CARBOHYDRATE POLYMERS
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2026
·
IF 13.2
Qingchen Cui,Linrong Yu,Jiahe Miao,Yanjun Wei,ShanShan Du,Xianggen Wu
Curdlan (CUR)-based hydrogels have shown promise for wound healing but suffer from poor flexibility, high brittleness, and limited drug-loading capacity. To overcome these limitations, a curdlan-based complementary hydrogel (CM Gel) was developed by integrating CUR with mangiferin (MF), a polyphenol capable of self-assembly. Non-covalent interactions between CUR and MF led to a stable and flexible network with improved mechanical properties and gelation under mildly acidic pH conditions (pH ∼6.5), which aligns with skin wound conditions. Furthermore, the hydrogel was loaded with dihydromyricetin (DMY), a natural antibacterial agent, using a solvent-free one-pot pH/heating-driven process to fabricate the enhanced comprehensive hydrogel properties D@CM Gel. Multispectral analysis suggested that MF, CUR, and DMY were transformed from the crystalline state to the amorphous state. In vitro studies confirmed its potent antibacterial activity against S. aureus and E. coli , strong antioxidant capacity, and effective biofilm inhibition capacity. In an S. aureus -infected full-thickness wound model, D@CM Gel significantly accelerated wound closure, reduced inflammation (TNF-α, IL-6), promoted collagen deposition and angiogenesis (VEGF, CD31, α-SMA), and outperformed commercial hydrogel dressings with excellent biocompatibility. These findings suggest that D@CM Gel is a promising and easily fabricated wound dressing with synergistic therapeutic functions for treating infected skin wounds.
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高影响因子
FOOD CONTROL
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2026
·
IF 7
Yangchun Ge,Zhuochao Shen,Yuying Xie,Jiangkuan Tang,Haohua Zhang,Yupeng Qiu,Xuqiang Peng,Lanlan Zhai,Zhongyu Li
This study reports the rational design and fabrication of an intelligent, self-healing hydrogel tailored for fruit preservation via the dynamic cross-linking of chitosan (CS) with a synthesized phenylboronic acid-based crosslinker (DMSA-PBA). The strategic introduction of dynamic boronate ester bonds as the key crosslinking nodes is pivotal, granting the material not only rapid gelation (<60 s) and autonomous self-healing capabilities but also dual responsiveness to pH and reactive oxygen species (ROS). The resulting hydrogel network exhibits a suite of exceptional properties: superior mechanical robustness, a high swelling ratio (∼1000%), and outstanding water vapor barrier performance. Furthermore, the inherent synergistic antibacterial activity, stemming from the chitosan and the DMSA-PBA components, was confirmed. When evaluated as a protective coating on mangoes, this multifunctional hydrogel significantly delayed quality deterioration during ambient storage, effectively reducing weight loss and decay incidence while maintaining firmness and acidity. This work underscores the immense potential of dynamic covalent chemistry in designing advanced coatings for sustainable food preservation, presenting a feasible and eco-friendly strategy grounded in a well-defined material design.
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JOURNAL OF MEMBRANE SCIENCE
·
2026
·
IF 8.8
Min Fang,Jiaxue Chen,Qiuyu Zheng,Xiaoshuang Yin,Wenzhong Yang,Hui Xu
In response to the increasingly complex composition of industrial oily wastewater, the design of multifunctional separation materials capable of achieving phase-selective separation and efficient demulsification has become a major research focus. This study employed electrospinning to fabricate a novel nanofibrous membrane. The membrane was prepared from a blend containing the rationally designed, pH-responsive triblock copolymer poly(4-vinylpyridine)- block -poly(2-hydroxyethyl methacrylate)- block -poly( tert -butyl methacrylate) (P4VP- b -PHEMA- b -P t BMA) and polyacrylonitrile (PAN). The resulting membrane exhibits a unique bidirectional separation capability, allowing for the controlled separation of either light or heavy oil-water mixtures by simply adjusting the pH of the aqueous environment. It achieves a maximum oil-phase flux of up to 12,800 L/(m 2 ·h) with 98.8% separation efficiency, while maintaining a stable water-phase flux around 8500 L/(m 2 ·h) and efficiencies above 99%. Furthermore, the membrane was capable of effectively disrupting and separating stable water-in-oil and oil-in-water emulsions. Across repeated tests with diverse oil-water systems, the membrane consistently demonstrated high flux, high separation efficiency, and excellent cycling stability, highlighting its great potential in the design of intelligent separation materials and the treatment of complex wastewater.
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
·
IF 5.4
Yuxin Tang,Xinyi Yang,Lingyu Zeng,Bili Tan,Fei Qi,Bo Feng,Liang Wang,Guangbo Che
Precise atomic-scale interface engineering across the entire pH range remains a formidable challenge for photocatalytic H 2 evolution. Herein, hexamethylenetetramine (HMT) is introduced as a bifunctional surface modifier that spontaneously constructs Pd-N coordination bridges on g-C 3 N 4 . The interfacial Pd-N bonds collectively down-shift the N-p-band center away from the Fermi level, break intrinsic surface charge symmetry of C/N atoms, and fully expose the originally buried N active sites, thereby steering the hydrogen adsorption free energy (|ΔG H* |) toward thermoneutral. Simultaneously, the Pd-N bond confines Pd cluster growth to ∼5 nm, doubling specific surface area and enriching edge active sites that serve as primary proton reduction centers. Transient photoelectric voltage results reveal that the Pd-N electron transfer channel shortens the carrier transfer path and prolongs photoelectron lifetime, enabling quantitative electron delivery under acidic, neutral, and alkaline environments. As a result, the Pd-CN-HMT sample presents an efficient H 2 evolution rate across the entire pH window. This work advances the field by providing a versatile ligand-based strategy to precisely tailor the interfacial electronic structure via strong chemical bonding, offering a distinct and scalable solution for constructing high-performance pH-universal photocatalysts.
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产品关联
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高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2026
·
IF 4.8
Dongyan Hu,Jiao Guan,Jiaming Luo,Liushuang Zhang,Zhijuan Bao
RGB probe monitors lysosomal pH in real time. • Biocompatible design suits live-cell imaging. • High sensitivity tracks subtle pH fluctuations. • Enables visualization of lysosome-related pathological processes. Lysosomal pH is tightly linked to diverse cellular physiological and pathological processes, and real-time monitoring of its dynamic shifts is critical for uncovering underlying disease mechanisms. Herein, we developed a new lysosome-targeted pH fluorescent probe RGB with facile synthesis, low cytotoxicity, favorable biocompatibility and efficient cell membrane permeability. Its fluorescence emission intensity exhibits a well-defined linear correlation with environmental pH, enabling rapid, sensitive and quantitative detection of subtle pH changes at the single-lysosome level. RGB functions via a pH-triggered spirolactam ring-opening ICT fluorescence turn-on mechanism, with a measured pKa value of 4.12. Confocal fluorescence imaging results verify that RGB can evaluate oxidative stress-induced cellular damage and dynamically visualize autophagy in live tumor cells. As a robust molecular imaging reagent, RGB holds great promise for subcellular pH detection and basic mechanistic exploration of lysosome-associated disorders. The RGB fluorescent probe provides a simple, biocompatible tool for sensitive real-time monitoring of lysosomal pH. It allows visualization of key cellular events and offers valuable insights for biomedical research on lysosome-related processes. Download: Download high-res image (154KB) Download: Download full-size image
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MICROCHEMICAL JOURNAL
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2026
·
IF 5.2
Rui Cheng,Hongan Zhang,Ziqi He,Xueting Luo,Wanju Zhang,Ziqiang Xu,Minsong Lin
Myricetin-derived carbon dots enable ratio-metric pH sensing with pH from 7.2 to 9.6. • Hydrazone structures confer highly sensitive and selective Al 3+ recognition. • Confocal imaging validates dual-function intracellular pH and Al 3+ monitoring. Sensitive analysis of intracellular pH and Al 3+ is essential for biological and environmental accessment. And traditional fluorescent nanomaterials often contain heavy metal components, whereas carbon dots (CDs) are metal-free with excellent biocompatibility, making them attractive candidates for probe construction. However, most CDs-based fluorescent probes have been developed empirically, with rational design strategies remaining relatively limited. Therefore, hydrazone functionalized carbon dots (N 2 H 4 @CDs) are fabricated by combining natural myricetin precursor with hydrazine-assisted post-functionalization strategy, establishing a structure-guided design that enables both ratio-metric pH sensing and selective Al 3+ analysis. Notably, N 2 H 4 @CDs showed dual emissions at 495 and 570 nm, with the peak at 570 nm increasing under higher pH. This ratio-metric response enabled accurate self-calibrated analyzing, showing a great linear correlation between the ratio I 495 / I 570 and pH from 7.2 to 9.6. As for Al 3+ analysis, fluorescence spectra show a pronounced enhancement of the emission intensity at 495 nm upon addition of Al 3+ , reflecting specific coordination with surface functional groups. The N 2 H 4 @CDs platform enable sensitive analysis of Al 3+ , with a linear range of 2–18 μmol/L and a detection limit of 0.125 μmol/L (3.37 μg/L). The spiked recovery experiments in lake water yielded satisfactory results, indicating its potential application in environmental exposure analysis. Confocal imaging in L929 fibroblasts confirmed that N 2 H 4 @CDs enable imaging of intracellular pH and Al 3+ . This strategy propses a rational hydrazone engineering strategy to realize ratiometric pH imaging as well as selective Al 3+ sensing. Download: Download high-res image (100KB) Download: Download full-size image
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高影响因子
Gels
·
2026
·Vol. 12
·期 10
·873
·
IF 6.4
Xueqiao Wang,Jing Wang,Wenxuan Wang,Ruimeng Liu,Yimin Shi,Daxin Liang
Efficient seawater lithium harvesting requires adsorbents combining high selectivity with scalable, low-energy fabrication. Although H2TiO3lithium-ion sieves (HTO-LIS) exhibit exceptional Li+selectivity, their deployment is hindered by strict alkaline requirements and reliance on energy-intensive shaping processes such as freeze-drying. Herein, we report a cellulose nanofibril (CNF) composite aerogel addressing both challenges simultaneously. Ammonium phytate (AP), a bio-derived polyphosphate, serves a dual function: as a green crosslinker for CNF and as an in situ alkalinity generator, creating a localized alkaline microenvironment around immobilized HTO nanoparticles that enables efficient topotactic H+/Li+exchange at seawater-relevant pH 8 without requiring strongly alkaline bulk conditions. Crucially, the AP-crosslinked CNF skeleton withstands capillary forces during ambient-pressure drying, preserving a hierarchical macroporous network without freeze-drying. The resulting AP-CNF@HTO monolith achieves a Li+capacity of 19.08 mg g−1at pH 8, a 128.9% enhancement over pristine HTO, with excellent selectivity against competing ions in real seawater and 88.3% capacity retention after ten cycles. This work demonstrates that rational bio-based crosslinker selection can concurrently solve the alkaline microenvironment and ambient-drying challenges of HTO-LIS composites, offering an ambient-pressure-drying route with reduced reliance on energy-intensive freeze-drying for seawater lithium enrichment.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2026
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IF 8.7
Ting Wu,Qiwei Wang,Sihan Zhou,Hecheng Chen,Libing Zhang
pH-tunable, reversible bidirectional bending in the electro-responsive oppositely charged polyelectrolyte Janus hydrogel. • EHD printing-in-situ photopolymerization strategy resolves CS/SA hydrogel performance bottlenecks. • Excellent mechanics (808.9% strain) and high ionic conductivity (13.81 × 10 −3 S/cm) integrated in the hydrogel. • Practical devices (soft gripper, biomimetic flower) validate broad applications in soft robotics. Polyelectrolyte hydrogels are ideal for soft actuators, but conventional chitosan/sodium alginate (CS/SA) ionic hydrogels face a critical trade-off among flexibility, ionic content, and actuation speed, hindering their practical applications. Herein, dimethylaminoethyl methacrylate (DMAEMA) and sodium acrylate (AAS) were used to modify CS-based polycationic and SA-based polyanionic networks, respectively. A Janus polyelectrolyte hydrogel (PCDM/PSSM) with seamless interface was fabricated via one-pot synthesis, electrohydrodynamic (EHD) printing, and in-situ photopolymerization. Microstructural characterization verified successful monomer grafting, amorphous/low-crystallinity networks, and robust interlocked interfaces. The hydrogel exhibited superior mechanical properties (PSSM achieving a tensile stress of 78.6 kPa and a strain of 775.6%, and PCDM achieving a tensile stress of 52.2 kPa and a strain of 808.9%, respectively), high ionic conductivity (13.81 × 10 −3 S/cm for PSSM), and efficient electro-actuation (155° bending at 10 V). Its core advantage is pH-programmable reversible bidirectional bending: −145° toward the polyanionic layer at pH = 2 and + 151° toward the polycationic layer at pH ≥ 7, originating from pH-regulated asymmetric swelling of protonated/deprotonated functional groups and enhanced by electric-field-induced ion migration. Demonstrated applications included an underwater soft gripper for fragile object manipulation and a biomimetic flower for pH-responsive petal closure. This work resolves the longstanding trade-off of CS/SA hydrogels and provides a scalable strategy for high-performance stimuli-responsive soft actuators, promising broad use in soft robotics, bioinspired systems, and biomedical engineering.
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DOI
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2026
·
IF 6.7
Mengyuan Pu,Yuerong Chen,Yijiang Shang,Xupeng Wang,Changqing Fang
Traditional pH-responsive hydrogels have garnered significant interest for smart sensing applications. However, their widespread adoption is often hampered by a compromise between mechanical robustness and rapid fabrication, as well as limited functional versatility. Herein, we present a multifunctional hydrogel with broadly tunable mechanical properties, dual-mode (visual and resistive) pH sensing and unique asymmetric adhesion. The hydrogel network can be rapidly fabricated within 1 min via a straightforward UV photopolymerization. By modulating the photoinitiator concentration, the crosslinking density and polymer chain length can be systematically adjusted, thereby regulating the glass transition temperature ( T g ) and enabling hydrogels with a stiffness variation spanning three orders of magnitude in storage modulus. Furthermore, a flexible resistive sensor based on a copolymer network of hydroxyethyl methacrylate, acrylic acid and conductive sulfopropyl methacrylate salt was developed. Within a test range of pH 4.0–8.0, the sensor exhibited stable real-time response characteristics and an ultrafast response time of 100 ms. Combined with smartphone-based colorimetric quantification via an integrated pH-sensitive dye, this hydrogel platform offers comprehensive dual-channel monitoring. This work provides a novel design strategy for next-generation smart materials, showcasing great potential in wearable sensors, soft robotics and intelligent biomedical devices.
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高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2026
·
IF 7.1
Yilin Han,Xianxuan Li,Lingwan Zhang,Kai Zhong,Yanping Wu,Hong Gao
The development of active packaging with sustained antimicrobial and antioxidant functions is crucial for extending the shelf life of highly perishable fruits. In this study, we developed a novel composite film by incorporating dihydromyricetin (DMY)-loaded zeolitic imidazolate framework-8 (ZIF-8) nanoparticles into a chitosan (CS) matrix. Scanning electron microscopy (SEM) confirmed the good compatibility between ZIF-8@DMY and the chitosan matrix at optimal loadings (2.5–15wt%). Importantly, the incorporation of ZIF-8@DMY significantly enhanced the mechanical properties of the composite films, increasing tensile strength by approximately 4.8-fold (from 1.77 to 8.50 MPa). Concurrently, critical physical properties including water vapor permeability, hydrophilicity and UV-vis transmittance were also enhanced. The composite films exhibited intelligent pH-responsive release of DMY. Furthermore, the ZIF-8@DMY/CS films exhibited potent in vitro antibacterial activity against Escherichia coli and Staphylococcus aureus , with the 5% ZIF-8@DMY/CS film reducing E. coli counts by 5.38 log CFU/mL. In the grape preservation test, the 5% ZIF-8@DMY/CS film effectively mitigated weight loss and retained higher levels of total soluble solids (TSS) and ascorbic acid (V C ) over10 days of cold storage. These findings highlight that ZIF-8@DMY/CS composite films are a promising smart active packaging material for preserving the postharvest quality of fresh produce.
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高影响因子
POLYMER
·
2026
·
IF 5.1
Yuanhang Xiao,Changqi Chen,Jiaxin Chen,Chunhua Wang,Wei Lin
Amphoteric compounds as metal-free alternatives offer a promising pathway to address the environmental and health challenges associated with chromium salts, as well as the charge mismatch between organic tanned leather and anionic dyes. Herein, we design a multifunctional amphoteric triazine derivative (EDTB) through synergistic modulation of reactivity, molecular size, and surface charge, which features multiple active chlorines, pH-responsive aggregation behavior, and high isoelectric point to achieve efficient tanning and enhanced dyeing performance. EDTB can assemble to form micron-scale aggregates through electrostatic interactions, which enables uniform diffusion and multipoint covalent crosslinking within collagen matrix, while regulates the interfacial electrostatics of fiber to improve the absorption and fixation of dyes. The EDTB-tanned leather exhibits superior hydrothermal stability ( T s ∼82 °C), mechanical strength (tensile strength >24 MPa, tear strength >66 N/mm), and color depth (K/S value of 15.0) compared to leather tanned with commercial tanning agent (i.e., F-90). Moreover, the pickling- and basifying-free EDTB tanning system demonstrates reducing chloride discharge, improving wastewater biodegradability, and lowering the carbon footprint by over 40% relative to chrome tanning. This work establishes a versatile amphoteric triazine-based tanning strategy integrating high tanning efficiency and dyeing assistance, offering a practical and scalable solution for advancing sustainable leather manufacturing.
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高影响因子
PROGRESS IN ORGANIC COATINGS
·
2026
·
IF 7.9
Han Yin,Haiyan Li,Feng Guo,Wenhao Bo,Yue Li,Hongxin Luo
Achieving durable corrosion protection in epoxy coatings remains challenging because barrier degradation, chloride penetration, and insufficient inhibitor utilization occur simultaneously during long-term exposure. Herein, mesoporous silica nanocapsules (MSN-BC) co-encapsulating benzotriazole (BTA) and cetyltrimethylammonium bromide (CTAB) were synthesized via a one-pot method, where CTAB functioned dually as a pore-forming agent and a corrosion inhibitor. Magnesium‑aluminum layered double hydroxide (LDH) nanosheets were subsequently grown in situ on the nanocapsule surfaces. The nanocapsules showed pH-responsive inhibitor release and strong Cl − adsorption. A key finding from electrochemical impedance spectroscopy (EIS) was that the dual-inhibitor (MSN-BC) system exhibited superior corrosion protection compared with nanocapsules containing only CTAB or BTA, indicating an enhanced combined inhibition effect. This interpretation was further supported by density functional theory (DFT) calculations, which suggested favorable co-adsorption of BTA and CTAB on the Q235 steel surface. At an optimal loading of 1 wt% in epoxy, MSN-BC-LDH dispersed uniformly, reduced coating porosity, and improved barrier performance. After 60 days in 3.5 wt% NaCl solution, the coating maintained an impedance modulus of 8.2 × 10 8 Ω·cm 2 at 0.01 Hz, one order of magnitude higher than pure epoxy. The enhanced protection arises from coating densification, LDH-enabled Cl − trapping, and synergistic dual-inhibitor action.
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高影响因子
危险品化学品经营许可证（带存储）