electrochemical mass spectrometry confirms an adsorbate-evolution mechanism without lattice oxygen participation. Consequently, RuO2/TiO2NRs deliver an overpotential of 192 mV at 10 mA cm−2 in 0.5 M H2SO4 and sustain a ∼650 h durability. This heterojunction-guided loading strategy unifies activity and acid durability by co-engineering charge transfer and water activation at oxide/oxide interfaces.