JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2024
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IF 9.4
Jiaqi Li,Yuxi Zhang,Hanhao Liang,Jiaming Li,Xiao Yu,Jianglin Wang,Yini Long,Zhanhong Yang
Manganese oxide is a promising cathode material for rechargeable batteries due to its high theoretical specific capacity. However, its practical application is hindered by its poor conductivity and rapid capacity decay caused by Jahn-Teller distortion during charging and discharging. This work introduces Na 2 EDTA during the synthesis of Mn O 2 , and the amino group is introduced by adsorption to deposit to form N-doped Mn O 2 . Alkaline N-doped Mn O 2 battery upshifts the d-band center of Mn, improves the conductivity of Mn O 2 and the formation energy of O vacancies during the charge-discharge process, and suppresses Jahn Teller distortion. As a result, N-doped Mn O 2 achieves a high capacity of up to 197mAh g −1 and excellent capacity retention of 94.2% over 250 cycles with slower voltage decay. This strategy enables the material with high cycling performance for single-electron discharge secondary alkaline manganese batteries.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2024
·
IF 8.1
Jiachen Zou,Guanying Song,Anguo Cui,Jinfeng Cui,Zhenjiang Li
The rational design of highly active electrocatalysts for water electrolysis remains challenging for green hydrogen utilization . Herein, guided by the correlation between the electroactivity and the d-band center (E d ), a novel hierarchical nanoarchitecture (Ni 2 P/NiFe 2 O 4 -V O @N-GTs) was fabricated, in which, Ni 2 P nanoparticles are grown on the oxygen vacancy-rich NiFe 2 O 4 nanosheet arrays anchoring on N-doping graphene tubes. The results reveal that the multiple strategies including the vacancies and heterogeneous interface construction effectively induce the charge redistribution, and further adjust the E d to the appropriate energy level, which endows the optimal balance between the adsorption and desorption ability of the catalyst to reaction intermediates, thus leading to the conspicuous electrocatalytic activity . Additionally, the hierarchical nanoarchitecture contributes to the exposure of more active sites, the efficiency of electron transfer , and the release of generated gas. Hence, Ni 2 P/NiFe 2 O 4 -V O @N-GTs presents superior bifunctional activity, especially a low overpotential of 194 mV at 10 mA cm −2 for OER . The corresponding overall water electrolyzer owns a lower cell voltage and long-term durability with continuously operating over 330 h at 100 mA cm −2 , outperforming the most reported bifunctional electrocatalysts . This work presents an effective pathway for regulating the E d through multiple strategies to improve the catalytic performance of catalysts.
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POLYMER INTERNATIONAL
·
2017
·Vol. 67
·期 3
·313-321
·
IF 2.07
Chunyan Luo,Minrui Yang,Wei Xiao,Jingjing Yang,Yan Wang,Weixing Chen,Xia Han
Poly( l -lactic acid) (PLLA) is a good biomedical polymer material with wide applications. The addition of poly(ethylene glycol) (PEG) as a plasticizer and the formation of stereocomplex crystals (SCs) have been proved to be effective methods for improving the crystallization of PLLA, which will promote its heat resistance. In this work, the crystallization behavior of PEG and PLLA/poly( d -lactic acid) (PDLA) in PLLA/PDLA/PEG and PEG- b -PLLA/PEG- b -PDLA blends has been investigated using differential scanning calorimetry, polarized optical microscopy and X-ray diffraction. Both SCs and homocrystals (HCs) were observed in blends with asymmetric mass ratio of PLLA/PDLA, while exclusively SCs were observed in blends with approximately equal mass ratio of PLLA/PDLA. The crystallization of PEG was only observed for the symmetric blends of PLLA 39k /PDLA 35k /PEG 2k , PLLA 39k /PDLA 35k /PEG 5k , PLLA 69k /PDLA 96k /PEG 5k and PEG- b -PLLA 31k /PEG- b -PDLA 27k , where the mass ratio of PLLA/PDLA was approximately 1/1. The results demonstrated that the formation of exclusively SCs would facilitate the crystallization of PEG, while the existence of both HCs and SCs could restrict the crystallization of PEG. The crystallization of PEG is related to the crystallinity of PLLA and PDLA, which will be promoted by the formation of SCs. © 2017 Society of Chemical Industry
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JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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2025
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IF 3.1
Xiaolin Wu,Qiao Yu,Yuzhao Hou,Xuemei Zhang,Simon Sani Ocholi,Liming Wang,Ziping Yan,Jie Li,Lifeng Han
Cholestatic liver disease(CLD) is caused by impaired bile flow due to obstruction of the biliary tract, and long-term exposure to bile acids in the liver triggers inflammation, eventually leading to liver toxicity and liver fibrosis. Emodin-8- O-β -D-glucopyranoside(EG) is anthraquinone compound that is widely found in traditional Chinese medicine. It possessed antioxidative and anti-inflammatory activities. However, the effect of EG on cholestatic liver injury(CLI) has not been explored. In this study, Alpha-naphthyl isothiocyanate(ANIT)-induced CLI mice were used to investigate the anti-cholestasis and hepatoprotective effects of EG through serum biochemical index detection, non-targeted metabolomics, lipidomics, and intestinal flora 16S rRNA sequencing. The results suggested that EG restores homeostasis of the gut microbiome while regulating bile acids metabolism and lipid-related metabolic pathways to reduce liver damage in ANIT-induced cholestasis. This study provides a new perspective on the mechanism of EG, and help offer a more natural approach to managing liver damage.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Chenran Xin,Pinhui Jia,Yan Zhao,Zhiqiang Cheng,Wencong Liu,Peng Di,Wei Li,Hongyan Zhu
The healing of wounds in aging skin is a challenging issue that has not been thoroughly studied. Composite hydrogels made from natural polysaccharides have shown potential as dressings for various types of wounds. In this study, we prepared a polysaccharide-based composite hydrogel to provide a new strategy for treating aging skin wounds. First, chitosan (CS) was modified and Gastrodin (GAS) was grafted onto its main chain structure to obtain GAS/CS. Then GAS/CS was mixed with oxidized Gastrodia elata polysaccharides (GEP) to form a hydrogel using the principle of adsorbent reaction, and Puerarin (PUE), a natural plant ingredient, was embedded by gelatin microspheres and then loaded into the hydrogel. As a result, the composite hydrogel effectively reduced oxidative stress in tissue cells at the wound site and inhibited bacterial growth. It also reduced inflammation, promoted angiogenesis, and enhanced collagen deposition, which facilitated the repair of all aspects of the wound healing process in aging mouse skin. In short, this study explored the anti-aging effects of polysaccharides from Gastrodia elata , which might serve as both a treatment and an auxiliary for aging skin wounds. Additionally, the Gastrodia elata polysaccharide hydrogel was expected to be a promising drug carrier for skin repair.
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JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2024
·
IF 5.8
Ji Liu,Hao Fu,Bin Hu,Guan-zheng Zhou,Shou-gang Wei,Zhen-xi Zhang,Qiang Lu
Pyrolysis, a promising thermochemical conversion technique, can convert lignocellulosic biomass into various value-added products. Herein, the selective production of 1,4:3,6-dianhydro-α- d -glucopyranose (DGP) was achieved through fast pyrolysis of cellulose based on oxalic acid-assisted torrefaction (OAT) pretreatment. The mixture of cellulose and oxalic acid first underwent torrefaction, followed by fast pyrolysis to yield DGP. Simultaneously, the air atmosphere was considered to facilitate the formation of esterification intermediates, thereby promoting the formation of DGP. The effects of torrefaction temperature, oxalic acid amount, as well as pyrolysis temperature were carefully explored for DGP production. A yield of 9.6 wt% and a selectivity of 57.5 % for DGP were achieved from the micro-scale pyrolysis of cellulose under the optimized conditions. In lab-scale tests, the DGP yield reached 12.5 wt% from cellulose. The OAT-based pyrolysis was confirmed to be applicable to the waste cellulose-rich materials, with a DGP yield of 8.2 wt% from waste cotton and 6.0 wt% from spent paper in lab-scale experiments. Additionally, the OAT-based pyrolysis also showed the potential for poly-generation of DGP and formic acid at different stages.
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JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2024
·
IF 4.5
Zhenyu Zhao,Ruihuan Ding,Yumei Wang,Ranran Yuan,Houqian Zhang,Tianyang Li,Wei Zheng,Entao Chen,Aiping Wang,Yanan Shi
The glucagon-like peptide-1 (GLP-1) analogue used to treat diabetes is an increasingly popular polypeptide protein therapeutic, commonly marketed as an injection. However, the effective oral administration of peptide drugs remains challenging because of their extremely low bioavailability. In recent years, a number of delivery systems that have been shown to be effective in improving the therapeutic efficacy of oral drugs. Herein, liraglutide was employed as a model drug and amphoteric sulfobetaine (SB12) was selected for the surface modification of poly (D, L-lactide-co-glycolic acid) (PLGA) nanoparticles (NPs) to obtain hydrophilic and electroneutral SB12-NPs. The functional SB12-NPs were first screened to identify the optimal prescription process and obtained from the final prescription were evaluated. The particle size, zeta potential , encapsulation efficiency (EE%) and drug-loading (DL%) of SB12-NPs were 87.25 ± 0.77 nm, −3.91 ± 1.88 mV, 77.45% ± 1.62%, and 10.46% ± 0.21%, respectively. The cellular uptake of Lira-SB12 NPs was significantly better than that of free liraglutide, and verified that it was transported mainly through endocytosis mediated by clathrin- and lipid raft–mediated. The trans-mucous permeability (2.86-fold) and intestinal permeability (1.79-fold) of SB12-NPs were significantly higher than those of free liraglutide. Single and multiple doses of SB12-NPs showed that the blood sugar level of diabetic mice could be lower to about 70% of the initial value. The SB12-NPs demonstrated a higher relative bioavailability of 9.59% compared with that of oral pure liraglutide (5.13%). Thus, SB12-modified PLGA NPs with hydrophilic and electroneutral surface properties can significantly improve mucus permeability and oral bioavailability, and have the potential to be applied for oral delivery of peptides and proteins .
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Nano Today
·
2025
·
IF 10.9
Yong Jiang,Zhong Liang,Hao Fu,Guangtong Hai,Yaping Du
Rare earth oxides (REOs) hold a pivotal position in enhancing electrocatalytic performance, yet the comprehension of their underlying mechanisms poses significant challenges. In this study, REOs loaded with a ternary alloy, abundant in oxygen vacancies, were synthesized through a one-pot reduction method and exhibited remarkable oxygen evolution reaction (OER) activity. The interaction at the interface between Fe 0.3 NiCo and CeO 2 induced substantial lattice distortion and modulated the oxygen vacancy concentration within the REOs. A unique electron transport channel, incorporating transition metal (3d) -oxygen vacancy (Vo) -rare earth (4 f) elements, was constructed at the interface, significantly boosting the OER activity of NiCo-CeO 2 . Notably, a current density of 10 mA cm −2 was achieved at a low overpotential of 151 mV. Comprehensive characterizations revealed that the interplay between the alloy and REOs regulated the oxygen vacancy concentration of the latter. In-situ attenuated total reflection infrared spectroscopy (ATR-IR) further confirmed that REOs facilitated the adsorption of O 2 /-OH, thereby enhancing OER activity. Theoretical calculations also indicated that oxygen vacancies effectively shifted the d and f band centers near the Fermi level, promoting d-f electron exchange and ensuring efficient electron transfer. This study offers a novel perspective for the development of efficient RE-based catalysts.
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Journal of the American Chemical Society
·
2025
·
IF 15.6
Mingyan Chuai,Hao Tong,Zimin Yang,Siting Deng,Mingqiang Wu,Jidan Xing,Guoliang Chai
An electrolytic Zn–MnO2 battery is highly valued due to its cost-effectiveness, environmental friendliness, and abundant resource availability. However, the battery’s performance is hindered by the slow kinetics at the poorly conductive MnO2 cathode and hydrogen evolution at the Zn anode. Here, a strategy of P–O–M (M = Mn, Zn) d-pπ backbonding design is proposed for phosphorus–oxygen electrolyte additives, which can be realized by tuning the atomic dipole moment-corrected Hirshfeld (ADCH) population charge of the P/O atom. The reversibility of d-pπ backbonding not only leads to the fast kinetics of Mn2+/Zn2+ at electrodes during both charge and discharge processes to suppress the competitive hydrogen evolution reaction but also enhances the electronic conductivity at the electrode–electrolyte interfaces to sustain the high areal capacity of batteries. Hydroxymethyl dimethyl phosphite (HPD) with d-pπ backbonding is a preferred additive with a suitable ADCH charge. The assembled electrolytic Zn–MnO2 (HPD) battery exhibits a high discharge capacity of 14.05 mAh cm–2 at an areal capacity of 15 mAh cm–2 and superior cycling stability over 1500 cycles. The Zn–MnO2 (HPD) soft-pack battery exhibits a discharge capacity of over 1.60 Ah at a discharge rate of 0.5 C and maintains a Coulombic efficiency of ∼80% over 100 cycles. Furthermore, the assembled 50 V 40 Ah commercial Zn–MnO2 (HPD) battery can drive an electric vehicle for 10 km. The ADCH charge regulation provides a feasible and effective method for developing high-performance aqueous batteries by achieving d-pπ backbonding.
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ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Zizai Ma,Zihao Wan,Shuaili Zhao,Jinping Li,Jianping Du,Xiaoguang Wang
Bimetallic single-atom catalysts have garnered considerable interest in the field of the oxygen reduction reaction due to their unique electronic configurations and synergistic catalytic effects. However, precise modulation of d-orbital electron distribution at single-atom sites and comprehensive elucidation of the underlying catalytic mechanisms continue to present significant challenges. Herein, the FeCo(mlm)–N–C catalyst, integrating atomically dispersed Fe–Co dual-metal sites and Fe3C nanoparticles, was synthesized by using an encapsulation and ligand exchange strategy. Comprehensive analyses and theoretical simulations reveal that the incorporation of Fe3C nanoparticles induces significant d-orbital electron delocalization at the Fe active sites. This tailored electronic configuration effectively modulates Fe d–O p hybridization between the Fe active sites and adsorbed OH*. Consequently, it optimizes the occupancies of bonding and antibonding orbitals, thereby accelerating OH* desorption. This mechanism enables FeCo(mlm)–N–C to exhibit excellent catalytic performance and remarkable stability in both acidic and alkaline environments, while demonstrating superior activity in zinc-air batteries and proton exchange membrane fuel cells. This work not only presents a highly efficient non-noble metal electrocatalyst but also provides valuable insights into the rational development of advanced transition metal–nitrogen–carbon catalysts for energy-related applications.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2025
·
IF 21.1
Xiangling Wang,Zhimin Li,Zhengfu Zhang,Chengping Li,Rui Bao,Zhishan Li,Jinsong Wang
Elevating the lattice oxygen p -band center (ε p ) is critical to trigger the lattice oxygen mechanism (LOM) for boosting oxygen evolution reaction (OER) activity in advanced electrocatalysts, but it also causes a reduced d -band center (ε d ) due to the coupled metal-oxygen d - p orbital, resulting in a sluggish regeneration of lattice oxygen. Herein, we surmount this challenge by heterojunction and defect-engineering to raise both ε d and ε p of CeO 2 NPs/D-Ni(OH) 2 . The formative built-in electric field and defect reduce the electronic density of Ni(OH) 2 , effectually decreasing the deprotonation energy and promoting its surface reconstruction into γ-NiOOH, the formative high valence Ni δ+ raises ε p to trigger LOM. Meanwhile, the ε d is upshifted by the high f -band of CeO 2 , accelerating the adsorption of oxygenous species to replenish the lattice oxygen vacancies. Consequently, the CeO 2 NPs/D-Ni(OH) 2 demonstrates exceptional OER activity, requiring only 169 mV to reach 10 mA cm −2 , and maintains impressive stability over 300 h at 1000 mA cm −2 in 1 M KOH. This work presents a novel strategy to balance lattice oxygen participation and regeneration by rising d - p orbital for inducing and maintaining LOM activity.
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Foods
·
2025
·Vol. 14
·期 15
·2645
·
IF 5.1
Cong Zhang,Kai Jiang,Yilin Lin,Rui Cui,Hong Wu
In this study, a composite film with dual antioxidant and antibacterial properties was prepared by combining 2% chitosan and 7% gelatin (2:1, w:w), with D-carvone (0–4%) as the primary active component. The effect of D-carvone content on the performance of the composite films was systematically investigated. The results showed that adding 1% D-carvone increased the water contact angle by 28%, increased the elongation at break by 35%, and decreased the WVTR by 18%. FTIR and SEM confirmed that ≤2% D-carvone uniformly bonded with the substrate through hydrogen bonds, and the film was dense and non-porous. In addition, the DPPH scavenging rate of the 1–2% D-carvone composite film increased to about 30–40%, and the ABTS+scavenging rate increased to about 35–40%; the antibacterial effect on Escherichia coli and Staphylococcus aureus increased by more than 70%. However, when the addition amount was too high (exceeding 2%), the composite film became agglomerated, microporous, and phase-separated, affecting the film performance, and due to its own taste, it reduced the sensory quality of the noodles. Comprehensively, the composites showed better performance when the content of D-carvone was 1–2% and also the best effect for freshness preservation in Xinjiang ramen. This study provides a broad application prospect for natural terpene compound-based composite films in the field of high-moisture, multi-fat food preservation, and provides a theoretical basis and practical guidance for the development of efficient and safe food packaging materials. In the future, the composite film can be further optimized, and the effect of flavor can be further explored to meet the needs of different food preservation methods.
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