MICROCHIMICA ACTA
·
2016
·Vol. 183
·期 12
·3275-3283
·
IF 4.831
Yao Youzhi,Liu Yunchun,Yang Zhousheng
The authors describe a method for room temperature preparation of reduced graphene oxide (rGO) decorated with Ag-Cu nanoparticles (NPs). The nanocomposite (Ag-CuNP/rGO) was characterized by scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy and transmission electron microscopy. A glassy carbon electrode (GCE) modified with this nanocomposite dispersed is shown to be a viable electrode for determination of Sudan I (best at a working voltage of −112 mV vs. Ag/AgCl), with remarkably increased electrochemical response to Sudan I compared to that of a plain GCE. The calibration plot is linear in the 1.0 nM to 10 µM concentration range, with a 0.4 nM detection limit (at a signal-to-noise ratio of 3). The method was successfully applied to the determination of Sudan I in ketchup and chili powder.
The nanocomposite of reduced graphene oxide (rGO) decorated with Ag-Cu nanoparticles (Ag-CuNP/rGO) was prepared using NaBH 4 as a reductant at room temperature. A glassy carbon electrode (GCE) was coated with a Ag-CuNP/rGO nanocomposite to form a modified electrode that can detect trace concentrations of Sudan I.
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Nano Energy
·
2018
·
IF 13.12
Junjie He,Yuren Xiang,Fan Zhang,Jiarong Lian,Rui Hu,Pengju Zeng,Jun Song,Junle Qu
Inorganic NiO is a promising hole extracting material for p-i-n planar perovskite solar cells due to its low cost, ultra-high photo and thermal-stability, and high energy level of conduction band blocking photoelectron from perovskite to cathode to prevent charge recombination at the interface. However, the power conversion efficiency (PCE) of NiO-based p-i-n devices is still lower than TiO 2 based n-i-p devices because of relatively low light harvesting ability in the red light region and the low work function of NiO limited the improvement of open circuit voltage. In this study, a novel surface modification method was developed for NiO-based p-i-n planar devices, which enhanced red light harvesting ability and device open voltage. It proved that all three functional groups of surface modifier played key role to boost the device performance. Detailed investigations show an increased interface contact between perovskite and hole transport layer improving charge extraction, preferential orientation of perovskite crystal that insures external quantum efficiency higher than 90% in the whole visible light range and even up to 95% in short wavelength region. The surface treatment improves the short circuit current density from 20 to 23.6 mA cm -2 and open voltage from 1.06 to 1.12 V.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Xiao Han,Xiujuan Zhong,Fanpeng Meng,Jinsheng Zhao,Jun Yang,Yongfa Zhu,Qian Xu,Jun Hu,Ningqiang Zhang
Building polymer heterojunctions (PHJs) is a promising way to enhance the performance of single-polymer photocatalysts, but it's still challenging to design the ideal structure with well-matched energy levels and strong interface synergy by precisely tuning the molecular structure of polymer. Herein, two triazine-based conjugated porous polymers (CPPs) were synthesized in advance including TB and TR via linkage unit modulation at the molecular level, and then their PHJs with carbon nitride (g-C 3 N 4 ) nanosheet including TB/CN and TR/CN were successfully constructed by the convenient physical ball milling method. Theoretical calculations, electron paramagnetic resonance (EPR), and in situ X-ray absorption near-edge structure (XANES) spectra show that replacing thiophene rings in TR with phenyl rings in TB changes the PHJ structure from type-I (TR/CN) to an S-scheme (TB/CN) heterojunction. Compared to TR/CN, TB/CN exhibits a stronger internal electric field (IEF), better redox ability, longer exciton lifetime, and improved charge separation and transport. As a result, TB (Wang et al., 2023a (20))/CN achieves a much higher hydrogen evolution rate (HER) of 9.11 mmol g −1 h −1 , which is 1.8 times of TR (Wang et al., 2023a (20))/CN and 6.6 times of pure g-C 3 N 4 . TB (Wang et al., 2023a (20))/CN also shows superior Cr(VI) reduction efficiency (98.5 % in 60 min), outperforming TR (Wang et al., 2023a (20))/CN (82.0 %) and g-C 3 N 4 (21.8 %). This study shows that adjusting the linkage units can effectively tune the interface properties of PHJs, offering a promising strategy for designing efficient polymer-based photocatalysts.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Cailing Yu,Xinyu Zu,Yan Liang,Xiangzhong Zhao,Yingqiu Li,Chenying Wang,Hua Wang
Food-derived dual-effect peptides exhibit multi-target therapeutic potential and represent a promising strategy for managing comorbid conditions. However, technical challenges in their purification remain major obstacles to practical application. In this study, a nanofibrous membrane immobilized with angiotensin I-converting enzyme (ACE) and α-amylase (PPA) was developed for the efficient screening of dual-target inhibitory peptides. The immobilized enzymes achieved maximum loading capacities of 1.0466 mg/cm 2 (ACE) and 2.2871 mg/cm 2 (PPA), while retaining specific activities of 0.0173 U/mg and 0.0208 U/mg, respectively. This approach markedly reduced the number of peptide candidates from 1714 to 234, while enhancing their quality, as evidenced by increased inhibitory activities of 21.85 % for ACE and 22.22 % for PPA. Two dual-target inhibitory peptides, YDPR and LPDYR, were successfully isolated from Chlorella protein hydrolysates. Enzyme inhibition assays confirmed their potent inhibitory effects on ACE (YDPR: IC 50 = 89.05 ± 0.90 μM; LPDYR IC 50 = 170.50 ± 0.68 μM) and PPA (YDPR: IC 50 = 76.30 ± 1.05 μM; LPDYR: IC 50 = 112.51 ± 3.19 μM). Molecular dynamics simulations revealed that the dual inhibitory activities of these peptides arise from the formation of stable enzyme-peptide complexes involving key catalytic residues of ACE (Glu384, Tyr523, His353, Ala354, and Glu411) and PPA (His305, Asp300, Asp356, and Trp59). In summary, the high-efficiency screening strategy developed here provides a solid theoretical and technical foundation for the discovery of multi-target inhibitors.
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JOURNAL OF PHYSICAL CHEMISTRY B
·
2025
·
IF 2.9
Pengshuai Zhang,Binbin Wu,Jiaxuan Xu,Yixin Zhang,Qianjin Chen,Ruipeng Bao,Xiaoqiang Lian,Yue Zeng,Chuanmin Song,Yunpeng Shen,Shuoye Yang
In this study, the solid–liquid phase equilibrium data for methimazole (Form I) was measured in three binary solvent mixtures (2-methoxyethanol + butyl acetate, 2-methoxyethanol + isopropyl acetate, 2-ethoxyethanol + ethylene glycol) over a temperature range of 283.15 to 323.15 K under 0.1 MPa using a gravimetric method. The results reveal that in the binary solvents (2-methoxyethanol + butyl acetate, 2-methoxyethanol + isopropyl acetate), the solubility of methimazole increased with increasing mass fraction of 2-methoxyethanol. For the solvent of 2-ethoxyethanol + ethylene glycol, due to cosolvency effects, the mole fraction solubility of methimazole reached its maximum value (0.2914) when the mass fraction of 2-ethoxyethanol was 0.70 at 323.15 K. The solubility data was correlated using the Jouyban-van’t Hoff, Jouyban-Apelblat, GSM and λh model. The reliability of these thermodynamic models was assessed by the average relative deviation (ARD) and the root-mean-square deviation (RMSD). Additionally, the applicability of the four thermodynamic models was evaluated using the Akaike Information Criterion (AIC). The calculated minimum RMSD and ARD values are 0.000729 (λh model) and 0.0027 (GSM model), respectively. The minimum AIC value for the four models selected is −3348.62 (GSM model). These results indicate that the GSM model correlates the solubility of methimazole better than the other three models. Powder X-ray diffraction (PXRD) and differential scanning calorimetry (DSC) characterization analysis showed that the crystal morphology of methimazole remains stable before and after the dissolution of methimazole in the three binary solvent systems. In addition, the solute–solvent interaction effect was assessed using Hansen solubility parameters (HSPs). The distribution of surface charge on methimazole was examined through the molecular electrostatic potential surface (MESP) analysis. Furthermore, molecular dynamics simulations were employed to investigate the interactions between solute and solvent molecules via the radial distribution function (RDF). Finally, the standard apparent thermodynamic properties of methimazole in the selected solvents were evaluated, and the results showed that the dissolution of methimazole in this work was an endothermic and entropy increase process.
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TALANTA
·
2016
·
IF 4.035
Bei Hua Kang,Zhong Feng Gao,Na Li,Yan Shi,Nian Bing Li,Hong Qun Luo
Silver ions have been widely applied to many fields and have harmful effects on environments and human health. Herein, a label-free optical sensor for Ag + detection is constructed based on thiazole orange (TO) as a fluorescent probe for the recognition of i-motif DNA structure change at neutral pH. Ag + can fold a C-rich single stranded DNA sequence into i-motif DNA structure at neutral pH and that folding is reversible by chelation with cysteine (Cys). The DNA folding process can be indicated by the fluorescence change of TO, which is non-fluorescent in free molecule state and emits strong fluorescence after the incorporation with i-motif DNA. Thus, a rapid, sensitive, and selective method for the detection of Ag + and Cys is developed with a detection limit of 17 and 280 nM, respectively. It is worth noting that the mechanism underlying the increase of the fluorescence of thiazole orange in the presence of i-motif structure is explained. Moreover, a fluorescent DNA logic gate is successfully designed based on the Ag + /Cys-mediated reversible fluorescence changes. The proposed detection strategy is label-free and economical. In addition, this system shows a great promise for i-motif/TO complex to analyze Ag + in the real samples.
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DYES AND PIGMENTS
·
2025
·
IF 4.2
Shanting Liu,Xi Kang,Bumeng Guo,Zewei Song,Shuang Li,Yinghan Li,Sheng Hua Liu,Zhao Chen
Due to their distinctive stimulus-responsive properties, materials exhibiting hypsochromic mechanofluorochromism (MFC) or force-induced substantial weakening of fluorescence intensity have demonstrated remarkable application potential in the field of information security. This study designed and synthesized two novel fluorene-based dinuclear gold(I) complexes, 1 and 2 . Both molecules exhibited aggregation-induced emission (AIE) characteristics. Specifically, complex 1 showed reversible hypsochromic MFC. In contrast, complex 2 exhibited force-induced substantial weakening of fluorescence intensity. It is worth noting that 2 is the first example of gold(I)-based luminogen capable of simultaneously exhibiting AIE and force-induced substantial weakening of fluorescence intensity. Based on the force-induced significant fluorescence attenuation feature of luminogenic complex 2 , an interesting information anticounterfeiting system involving a pizza model was successfully established. This work not only reports the first example of AIE-active gold(I) complex featuring anisotropic mechanical force-induced pronounced fluorescence reduction but also provides a valuable reference for anticounterfeit applications of mechanically responsive luminogens.
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JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Junlei Zhang,Wei Zhao,Shanshan Wu,Renli Yin,Mingshan Zhu
Advanced oxidation processes (AOPs) based on heterogeneous catalytic activated peroxymonosulfate (PMS) have been becoming alternatives to conventional wastewater treatment technologies to directly degrade chemical contaminants. To build dual/multi redox cycles of different metal ions may be an effective means for better PMS activation. Herein, this study designed Mn 3 O 4 /CuBi 2 O 4 with dual redox cycles of Mn(III)/Mn(IV) and Cu(I)/Cu(II) to activate PMS for efficiently decomposing and mineralizing diclofenac sodium (DCF). Under optimal reaction conditions, DCF (50 mg/L) was degraded totally within 10 min, and TOC removal rate reached up to 74.3%. The possible mechanism of PMS activation by Mn 3 O 4 /CuBi 2 O 4 was proposed, wherein dual redox cycles of Mn(III)/Mn(IV) and Cu(I)/Cu(II) on Mn 3 O 4 /CuBi 2 O 4 effectively facilitated PMS activation to generate · O 2 − , 1 O 2 , SO 4 · − and · OH, which was responsible for DCF degradation. Moreover, combined with degraded products detected by high resolution liquid chromatography coupled to mass spectrometry and corresponding toxic assessment results, the possible degradation pathways of DCF were proposed and the relative toxicity of degraded products was evaluated. This work may be useful for developing stronger heterogeneous activators of PMS to construct more efficient AOPs for purifying wastewater.
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Advanced Science
·
2023
·Vol. 10
·期 13
·2207630
·
IF 15.1
Wen-Fa Chen,Bin-Wen Liu,Shao-Min Pei,Xiao-Ming Jiang,Guo-Cong Guo
In contrast to anionic group theory of nonlinear optical (NLO) materials that second-harmonic generation (SHG) responses mainly originate from anionic groups, structural regulation on the cationic groups of salt-inclusion chalcogenides (SICs) is performed to make them also contribute to the NLO effects. Herein, the stereochemically active lone–electron-pair Pb 2+ cation is first introduced to the cationic groups of NLO SICs, and the resultant [K 2 PbX][Ga 7 S 12 ] (X = Cl, Br, I) are isolated via solid-state method. The features of their three-dimensional structures comprise highly oriented [Ga 7 S 12 ] 3− and [K 2 PbX] 3+ frameworks derived from AgGaS 2 , which display the largest phase-matching SHG intensities (2.5−2.7 × AgGaS 2 @1800 nm) among all SICs. Concurrently, three compounds manifest band gap values of 2.54, 2.49, and 2.41 eV (exceeding the criterion of 2.33 eV), which can avoid two-photon absorption under the fundamental laser of 1064 nm, along with the relatively low anisotropy of thermal expansion coefficients, leading to improved laser-induced damage thresholds (LIDTs) values of 2.3, 3.8, and 4.0 times that of AgGaS 2 . In addition, the density of states and SHG coefficient calculations demonstrate that the Pb 2+ cations narrow the band gaps and benefit SHG responses.
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MOLECULES
·
2026
·Vol. 31
·期 20
·3615
·
IF 5.1
Haoyu Jia,Tong Yan,Luran Wang,Lingling Song
Icariside I is a pharmacologically important prenylated flavonoid glycoside, yet its efficient biocatalytic production from icariin is hindered by the limited stability and recyclability of the enzymes involved. In this study, an α-L-rhamnosidase mutant R783A (Rha R783A) was heterologously expressed, purified, and immobilized within a Cu-based metal–organic framework (MOF) via a one-pot co-precipitation strategy. The resulting Rha R783A@MOF biocomposite exhibited enhanced stability compared to the free enzyme, retaining >90% residual activity after incubation at 60 °C for 2 h and 86.4% after 30 days of storage. It also demonstrated broad pH adaptability. In the biotransformation of icariin, Rha R783A@MOF achieved a 99.8% conversion rate and a 97.8% yield of icariside I. Furthermore, the biocomposite maintained an 88.9% yield after eight consecutive reuse cycles under high-temperature conditions (60 °C), demonstrating excellent operational stability. This work presents a robust and sustainable strategy for icariside I production, highlighting the potential of MOF microparticles as an effective platform for the biocatalytic synthesis of high-value flavonoid compounds.
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APPLIED SURFACE SCIENCE
·
2026
·
IF 6.6
Xiangchen Kong,Xuyang Dong,Shijie Hong,Kaiyue Wang,Yuming Tian
Photocatalytic water splitting for hydrogen production is a key approach to addressing the energy crisis. However, Type-I heterojunctions are limited by issues such as low photogenerated carrier separation efficiency, weak intrinsic electric fields at the interface, and a scarcity of active sites on the surface. To address these issues, this study proposes a synergistic strategy combining “interface electric field engineering” and “surface molecular engineering”: A 2D/2D CeO 2 /SnSe heterojunction is first constructed via a stepwise hydrothermal method. Subsequently, ammonium hexachlorostannate(IV) ([SnCl 6 ] 2- ) is introduced onto the heterojunction surface via electrostatic adsorption. After subsequent drying, these complexes undergo conversion to form Sn-O-Ce bonds at the interface, achieving “molecular welding” and enhancing interfacial coupling. Kelvin probe force microscopy (KPFM) and electron paramagnetic resonance (EPR) measurements confirm the successful establishment of the built-in interfacial electric field. Density functional theory (DFT) calculations further reveal that this built-in electric field drives photogenerated electrons from SnSe across the interface and into the more negative conduction band of CeO 2 , enabling the composite material, which originally exhibited Type-I band alignment, to achieve a Type-II-like charge separation pathway under illumination. Photocatalytic hydrogen evolution tests indicate that the hydrogen evolution rate of the optimized material has increased twenty-fold. This work provides both experimental and theoretical grounds for the regulation of the band structure of heterojunctions through interfacial chemical engineering, as well as for the development of highly efficient photocatalysts. Download: Download high-res image (186KB) Download: Download full-size image
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CARBOHYDRATE POLYMERS
·
2025
·
IF 12.5
Jinyan Gu,Mouming Zhao,Lijun You,Lianzhu Lin
The colon immune activity of high branched rhamnogalacturonan-I type pectin from Lycium barbarum fruit (LBP-P4) was unclear. This study comparatively investigated the colon immunity activity of LBP-P4 and inulin and explored its mechanism via simulated colon biological and mechanical barriers models. LBP-P4 could be slowly degraded and utilized by intestinal microorganisms with degradation rate of 88.88 %. Meanwhile, LBP-P4 increased the relative abundance of Bifidobacterium, especially Bifidobacterium longum subsp. longum , which was confirmed by single Bifidobacterium fermentation. In the normal colon mechanical barrier coupled with macrophage model, the colonic metabolites of LBP-P4 enhanced macrophage viability and phagocytic ability. In the damaged colon mechanical barrier coupled with macrophage model, the colonic metabolites of LBP-P4 enhanced mechanical barrier integrity, reduced the production of NO and IL-6 and improved macrophage viability and phagocytic ability. The colon immunity activity of LBP-P4 was stronger than that of inulin, which was because the contents of immunity related metabolites i.e. short chain fatty acids and tryptophan metabolites, were significantly higher (about 1–3 fold) in LBP-P4 group than those in inulin group. Our findings provided new insights into the probiotic and intestinal immunity function of LBP-P4 and offered theoretical basis for the development of functional products of LBP-P4.
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