COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2023
·
IF 5.2
Chao Su,Bin Pei,Peilun Shen,Qifang Zheng,Jinpeng Cai,Dianwen Liu
To solve the problem of depression failure caused by xanthate pre-adsorption, this paper comprehensively studies the mechanism and characteristics of L -cysteine (L-C) adsorption on the surface of galena with or without xanthate through micro-flotation, X-ray photoelectron spectroscopy (XPS), inductively coupled plasma-optical emission spectrometry (ICP-OES), field emission scanning electron microscope-energy dispersive spectroscopy (FESEM-EDS), time of flight secondary ion mass spectrometry (ToF-SIMS), zeta potential , UV–visible spectrum, and contact angle experiments. SBX has a significant effect on the adsorption behavior of L-C on the surface of galena. The micro-flotation results showed that the L-C has very good depression effect on galena. However, this is invalid when sodium butyl xanthate (SBX) is preferentially introduced. L-C can be adsorbed on galena through the reaction of -SH and -NH 2 with exposed lead sites. In addition, the lead species dissolved from the surface of galena can be re-adsorbed after complexing with L-C in solution. However, L-C can hardly interact with the surface of galena pre-treated by SBX, and it is only adsorbed by electrostatic force in the form of [Pb(C 3 H 7 NO 2 S)] 2+ and [PbOH(C 3 H 7 NO 2 S)] + complexes. This study is expected to achieve cyanide free separation of Cu-Pb bulk concentrate.
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APPLIED CATALYSIS A-GENERAL
·
2017
·
IF 4.339
Zhixiong Luo,Somboon Chaemchuen,Kui Zhou,Andres Alvarado Gonzalez,Francis Verpoort
A series of metal organic frameworks (MOFs) MDABCO (M = Co, Ni, Cu, Zn; DABCO = 1,4-diazabicyclo[2.2.2]octane) are utilized as catalysts for the bulk ring-opening polymerization of l -lactide. The catalytic activity varies in the order CuDABCO, NiDABCO < ZnDABCO, CoDABCO. By adding lactic acid, we unexpectedly observed enhanced catalytic activity. The combined use of lactic acid and ZnDABCO during polymerization results in a highly active polymerization system, along with the gradual change of MOFs structure caused by an increased acid concentration. Compared to related homogeneous fragments, such as zinc nitrate and 1,4-diazabicyclo[2.2.2]octane, ZnDABCO is found to afford highly isotactic polylactide, which would be ascribed to the unique structural properties of MOFs.
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Journal of Chromatography Open
·
2025
·
IF 3.2
Zhixu Chen,Rongkai Gu,Mingming Zhao,Kefeng Linghu,Huanwei Fan,Tingting Zhang,Jincai Wang,Zhengjin Jiang
The N-terminal region of the polymerase subunit (PAN) is considered as the most promising target for the development of broad-spectrum antivirals, since it is highly conserved in structure and sequences among different influenza strains. In this study, a PAN based at-line nanofractionation (ANF) platform was applied to rapidly screen for PAN inhibitors from Rubus idaeus L. extract which presented good inhibitory effect on PAN with a half maximal inhibitory concentration (IC 50 ) value of 11 μg/mL. Eight PAN inhibitors were successfully screened out, comprising four organic acids and four flavones. In parallel, magnetic ligand fishing was used to isolate the PAN ligands from the extract, and finally four compounds were fished out and considered as PAN ligands (including avicularin, quercetin-3-O-rutinoside, ellagic acid and luteoloside) which were also identified by the ANF platform. Among them, ellagic acid and luteoloside displayed satisfactory in vitro inhibitory activity against PAN, with IC 50 values of 1.31 ± 0.33 and 6.23 ± 0.97 μM, respectively. The molecular docking and dynamic simulations revealed that ellagic acid and luteoloside bind to PAN in a distinctly different mode compared to baloxavir. These compounds formed direct interactions with catalytic pocket residues and adjacent amino acids in PAN, establishing hydrogen bonds and water-mediated bridges that modulated the protein's secondary structure and stability. The result from the study suggests that ellagic acid and luteoloside could serve as promising anti-influenza molecules. Furthermore, the ANF platform was proved effective for high-throughput screening of PAN inhibitors from complex herbal extracts, highlighting its significant potential for future anti-influenza drug development.
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ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Hang Su,Shuo Huang,Jingming Lan,Xin Gao,Hongyan Yue
Chiral recognition and detection of enantiomer molecules are crucial for biochemical sensing and pharmaceutical applications. In this study, a rod-shaped left-handed cellulose nanocrystal (CNC, length of ∼75 nm and diameter of ∼10 nm) is extracted from strobili fibers of plane trees through acid hydrolysis. Then, octahedral CuO/C nanoparticles (∼450 nm) are synthesized via thermal decomposition of the Cu-MOF precursor. Finally, CNC@CuO/C is prepared by the self-assembly of CNC and CuO/C driven by solvent evaporation. The CNC@CuO/C electrode demonstrates a remarkable enantioselectivity to l-cysteine (l-Cys) and achieves a high sensitivity of 3.14 μA·mM–1 and a low detection limit (LOD) of 4.62 μM. The electrode exhibits an excellent anti-interference capability, reproducibility, repeatability (RSD < 5%), and stability (>90% after 15 days). This presents a sustainable approach to use renewable nanomaterials, and it also shows a promising potential for clinical diagnostics.
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PubMed
高影响因子
ACTA PHYSIOLOGIAE PLANTARUM
·
2021
·Vol. 43
·期 12
·1-11
·
IF 2.354
Shu Xiao,Zhang KeRong,Zhang QuanFa,Wang WeiBo
Acid rain remains a global environmental issue that can indirectly impact plant root growth and health by mediating soil acidification. The impact of acid rain on the roots of Jatropha curcas L., however, has not been thoroughly evaluated to date in soils with a range of buffering capacities. We, therefore, explored the ability of J. curcas roots to tolerate acid rain in a range of soil types by exposing samples to simulated acid rain (SAR) (pH2.5, pH3.5, pH4.5, pH5.6) and then examining the impact of such exposure on root morphology, relative growth rate (RGR root ), nutrient absorption, enzymatic activity, and microbial biomass. Yellow–brown soil (YBS) and purple soil (PS) were found to be better able to buffer SAR-mediated acidification, thereby providing superior benefits to J. curcas root growth as compared to red soil (RS) and yellow soil (YS) under these experimental conditions. SAR (pH 4.5) significantly enhanced Ca, K, and Mg absorption by J. curcas roots, thereby improving their growth characteristics, whereas SAR (pH 2.5) impaired K and Mg absorption and thus suppressed root growth. K and Mg absorption characteristics were regulated by changes in plasma membrane H + -ATPase activity under these different SAR treatment conditions. Morphological and growth (RGR root ) adaptations of J. curcas roots to SAR treatment were associated with superoxide dismutase activity levels therein. SAR (pH 4.5) was sufficient to bolster the rhizosphere microbial activity of J. curcas seedlings, and correlation analyses revealed that root growth was regulated by rhizosphere microbial biomass P content under SAR treatment conditions.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2015
·
IF 4.097
Guoxin Song,Chunli Xu,Baoxin Li
We report a method for visual differentiation between the l - and d -forms of mandelic acid (MA). It is based on the chirality of l -tartaric acid-capped gold nanoparticles ( l -TA-capped AuNPs, ca. 13 nm in diameter) that can be used as chiral selector for l - and d -forms of MA. On addition of l -MA to a solution of the l -TA-capped AuNPs, a color change from red to blue can be seen, while no color change is found on addition of d -MA. The chiral assay can be used to determine the enantiomeric excess of l -MA in the range from −100% to 100%. The effect can be detected with bare eyes and quantified by spectrophotometry. Notably, this method does not require the complicated chiral modification. The method excels by its sensitivity, low cost, good availability of materials, and its simplicity.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2015
·Vol. 31
·期 5
·890-894
·
IF 0.875
Wu Huiyong,Li Jianhui,Wei Junchao,Dai Yanfeng,Peng Zhiping,Chen Yiwang,Liu Tianxi
Poly( L -glutamic acid)(PLGA) was grafted onto the surface of mesoporous silica nanoparticles(MSN) via the ring opening polymerization of γ -benzyl- L -glutamate N -carboxyanhydride(BLG-NCA) and its subsequent deprotection of benzyl groups. The PLGA chains were cross-linked with cystamine, and thus forming a type of redox responsive drug delivery system(MSN- c PLGA). The structures were characterized by Fourier transform infrared spectrometry(FTIR), transmission electron microscopy(TEM) and energy disperse spectrometry(EDS), demonstrating that disulfide groups existed on the surfaces of MSN- c PLGA particles. The thermal gravimetric analysis(TGA) results show that the PLGA mass fraction is about 33.4% in the MSN-cPLGA hybrid. The in vitro drug release experiments showed that the MSN- c PLGA hybrid can realize the controlled release of model drugs(5-fluorouracil) in response to redox environment. Even 0.1 mmol/L dithiothreitol(DTT) can accelerate the drug release speed, and a concentration of 10.0 mmol/L DTT is higher enough to trigger the open of cross-linked PLGA network so as to realize rapid release of drugs. All the results demonstrate that the cross-linked PLGA chains on the surface of MSN could act as efficient gatekeepers to control the on-off of the pores, showing potential application in drug delivery system.
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MONATSHEFTE FUR CHEMIE
·
2019
·Vol. 150
·期 7
·1349-1354
·
IF 1.501
Li Yunhao,Liu Shiquan
Abstract A porous silica gel with both COOH and NH 2 groups was synthesized in one pot by the addition of l -glutamic acid ( l -GA) into a synthesis medium consisting of tetraethyl orthosilicate, water, ethanol, and 1-butylamine. The inclusion of l -GA in the as-synthesized product ( l -GA-SiO 2 ) was evidenced by FT-IR and TG measurements. The l -GA was chemically bonded with silica as indicated by the shift of FT-IR bands at 1510 and 1400 cm −1 in the spectrum of l -GA to higher wavenumbers of 1540 and 1460 cm −1 in the one of l -GA-SiO 2 . The TG analysis showed that the l -GA-SiO 2 had an increase of weight loss by 5.6% due to the decomposition of the included l -GA which was centered at around 313 °C, suggested by a new peak in the DTG curve. Compared with the one synthesized without l -GA, the l -GA-SiO 2 was more aggregated with smaller surface area. However, the latter showed a higher removal efficiency by 17.1% toward zinc ions in water than the former and the adsorbed ions were hardly released again into water from the used adsorbent. Graphical abstract
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2012
·Vol. 125
·期 4
·3092-3099
·
IF 1.289
Suwen Ye,Licheng Tan,Yiwang Chen,Junchao Wei,Weihua Zhou
A series of aliphatic biodegradable poly(butylene succinate)- co -oligo( L -valine) (PBSVAL) copolyesters were synthesized with dimethyl succinate, 1,4-butanediol (BDO), and oligo( L -valine) (OVL) as reagents. The GPC results show that the weight average molecular weight ( M w ) of the copolyester with a feed ratio (PBS/OVL) of 0.9/0.1 (PBSVAL 10 ) is 4.9 × 10 4 g/mol, and its polydispersity index is 1.68. All the copolyesters were more thermally stable than the pristine poly(butylene succinate) (PBS). The incorporation of valine units into the copolyesters eventually led to the decrease of the crystallization temperature, melting temperature, while increase of crystallization enthalpy and melting enthalpy. The crystal structure of the copolyesters is similar to pure PBS except for higher degrees of crystallinity; also there was a trend to higher degrees of crystallinity with increasing content of valine. From the enzymatic degradation experiment, it is clear that the PBSVAL 10 copolyester shows less weight loss as compared to pure PBS which is due to PBSVAL 10 with higher degree of crystallinity. The morphology of the copolyester films after degradation was also studied by the scanning electron microscopy. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Jingrong Ma,Rongrong He,Yuan Chai,Xiaoshan Long,WenZheng Shi,Haiming Chen,Chuang Pan,Yongqiang Zhao
In order to explore the potential applications of thermal modified (90 and 120 °C, 20 min) coconut globulins (CG) in encapsulation systems, the long-term emulsion stability was improved by adding xanthan gum (XG). Subsequently, the protection effect of thermal modified CG-XG emulsion on curcumin (Cur) was demonstrated. The results showed that the XG decreased the interfacial adsorption of heated-CG. When 0.1 % XG was added, the K r value and interfacial viscoelasticity of 90 °C-CG were significantly increased. However, when the concentration of XG increased to 0.2 %, the K r value and interfacial viscoelasticity showed significant decrease. The interfacial viscoelasticity of 120 °C-CG decreased with the increase of XG. However, the emulsion prepared by 120 °C-CG-XG had a higher viscosity and a more compacted three-dimensional gel network structure, which led to the higher long-term stability. The heated-CG-XG emulsion system showed an excellent encapsulation effect on Cur, especially for the 120 °C-CG-0.2XG encapsulation system, which could improve the bioaccessibility of Cur from 18.21 % to 36.23 % ( p < 0.05). Our work indicated that the 120 °C-CG emulsion system have the potential use in Cur encapsulation delivery, which is of great significance for the commercial application of thermal modified CG.
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PubMed
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Yue Han,Xuehui Tang,Xiangyu Wu,Hongyi Shi,Lei Huang,Lei Wei,Mingmin Li,Yue Zhang
l -Cysteine ( l -Cys) is a significant biomarker for various diseases, including liver disease, skin disorders, and Parkinson’s disease, making its detection crucial for diagnostic purposes. In this study, we present a novel colorimetric sensing platform for l -Cys detection. Using ZIF-8 as a precursor, a cobalt-based single-atom catalyst (Co-N-C) was synthesized through pyrolysis, adsorption, and activation processes. The resulting Co-N-C catalyst exhibited remarkable oxidase-like (OXD-like) activity, effectively facilitating the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) to form oxTMB, which resulted in a distinct blue color. However, due to its strong reducibility, l -Cys can scavenge reactive oxygen species (ROS) generated by the Co-N-C catalyst, thus inhibiting the oxidation of TMB. By monitoring the color change in the solution, we developed a highly sensitive colorimetric assay for l -Cys detection. The assay demonstrates excellent selectivity and has a detection limit of 0.1 µM, with a linear detection range from 0.1 to 10 µM. This work offers an efficient approach for detecting l -Cys and establishes a new framework for designing high-performance nanozymes.
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PubMed
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INDUSTRIAL CROPS AND PRODUCTS
·
2025
·
IF 6.2
Tao Sun,Siying Ren,Jian Hu,Jiatao Zhang,Linze Liu,Jiahui Du,Xing Wang,Yuming Deng,Xueyan Yun,Tungalag Dong
Biodegradable PLLA-based cast films were prepared via melt blending poly(L-lactic acid) (PLLA) with poly(L-lactic acid-co-butylene itaconate) (PLBI), poly(L-lactic acid-co-glycolic acid) (PLGA), and poly(L-lactic acid-co-butylene itaconate-co-glycolic acid) (PLBIGA) copolymers to enhance mechanical, barrier, and degradation properties for dairy packaging applications. Copolymers were synthesized using a one-step melt polycondensation method, and the film properties were effectively controlled by adjusting the blending ratios. All blended films exhibited significantly improved toughness while maintaining high transparency. Specifically, PLLA/PLBIGA20 % film demonstrated a 90.1 % reduction in oxygen transmission rate (OTR) and a 54.3 % reduction in water vapor transmission rate (WVTR) compared to pure PLLA, and PLLA/PLBI20 % film reduced ultraviolet (UV) transmittance to 53 % in the 280–320 nm range. The soil degradation rates of blended films were notably higher than pure PLLA, with distinct degradation mechanisms observed for each copolymer; notably, PLLA/PLBIGA20 % film degraded simultaneously in both amorphous and crystalline regions. Blended films met food-contact safety standards and, when applied to commercial yogurt packaging, effectively preserved lactic acid bacteria viability, outperforming pure PLLA film. These findings demonstrate the strong potential of PLLA-based blended films as sustainable packaging solutions for dairy products.
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