ACS Applied Polymer Materials
·
2022
·
IF 4.855
Yun Huang,Weida Zeng,Peirong Li,Qiang Liao,Ao Xia,Xianqing Zhu,Xun Zhu
Microalgal biofilm is one of the most promising candidates for renewable feedstock accumulation and carbon neutralization. To synergistically enhance cell adhesion during the microalgal biofilm formation stage and detachment during the harvesting stage, a surface possessing controllable properties is expected. However, the enhancement of the adhesion capacity of a conventional N-isopropylacrylamide (NIPAM) coating to microalgal cells only happens when the temperature reaches its lower critical solution temperature (LCST) of 33 °C, but at the optimum growth temperature of microalgae (25 °C) its adhesion capacity is dramatically weakened. In this study, a nondependent and environment-friendly thermoresponsive coating with a flexible LCST (22.3–25.0 °C) was prepared by cross-linking poly(NIPAM-co-N-tert-butylacrylamide) onto polydopamine to accelerate the adhesion of microalgal cells onto the coating at the optimum growth temperature of microalgae (25 °C). The coatings exhibited outstanding temperature-switchable performance due to competition between hydrophobic groups and hydrophilic groups in polymer molecules. Based on the temperature-switchable characteristic, the adhesion density of Chlorella sorokiniana MB-1 (C. sorokiniana) on the coating was increased by 49.4% compared to the conventional coating at 25 °C. Meanwhile, at 15 °C, the detachment efficiency of these cells on the coating reached 96.5%. The energy barrier between the C. sorokiniana and the coating was reduced by 54.8% compared to that of these cells on conventional coating, resulting in excellent cell adhesion and release. This report not only designs smart polymers for adjusting the adhesion of microalgal cells but also provides a sustainable strategy for microalgal biofilm cultivation.
研究领域:
生物材料学
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环境科学
·
高分子化学
✓ 已验证
DOI
高影响因子
Chemical Engineering and Processing-Process Intensification
·
2024
·
IF 3.8
Zifei Yan,Grace Dai Zhen Lee,Jian Deng,Guangsheng Luo
The synthesis of terminal epoxides, which are vital components in pharmaceuticals and resins, often involves dehydrochlorination of β-chlorohydrins. Although intrinsic kinetics indicate that the dehydrochlorination reaction in the presence of sodium hydroxide could be very rapid, the practical implementation could always be hindered by long reaction time and low conversion rate. Extended contact between the product and the alkaline solution can lead to hydrolysis of the epoxy group, thus necessitating the process intensification to realize higher production efficiency and selectivity. Here, by characterizing thermodynamic equilibrium data and in-situ recording of the reaction that proceeded in a constant interphase reactor, the heterogeneous dehydrochlorination is demonstrated to occur primarily in the organic phase, and the overall reaction rate depends on the equilibrium concentration of sodium alkoxides. This finding, which is fundamentally different from the traditional view that chlorohydrin is first dissolved in the aqueous phase and then reacts with NaOH, leads us to use inert alcohols to assist in the extraction of NaOH. Based on this method, the reaction time can be reduced over 80 % both in batch and continuous reactors. Besides, the method is demonstrated to be effective in the dehydrochlorination of five different long-chain β-chlorohydrins.
研究领域:
化学工程
·
有机合成
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Yinling Wang,Juan Wang,Dandan Wei,Maoguo Li
M–N–C electrocatalysts for the oxygen reduction reaction (ORR) have been considered as the most promising alternatives to precious metal catalysts. However, the catalytic activity of M–N–C especially in an acidic medium is still unable to meet the practical requirement, and the corresponding ORR mechanism also remains unclear. Herein, an “MOF-protective-pyrolysis” strategy was adopted to synthesize an Fe–N–C catalyst (P-FeMOF@ZIF-8) with Fe–N4 as the predominant Fe species. The P-FeMOF@ZIF-8 displays high catalytic activity in both acidic and alkaline mediums. The experimental results further reveal the different importance of the Fe species in different mediums. Based on the results, a distinct mechanism of the ORR the in acidic medium was proposed, where the synergistic effect of the Fe–N4 site and carbon in improving the kinetics of the ORR were well explained. The findings and the corresponding perspective may provide a new guidance for the design of highly efficient ORR electrocatalysts.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Jing Kang,Jinsong Han,Yangyang Gao,Tianyi Gao,Shi Lan,Linghan Xiao,Yanling Zhang,Ge Gao,Harnoode Chokto,Alideertu Dong
Preventing bacterial infections is a main focus of medical care. Antibacterial agents with broad and excellent disinfection capability against pathogenic bacteria are in fact urgently required. Herein, a novel strategy for the development of N-halamine polymers from spheres to fibers using a combined copolymerization-electrospinning-chlorination technique was reported, allowing fight against bacterial pathogen. Optimizing the process conditions, e.g., comonomer molar ratio, concentration of electrospinning solution, chlorination order, and chlorination period, resulted in the formation of N-halamine fibers with controllable morphology. N-Halamine polymers were tested against two common bacterial pathogens, Escherichia coli and Staphylococcus aureus, and were found to be extremely potent against both bacteria, suggesting that they possess powerful sterilizing properties. Remarkably, compared with those with sphere morphology, N-halamine fibers show unexpected enhancement toward both pathogens possibly because of their shape (fiber morphology), surface state (rough surfaces), and surface charge (positive zeta potentials). It is believed that this approach has great potential to be utilized in various fields where antifouling and antibacterial properties are highly required.
研究领域:
材料科学
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微生物学
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医学工程
✓ 已验证
DOI
高影响因子
REGULATORY TOXICOLOGY AND PHARMACOLOGY
·
2015
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IF 2.031
Xin Wu,Dan Wan,Chunyan Xie,Tiejun Li,Ruilin Huang,Xugang Shu,Zheng Ruan,Zeyuan Deng,Yulong Yin
N -carbamylglutamate (NCG) is a metabolically stable analog of N -acetylglutamate that activates carbamyl phosphate synthase-1, a key arginine synthesis enzyme in enterocytes. It is a promising feed additive in swine in China. In this study, we assessed the acute and sub-acute toxicity of NCG in Sprague–Dawley (SD) rats. All rats survived until they were killed at a scheduled time point. No adverse effects or mortality was observed following acute oral administration of 5000 mg/kg NCG to SD rats. No biologically significant or test substance-related differences were observed in body weights, feed consumption, clinical signs, a functional observational battery, organ weights, histopathology , ophthalmology, hematology, coagulation, and clinical chemistry parameters in any of the treatment groups in sub-acute doses of NCG at target concentrations corresponding to 500, 2000, and 3000 mg/kg/day for 28 days neither. In addition, no evidence of mutagenicity or genotoxicity was found, either in vitro in bacterial reverse mutation assay or in vivo in mice bone marrow micronucleus assay and sperm shape abnormality assay. On the basis of our findings, we conclude that NCG is a non-toxic substance with no genotoxicity.
研究领域:
毒理学
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动物营养学
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分子生物学
✓ 已验证
DOI
高影响因子
Reaction Chemistry & Engineering
·
2020
·Vol. 5
·期 5
·886-895
·
IF 3.441
Xing-Gang Si,Yun-Peng Zhao,Qing-Lu Song,Jing-Pei Cao,Rui-Yu Wang,Xian-Yong Wei
A highly efficient Ni/N–C catalyst was synthesized by facile pyrolysis of a Ni-containing metal–organic framework (Ni-MOF), and its catalytic hydrogenolysis performance towards C–O bonds in lignin was evaluated in detail using diphenyl ether (DPE) as a model compound. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) analyses show that the flower-like nanosheets of the Ni-MOF shrink, forming a loose and ordered spherical structure during pyrolysis. Under the optimal conditions, DPE was completely converted and the selectivity to monomers (benzene, cyclohexanol and cyclohexane) reached 99.1%. During the catalytic hydrogenolysis conversion (CHC) of DPE, the direct cleavage of the Caromatic–O bond affording benzene and phenol is the major reaction pathway, and a low H2 pressure is crucial to increase the monomer selectivity. Furthermore, Ni/N–C-450 shows high hydrogenolysis activity for other lignin-derived aryl ethers, such as benzyl phenyl ether, dibenzyl ether, dinaphthalene ether, benzyl 2-naphthyl ether and 3-methoxyphenol.
研究领域:
化学工程
·
催化材料科学
✓ 已验证
DOI
高影响因子
CATALYSIS COMMUNICATIONS
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2013
·
IF 2.915
Y.-W. Sun,X.-H. Lu,X.-L. Wei,D. Zhou,Q.-H. Xia
Co 2+ -exchanged zeolite catalysts were prepared by an ion-exchange route and firstly applied in the N -alkylation of aromatic amines with alcohols to imines. For the N -alkylation of aniline with benzyl alcohol, the aniline conversion of 89.8 mol% with an imine selectivity of 100% was achieved over Co-13X at 433 K under optimal conditions. The results showed that many factors including the Co loading, the support, the temperature, the alkali, could influence the reactions. Investigations carried out by XRD, SEM and recycling studies indicated that the Co-13X catalyst still remained porous structures of 13X zeolite and possessed a stable catalytic activity.
研究领域:
催化化学
·
材料科学
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Chaoge Zhou,Fanqi Meng,Ke Chen,Xueli Yang,Tianshuang Wang,Peng Sun,Fangmeng Liu,Xu Yan,Kengo Shimanoe,Geyu Lu
In this work, we successfully prepare the octahedral NiO/Zn 2 SnO 4 p-n heterostructure by a simple hydrothermal synthesis and subsequent wet impregnation process. The microscopic morphology characterization results show that the as-prepared composites are uniformly dispersed and have an octahedral structure with a size of 3−5 μm. The gas devices are fabricated and their sensing performances are investigated systematically. The response and selectivity of NiO/Zn 2 SnO 4 composites to acetone have been significantly improved than that of pure Zn 2 SnO 4 . Moreover, the response of the sensor to 100 ppb acetone is 1.4 at 300 °C, indicating that the detection limit is less than 100 ppb. The enhancement in sensing properties of composites is largely due to the p-n heterojunction formed by NiO and Zn 2 SnO 4 , which causes the transfer of carriers and the catalytic effect of NiO.
研究领域:
材料科学
·
传感器技术
✓ 已验证
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2020
·
IF 4.192
Yu Lu,Wanjun Jin,Yuerong Yang,Yue Jia,Lujia Sun,Jie Liu,Langhong Wang,Fuxing Zhang,Wupeng Ge,Jiansheng Wang,Linjuan Huang,Zhongfu Wang
Goat milk oligosaccharides are complex carbohydrates with a variety of biological functions. Free oligosaccharides from goat milk show more similarity to human milk than cow milk. At present, changes in goat milk glycoconjugates at different parities remain poorly studied. Herein, we qualitatively and quantitatively compared the goat milk glycoprotein N/O-glycome at different parities using a stable isotope labeling followed by electrospray ionization mass spectrometry and online hydrophilic interaction chromatography. N-Glycans were mainly fucosylated and nonfucosylated nonsialylated, and both fucosylation and sialylation gradually increased with parity, amounting (at the third parity) to 1.25 times and 3.3 times those of the first parity, respectively. O-Glycans were mostly nonfucosylated and nonsialylated, and sialylation increased with increasing parity, and Neu5Ac-sialylated was up to 9 times higher in the third parity than in the first parity, whereas Neu5Gc-sialylated was 5.5 times higher. This study provides a reference for exploring an alternative milk source closest to human milk and for the development of humanized formula milk.
研究领域:
食品科学
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生物化学
·
营养学
✓ 已验证
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2022
·
IF 6.911
Yan Cai,Weifu Ren,Haiyan Wang,Qi Bian
Diabetic kidney disease (DKD) is a common and serious kidney-related complication of diabetic mellitus. Although albuminuria and estimated glomerular filtration rate (eGFR) are commonly used diagnostic biomarkers, they have limitations in the diagnosis of DKD due to the lack of specificity and sensitivity. Urinary N-glycans are emerging as novel biomarkers for predicting renal prognosis in DKD. However, most of the current N-glycan profiling methods for DKD were based on lectin affinity enrichment or hydrophilic interaction chromatography (HILIC) with optical detection, which provided limited N-glycome coverage in low throughput. Herein, we developed a novel N-glycan purification method, termed Ultrafast Glycoprotein Immobilization for Glycan extraction (UltraGIG), for in-depth profiling of urinary N-glycome in DKD using mass spectrometry (MS). In UltraGIG, proteins were rapidly (within 40 min) immobilized to resin with high efficiency (over 98%) through NHS-reactive chemistry , and then N-glycans were enzymatically released from the resin by PNGase F. Owing to good efficiency of immobilization of proteins to resin, the subsequent washing steps to remove proteins and other impurities could be easily performed. The UltraGIG showed good selectivity towards glycans (extracting N-glycans from the mixture of IgG and BSA at a 1:100 M ratio) and samples loss was minimized (detection sensitivity at fmol level). A total of 237 N-glycan compositions were identified from urine samples with DKD and healthy controls, which representing the largest data set of N-glycome from DKD. Compared to healthy controls, 3 N-glycans were up-regulated and 14 N-glycans were down-regulated in DKD patients. Collectively, UltraGIG offers a competitive sample purification method for in-depth analysis of urinary N-glycome by MS and provide new insights into biomarker study for the diagnosis of DKD.
研究领域:
医学
·
生物化学
✓ 已验证
DOI
PubMed
高影响因子
ENERGY & FUELS
·
2020
·
IF 3.421
Wei Zhao,Shanshan Ruan,Siyu Qian,Beibei Feng,Chengcheng Ao,Lei Wang,Fuyi Liu,Lidong Zhang
Catalytic combustion has become a promising technology to address the accelerating volatile organic compounds (VOCs) emissions. In this work, cobalt modified ZSM-5 zeolite catalysts (3–18 wt % Co) were prepared to investigate the combustion of n-butane (one typical model component of VOCs). The performances of catalysts were evaluated by conducting experiments in a flow tube reactor. XRD, BET, FT-IR, and XPS were also utilized to characterize their physicochemical properties. A significant enhancement of the catalytic activity was demonstrated in terms of the cobalt supported over ZSM-5, with an optimal cobalt loading of 7 wt %. The excellent catalytic activity of 7 wt % Co-ZSM-5 is mainly attributed to a higher concentration of active surface Co3+ species. Furthermore, DFT calculations indicated that the role of Co can enhance the activity by decreasing the activation barriers for C–H bond cleavage. In addition, the primary reaction mechanism of n-butane combustion on Co-ZSM-5 was also revealed.
研究领域:
环境科学
·
催化化学
✓ 已验证
DOI
高影响因子
SOLAR ENERGY MATERIALS AND SOLAR CELLS
·
2011
·
IF 4.746
Xiaolin Qiu,Wei Li,Guolin Song,Xiaodong Chu,Guoyi Tang
Microencapsulations of n-octadecane with different crosslinked methylmethacrylate-based polymer as shells were carried out by suspension-like polymerizations. 1,4-butylene glycol diacrylate (BDDA), divinylbenzene (DVB), trimethylolpropanetriacrylate (TMPTA) and pentaerythritol tetraacrylate (PETRA) were employed as crosslinking agents. The influences of the type and amount of crosslinking agent, the type of initiator and polymerization temperature on the properties of as-prepared microencapsulated phase change materials (MicroPCMs) have been studied. The MicroPCMs were characterized using Fourier transformed infrared (FTIR) spectroscopy and scanning electron microscopy (SEM). Thermal properties and thermal stability of MicroPCMs were investigated by differential scanning calorimetry (DSC) and thermalgravimetric analysis (TGA). Shell mechanical strength was measured by micro/nano-hardness tester. Thermal properties, thermal resistant temperatures as well as shell mechanical strength of MicroPCMs enhanced as the number of crosslinkable functional moieties of the crosslinking agents increased. The MicroPCMs containing 75.3 wt% n-octadecane obtained using PETRA as crosslinking agent has the highest latent heats of melting (156.4 J/g) and crystallization (182.8 J/g) and displays the highest thermal stability and shell mechanical strength. The MicroPCMs prepared with DVB shows a relatively higher shell mechanical strength and heat capacity compared with those prepared with BDDA. Both heat capacity and thermal stability of MicroPCMs prepared by combining 2,2 ′ -azobisisobutyronitrile (AIBN) and redox initiators at 45 °C were lower than that of MicroPCMs prepared with AIBN or benzoyl peroxide (BPO) at 85 °C. Hence, MicroPCMs with crosslinked methylmethacrylate-based polymer as shells, especially crosslinked polymer shells of higher crosslinking density , show a good potential as a solar-energy storage material.
研究领域:
材料科学
·
能源存储
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）