MICROCHIMICA ACTA
·
2019
·Vol. 187
·期 1
·1-9
·
IF 5.479
Jin Yafeng,Li Xiaobo,Ge Chuangye,Ma Jingjing,Li Yuanchao,Zhao Erqing,Yao Shuwen,Xu Guangri,Li Donghao
A comparative study was carried out on the electrochemical behavior of three carbonized zeolitic imidazolate frameworks (ZIFs) synthesized through solvothermal pyrolysis. An electrochemical sensor for acetaminophen (ACT) was subsequently developed. The sensor was made by coating the glassy carbon electrode (GCE) with cobalt-nitrogen co-doped carbon nanotube hollow polyhedron (Co-NCNHP), which was prepared from core shell ZIF-8@ZIF-67, before electrodeposition of gold nanoparticles. Due to the high specific surface area, good electrical conductivity and stability of both Co-NCNHP and the gold nanoparticles, the resultant sensor displayed excellent electrocatalytic activity towards ACT with the catalytic rate constant K cat of 4.9 × 10 5 M −1 s −1 , diffusion coefficient D of 1.8 × 10 −6 cm 2 s −1 , high sensitivity of 1.75 μA μM −1 cm −2 , and best at a working voltage of 0.35 V (vs. Ag/AgCl). Benefitting from the synergistic effect of both Co-NCNHP and gold nanoparticles, the modified GCE had a linear response in the 0.1 μM–250 μM ACT and detection limit of 0.05 μM (at S/ N = 3). The sensor was successfully applied to quantify ACT in tablets and spiked urine samples with recoveries ranged between 96.0% and 105.2%.
Schematic representation of cobalt-nitrogen co-doped carbon nanotube hollow polyhedrons (Co-NCNHP) exhibiting superior electrocatalytic activity to carbonized ZIF-8 and carbonized ZIF-67. Co-NCNHP were coupled to electrodeposition gold nanoparticles to modify glassy carbon electrode for improving acetaminophen (ACT) redox.
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高影响因子
MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 5
·1-8
·
IF 5.705
Wang Zonghua,Yu Gege,Xia Jianfei,Zhang Feifei,Liu Qingyun
The authors demonstrate the exploitation of reduced graphene oxide (RGO) as a template for immobilizing zeolitic imidazolate framework-8 (ZIF-8) crystals loaded with the electrochemical probe Methylene Blue (MB). The framework was deposited on the surface of RGO in a one-pot process. Transmission electron microscopy, scanning electron microscopy and X-ray diffraction were employed to characterize the nanocomposite. The electrochemical behavior of rutin at a glassy carbon electrode (GCE) modified with the nanocomposite was investigated by cyclic voltammetry and differential pulse voltammetry. The modified GCE displays high electrocatalytic activity toward rutin oxidation at a relatively low working potential (0.4 V vs. Ag/AgCl). Under the optimal conditions, the sensor has an amperometric response that is linear in the 0.1 to 100 μM rutin concentration range, with a 20 nM detection limit (at an S/N ratio of 3). The method was successfully applied to the determination of rutin in tablets and urine samples.
The zeolitic imidazolate framework ZIF-8 was loaded with Methylene Blue and deposited on the surface of reduced graphene oxide. A glassy carbon electrode was modified with the nanocomposite and then used for the determination of rutin with a 20 nM detection limit and a linear range from 0.1 to 100 μM.
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2021
·Vol. 45
·期 35
·15876-15886
·
IF 3.591
Xiao Zhang,Zhiyue Li,Taoyi Zhang,Jing Chen,Wenxi Ji,Yun Wei
A novel zeolitic imidazolate framework-8 (ZIF-8) alginate composite hydrogel material (PVA/SA@ZIF-8) is an alginate composite bead which was fabricated by grafting ZIF-8 on the surface of the sodium alginate hydrogel beads using an in situ growth method. The synthetic material was characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, high resolution transmission electron microscopy, X-ray photoelectron spectroscopy, and thermogravimetric analysis. The PVA/SA@ZIF-8 bead was used to effectively adsorb Cu(II) from aqueous solutions. The initial concentration of copper ions, adsorbent dose, initial pH of copper ions solution, temperature, and contact time for the synthesis of the material were optimized. The adsorption isotherms and kinetics fitted to the Langmuir isotherm model (R2 = 0.9992) and the pseudo-second-order kinetic model (R2 = 0.9967) respectively. According to the Langmuir isotherm adsorption model, the maximum theoretical adsorption capacity of the adsorbent for Cu(II) was 166.94 mg g−1. In addition, the recycling application of the adsorbent was possible as it was easily collected and reused after five adsorption-regeneration cycles. The results indicated the PVA/SA@ZIF-8 hydrogel has unlimited potential in the treatment of heavy metal wastewater. Moreover, the combination of sodium alginate hydrogel and metal–organic frameworks would broaden the potential application of hydrogel materials in other fields.
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ACS Sensors
·
2025
·
IF 9.1
Zhenguo Zhang,Xue Li,Shuo Zhang,Mingshuang Zheng,Fangping Yuan,Shushen Li,Bei Yuan,Lisheng Liu,Xin Du
Although immunotherapy has become an established approach in cancer treatment, not all patients exhibit a positive response. Current research on PD-1 primarily focuses on immune cells using conventional methods, yet PD-1 expression on tumor cells is also widespread and plays an increasingly critical role in assessing immunotherapy efficacy. To address this, we developed an electrochemical biosensor capable of specifically detecting PD-1 at both the protein and tumor cellular levels in situ, eliminating the need for sample fixation and thereby streamlining the analytical process. Additionally, our probe enables simultaneous localization analysis of PD-1 through fluorescence signaling. The biosensor integrates a bifunctional probe composed of a nanometal–organic framework (MOF, ZIF-8) conjugated with quantum dots (QDs) and an electrode modified with a carbon nanotube (CNT)–gold nanoparticle (AuNP) nanocomposite. The morphology and performance of the nanocomposite were thoroughly characterized, and the resulting PD-1 biosensor demonstrates high specificity, reproducibility, and sensitivity. To facilitate clinical translation, we successfully applied the biosensor to detect differential PD-1 expression across various tumor cell lines and cancer tissues. This study establishes that our dual-mode electrochemical and fluorescent sensing platform provides a powerful tool for in situ PD-1 detection on tumor cells, offering valuable insights for evaluating tumor immunotherapy responses.
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高影响因子
CARBON
·
2025
·
IF 11.6
Zhongkai Zhao,Xiaobo Zhu,Jiaxi Li,Wenjing Wang,Xiaocheng Jiang,Shan Shi,Siming Ren
Intrinsic self-healing coatings have attracted considerable research interest due to their remarkable ability to repair damage autonomously. However, their insufficient impermeability limits their long-term application in metal corrosion protection. Herein, we embedded corrosion-inhibiting cerium-doped ZIF-8 nanoparticles (Ce@ZIF-8) modified graphene oxide (GO) two-dimensional sheets into an epoxy network containing dynamic hydrogen bonds and disulfide bonds, developing a room-temperature self-healing epoxy/GO-Ce@ZIF-8 composite with remarkable barrier and corrosion resistance properties. Due to the metal coordination interaction between zinc or cerium in GO-Ce@ZIF-8 and the epoxy dynamic network, the modified nanosheets are efficiently and stably dispersed in the epoxy resin. The elaborately designed composite exhibits excellent stretchability (424.95 %), exceptional room-temperature self-healing capabilities (80.7 % at 25 °C for 8 h), and outstanding corrosion resistance. This is ascribed to the synergy of the superior physical shielding effect of nanosheets and the passivation of cerium elements released from nanoparticles on metal surfaces, achieving active/passive long-term corrosion protection through the intrinsic self-healing and external passivation of composite. This innovative strategy provides a new approach to developing novel high-barrier self-healing materials.
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高影响因子
ChemistrySelect
·
2025
·Vol. 10
·期 43
·e04072
·
IF 2
Xiao Bai,Yinxue Zhou,Chunyan Lv,Fanjun Zhang,Ziyin Yang,Zhe Liu
This work demonstrates that Zn single atoms exhibit intrinsic oxidase-like activity. Zn single-atom nanozymes (Zn-SAs/NC) were synthesized via direct pyrolysis of ZIF-8 at 1000 °C under N 2 atmosphere, which retains a rhombic dodecahedral morphology with atomically dispersed Zn sites. Crucially, Zn-SAs/NC exhibited pronounced oxidase-like activity, efficiently catalyzing the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) to blue oxTMB without exogenous H 2 O 2 . Control experiments with metal-free NC confirmed that the catalytic activity originated specifically from the Zn single atoms, challenging the traditional view of Zn's catalytic inertness. The Zn-SAs/NC-catalyzed TMB oxidation system was exploited for colorimetric detection of tannic acid (TA) based on TA's inhibitory effect, achieving high sensitivity (LOD = 0.016 µM) and selectivity. Successful application in real tea samples validated the method's practicality, establishing Zn single atoms as a novel nanozyme platform. Graphical This work develops a Zn single-atom nanozyme (Zn-SAs/NC) derived from ZIF-8 pyrolysis, which exhibits robust intrinsic oxidase-like activity for highly sensitive and selective colorimetric detection of tannic acid with a low detection limit of 0.016 µM.
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JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Tao Jian,Yongjin Fang,Xiang Cai,Mingyi Ying,Bisheng Li,Wangyang Ye,Liguo Shen,Leihong Zhao,Hongjun Lin
The development of high-performance membranes for heavy metal remediation remains a key challenge in advanced water treatment. In this work, a hierarchically structured composite membrane was fabricated via a self-confined growth strategy, in which Zn(OH) 2 nanostrands immobilized MoS 2 and directed the in-situ growth of ZIF-8, forming a defect-free interlayer for robust polyamide (PA) deposition. The resulting ZM15-PA membrane exhibits a highly hydrophilic surface with a contact angle of 31.5°, a strong positive surface charge under acidic conditions, and excellent water permeability reaching 83.5 L m -2 h -1 . Most notably, the membrane achieves an ultrahigh Pb(II) rejection rate of 99.2%, consistently reducing effluent concentrations to less than 10 μg L -1 , even in the presence of coexisting ions and dissolved organic matter. Mechanistic investigations reveal that Pb(II) removal is governed by synergistic mechanisms including electrostatic repulsion, molecular sieving, and coordination interactions involving Pb-S, Pb-O, and Pb-N bonds. Furthermore, the membrane demonstrates outstanding antifouling resistance, long-term operational stability, and antibacterial efficiency exceeding 99% under photo-Fenton conditions. These findings highlight the promise of self-confined growth strategies for stabilizing two-dimensional materials and developing multifunctional membranes for selective heavy metal removal in complex water matrices.
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Regenerative Biomaterials
·
2025
·
IF 8.1
Zhang Ting,Yu Yameng,Yuan Wei,Ren Zeqi,Cheng Yan,Wu Shuilin,Zheng Yufeng,Xia Dandan
Biodegradable Zn alloy have recently gained considerable attention for use in bone implants considering their biodegradability, attractive mechanical properties, and bioactivity. However, excessive corrosion of Zn alloy at the early stage of implantation may cause severe cytotoxicity, resulting in insufficient osseointegration, which hinders the clinical use of the Zn alloy. In this study, we designed a photothermal-controlled degradative hybrid coating as corrosion-protective barrier with the intention of preventing Zn ion burst release during the early stages of implantation and regaining the alloy's corrosion advantage later on. The coating consisting of Zeolite imidazole skeleton-encapsulated indocyanine green core-shell structured nanoparticles and polylactic coglycolic acid (ICG@ZIF-8/PLGA) on pristine Zn-0.8 (wt.%) Li (ZL) alloy. The electrochemical test results indicated that coating ZL with ICG@ZIF-8/PLGA might effectively reduce its corrosion current density (icorr) from 2.48 × 1 0 −5 A•cm−2 to 2.10 × 1 0 −8 A•cm−2. After near-infrared light irradiation, ICG@ZIF-8 heated PLGA coating to reach Tg, so that the coating was degrading, and the icorr of coated ZL alloy decreased to 2.50 × 1 0 −7 A•cm−2, thus restoring corrosion advantage. Both in vitro and in vivo investigations showed that coated ZL alloy had acceptable biocompatibility. Overall, the development of the photothermally controlled coating improved the Zn alloy's resistance to corrosion and allowed for the adjustment of the coated ZL alloy's rate of degradation through the use of 808 nm NIR laser irradiation.
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高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Junhao Liu,Jinshi Yu,Xiaoyan Wang,Meng Cheng,Shuangqing Sun,Songqing Hu,Chunling Li,Zhikun Wang
Metal–nitrogen–carbon (M–N–C) catalysts obtained from zeolitic imidazolate frameworks (ZIFs) have great potential in the oxygen reduction reaction (ORR). Herein, based on the same three-dimensional (3D) topological structure of ZIF-67 and ZIF-8, ZIF-67 is grown on the ZIF-8 surface by the epitaxial growth method, and ZIF-8 is used as a sacrificial template to obtain a Co-embedded layered porous carbon nanocage (CoPCN) electrocatalyst. Meanwhile, the self-sacrificing template effectively improves the specific surface area of the porous structure and reduces the depletion of active sites. The CoPCN shows a high half-wave potential of 0.885 V and superior stability as well as excellent methanol resistance. Theoretical calculations demonstrate that the Co–N1–C2 sites of CoPCN effectively reduce the energy barrier of ORR. In addition, a zinc–air battery (ZAB) based on the CoPCN exhibits excellent peak power density (90 mW cm–2) and superior cycle performance. This work presents a novel idea in the design of ZIF precursor systems to synthesize efficient ORR catalysts.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2016
·
IF 3.014
Jianxin Liu,Rui Li,Yunfang Wang,Yawen Wang,Xiaochao Zhang,Caimei Fan
For detecting the active roles of ZIF-8 in composite photocatalyst , a novel Ag/AgCl/ZIF-8(50%) composite photocatalyst was designately prepared by anchoring Ag/AgCl nanoparticles on the surface of ZIF-8 with 50% content. The adsorption and photocatalytic performance of Ag/AgCl/ZIF-8(50%) were conducted by removal of Rhodamine B (RhB) from aqueous solution under dark and visible light irradiation (λ > 420 nm). The experimental results showed that the as-synthesized Ag/AgCl/ZIF-8(50%) exhibited higher photocatalytic activity than Ag/AgCl. The XRD , TEM , FTIR, DRS, VB XPS, ESR, N 2 adsorption isotherms and active species trapping experiments were used to characterize the performance of the composite photocatalyst. We found that the ZIF-8 in composite photocatalyst not only has the adsorption ability for RhB by its large specific area, but also has the ability for the formation of O 2 · − by an appropriate position of conduction band (CB). A reasonable reaction mechanism with a new perspective on the composite photocatalyst of Ag/AgCl/ZIF-8(50%) was proposed. This insight on the active roles of ZIF-8 in Ag/AgCl/ZIF-8(50%) may open a window for the use of MOF material in photocatalytic field.
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Jiali Tang,Viatcheslav Freger,Lu Shao,Xuezhong He
Metal-organic frameworks (MOFs)-based hybrid composite membranes are promising candidates for achieving highly efficient water purification. In this study, a facile, novel pressure-induced filtration method involving in-situ polymerization of butyl methacrylate (BMA) was proposed for sealing ZIF-8 nanoparticles on top of polyethersulfone (PES) ultrafiltration membrane support. The developed (ZIF-8+polyBMA)/PES composite membranes with thin toplayers of <1 μm present attractive water permeance (up to 31 LMH/bar) and good rejection of Congo red (99.2 %) and Methylene blue (99.1 %). The ZIF-8 particles served as direct-through channels with superior separation performance due to their high porosity and tunable pore structure, while the interstices were successfully sealed with polyBMA by in-situ polymerization, as demonstrated by SEM and dye removal experiments. It was found that the morphology of ZIF-8 transformed from a rhombic dodecahedron to two-dimensional hexagonal nanosheets during the fabrication process. We hypothesize that this surprising phenomenon is caused by the reaction of the initiators (Na 2 S 2 O 5 and K 2 S 2 O 8 ) that generate the hydroxyl and sulfate radicals attacking and transforming the Zn-MIM bond network of ZIF-8. However, insights into the structural changes need to be further investigated to understand the mechanism involved.
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高影响因子
Exploration
·
2024
·
IF 0
Xiaoxue Li,Wei Wang,Qiuxia Gao,Shanshan Lai,Yan Liu,Sitong Zhou,Yan Yan,Jie Zhang,Huanhuan Wang,Jiamei Wang,Yi Feng,Ronghua Yang,Jianyu Su,Bin Li,Yuhui Liao
Infected burn wounds are characterized by persistent drug-resistant bacterial infection coupled with an inflammatory response, impeding the wound-healing process. In this study, an intelligent nanoparticle system (CCM+TTD@ZIF-8 NPs) was prepared using curcumin (CCM), an aggregation-induced emission luminogens (TTD), and ZIF-8 for infection-induced wound healing. The CCM+TTD@ZIF-8 NPs showed multiple functions, including bacteria targeting, fluorescence imaging and pH response-guided photodynamic therapy (PDT), and anti-inflammatory. The positive charges of ZIF-8 NPs allowed the targeting of drug-resistant bacteria in infected wounds, thereby realizing fluorescence imaging of bacteria by emitting red fluorescence at the infected site upon blue light irradiation. The pH-responsive characteristics of the CCM+TTD@ZIF-8 NPs also enabled controllable CCM release onto the infected wound site, thereby promoting the specific accumulation of ROS at the infected site, with outstanding bactericidal efficacy against drug-resistant Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa) strains in vitro/in vivo. Additionally, due to the excellent bactericidal effect and anti-inflammatory properties of CCM+TTD@ZIF-8 NPs combined with blue light irradiation, the regeneration of epidermal tissue, angiogenesis, and collagen deposition was achieved, accelerating the healing process of infected burn wounds. Therefore, this CCM+TTD@ZIF-8 NPs with multifunctional properties provides great potential for infected burn wound healing.
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