JOURNAL OF CHEMICAL THERMODYNAMICS
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2017
·
IF 2.726
Hui Ding,Wenjing Ke,Dan Zhao,Lulu Wang,Yujie Gao,Shejiang Liu
In this work, we measured the isobaric vapor-liquid equilibrium (VLE) data for the binary system of methyl caprate (1) + methyl laurate (2) at 2,4 and 6 kPa with a modified Othmer still. The point consistency test of Van Ness test method was applied to check the thermodynamic consistency of all the experimental values, which guaranteed the reliability of our measurements. Afterwards, the experimental data were regressed by two activity coefficient models (Wilson, NRTL). Furthermore, we made the data prediction with the group contribution method (UNIFAC) and the COSMO-SAC model. The results of all the regressions and predictions are satisfying and reasonable, while the results provided by the NRTL model are relatively better than the other three models, with the root mean square deviations of temperature and vapor-phase mole fraction less than 0.33 K and 0.0069, respectively.
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CANADIAN JOURNAL OF CHEMICAL ENGINEERING
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2017
·Vol. 96
·期 3
·679-687
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IF 1.356
Zhongrui Liang,Lichao He,Wenchao Wang,Zhiyong Zhou,Zhongqi Ren
Tuberculosis is a serious bacterial infection in developing countries, especially in areas with drug resistance. The development of the anti-tuberculosis drug ethionamide (ETA) is therefore particularly important. We have designed a new route for ETA synthesis and considered the drug's amenability to large-scale manufacture. We evaluated different routes for the synthesis of ETA and selected the most suitable process for the industrial production of this material, which involved the Minisci reaction of 4-cyanopyridine with propionic acid using a AgNO 3 /(NH 4 ) 2 S 2 O 8 catalyst system under acidic conditions. The effects of different parameters on the reaction were studied, and the production of the intermediate of 2-ethyl-4-cyanopyridine was twice recrystallized from methanol to obtain pure ETA. In the Minisci reaction, the system was stirred for an additional 20 min at 80 °C after the addition of ammonium persulphate solution. The subsequent formation of thioamide was conducted at 40 °C to 60 °C for 1.5 h with a 1:5:2 molar ratio of 4-cyanopyridine, propionic acid, and ammonium sulphide. The purity of the crude ETA reached 98.77 % after two recrystallization steps. This process could be scaled up on a much larger scale (1 kg), leading to the yield of alkylation reaction and overall yield of the production process as 44.06 % and 31.26 %, respectively.
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JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
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2015
·Vol. 53
·期 21
·2469-2480
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IF 3.113
Yong Deng,Xi Wang,Qiulin Yuan,Mengxiang Zhu,Ying Ling,Haoyu Tang
A series of side-chain-functionalized α-helical polypeptides, i.e., poly(γ-4-(3-chloropropoxycarbonyl)benzyl- L -glutamate) (6) have been prepared from n-butylamine initiated ring-opening polymerization (ROP) of γ-4-(3-chloropropoxycarbonyl)benzyl- L -glutamic acid-based N -carboxyanhydride. Polypeptides bearing oligo-ethylene-glycol (OEG) groups or 1-butylimidazolium salts were prepared from 6 via copper-mediated [2+3] alkyne-azide 1,3-dipolar cycloaddition or nuleophilic substitution, respectively. CD and FTIR analysis revealed that the polymers adopt α-helical conformations both in solution and the solid state. Polymers bearing OEG (m = 3) side-chains showed reversible LCST-type phase transition behaviors in water while polymers bearing 1-butylimidazolium and I − counter-anions exhibited reversible UCST-type transitions in water. Variable-temperature UV-vis analysis revealed that the phase transition temperatures ( T pt s) were dependent on the main-chain length and polymeric concentration. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015 , 53 , 2469–2480
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ACS Nano
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2013
·
IF 12.062
Feng-Jia Fan,Liang Wu,Ming Gong,Guangyao Liu,Yi-Xiu Wang,Shu-Hong Yu,Shiyou Chen,Lin-Wang Wang,Xin-Gao Gong
The wurtzite-derived Cu2ZnSn(S1–xSex)4 alloys are studied for the first time through combining theoretical calculations and experimental characterizations. Ab initio calculations predict that wurtzite-derived Cu2ZnSnS4 and Cu2ZnSnSe4 are highly miscible, and the band gaps of the mixed-anion alloys can be linearly tuned from 1.0 to 1.5 eV through changing the composition parameter x from 0 to 1. A synthetic procedure for the wurtzite-derived Cu2ZnSn(S1–xSex)4 alloy nanocrystals with tunable compositions has been developed. A linear tunable band-gap range of 0.5 eV is observed in the synthesized alloy nanocrystals, which shows good agreement with the ab initio calculations.
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
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2012
·
IF 5.625
Weiming Wu,Linrui Wen,Lijuan Shen,Ruowen Liang,Rusheng Yuan,Ling Wu
Photoreduction of 4-nitroaniline to p -phenylenediamine over TiO 2 , ZnO, PbBi 2 Nb 2 O 9 and CdS photocatalysts in the presence of CH 3 OH was investigated under light irradiation ( hv ≥ band gap) upon purging with N 2 . Compared with PbBi 2 Nb 2 O 9 and CdS, TiO 2 and ZnO showed photocatalytic activities for the photoreduction of 4-nitroaniline. Electron spin resonance analysis results revealed that a methanol radical could be detected in the present of TiO 2 and ZnO. Its formation was attributed to the reaction between the hydroxyl radical and CH 3 OH molecule. The species had strong reductive ability, and therefore could reduce 4-nitroaniline to p -phenylenediamine. Other alcohols (C 2 H 5 OH and i -C 3 H 7 OH) were also found to be efficient additives for the photoreduction of 4-nitroaniline. The results of the 2 H-labeled experiments indicated that the p -phenylenediamine formation was formed by the hydrogen transfer reaction between the 4-nitroaniline and H 2 O molecules. A mechanism was proposed to explain the photoreduction of 4-nitroaniline to p -phenylenediamine in the present alcohols.
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FLUID PHASE EQUILIBRIA
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2015
·
IF 2.2
Hao Wu,Jing Zhu,Yiwei Wang,Chengwei Chang,Junsu Jin
To understand the phase behavior of 3-hydroxybenzaldehyde (3-HBA) and the solubility effect of 3-HBA and 4-hydroxybenzaldehyde (4-HBA) on each other in supercritical carbon dioxide (SCCO 2 ), the equilibrium solubility of 3-HBA and its mixture with 4-HBA, was measured in SCCO 2 binary system (comprising of a solute and SCCO 2 ) and ternary system (comprising of two solutes and SCCO 2 ) at temperature and pressure given in range of 308–328 K and 11.0–21.0 MPa respectively. Comparing the solubility of 3-HBA and 4-HBA between in the binary system and ternary system, it was found that the equilibrium solubility of both 3-HBA and 4-HBA was enhanced in the ternary system due to the molecular interaction. The experimental data were correlated by Chrastil, Mendez-Santiago and Teja (M-S-T), Sovova, their modified models, and Zhu et al. model. Also a new model was deduced and established based on the Chemistry Association Theory and was verified by 636 groups of solubility data. The correlated results indicated that the new model obtained a less deviation than other models, including the modified Chrastil model, the modified M-S-T model, the modified Sovova model, and Zhu et al. model, all of which have same adjustable parameters.
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JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
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2015
·
IF 2.729
Hongjuan Li,Ying Liu,Haizhu Jin,Sujing Liu,Shengtao Fang,Chunhua Wang,Chuanhai Xia
Vitexin-4″- O -glucoside and vitexin-2″- O -rhamnoside are the major flavonoids of hawthorn leaves. In this work, the adsorption and desorption characteristics of vitexin-4″- O -glucoside and vitexin-2″- O -rhamnoside on seven macroporous resins were evaluated. Among the tested resins, the HPD-400 resin showed the best adsorption and desorption capacities. Adsorption isotherms were constructed for the HPD-400 resin and well fitted to Langmuir and Freundlich models. Dynamic adsorption and desorption tests were performed on column packed with the HPD-400 resin to optimize the chromatographic parameters. After one run treatment with the HPD-400 resin, the contents of vitexin-4″- O -glucoside and vitexin-2″- O -rhamnoside in the product were increased 8.44-fold and 8.43-fold from 0.720% and 2.63% to 6.08% and 22.2% with recovery yields of 79.1% and 81.2%, respectively. These results show that the developed method is a promising basis for the large-scale purification of vitexin-4″- O -glucoside and vitexin-2″- O -rhamnoside from hawthorn leaves and other plant materials.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2015
·
IF 4.097
Fen-Ying Kong,Sai-Xi Gu,Jing-Yi Wang,Hai-Lin Fang,Wei Wang
We demonstrate herein a newly developed electrochemical sensor base on the reduced graphene oxide–titanium nitride (RGO–TiN) nanohybrid . The nanohybrid was prepared by mixing the TiN nanoparticles and GO dispersion and then treating with glucose and Zn foils. The morphologies and microstructures of the as-prepared nanohybrid were characterized by UV–vis absorption spectroscopy, X-ray photoelectron spectroscopy, transmission electron microscopy and Raman spectroscopy. The as-prepared RGO–TiN nanohybrid exhibited excellent electrocatalytic activity toward the simultaneous detection of acetaminophen (ACOP) and 4-aminophenol (4-AP). As a result, the linear detection ranges were 0.06–660 μM for ACOP and 0.05–520 μM for 4-AP, respectively, with the low detection limits of 0.02 μM for ACOP and 0.013 μM for 4-AP. Based on the excellent performance, it was demonstrated that the prepared RGO–TiN nanohybrid was a promising candidate for advanced electrode material in electrochemical sensing field and the as-prepared RGO–TiN nanohybrid may find more applications for the detection of various analytes.
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ACS Applied Materials & Interfaces
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2013
·
IF 5.008
Shi Peng,Qiang Zheng,Xin Zhang,Linghui Dai,Jingxian Zhu,Yanbin Pi,Xiaoqing Hu,Wenqing Cheng,Chunyan Zhou,Yinlin Sha,Yingfang Ao
A disintegrin and metalloproteinase with thrombospondin motif-4 (ADAMTS-4) plays a pivotal role in degrading aggrecan, which is an early event in cartilage degrading joint diseases such as osteoarthritis (OA). Detection of ADAMTS-4 activity could provide useful clinical information for early diagnosis of such diseases and disease-modifying therapy. Therefore, we developed a ADAMTS-4 detective fluorescent turn-on AuNP probe (ADAMTS-4-D-Au probe) by conjugating gold nanoparticles with a FITC-modified ADAMTS-4-specific peptide (DVQEFRGVTAVIR). When the ADAMTS-4-D-Au probe was incubated with ADAMTS-4, the fluorescence recovered and fluorescence intensity markedly increased in proportion to concentrations of ADAMTS-4 and the probe. A nearly 3-fold increase in fluorescent intensity in response to only 3.9 pM of ADAMTS-4 was detected, whereas almost no fluorescence recovery was observed when the probe was incubated with matrix metalloproteinase (MMP)-1, -3, and -13. These results indicate a relative high sensitivity and specificity of the probe. Moreover, ADAMTS-4-D-Au probe was used to detect ADAMTS-4 activity in synovial fluid from 11 knee surgery patients. A substantial increase in fluorescent intensity was observed in the acute joint injury group as compared to the chronic joint injury and end-stage OA groups, indicating that this simple and low-cost sensing system might serve as a new detection method for ADAMTS-4 activity in biological samples and in screens for inhibitors for ADAMTS-4-related joint diseases. Additionally, this probe could be a potential biomarker for early diagnosis of cartilage-degrading joint diseases.
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高影响因子
HYDROMETALLURGY
·
2014
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IF 2.224
Mohannad Mayyas,Mohammad Al-Harahsheh,Xian-Yong Wei
Jordanian phosphate ore contains 70–150 parts per million (ppm) uranium. The uranium in the ore tends to dissolve during the leaching of phosphate ore with sulfuric acid to produce phosphoric acid (PA). Solvent extraction (SX) using various extracting agents is widely used to extract uranium from PA. Meanwhile, much research work has been carried out to develop suitable solid phase extractants in order to reduce cost and enhance efficiency. In this study, a new solid phase extractant has been synthesized by anchoring 2-hydroxy-4-aminotriazine onto activated carbon (ACH). The extraction of uranium from Jordanian PA using ACH and the synergistic mixture of di-ethylhexyl phosphoric acid and trioctyl phosphine oxide (DEPA–TOPO) diluted in kerosene were investigated and the performance of each extractant was evaluated and compared. The results showed that 91% extraction and 559.9 ppm loading capacity were achieved after 2 to 3 min mixing time using 0.5 M DEPA–0.125 M TOPO at 20 °C, 410 mV and 1/1 phase ratio. The activation energy ( E a ) of the solvent extraction (− 26.03 kJ mol − 1 ), calculated from Arrhenius plot, indicates that the reaction is barrier-less and exothermic in nature. On the other hand, uranium sorption onto ACH reaches equilibrium after 10 min and about 92% extraction can be achieved at 20 °C, C o = 70 mg/l, V = 200 ml, W = 100 mg and 410 mV; the rate constant for the uranium sorption onto ACH (16.54 × 10 − 3 g mg − 1 min − 1 ) was calculated from the pseudo-second order equation. The countercurrent extraction results showed that ACH has high physical, chemical stability and loading capacity about 618 mg g − 1 . Thermodynamic parameters ( ΔH ads ° = 20.61 kJ mol − 1 , ΔS ads ° = 160.47 J mol − 1 K − 1 , ΔG ads ° (333.3 K) = − 32.87 kJ mol − 1 ) suggest that the adsorption is endothermic and spontaneous in nature, which confirm the feasibility of the process.
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POLYMER COMPOSITES
·
2014
·Vol. 36
·期 9
·1597-1605
·
IF 1.455
Ruxangul Jamal,Ahmat Ali,Li Zhang,Yakupjan Osman,Adalet Rahman,Tursun Abdiryim
Poly(3′,4′-ethylenedioxy-2,2′:5′,2″-terthiophene)/ZnO(poly(TET)/ZnO) composites with the ratio of poly(TET) and nano-ZnO from 3:1 to 1:3 were synthesized by hand grinding and ball milling methods, respectively. The photocatalytic activities of the composites were examined through the degradation processes of methylene blue (MB) solution under UV light irradiation, and the possible mechanism for the photocatalytic activity enhancement by synergetic effects between nano-ZnO and poly(TET) was proposed. The results showed that the strong interactions between the poly(TET) and nano-ZnO occurred in the case of ball milling method. The results also proved that the crystallinity of ZnO was not disturbed in both of methods, and the nano-ZnO was uniformly distributed in polymer matrix in the case of ball milling method. The comparative studies showed that the addition of the nano-ZnO could enhance the photocatalytic activities of the composites. The highest degradation efficiency (100%) at 3 h under UV light irradiation occurred in the case of poly(TET)/ZnO(1:1) synthesized by ball milling method. Furthermore, the nanocompsosite displayed higher photocatalytic activity than nano-ZnO, which was due to the holes ( h + ) transferring from the valence band of ZnO to the polymer backbone and the adsorption of MB molecules in polymer matrix via π–π conjugation between MB and aromatic regions of the poly(TET). POLYM. COMPOS., 36:1597–1605, 2015. © 2014 Society of Plastics Engineers
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Journal of the Taiwan Institute of Chemical Engineers
·
2014
·
IF 2.637
Wan-Qian Guo,Shuang Guo,Ren-Li Yin,Yuan Yuan,Nan-Qi Ren,Ai-Jie Wang,Dong-Xu Qu
In this study, the enhancement on 4-chloronitrobenzene (4-CNB) reduction was investigated in a dual-bioelectrochemical system with the cathode seeded by enriched 4-CNB degradation inoculums. We demonstrated that the biocathode had the ability to promote 4-CNB reduction and avoid more reluctant byproducts production. At room temperature, when initial 4-CNB concentration was 20 mg/L with 0.5 V external voltage, the 4-CNB removal efficiency reached 93.7%, while in the abiotic reactor and anaerobic bioreactor reduction rate were 62.9% and 88.4%, respectively. The 4-CNB was mainly converted to 4-CAN ( para -chloroaniline). Some of the 4-CAN could be dechlorinated and form aniline (AN), which was more degradable by microorganism. The biodiversity was richer based on the result of scanning electron microscope. Results also showed that the present used reactor was feasible to simplify pollutant transformation and improve transformation efficiency compared with the single abiotic cathode and anaerobic reactor . The bioelectrochemical reactor cathode provided a promising condition for pollutants reduction.
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