JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2023
·
IF 5
Safdar Ali Amur,Najaf Ali Soomro,Quratulain Khuhro,Yun Wei,Hao Liang,Qeping Yuan
In the present study, multifunctional natural drug gentiopicroside (GPS) has been encapsulated into zeolitic imidazolate frameworks (ZIF-8) in aqueous solution at room temperature. ZIF-8 MOFs were observed to be suitable and favorable carrier for delivery of GPS. The single step synthesis of GPS@ZIF-8 reflected high loading efficacy of GPS into ZIF-8 of about 84%, while, its loading capacity was revealed to be 10.77%. GPS@ZIF-8 and ZIF-8 were characterized through different techniques. Morphology of GPS@ZIF-8, assessed through SEM and TEM , revealed to be uniform and hexagonal shape which is much alike to pure ZIF-8. Moreover, average particle size of ZIF-8 and GPS loaded into ZIF-8, as observed through DLS, was 125 nm and 149 nm, respectively; increased size of GPS@ZIF-8 depicted a well efficient encapsulation of GPS. The thermal stability showed that the GPS when loaded into ZIF-8 remained thermally constant up to 298 °C. The free drug GPS release profile from GPS@ZIF-8 was studied at 37 °C in PBS solution with two pH i.e. 5.0 and 7.4. The GPS@ZIF-8 reflected significant faster release of GPS in acidic medium i.e. 81.31% which was higher than the release of GPS in physiological medium i.e. 20.03%. Thus, results of the present study revealed that the ZIF-8 can be used as a potential carrier for controlled delivery of GPS against diseased cells in future. GPS@ZIF-8 in contrast to free GPS showed highest inhibition zone against gram-negative and gram-positive bacteria. Therefore, the composite material can be potentially considered for the therapeutic applications.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED CLAY SCIENCE
·
2021
·
IF 5.467
Hefu Li,Dan Meng,Peng Qi,Jun Sun,Hongfei Li,Xiaoyu Gu,Sheng Zhang
Aluminum hypophosphite (AHP) is an effective flame retardant to thermoplastic polyurethane (TPU), but it also results in increase on smoke release caused by the presence of phosphorus groups. In this work, a novel synergistic flame retardant was fabricated from metal organic framework (ZIF-8) and sepiolite (SEP). For the compsosite of TPU/8.0AHP/1.0ZIF-8@SEP, limiting oxygen index (LOI) reached 27.5% and it satisfied the UL-94 V-0 grade. The heat release rate and the total heat release decreased by 78.9% and 39.1% compared with the control TPU respectively. The increased smoke production caused by AHP was partly adsorbed by ZIF-8@SEP, therefore, the sample of TPU/8.0AHP/1.0ZIF-8@SEP showed the lowest smoke release in cone calorimeter test. Unsimilar as other flame retardant, the using of 8.0AHP/1.0 ZIF-8@SEP just brought less than 2.0% loss on tensile strength and 7.8% drop on the elongation at break of TPU. Consequently, the ZIF-8@SEP was documented as excellent synergistic flame retardant for TPU and it brought limited damage on mechanical performance.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Yihan Wu,Biyun Li,Xiangxue Wang,Shujun Yu,Hongwei Pang,Yue Liu,Xiaoyan Liu,Xiangke Wang
The water stable core-shell microspheres (Fe 3 O 4 @ZIF-8) with strong magnetism were successfully fabricated through a facile modification strategy. Concrete procedures included firstly pretreatment of Fe 3 O 4 core with anionic polyelectrolyte to acquire negatively charged Fe 3 O 4 particle surface, followed by nucleation through attracting Zn 2+ cation, and then growth of a thin layer of ZIF-8 (~25 nm). Various characterization techniques (SEM, TEM, FT-IR, XRD, VSM, BET and XPS) indicated that the Fe 3 O 4 @ZIF-8 microspheres were highly stable and magnetic with a large specific surface area (606.91 m 2 /g) and fairly sufficient functional groups ( NH , OH, COOH, Zn O, N O and C N ). Multi-factors affecting the radionuclides removal performance on Fe 3 O 4 @ZIF-8 was adequately explored, comprising contact time, temperature, pH, ionic strength, co-existing ions and extreme conditions. And the results showed that Fe 3 O 4 @ZIF-8 exhibited fast reaction kinetics (~30 min to achieve equilibrium), excellent uptake capabilities (539.7 mg U/g and 255.6 mg Eu/g), remarkable selectivity and favorable physicochemical stability. These researches suggested that Fe 3 O 4 @ZIF-8 could not only simultaneously achieve favorable stability and functionality, but also easily to be separated by external magnetic field after used in radioactive sewage treatment, which was of considerable practical utility in extracting radioactive wastes though in harsh circumstance.
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Nuan Xu,Zhenhua Tang,Yan-Ping Jiang,Junlin Fang,Li Zhang,Xiaofang Lai,Qi-Jun Sun,Jing-Min Fan,Xin-Gui Tang,Qiu-Xiang Liu,Ji-Kang Jian
Antibiotics play an essential role in the treatment of various diseases. However, the overuse of antibiotics has led to the pollution of water bodies and food safety, affecting human health. Herein, we report a dual-emission MOF-based flexible sensor for the detection of antibiotics in water, which was prepared by first encapsulating rhodamine B (RhB) by a zeolite imidazolium ester skeleton (ZIF-8) and then blending it with polyvinylidene difluoride (PVDF). The luminescent properties, structural tunability, and flexible porosity of the MOF-based composites were combined with the processability and flexibility of polymers to prepare luminescent membranes. The sensor is capable of dual-emission ratiometric fluorescence sensing of nitrofurantoin (NFT) and oxytetracycline (OTC), exhibiting sensitive detection of fluorescence burst and fluorescence enhancement, respectively, with detection limits of 0.012 μM and 8.9 nM. With the advantages of visual detection, high sensitivity, short detection time, and simplicity, the highly sensitive ratiometric fluorescent flexible sensor has great potential for detecting antibiotics in an aqueous environment. It will further stimulate interest in luminescent MOF-based mixed matrix membranes and their sensing applications.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Hua-Bin Yuan,Jin Cheng,Desheng Sha,ManMan Zhao,Tieling Xing,Guoqiang Chen
Multifunctional superhydrophobic materials demonstrate remarkable performance and promising application prospects in various fields. However, there is still considerable interest in developing milder superhydrophobic modification techniques for materials. In this study, we aimed to improve the surface roughness of cotton fabric by utilizing an in-situ growth method to incorporate zeolitic imidazolate framework-8 (ZIF-8). The fabric underwent a subsequent treatment with curcumin at room temperature, which served as a bridge for connection and provided multifunction to form a core–shell structure (curcumin/ZIF-8). Eventually, by implementing a mild thiol-ene click chemistry reaction, specifically by grafting octadecanethiol onto the C = C bond within the curcumin structure, we successfully prepared superhydrophobic modified cotton fabric known as SHCZC. The contact angle of the SHCZC material reached 168.7°, accompanied by a sliding angle of just 1°. Furthermore, SHCZC exhibited exceptional stability in harsh environments, enduring exposure to strong acids, alkalis, organic solvents, high and low temperatures, repeated washing, and abrasion. The material also demonstrated excellent thermal stability and remarkable breathability. Additionally, SHCZC possessed self-cleaning, UV-blocking, anti-fouling, antibacterial, anti-icing, and oil/water separation characteristics. The presence of these characteristics expands the potential of SHCZC beyond the field of superhydrophobic materials, positioning it as a highly advanced and versatile multifunctional material.
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
·
IF 4.4
Shiyu Li,Bo Fu,Huihui Li,Yatian Cao,Shengming Chen,Dong-Yu Guo,Le Li,Qinhe Pan
Bacillus anthracis spores can cause contagious anthrax, so it is significant for the public safety to detect its biomarker dipicolinic acid (DPA). Ratiometric fluorescent probes for DPA have attracted great interest because of the self-calibration effect, but they suffer from the complicated construction of dual-emitting materials. With combining fluorescence and second-order scattering (SOS), Eu-doped Zn-based metal–organic framework (ZIF-8) was here designed as a ratiometric probe for DPA, avoiding the completed construction of dual-emitting materials. Eu-doped ZIF-8 exhibited no fluorescence but possessed strong SOS ascribed to the nanostructure. However, the competitive coordination of DPA not only triggered the antenna effect of Eu 3+ but also caused the decomposition of Eu-doped ZIF-8. As a consequence, the fluorescence enhancement and the SOS weakness were observed upon the addition of DPA to Eu-doped ZIF-8. And thus, a ratiometric probe for DPA was constructed based on Eu-doped ZIF-8 by integrating fluorescence with SOS. The probe as-constructed could quantify DPA in a wide range of 0.1–150 μM with a rapid response (1 min) and a low detection limit (31 nM). It also displayed excellent manifestation for the analysis of food samples with reasonable accuracy (recoveries, 90.0%-101.5%) and satisfactory precision (RSDs, 0.6%-5.7%), offering a reliable tool for the supervision of the public safety.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Molecular Systems Design & Engineering
·
2023
·Vol. 9
·期 2
·205-213
·
IF 3.6
Chao Li,Fengchuan Guo,Zongxin Li,Naipu He,Wen Li,Xuerui Zhao
A chitosan/ZIF-8 hydrogel (CGsZx) was fabricated by in situ nucleation and growth of ZIF-8 crystals with a tunable morphology in chitosan hydrogel (CG) networks, and used as an ideal adsorbent for CO2. The CG has heterogeneous nucleation sites and was then soaked sequentially in a methanolic solution of Zn(NO3)2·6H2O and then a methanolic solution of 2-methylimidazole (2MeIM), and then combined with Zn2+ by forming a Zn–N coordination bond, and then the ZIF-8 crystals were formed on the CG. The growth and distribution of the ZIF-8 crystals in the CG network were achieved by regulating the molar ratio of Zn2+ to the glucosamine of the CS. In particular, the ZIF-8 crystals with spherical, cubic, tetrahedral, and cuboid shapes on the CGsZx were tuned by adjusting the molar ratio of Zn2+ to the glucosamine of CS. In addition, the ZIF-8 crystal with a petaloid morphology on the CG was obtained by using sodium tripolyphosphate (STPP) as a crosslinker. The synergistic effect of heterogeneous nucleation and coordination modulation were the main factors for the change of morphology and size of ZIF-8. The CGsZx exhibited a 441.7% adsorption capacity for CO2 which was higher than that of CG, and 65.3% higher than that of ZIF-8. After recycling five times, the adsorption capacity of the composite for C2 remained at 89.6%. The kinetics simulation indicates that the adsorption behaviour of CGsZx for CO2 was physical adsorption.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POROUS MATERIALS
·
2023
·
IF 2.6
Tang Yukuai,Chen Su,Liang Yusheng,Han Fengyan
We report a facile strategy to prepare the Pd nanoparticles loaded on porous N-doped carbon by direct carbonization of zeolitic imidazolate framework (ZIF-8) at 1000 o C. ZIF-8 not only serves as a precursor for N-doped carbon but also provides a framework to confine Pd nanoparticles with small size. The resulting Pd/ZIF-8(1000) has a regular morphology and excellent catalytic activity towards the reduction of nitrophenols (2-NP, 3-NP, and 4-NP) at room temperature with NaBH 4 as a reductant in aqueous solution. The enhanced performance is mainly due to N-doping, uniform dispersion and average size (2.3 nm) of Pd nanoparticles, large surface area, and synergistic effect between the metals (Pd NPs) and the support. Moreover, Pd/ZIF-8 (1000) remains the activity even after the 10th recycle experiment, indicating the catalyst has good stability. Importantly, ZIF-8(1000) can be applied as a framework to support highly uniform and stable noble metals with small size.
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2023
·Vol. 15
·期 36
·4736-4743
·
IF 3.1
Wanyu Pang,Yali Gao,Tuoping Hu,Xuemei Ma
Rapid and accurate determination of luteolin is of great significance for pharmaceutical quality control. Herein, a disposable and sensitive luteolin sensor was fabricated by a hydrothermal method with carbon paper as substrate where ZIF-8 grew on GR in situ. Notably, the large specific surface area of ZIF-8 provided active sites on the electrode surface and the ability of GR to promote electron transfer greatly improved the sensitivity towards the oxidation of luteolin. Under the optimum conditions, the ZIF-8@GR/CP showed excellent detection performance for luteolin with a linear detection range of 0.04–3.2 μM and 3.2–120 μM, with LOD of 12 nM (S/N = 3). Furthermore, this disposable and sensitive sensor was successfully applied for the quantitative detection of luteolin in a capsule of Lamiophlomis rotata.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Yingying Zhang,Xiaoci Cui,Xin Wang,Xiuyuan Feng,Yankang Deng,Weixia Cheng,Ranhua Xiong,Chaobo Huang
Currently, heavy metal such as Cu 2+ contaminants have posed a great threat for ecological security, and the discharge of sewage containing Cu 2+ into water and soil will cause damage to environment and even human health. At present, fluorescent solutions are generally used for Cu 2+ detection, but the they have defects such as easy leakage, difficult storage, poor photostability and inaccurate Cu 2+ detection. Herein, biomass solid-state fluorescence carbon fibers membrane detection platform ( NFE-CDs ) was firstly fabricated by encapsulating xylan carbon dots (CDs) into metal–organic framework ( MOF )( E-CDs @ZIF-8) using in situ growth methods and electrospinning technology. NFE-CDs was ued to improved response site of Cu 2+ by taking advantage of cooperative hybridization and electronic coupling effects. Owning its excellent fluorescence properties, NFE-CDs displayed excellent selectively for Cu 2+ based on ‘turn-on’ fluorescence response, ultra-short fluorescence response time (<1s) and detection limit (3.48 nM) that was well below U.S. EPA safety levels. The practical applications of NFE-CDs also exhibited high specificity for Cu 2+ detection in zebrafish and water samples (school lake, Xuanwu Lake and Yangtze River) with the recovery rates of 97%-112%. The developed fluorescence sensing platform was utilized to predict and detect water quality and safety by monitoring Cu 2+ change. This strategy demonstrates a promising biomass fluorescence platform for Cu 2+ detection for water treatment research and envrionment bioanalytical applications.
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2023
·Vol. 13
·期 39
·27203-27211
·
IF 3.9
Jiaxin Xiao,Shumin Zhu,Lingjun Bu,Yuan Chen,Ruoxi Wu,Shiqing Zhou
Halonitrophenols (HNPs) are an emerging type of aromatic disinfection byproduct, with detected concentrations of ∼nmol L−1 in source water and drinking water. Currently, there are no standard methods for identifying HNPs, and most of the reported methods are time-consuming and equipment-dependent. A core–shell metal–organic framework (MOF) based electrochemical sensor (Ag/ZIF-8@ZIF-67) capable of detecting 2,6-dichloro-4-nitrophenol (2,6-DCNP) is reported in this study. The electrochemical sensor obtains the concentration of 2,6-DCNP by detecting the peak current passing through the sensor. In this sensor, Ag nanoparticles (AgNPs) play a key role in electrochemical sensing by reducing nitro groups via electron transfer, and porous structure with a large surface area is offered by ZIF-8@ZIF-67. The cyclic voltammetry (CV) response of Ag/ZIF-8@ZIF-67 was found to be approximately 1.75 times and 2.23 times greater than that of Ag/ZIF-8 and Ag/ZIF-67, respectively, suggesting an ideal synergistic effect of the core–shell structures. The Ag/ZIF-8@ZIF-67 sensor exhibited exceptional sensitivity to 2,6-DCNP, exhibiting a broad linear response range (R2 = 0.992) from 240 nmol L−1 to 288 μmol L−1 and a low detection limit of 20 nmol L−1. Furthermore, the sensor exhibited good anti-interference for isomers and common distractors in water, excellent stability and reproducibility, and high recovery in actual water samples. Our reported sensor gives a novel strategy for sensitive, selective, and in situ detection of 2,6-DCNP in practical analysis.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CATALYSIS
·
2020
·
IF 7.888
Yingchun Guo,Lei Feng,Changcheng Wu,Xiaomei Wang,Xu Zhang
Rational design and fabrication of metal–organic framework (MOF)-derived ordered hierarchical macro-/meso-/microporous N-doped carbon materials featured with the atomically dispersed metal atoms can effectively enhance their catalytic performance. Herein we develop a template-assisted strategy, namely the confined growth and pyrolysis of single-crystalline zeolite imidazolate framework-8 (ZIF-8) in three-dimensional ordered template voids, to create hierarchical porosity in MOFs-derived N-doped carbon materials. The as-synthesized single-atom Zn on N-doped hierarchically ordered porous carbon polyhedrons (Zn-N-HOPCPs) show integrated Lewis acid (single-atom Zn) and base sites (pyridinic N), high surface area (1128 m 2 ·g −1 ), large pore volume (0.90 cm 3 ·g −1 ), periodically interconnected open windows (~55 nm), highly accessible micro/mesopore channels (0.55, 0.8, 1.2, and 4 nm), and abundant Zn content (5.8 wt%). The hierarchical nanoarchitecture (macro-/meso-/micropores) significantly facilitates mass transfer for bulky-molecule-involved reactions and exposes inside active sites, resulting in satisfactory CO 2 photoconversion under mild conditions. The strategy presented here sheds light on the design and fabrication of various hierarchically ordered porous carbon decorated with atomically dispersed metal atoms for other important applications.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）