ACS Applied Materials & Interfaces
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2023
·
IF 9.5
Yanhua Ma,Dongzhi Zhang,Zihu Wang,Hao Zhang,Hui Xia,Ruiyuan Mao,Haolin Cai,Huixin Luan
Flexible strain sensors based on self-adhesive, high-tensile, super-sensitive conductive hydrogels have promising application in human–computer interaction and motion monitoring. Traditional strain sensors have difficulty in balancing mechanical strength, detection function, and sensitivity, which brings challenges to their practical applications. In this work, the double network hydrogel composed of polyacrylamide (PAM) and sodium alginate (SA) was prepared, and MXene and sucrose were used as conductive materials and network reinforcing materials, respectively. Sucrose can effectively enhance the mechanical performance of the hydrogels and improve the ability to withstand harsh conditions. The hydrogel strain sensor has excellent tensile properties (strain >2500%), high sensitivity with a gauge factor of 3.76 at 1400% strain, reliable repeatability, self-adhesion, and anti-freezing ability. Highly sensitive hydrogels can be assembled into motion detection sensors that can distinguish between various strong or subtle movements of the human body, such as joint flexion and throat vibration. In addition, the sensor can be applied in handwriting recognition of English letters by using the fully convolutional network (FCN) algorithm and achieved the high accuracy of 98.1% for handwriting recognition. The as-prepared hydrogel strain sensor has broad prospect in motion detection and human–machine interaction, which provides great potential application of flexible wearable devices.
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CATALYSIS COMMUNICATIONS
·
2023
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IF 3.7
Dan Luo,Qin Wang,Jiansu Ran,Ruixue Yangcheng,Yuntong Cui,Shuang Luo,Jianjian Wang
A series of Zr-based catalysts were prepared using various commercial and cheap organic acids as the coordination agents, and these as-synthesized samples exhibited superior activities to produce lactic acid (LaA) from carbohydrates. Using humic acid (HA) as a typical coordination agent, LaA yield was up to 76% over the resultant Zr-HA, outperforming the most recent reported works. Deeper studies revealed that Zr-HA possessed both acid sites and base sites, and these dual active sites can simultaneously activate xylose, resulting in high yield production of LaA. Besides, Zr-HA also showed excellent reusability and can be reused at least five times.
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JOURNAL OF CONTROLLED RELEASE
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2023
·
IF 10.8
Zhiwei Huang,Changju Chun,Xinze Li
The management of acute kidney injury (AKI) imposes a significant medical burden. Due to the lack of effective drug transport vehicles, the administration of therapeutic agents for AKI cannot obtain the desired therapeutic effects. Kidney-targeted nanoparticles for renal delivery of drugs have shown promising potential as an emerging strategy for AKI therapy. However, these exogenous nanoparticles are rapidly cleared in the body and fail to achieve the expected renal targeting efficiency. Herein, we prepared the kidney targeting peptide-modified renal tubular epithelial cell membrane to coat zeolite imidazolate framework-8 nanoparticles for FGF21 delivery ( [email protected] ) for AKI treatment. [email protected] could be efficiently internalized by renal cells and exhibited antioxidative, antiapoptotic and anti-inflammatory effects. A septic AKI murine model was established to assess the in vivo performance of [email protected] The results showed that injected [email protected] specifically accumulated in the injured kidney and exerted good renoprotective effects. This study provides an innovative thread for precise drug delivery in the treatment of various renal diseases.
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INDUSTRIAL CROPS AND PRODUCTS
·
2023
·
IF 5.9
Jingwen Sun,Yu Xie,Zhiyuan Chen,Yipin Fan,Yunfeng Liu,Qi Gao,Jianqiang Li,Jingwen Bai,Yu Yang
Magnolia officinalis root extract was obtained by high-pressure-assisted extraction, and the yield of honokiol (HNK) was 86.97 ± 1.05 mg/g dry power. The purified extracts and HNK inhibited the growth of methicillin-resistant Staphylococcus aureus (MRSA). Assays for alkaline phosphatases , proteins, nucleic acids leakage, and electrical conductivity, along with scanning and transmission electron microscopy measurements, confirmed the damaging effects of HNK on the cell wall and membrane of MRSA. Intake of sugar, protein production, molecular docking , and dynamic simulations revealed that HNK interfered with the transport of mannose-based carbohydrates by binding to VAL196, ILE291, ALA293, PRO294, and MET214 on the mannose transporter (ManP) in the phosphotransferase system, and thereby inhibited the carbohydrate metabolism of MRSA. These results indicated that HNK prevented MRSA from using carbohydrates by cutting off its nutritional process, and ultimately caused bacterial rupture and lysis. Therefore, ManP may be a potential target for HNK to combat MRSA infections.
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MOLECULES
·
2023
·Vol. 28
·期 9
·3881
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IF 4.6
Fengyi Wang,Ye Li,Chenglu Yan,Qiuting Ma,Xiaofeng Yang,Huaqiao Peng,Huiyong Wang,Juan Du,Baozhan Zheng,Yong Guo
The existence of carcinogenic nitrites in food and the natural environment has attracted much attention. Therefore, it is still urgent and necessary to develop nitrite sensors with higher sensitivity and selectivity and expand their applications in daily life to protect human health and environmental safety. Herein, one-dimensional honeycomb-like carbon nanofibers (HCNFs) were synthesized with electrospun technology, and their specific structure enabled controlled growth and highly dispersed bismuth nanoparticles (Bi NPs) on their surface, which endowed the obtained Bi/HCNFs with excellent electrocatalytic activity towards nitrite oxidation. By modifying Bi/HCNFs on the screen-printed electrode, the constructed Bi/HCNFs electrode (Bi/HCNFs-SPE) can be used for nitrite detection in one drop of solution, and exhibits higher sensitivity (1269.9 μA mM−1cm−2) in a wide range of 0.1~800 μM with a lower detection limit (19 nM). Impressively, the Bi/HCNFs-SPE has been successfully used for nitrite detection in food and environment samples, and the satisfactory properties and recovery indicate its feasibility for further practical applications.Keywords:nitrite sensor;honeycomb-like carbon nanofibers;Bi nanoparticles;nitrite detection
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MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Qi Nie,Jingjing Deng,Bing Xie,Tianshu Zhou
In this study, a novel solvent-assisted strategy was developed for the rapid and sensitive detection of kanamycin (KAN) based on glutathione-capped silver-doped gold nanoclusters (AuAg NCs). Ethanol solvent played a key role in disrupting the hydration shell of metal(I)-thiolate complexes in AuAg NCs. KAN, as a specific linker between AuAg NCs through electrostatic interaction and metal-amine coordination, induced the formation of large aggregates and thus triggered prolonged photoluminescence lifetime as well as strong luminescence enhancement by restricting molecular motions in AuAg NCs. The KAN-stimulated turn-on principle allows AuAg NCs to exhibit 4-fold sensitivity in 40% ethanol/water (V/V) mixed solution compared to that in water. The improved aggregation-induced-emission enhancement (AIEE) feature endows the AuAg NCs with selective recognition for KAN and realizes rapid detection in a short response time of 60 s with a low detection limit of 8.6 nM. By integrating AuAg NCs with a Pasteur pipette, a facile sample-to-answer test kit for on-site determination with low cost and high efficiency was constructed, offering potential applications in the timely analysis of contaminants in environmental emergencies.
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Gels
·
2023
·Vol. 9
·期 4
·318
·
IF 4.6
Xuejiao Ren,Xin Meng,Zhen Zhang,Hongyu Du,Tuoping Li,Na Wang
In this study, flaxseed gum (FG) was extracted using hot water extraction and ultrasonic-assisted extraction. The yield, molecular weight distribution, monosaccharide composition, structure, and rheological properties of FG were analyzed. The FG yield (9.18) achieved using ultrasound-assisted extraction (this sample was labeled as UAE) was higher than the yield (7.16) achieved with hot water extraction (this sample was labeled as HWE). The polydispersity, monosaccharide composition, and characteristic absorption peaks of the UAE were similar to that of the HWE. However, the UAE had a lower molecular weight and looser structure than the HWE. Moreover, zeta potential measurements indicated that the UAE exhibited better stability. An analysis of the rheological properties showed that the viscosity of the UAE was lower. Thus, the UAE had an effectively better yield of FG, preliminarily modified structure, and rheological properties, and provided a theoretical basis for its application in food processing.Keywords:flaxseed gum;ultrasound-assisted extraction;structural properties;rheological properties
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APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
·
2023
·Vol. 107
·期 5
·1725-1736
·
IF 5
Li Jing,Li Ziyi,Gong Hui,Ma Mengyi,Li Shuolei,Yang Huilin,Zhang Hailin,Liu Jianguo
Abstract In this study, a novel high-activity amylosucrase from Salinispirillum sp. LH10-3-1 (SaAS) was identified and characterized. The recombinant enzyme was determined as a monomer with a molecular mass of 75 kDa. SaAS protein exhibited the maximum total and polymerization activities at pH 9.0 and maximum hydrolysis activity at pH 8.0. The optimum temperature for total, polymerization, and hydrolysis activities were 40, 40, and 45 °C, respectively. Under the optimal pH and temperature, SaAS had a specific activity of 108.2 U/mg. SaAS also showed excellent salt tolerance and could retain 77.4% of its original total activity at 4.0 M NaCl. The addition of Mg 2+ , Ba 2+ , and Ca 2+ enhanced the total activity of SaAS. When the conversion of 0.1 M and 1.0 M sucrose was catalyzed at pH 9.0 and 40 °C for 24 h, the ratios of hydrolysis, polymerization, and isomerization reactions were 11.9:77.4:10.7 and 15.3:53.5:31.2, respectively. The α-arbutin yield of 60.3% was achieved from 20 mM sucrose and 5 mM hydroquinone catalyzed by SaAS. Key points
• A novel amylosucrase from Salinispirillum sp. LH10-3-1 (SaAS) was characterized.
• SaAS has the highest specific enzyme activity among all known amylosucrase.
• SaAS has hydrolysis, polymerization, isomerization, and glucosyltransferase activities.
Graphical Abstract
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2023
·
IF 10.9
Qi Chen,Xing Liu,Tingting Wang,Xiaogang Su,Meng Liu,Somboon Chaemchuen,Francis Verpoort
Exploring a simple, rapid, solvent-free synthetic method for mass production of cheap, broadband microwave absorbers remains the main challenge. Here, a mild solvent-free procedure is reported to synthesize zinc oxide nanoparticles (ZnO NPs) embedded in porous carbon derived from mixing sucrose and zinc nitrate hexahydrate. The characteristic morphology and the ZnO NPs distribution in these composites were tuned using the different raw materials proportions. The mesoporous structure of porous carbon benefits the compositional advantages between carbon foam and ZnO NPs. The optimal synthesized ZnO/C-2 carbon material demonstrates the strongest absorption of –41.7 dB with a frequency of 14.5 GHz at a thin thickness of 2 mm, and its widest effective absorption is close to 6 GHz (12.2–17.8 GHz). This work produces a feasible route for the sensible design of other effective microwave absorbers for large-scale production.
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CHEMOSPHERE
·
2022
·
IF 8.943
Rui Zhao,Xiufeng Cao,Xinxin Li,Tao Li,Hong Zhang,Xiaowei Cui,Zhaojie Cui
This study aimed to investigate the combined ecotoxicological effects of Cd, Pb, Zn, Hg and regulation mechanisms in Solanum nigrum L. In this work, the co-exposure of these four heavy metals hindered the transformation of Cd, Zn, and Hg (except Pb) from available to non-available chemical forms. Individual Cd, Pb, Zn and Hg induced the oxidative damages to S. nigrum L., while their combination further enhanced this ecological toxicity. By internal regulation, the ecological toxicity of metals to S. nigrum L. could be alleviated to a certain extent. Specifically, S. nigrum L. was a hyperaccumulator of Cd with BCF ＞1. Moreover, since BCFroot of Pb, Zn and Hg were all greater than BCFshoot, S. nigrum L. could accumulate Pb, Hg and Zn mainly in plant roots, which was beneficial for the detoxification of plants. Meanwhile, the immobilization by cell wall (the proportions of Cd, Pb, Zn and Hg in the cell wall were 54.46–84.92%, 38.33–49.25%, 48.38–56.19% and 45.97–63.47% in low metal concentration treatments) and the sequestration in vacuole (the proportions of Cd, Pb, Zn, and Hg in the soluble fractions are 50.99–59.00%, 41.05–45.46%, 37.54–61.04% and 33.47–61.35% in high metal concentration treatments) also act as important detoxification pathways. The external regulation was mainly the changes of soil microbial communities influenced by plants. Specifically, the richness and diversity of bacteria in rhizosphere soil were increased, and roots of S. nigrum L. recruited some potentially beneficial microbials. This study provided a theoretical basis and guidance for S. nigrum L. as a phytoremediation plant under combined heavy metal pollution.
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ANALYST
·
2022
·Vol. 148
·期 1
·146-152
·
IF 5.227
Jie Wang,Chenglong Zhao,Feijin Zhou,Hui Lu,Zhenhong Huang,Cheng Yao,Chan Song
The development of novel nanozymes is of great importance for the efficient analysis of biomolecules such as H2O2, glucose, and antioxidants in the diagnosis of some diseases. Herein, novel nanozymes based on Fe nanoparticles (NPs) encapsulated in 2D carbon nanosheets (denoted as Fe@CNs) were constructed and employed in the field of biosensing. Notably, Fe@CNs have intrinsic dual mimic enzyme properties. The colorless colorimetric substrate 3,3′,5,5′-tetramethylbenzidine (TMB) can be oxidized by Fe@CNs as oxidase- and peroxidase-like nanozymes, respectively. The generation of the oxidation state TMB (oxTMB) resulted from the presence of reactive oxygen species (ROS) which were produced by the catalytic decomposition of the dissolved oxygen or H2O2. Thus, a simple colorimetric biosensor was proposed to detect glutathione (GSH), H2O2, and glucose. In addition, the Fe@CN-based nanozymes also have excellent reusability in enzymatic catalysis. After separating from the sensing systems, Fe@CNs can be reused in other catalytic processes. This colorimetric method could be used as a universal sensing platform for the detection of antioxidants and H2O2-related bioanalysis. This work broadens the application of novel nanozymes in biosensing.
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Journal of Energy Chemistry
·
2022
·
IF 13.599
Fuyan Kang,Cai Shi,Yeling Zhu,Malin Eqi,Junming Shi,Min Teng,Zhanhua Huang,Chuanling Si,Feng Jiang,Jinguang Hu
The global commitment to pivoting to sustainable energy and products calls for technology development to utilize solar energy for hydrogen (H 2 ) and value-added chemicals production by biomass photoreforming. Herein, a novel dual-functional marigold-like Zn x Cd 1 -x S homojunction has been the production of lactic acid with high-yield and H 2 with high-efficiency by selective glucose photoreforming. The optimized Zn 0.3 Cd 0.7 S exhibits outstanding H 2 generation (13.64 mmol h −1 g −1 ), glucose conversion (96.40%), and lactic acid yield (76.80%), over 272.80 and 19.21 times higher than that of bare ZnS (0.05 mmol h −1 g −1 ) and CdS (0.71 mmol h −1 g −1 ) in H 2 generation, respectively. The marigold-like morphology provides abundant active sites and sufficient substrates accessibility for the photocatalyst, while the specific role of the homojunction formed by hexagonal wurtzite (WZ) and cubic zinc blende (ZB) in photoreforming biomass has been demonstrated by density functional theory (DFT) calculations. Glucose is converted to lactic acid on the WZ surface of Zn 0.3 Cd 0.7 S via the photoactive species O 2 − , while the H 2 is evolved from protons (H + ) in H 2 O on the ZB surface of Zn 0.3 Cd 0.7 S. This work paves a promising road for the production of sustainable energy and products by integrating photocatalysis and biorefine.
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