SEPARATION AND PURIFICATION TECHNOLOGY
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2026
·
IF 9.1
Heng Li,Rongxin Guo,Chang Liu,Dexin Chen,Junjie Yang,Qiwei Wang,Peng Zhang
A TA-PEI “molecular bridge” strategy was devised for robust in-situ growth of ZIF-8 on PES membranes. • The composite membrane exhibited 175.48 L·m −2 ·h −1 flux and 98.29% oil rejection. • The membrane exhibited outstanding stability in highly alkaline (pH 12) environments. • Mechanical strength was significantly improved due to ZIF-8 reinforcement and crosslinking synergy. The treatment of highly alkaline, surfactant-stabilized oily wastewater from electroplating pretreatment poses a significant challenge for membrane technology. Conventional polyethersulfone (PES) ultrafiltration membranes suffer from severe fouling and chemical degradation under such harsh conditions. To address these dual limitations of performance and stability, this study developed a “blending-in-situ growth” strategy to fabricate a ZIF-8/TA-PEI/PES composite membranes. The TA-PEI interlayer acts as a molecular bridge, enabling uniform and robust anchoring of the ZIF-8 coating. The optimized membrane exhibited a pure water flux of 175.48 L·m −2 ·h −1 (≈4.5× that of pristine PES) and a high flux recovery rate of 75.86%. For surfactant-stabilized oil-in-water emulsions, it achieved 98.29% rejection, maintaining 96.54% efficiency over 10 cycles. Crucially, it demonstrated exceptional alkali resistance, retaining 92.17% rejection after 72 h at pH 12, alongside a tripled tensile strength (3.01 MPa). This work provides a durable and high-performance membrane solution engineered specifically for the demanding separation of complex industrial wastewater. Download: Download high-res image (249KB) Download: Download full-size image
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Surfaces and Interfaces
·
2026
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IF 6
Anh-Tuan Pham,Dang Thi Hanh Trang,Ngo Thi Loan,Nguyen Thai Huy,Nguyen Ha Anh,Ta Ngoc Bach,Quan-Doan Mai,Anh-Tuan Le
Styrene is one of the most important volatile organic compounds (VOCs) used extensively in polymer and composite manufacturing, where occupational exposure occurs predominantly through inhalation of its vapor. Although surface-enhanced Raman spectroscpoy (SERS) offers exceptional sensitivity for molecular analysis, its application to vapor-phase detection remains challenging because volatile molecules are difficult to efficiently accumulate at plasmonically active sites. Consequently, conventional styrene vapor analysis generally relies on multistep workflows involving vapor sampling and analyte desorption prior to analysis. Herein, we report a flexible Cellulose/ZIF-8/Ag SERS chip combined with a simple attach-and-capture strategy for direct solvent-free detection of styrene vapor. By attaching the SERS sensing chip to the inner surface of a vial cap, vapor sampling and SERS detection were integrated into a single workflow without additional sample pretreatment. The developed SERS platform achieved a detection limit of 240 mg/m 3 , below current occupational exposure limits for styrene, together with excellent analytical reliability (RSDs of 1.89% within a single chip and 5.29% between independently fabricated chips), good selectivity for styrene, stable performance under high relative humidity, robust SERS activity after repeated mechanical deformation, and outstanding post-sampling signal stability. By separating passive vapor accumulation from subsequent spectroscopic analysis, the attach-and-capture configuration enables the chip to be deployed in advance and retrieved for rapid on-demand SERS readout, offering operational flexibility beyond conventional multistep sampling workflows. These findings establish the proposed attach-and-capture strategy as a practical analytical workflow for integrating vapor sampling and SERS detection into a single solvent-free operation for rapid occupational monitoring of styrene vapor. Download: Download high-res image (171KB) Download: Download full-size image
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Materials Today Communications
·
2025
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IF 4.5
Fangyu Liu,Zichen Liang,Yi Zhang,Siyu Qin,Siqi Zhang,Tao Zhang,Bo Li,Xiaoling Liao,Xiaoming Li,Shuang Yang
Rapamycin (RAPA) is widely used in biomedical applications due to its antitumor, autoimmune disease and neuroprotective effects. However, direct administration of RAPA may lead to side effects such as excessive suppression of the immune system, severe infections and increased risk of tumors. Zeolitic imidazolate framework-8 (ZIF-8) is one of the most promising MOFs that shows great potential in the field of drug delivery. In this study, we successfully prepared nano-ZIF-8 particles of uniform size and monodispersity by optimizing the reaction time, stirring time, and reactant concentration. ZIF-8 was used as a carrier loaded with RAPA (ZIF-8@RAPA), which was characterized by XRD, FTIR, UV vis, TGA, and zeta potential, and the results revealed that ZIF-8@RAPA with a dodecahedral morphology, a particle size of 82 nm ± 4.7 nm, and a drug-loading rate of up to 11.53 % was successfully synthesized and that the loaded RAPA could achieve long-lasting slow release. Furthermore, we monitored the structural evolution of ZIF-8@RAPA in PBS. We found that the structural stability of ZIF-8@RAPA could be maintained for up to 6 weeks, followed by the gradual cleavage and disintegration of the crystal structure, and the reformation of micro-crystals (dia(Zn)) at 8 weeks, which is presumed to be affected by the [HPO 4 ] 2- in the PBS solution. In addition, the biocompatibility of the ZIF-8@RAPA delivery system was comprehensively evaluated using macrophage RAW 264.7 and the zebrafish embryo model. The results revealed that the biotoxicity of ZIF-8@RAPA was concentration dependent and that it had good biocompatibility when it was applied at concentrations lower than 100 μg/mL. In summary, our study preliminarily elucidated the in vitro disintegration and reconstruction mechanisms of nano-ZIF-8@RAPA crystals and demonstrated their feasibility for application in biomedical fields.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
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IF 5.4
Yaning Li,Yue Wang,Hongchao Ma
The tumor microenvironment (TME), characterized by hypoxia, limited H 2 O 2 availability, and elevated glutathione (GSH) concentrations, challenges reactive oxygen species (ROS)-based therapies. To address these, we developed a GOx@Cu-ZIF-8/DOX (GCZD) nanoplatform combining chemotherapy (CT), chemodynamic therapy (CDT), and starvation therapy (ST). This system utilizes Cu-incorporated ZIF-8 (Cu-ZIF-8) as a versatile carrier to load glucose oxidase (GOx) and doxorubicin (DOX). Under acidic TME conditions, GCZD disintegrates, releasing GOx, Cu 2+ , and DOX. GOx catalyzes intratumoral glucose oxidation, producing gluconic acid and H 2 O 2 to achieve a triple-therapeutic effect. Gluconic acid maintains a weakly acidic environment for continuous GCZD degradation. Glucose depletion induces metabolic starvation. Generated H₂O₂ serves as substrate for Cu 2+ -mediated Fenton-like reactions, boosting ROS production. Cu 2+ exhibits catalytic activity, efficiently converting TME and GOx-generated H 2 O 2 into cytotoxic ·OH. Increased ROS concentration enhances biological macromolecule oxidation damage, intensifying CDT. Additionally, Cu 2+ oxidizes GSH to form GSSH and Cu + . This inhibits GSH-mediated ROS degradation and leverages excellent Fenton-like activity of Cu + to further enhance CDT. Simultaneously, DOX exerts chemotherapeutic effects by intercalating into DNA and inhibiting topoisomerase II, blocking tumor cell proliferation. This integrated approach, combining enhanced ROS generation, tumor cell metabolic intervention, and DNA damage, demonstrates enhanced antitumor efficacy by simultaneously targeting multiple cancer cell vulnerabilities.
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WATER AIR AND SOIL POLLUTION
·
2025
·Vol. 236
·期 15
·1-24
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IF 3
Zang Shuyan,Wang Shuai,Li Xue,Chen Xinru,Wang Qian,Wang Juan
The removal of both organic and inorganic arsenic is crucial for safeguarding the environment and human health, which constitutes a key aspect of sustainable development. In this study, a novel method integrating Fenton oxidation with ZIF-8 adsorption was developed for the simultaneous treatment of roxarsone (ROX) and arsenite (As(III)) from wastewater. ZIF-8 was hydrothermally synthesized and characterized using X-ray Photoelectron Spectroscopy (XPS), Fourier Transform Infrared Spectroscopy (FT-IR), X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Elemental Mapping (EM), Brunauer–Emmett–Teller (BET) surface area analysis, and zeta potential analysis. Comprehensive characterization demonstrated that the synthesized ZIF-8 exhibited a well-defined rhombic dodecahedral morphology with smooth crystal surfaces and an exceptionally high specific surface area of 1836.23 m 2 /g. Under the optimized conditions for Fenton oxidation (4.90 mmol/L H 2 O 2 , 0.1380 g/L FeSO 4 ·7H 2 O, pH 3, 30 min) and ZIF-8 adsorption (0.1 g/L ZIF-8, pH 6, 180 min, 25℃), the integrated system exhibited remarkable removal efficiencies of 92.32% for ROX (20 mg/L) and 95.16% for As(III) (1 mg/L). Specifically, compared to the individual processes, the removal efficiency of ROX was increased by 20.59% (versus Fenton-only) and 52.63% (versus ZIF-8-only), while that of As(III) was enhanced by 29.17% and 35.51%, respectively. Additionally, the integrated system exhibited maximum adsorption capacities of 107.76 mg/g for ROX and 17.70 mg/g for As(III), further confirming the presence of synergistic effects between Fenton oxidation and ZIF-8 adsorption. The adsorption processes for ROX and As(III) followed pseudo-second-order kinetics and were best described by the Langmuir adsorption model, suggesting chemisorption and monolayer adsorption on a homogeneous surface. The removal mechanism in the synergistic method involved three primary pathways: oxidation reactions (•OH), electrostatic interactions (-OH/-NH 2 ), and precipitation (FeAsO 4 ). This study demonstrates that the proposed synergistic method (Fenton@ZIF-8) is a promising technology for the simultaneous removal of both organic and inorganic arsenic species from contaminated water, with strong potential for practical application in wastewater remediation.
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RUSSIAN JOURNAL OF GENERAL CHEMISTRY
·
2025
·Vol. 95
·期 9
·2457-2467
·
IF 0.8
Sun Yanhua,Kong Xiangyang,Xi Shuoyan,Xu Zhuoyue,Zhang Yuhan
Salvianolic acid (SAB) is a natural flavonoid compound possessing significant pharmaceutical value. However, the extraction and purification of SAB from natural products are hindered by the complexity and low concentration of matrix components. In this research, a new surface imprinted polymer with core-shell structure, denoted as ZIF-8@MIPs, was successfully developed using porous metal-organic frameworks (MOF) ZIF-8 as the scaffold. ZIF-8@MIPs exhibited remarkable selective extraction and enrichment of SAB from Salviorrhiza . Series of characterizations and adsorption experiments demonstrated that ZIF-8@MIPs possessed a typical core-shell octahedral structure with a high specific surface area. The resultant high-density imprinted sites allowed the ZIF-8@MIPs to exhibit a high adsorption capacity (46.7 mg/g) and exceptional selectivity (IF = 3.11) for SAB, while achieving adsorption equilibrium within 90 min. Notably, the ZIF-8@MIPs maintained an adsorption capacity of 89.2% for SAB after 7 cycles of adsorption-desorption experiments, indicating good reusability. Furthermore, a solid-phase extraction column was established utilizing the ZIF-8@MIPs as the adsorbent, and the content of SAB in the Salviorrhiza extract was determined by combining this with HPLC. The spiked recovery rate ranged from 87.70 to 92.90%, with RSD of 2.87–3.43%, demonstrating the reliability and reproducibility of this method. In conclusion, the ZIF-8@MIPs developed in this study offer a promising approach for the selective extraction of active flavonoids from natural matrices, with potential application in application prospects.
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HYDROMETALLURGY
·
2025
·
IF 5.3
Jun Li,Ruihui Wu,Shengjun Tian,Ronghao Liu,Huiying Wei,Yanzhao Yang
The NdFeB magnets are the most widely used permanent magnetic materials in the international arena, and the recovery of Nd(III) from the growing number of waste-NdFeB magnets is becoming increasingly crucial. In this study, a novel synergistic extractant consisting of bis(2,4,4-trimethylpentyl) phosphonic acid (Cyanex 272) and 8-hydroxyquinoline (8-HQ) is proposed for the recovery of Nd(III) from waste-NdFeB magnets. First, the influence of the ratio of the two extractants on the synergistic extraction coefficient was investigated. The coextraction coefficient ratio of the two extractants Cyanex 272 and 8-HQ was 1:1. The extraction behaviors under different conditions, such as the extractant concentration, aqueous phase pH (pH = 5), and oscillation time (1 min), were investigated. Under optimal conditions, the extraction efficiency reached 99.6 %. A chelating extraction mechanism was proposed on the basis of UV–vis spectroscopy, FT-IR spectroscopy, and NMR spectroscopy methods. The excellent extraction efficiency was maintained after five cycles of extraction and stripping, indicating the potential for application in light and heavy rare earth separation processes. Overall, this study aims to provide a new economically viable method for the recovery of Nd(III) from waste-NdFeB magnets.
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ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Yunfei Tang,Mengmeng Xiao,Tongtong Duo,Xiaowan Zhang,Ziyue Chen,Wei Wei
The abnormal expression of monoamine oxidase B (MAO-B) and the soluble oligomer (Aβo) formed by β-amyloid deposition play key roles in the pathogenesis of Alzheimer’s disease. However, the simultaneous detection of MAO-B and Aβo remains a huge challenge. Herein, a bimetallic core–shell probe ZIF-8 embedding rhodamine 6G (Au/Rh6G/Pd@ZIF-8) with peroxidase-like activity is designed to detect MAO-B and Aβo simultaneously. MAO-B catalyzes the substrate phenethylamine (PEA) to produce H2O2, which oxidizes thiamine with the catalysis of Au/Rh6G/Pd@ZIF-8 to produce a fluorescent product that emits a strong fluorescence at 440 nm. When Aβo is present in the system, due to the specific coordination between Aβo and Zn2+, the intact ZIF-8 structure collapses, leading to Rh6G release and fluorescence recovery. The simultaneous determination of MAO-B and Aβo by Au/Rh6G/Pd@ZIF-8 is realized. The results showed that the designed biosensor had high specificity and sensitivity, a wide detection range, and a low detection limit for MAO-B and Aβo simultaneous detection. Fluorescence signals for MAO-B and Aβo detection did not interfere with each other because they are excited separately, which provides more valuable data for the diagnosis of Alzheimer’s disease.
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JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Ning Liu,Jie Wang,Huiyu Yang,Fan Cheng,Shuguang Bi,Guoliang Liu,Ying Ou,Hai Liu,Chunli Gong
In order to improve the proton conductivity, CH 3 OH barrier performance and long-term durability of proton exchange membranes in direct methanol fuel cells (DMFCs), herein, a novel functional nanofiber substrate (IL-ZIF-8@PVDF) was prepared by in situ growing metal-organic framework (ZIF-8) on poly(vinylidene fluoride) (PVDF) nanofibers, followed by modification with ionic liquid (IL) containing sulfonic acid groups. PVDF nanofibers can provide flexible mechanical support for ZIF-8, thereby effectively solving the processing difficulties of ZIF-8 caused by its brittleness. Further IL modification of ZIF-8 can not only increase the compatibility between ZIF-8@PVDF and the filling polymer, but also utilize the continuous PVDF nanofiber network to establish long-distance continuous H + transport pathways within the membrane. The as-prepared sulfonated poly (ether ether ketone) impregnated IL-ZIF-8@PVDF composite membrane showed a very high proton conductivity of 161.92 mS cm −1 (80 °C). Meanwhile, the presence of nanofiber backbone and ZIF-8 inside the membrane effectively limited the swelling and methanol permeation. The peak power density (PPD) of the DMFC output equipped with the membrane is up to 114.86 mW cm −2 (2 M methanol, 80 °C), 1.28 times that of the commercial Nafion 211. The durability test suggested that the composite membrane assembled DMFC possessed excellent open circuit voltage stability (only 6.3 % attenuation after 320 h of continuous testing). This work provides a new design idea for PEMs for DMFCs.
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Inorganics
·
2026
·Vol. 14
·期 2
·43
·
IF 3
Huili Ren,Chenxia Gao,Siqi Huang,Libo Du,Shuang Liu,Xi Cao,Yuguang Lv
The proliferation of antibiotic resistance urgently demands the development of novel non-antibiotic-dependent antimicrobial strategies. Metal–organic framework material ZIF-8, with its tunable structure and excellent biocompatibility, shows great promise in the field of photocatalytic antibacterial applications. However, pure ZIF-8 suffers from limitations such as a narrow light absorption range and high carrier recombination rates. Doping ZIF-8 with transition metals such as cobalt or copper, herein denoted as M-ZIF-8 (M=Co, Cu), can significantly broaden its photoresponsive spectrum, promote reactive oxygen species (ROS) generation, and enable controlled metal ion release, thereby enhancing antimicrobial performance. Nevertheless, the release of metal ions also introduces potential biotoxicity concerns, limiting practical applications. This paper systematically reviews the trade-off between the photocatalytic antibacterial mechanism and biotoxicity of metal-doped M-ZIF-8 (M=Co, Cu), focusing on material design principles, antibacterial pathways, toxicity manifestations and mechanisms, as well as optimization strategies for “enhancing efficacy while reducing toxicity.” It further proposes future research challenges and directions in mechanism elucidation, smart material development, standardization, and industrialization to advance the safe and efficient application of these materials in medical and environmental fields.
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JOURNAL OF MEMBRANE SCIENCE
·
2026
·
IF 8.8
Hui You,Xiang Xu,Wencan Luo,Lancai Long,Jun Du,Shunmin Yi,Wanyu Liu
The development of reverse osmosis membranes that simultaneously achieve high water permeability and excellent salt rejection is an urgent yet challenging goal for sustainable desalination. Two-dimensional (2D) nanofillers offer a promising pathway to break the inherent trade-off by creating fast water-transport channels. Herein, we engineered a high-performance thin-film nanocomposite (TFN) membrane by incorporating lamellar zeolitic imidazolate framework-8 nanosheets (ZIF-8 NSs) into the polyamide selective layer. The ZIF-8 NSs, synthesized via a facile surfactant-directed approach, possess an ultrathin thickness of ∼5.5 nm and a large lateral size of ∼0.75 μm. When embedded at an optimal loading, the TFN membrane demonstrates a remarkable water permeability of 9.83 L m −2 h −1 MPa −1 , which is ∼37% higher than the pristine thin-film composite (TFC) membrane, while maintaining a high Na 2 SO 4 rejection of 97.9%. This superior performance, significantly surpassing that of membranes filled with conventional ZIF-8 nanoparticles, is attributed to the synergistic effect of the molecular-sieving function of intrinsic ZIF-8 pores and the low-resistance nanochannels formed by the interlayer galleries between the well-dispersed nanosheets, which concurrently facilitate a more cross-linked polyamide network. This work provides a viable and scalable strategy for using 2D MOF nanosheets to design advanced separation membranes.
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FOOD CHEMISTRY
·
2026
·
IF 10.4
Rui Sun,Pei Lv,Bingqing Shen,Qian Wu,Yuan Xue,Lin Chen,Weibin Li,Zhenjiang Liu
Imidacloprid (IMI) has potential hazards to human health and honeybees. Herein, we developed a highly sensitive fluorescence polarization immunoassay (FPIA) based on ZIF-8-derived carbon particles (ZIF-8-C) for the detection of IMI in agricultural samples, and studied the effect of different sizes of ZIF-8-derived carbon-antibody conjugates (ZIF-8-C-PDA-mAb) and fluorescence lifetime on the detection sensitivity. The results found that the detection sensitivity of FPIA was related to the particle sizes of ZIF-8-C-PDA-mAb. Under optimized conditions, 220 nm ZIF-8-C-PDA-mAb-based FPIA showed the best limit of detection of 0.46 μg/L, which was 47-fold lower than that of the traditional mAb-based FPIA. The recoveries ranged from 86.75 to 111.75%, with a relative standard deviation below 8.44%. Additionally, FPIA results correlated well with HPLC, with a correlation coefficient of 0.998. This strategy provides a great potential FPIA method for rapid and high-sensitivity detection of pesticides and other small molecule pollutants in environmental and agricultural samples.
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