JOURNAL OF CRYSTAL GROWTH
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2012
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IF 1.726
Shenjie Li,Daocheng Pan
Cu 2 SnSe 3 nanocrystals with a metastable zincblende and wurtzite structure have been successfully synthesized. The crystal structures were confirmed by means of X-ray diffraction and selected area electron diffraction . The lattice mismatch between Cu 2 SnSe 3 and ZnSe is only 0.26%, thus homogeneously alloyed (ZnSe) x (Cu 2 SnSe 3 ) 1− x nanocrystals could be synthesized. The band gaps of nanocrystals can be tuned in a wide range of 2.75 to 0.92 eV; however the bowing parameter as high as 19.1 eV for alloyed (ZnSe) x (Cu 2 SnSe 3 ) 1− x nanocrystals was observed. These low cost and dispersible alloyed (ZnSe) x (Cu 2 SnSe 3 ) 1− x nanocrystals with a targeted band gap have a high potential in thin film solar cells.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2012
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IF 2.237
Rulong Li,Huabin Xing,Qiwei Yang,Xu Zhao,Baogen Su,Zongbi Bao,Yiwen Yang,Qilong Ren
This paper presents an extensive study on the feasibility of ionic liquids (ILs) for the extractive separation of a 1-hexene/n-hexane mixture. Seventeen ILs were tested at 313 K. The extraction selectivities of 1-hexene to n-hexane were in the range 1.5–3.0. The chemical structures of anion and cation in ILs greatly affected the extraction, and the functional groups, such as carbon–carbon double bond, nitrile, ester, and amide, in the ILs led to higher selectivities. The increase of alkyl chain length in cation led to the increase of extraction capacity of 1-hexene. To increase the distribution of 1-hexene in IL phase, silver salt was added to the ILs. It was found that ILs containing silver salt had a high distribution of 1-hexene, as well as high selectivity of 1-hexene against n-hexane. The extraction efficiency increased with the concentration of silver salt in ILs. When the initial feed concentration of 1-hexene was smaller, the selectivity of 1-hexene to n-hexane was higher. A simple mathematical model has been developed to describe the total 1-hexene content in the reaction media under study, on the basis of the formation of complexes between silver and 1-hexene with different stoichiometry. This work proves that the ILs can act as effective extractants in 1-hexene/n-hexane separation.
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JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2011
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IF 2.089
Baimei Yang,Hui Wan,Guofeng Guan
Isobaric binary vapor–liquid equilibrium (VLE) data for 1-butanol + ethylbenzene, or o-, or m-, or p-xylene and isobaric quinary VLE data for 1-butanol + ethylbenzene + o-xylene + m-xylene + p-xylene are measured at 101.33 kPa using a modified Rose cell with circulation of both phases. The four binary systems of 1-butanol + ethylbenzene, or o-, or m-, or p-xylene exhibit minimum boiling azeotropes, and the composition of the azeotropes are reported. The VLE data for the four binary systems are checked to meet rigorous thermodynamic consistency by Herington method and the point-to-point test of the Fredenslund method. The nonideality in vapor phase of the measured binary systems is analyzed through calculating fugacity coefficients. Combined with the Hayden–O'Connell (HOC) equation, the VLE data for 1-butanol + ethylbenzene, or o-, or m-, or p-xylene are well-correlated by the nonrandom two-liquid (NRTL), universal quasichemical activity coefficient (UNIQUAC), and Wilson equations. The NRTL model parameters obtained from correlation are used to predict the VLE data of the quinary system. According to the average absolute deviation values, the obtained quinary predicted values are in good agreement with the experimental values.
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JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
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2024
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IF 3
Zhang Cong,Guo Yan,Xiao Libai,Gao Hongxu,Zhao Fengqi,Huang Jie,Lü Xingqiang,Ma Haixia
Three 4-(1 H -tetrazole-5-yl-amino)-1,2,4,5-tetrazine-1-one (TATzO) metal salts, K 2 (TATzO)(H 2 O) ( 1 ) and Mg(TATzO)(H 2 O) 6 ·2H 2 O ( 2 ) and Sr(TATzO)(H 2 O) 4 ( 3 ), were synthesized and characterized using Fourier transform infrared (FTIR), elemental analysis, single-crystal X-ray diffraction, and powder X-ray diffraction patterns. The crystal structure and hydrogen bonding interactions have been analyzed. It turns out that 1 and 3 crystallize into a three-dimensional topological network and have strong π – π stacking and hydrogen bonding interactions. Furthermore, the geometric optimization of 1 – 3 was performed using B3LYP-D3/def2svp in Gaussian 16 software package and then analyzed by reduced density gradient. The thermal behavior was conducted using differential scanning calorimetry and thermogravimetric (TG). The decomposition temperature of the three complexes exceeds 250 °C, much higher than that of TATzO (230 °C). The thermal decomposition products of 1 were further studied using thermogravimetric-Fourier transform infrared-mass spectrometry (TG/FTIR/MS). The impact sensitivity test indicated that making complexes can help decrease the sensitivity of the original energetic ligand. Graphical abstract
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Soft Matter
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2011
·Vol. 7
·期 11
·5200-5207
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IF 4.457
Xi-Lian Wei,Zeng-Bin Wei,Xiu-Hong Wang,Zhong-Ni Wang,De-Zhi Sun,Jie Liu,Huai Hua Zhao
The aqueous mixtures of an anionic surfactant (sodium dodecyl benzene sulfonate, SDBS) and an ionic liquid (1-butyl-3-methylimidazolium tetrafluoroborate, [Bmim]BF4) within a certain range of compositions can spontaneously separate into two immiscible aqueous phases (ATPS): one surfactant-rich and the other ionic liquid-rich. The phase diagrams of the ternary system of the SDBS/[Bmim]BF4/water were drawn based on experimental data determined at 10.0, 20.0 and 30.0 °C, respectively. The borderlines of the different specific regions in the diagrams were determined using turbidity titration method. The narrow two-phase region aqueous were found to be close to the water - [Bmim]BF4 side. The formation conditions, compositions, and physicochemical properties of the aqueous two phases have been studied. The effects of temperature, surfactant and ionic liquid content on the phase separation time and phase volume ratio of the ATPS were also investigated. This phase separation phenomenon was found to be likely due to the existence of micelle aggregates with quite large size obtained by Transmission Electron Microscopy (TEM) and Steady-state Fluorescence Quenching Measurements (SFQM) methods.
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CHEMICAL ENGINEERING SCIENCE
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2024
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IF 4.1
Lei Wu,Menghan Liu,Yuting Chen,Ming Li,Tingting Yin,Cong Ma,Wei Fan
UF is widely used as a wastewater treatment and recycling technology. However, membrane fouling is still an important factor affecting the wide application. In this study, APIm with positive amino group was adsorbed to the surface of the carboxylated polyacrylonitrile (PAN) membrane by electrostatic force to reduce the fouling of sodium alginate (SA) caused by Ca 2+ . The results show that 1 v/v% APIm was selected as the optimal dosage, accompanied by the highest water flux of 330.5 L·m -2 h −1 bar −1 and bovine serum albumin (BSA) rejection rate of 91.0 %. When the concentration of Ca 2+ was increased to 10 mM, the Ca 2+ catch amount increased to 48.25 mg/cm 2 . The main anti-fouling mechanism was that APIm captured a certain amount of Ca 2+ in situ, destroyed the complex structure of sodium alginate (SA) and Ca 2+ . Then the fouling layer was easy to be removed by physical cleaning. At the concentration of 10 mM Ca 2+ , the membrane flux recovery rate of 1 v/v% APIm membrane was increased to 80.1 %. This study demonstrates a fouling control strategy for in-situ removal of Ca 2+ bound SA fouling, providing a new approach for the future development of UF membrane.
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Environmental Science & Technology Letters
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2017
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IF 5.308
Jun-Cheng Han,Guo-Jun Chen,Li-Ping Qin,Yang Mu
Cr isotope fractionation during microbial reduction processes is commonly recognized as a promising tool in biogeochemistry and bioremediation. However, the mechanism of Cr isotope fractionation during microbial reduction is poorly understood. In this work, the relationship between the bacterial respiratory pathway and Cr isotope fractionation was investigated in Shewanella oneidensis MR-1. For comparison with the wild type, a mutant strain (ΔomcA/ΔmtrC) with a deficiency in extracellular Cr(VI) reduction was constructed by deleting the omcA and mtrC genes, which encode the terminal reductase during extracellular reduction. The magnitudes of Cr isotope fractionation (ε) for Cr(VI) reduction by the wild type and ΔomcA/ΔmtrC were −2.42 ± 0.68‰ and −2.70 ± 0.22‰, respectively. Surprisingly, the ε values were not significantly different between the two strains. This suggests that isotope fractionation is independent of the metal respiratory pathway during Cr(VI) reduction by S. oneidensis MR-1. Moreover, a three-step Cr isotope fractionation model that includes uptake, reduction, and efflux was proposed to exist during intracellular Cr(VI) reduction by S. oneidensis MR-1. The developed model provides a better understanding of Cr isotope fractionation during microbial reduction.
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Frontiers in Molecular Neuroscience
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2017
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IF 5.076
Li Yun,Wang Shen,Li Tianzhi,Zhu Le,Xu Yuanyuan,Ma Cong
The Ca2+ sensor synaptotagmin-1 (Syt1) plays an essential function in synaptic exocytosis. Recently, Syt1 has been implicated in synaptic vesicle priming, a maturation step prior to Ca2+-triggered membrane fusion that is believed to involve formation of the ternary SNARE complex and require priming proteins Munc18-1 and Munc13-1. However, the mechanisms of Syt1 in synaptic vesicle priming are still unclear. In this study, we found that Syt1 stimulates the transition from the Munc18-1/syntaxin-1 complex to the ternary SNARE complex catalyzed by Munc13-1. This stimulation can be further enhanced in a membrane-containing environment. Further, we showed that Syt1, together with Munc18-1 and Munc13-1, stimulates trans ternary SNARE complex formation on membranes in a manner resistant to disassembly factors NSF and α-SNAP. Disruption of a proposed Syt1/SNARE binding interface strongly abrogated the stimulation function of Syt1. Our results suggest that binding of Syt1 to an intermediate SNARE assembly with Munc18-1 and Munc13-1 is critical for the stimulation function of Syt1 in ternary SNARE complex formation, and this stimulation may underlie the priming function of Syt1 in synaptic exocytosis.
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高影响因子
JOURNAL OF PATHOLOGY
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2025
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IF 5.2
Fang Liu,Qingchun Liang,Li Li,Yuan Gong,Mingxi Li,Liyun Feng,An Chen,Yuanzhi Ye,Zirong Lan,Yining Li,Jing-Song Ou,Lihe Lu,Jianyun Yan
Vascular calcification is an important risk factor related to all-cause mortality of cardiovascular events in patients with chronic kidney disease (CKD). Vascular extracellular matrix (ECM) proteins have been demonstrated to regulate vascular calcification. ECM protein thrombospondin 1 (THBS1/TSP-1) plays a critical role in the regulation of vascular diseases. However, whether THBS1 is involved in vascular calcification in CKD patients remains unclear. In this study, RNA sequencing datasets from the Gene Expression Omnibus (GEO) database GSE146638 showed that THBS1 was upregulated in the aortas of CKD rats. Enzyme-linked immunosorbent assay (elisa) revealed that serum THBS1 levels were increased in CKD patients with thoracic calcification. Western blotting and immunofluorescence analysis showed that THBS1 expression was increased in calcified vascular smooth muscle cells (VSMCs) and arteries. THBS1 knockdown exacerbated rat VSMC calcification induced by high phosphorus and calcium, as shown by Alizarin red staining and calcium content assays. Conversely, THBS1 overexpression attenuated VSMC calcification and abdominal aortic calcification in rats with CKD. Moreover, addition of recombinant THBS1 protein inhibited calcification of VSMC S and human arterial rings. Smooth muscle cell-specific knockout of THBS1 mice treated with vitamin D3 displayed aggravated aortic calcification. Mechanistically, the protein–protein interaction database STRING ( http://string-db.org/ ) analysis and coimmunoprecipitation assays revealed THBS1 bound to integrin β3. Reduction of integrin β3 levels abrogated the protective effect of THBS1 on vascular calcification. RNA-seq analysis revealed that THBS1 overexpression modulated the nuclear factor-kappa B (NF-κB) signaling pathway. Of note, the inhibitory effect of THBS1 overexpression on the NF-κB signal was abolished by knockdown of integrin β3. In conclusion, THBS1 interacts with integrin β3 to inhibit vascular calcification through suppression of NF-κB signal, suggesting a promising therapeutic target for vascular calcification in CKD. © 2025 The Pathological Society of Great Britain and Ireland.
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Tissue Barriers
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2024
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IF 3.6
Qi Cao,Wei Zeng,Jingmin Nie,Yongjun Ye,Yanchao Chen
Impairment of the blood – brain barrier (BBB) and subsequent inflammatory responses contribute to the development of human immunodeficiency virus (HIV)-1-associated neurocognitive disorders (HAND). Apelin-13, the most abundant member of the apelin family, acts as the ligand of the angiotensin receptor-like 1 (APJ). However, its pharmacological function in HAND and its underlying mechanism are unknown. In the current study, we report that the presence of HIV-1 Tat reduced the levels of Apelin-13 and APJ in the cortex tissue of mice. Importantly, Apelin-13 preserved BBB integrity against HIV-1 Tat in mice by increasing the expression of the tight junction protein zonula occludens-1 (ZO-1) and occludin. Interestingly, increased macrophage infiltration, indicated by elevated CD68-positive staining was observed in the cortex after stimulation with HIV-1, which was mitigated by the administration of Apelin-13. Correspondingly, Apelin-13 reduced the expression of monocyte chemoattractant protein-1; (MCP-1). An in vitro two-chamber and two-cell trans-well assay demonstrated that HIV-1 Tat challenge significantly promoted macrophage migration, which was notably attenuated by the introduction of Apelin-13. Accordingly, treatment with Apelin-13 restored the HIV-1 Tat-induced reduction of occludin and ZO-1, while preventing the upregulation of MCP-1 in human brain microvascular endothelial cells (HBMVECs). Our results suggest that Apelin-13 may reduce macrophage infiltration into brain tissues and mitigate BBB dysfunction in patients with HAND.
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PubMed
高影响因子
POLYMER
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2024
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IF 4.1
Xuelin Zhang,Shuangqi Song,Jingde Li,Yanqin Yang
Capturing CO 2 from flue gas of coal-burned power plants has been considered to be a promising technology to mitigate the environmental problems caused by rising level of CO 2 at the atmosphere. Amine-functionalized adsorbents, showing impressive CO 2 adsorption capability and selectivity even at low CO 2 partial pressure, face the challenge of permanent structural changes and performance deterioration due to the irreversibly bonding of SO 2 , a common impurity of flue gas, particularly under humid condition. Besides, the reported amine-functionalized adsorbents are usually nano-sized powders, impractical for industrial applications. Therefore, the development of efficient, stable, and structured CO 2 adsorbents is still an urgent need. Herein, we develop a novel structured mixed-matrix adsorbent (PIM-PP-DETA), using a diethylenediamine-appended porous organic copolymer (PP-DETA, prepared by a copolymerization reaction of dichloro- p -xylene and 4,4′-bis(chloromethyl)biphenyl and a one-step amine grafting process) as main adsorbent and PIM-1 as polymer matrix through a phase inversion process. The as-developed PIM-PP-DETA not only exhibits high CO 2 adsorption capacity and outstanding CO 2 selectivity over N 2 , but also shows fast adsorption kinetics and high stability under repeated adsorption-desorption cycling under dynamic flow conditions. Furthermore, PIM-PP-DETA possesses high tolerance towards acidic and moist environments, with CO 2 adsorption capacity remained at a relatively high level after SO 2 and humid exposure, suggesting its potential usage to post-combustion CO 2 capture.
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Arabian Journal of Chemistry
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2024
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IF 5.3
Ping Cheng,Botao Wang,Shuying Liang,Yuqi Yang,Shixin Gui,Kai Zhang,Yingying Sun,Shaoqi Qu,Lin Li
Colistin used to be regarded as the last-resort treatment for the infection caused by multidrug-resistant gram-negative bacteria. However, the emergence and widespread of mcr-1 seriously reduce the clinical effectiveness of colistin, constituting a serious threat to global public health. Due to the difficulties in the development of new antibiotics, restoring antibiotic susceptibility with adjuvants is undoubtedly a rational option. As naturally occurring compounds, resveratrol and capsaicin could be extracted from many natural plants, due to various antimicrobial properties, they have received significant attention. Herein, the synergistic activity of colistin combined with resveratrol and capsaicin against mcr-1 -positive Escherichia coli were investigated by checkerboard method and time-killing assays. The in-depth molecular mechanisms were elucidated by scanning electron microscopy, fluorescent probe experiments, transcriptome and metabolome analysis. Molecular docking assay was taken to analyse potential interactions between resveratrol/capsaicin and MCR-1. Finally, the in vivo efficacy of combined therapy against mcr-1- positive Escherichia coli was assessed. Our results demonstrated that colistin combined with resveratrol and capsaicin acted synergistic activity against mcr-1- positive Escherichia coli both in vivo and in vitro . Further mechanistic studies showed that the combined therapy could exacerbate cell membrane damage, increase membrane permeability, disrupt the homeostasis of PMF, inhibit ATP synthesis, and efflux pump activity. In addition, the combined therapy could inhibit central carbon metabolism, and reduce tricarboxylic acid cycle and oxidative phosphorylation. Moreover, molecular docking assay revealed resveratrol/capsaicin could bind to MCR-1 stably. Our study indicated that colistin in combination with resveratrol and capsaicin as a novel therapy could provide a trustworthy foundation to establish the treatment plan for mcr-1- positive Escherichia coli.
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