NEW JOURNAL OF CHEMISTRY
·
2016
·Vol. 40
·期 8
·7061-7067
·
IF 3.277
Li Qiang Yan,Zhi Neng Kong,Yong Xia,Zheng Jian Qi
Luminescent materials with aggregation-induced emission (AIE) properties have attracted considerable interest for their promising applications in light-emitting and display devices and fluorescent chemosensors. Coumarin and its derivatives are one of the most attractive chromophores due to their excellent properties, such as high fluorescence quantum yield, large Stokes shift, less toxicity, ease of modification and visible wavelength emission. A coumarin-based AIE-active red fluorogen was designed and synthesised. It was found that CDPA exhibits AIE property, red emission, self-assembly and thermally activated delayed fluorescence (TADF) in the solid state.
研究领域:
材料科学
·
光学
·
化学
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DOI
高影响因子
FOOD HYDROCOLLOIDS
·
2021
·
IF 9.147
Kaixuan Ma,Taotao Zhe,Fan Li,Yalan Zhang,Min Yu,Ruixia Li,Li Wang
Plastic pollution and food spoilage have drawn public attention, which may cause a great threat to the global environment and human health. Therefore, natural antimicrobial packaging has a pivotal share in solving these problems. In this study, biodegradable and antibacterial packaging films were successfully prepared via incorporating self-assembled berberine-cinnamic acid nanoparticles (BC NPs) into the film matrixes. With the addition of BC NPs, the UV-shielding property, hydrophobicity, and thermal stability of packaging were apparently improved. Meanwhile, the films also held considerable mechanical property and good biocompatibility, where the migrations of films in two food simulants were all far less than the permitted limits. Furthermore, nanocomposite films (NFs) exhibited strong antibacterial ability against both E. coli and S. aureus . By measuring the fluorescence spectrum and ROS production of films, we certificated NFs were AIE-active, and the antimicrobial activity of NFs was significantly enhanced under white light. Finally, the packaging test further indicated NFs could inhibit microbial growth of chicken samples well. The sustainable NFs will be ideal candidate materials to replace plastics and extend the shelf life of food products.
研究领域:
材料科学
·
生物学
·
食品安全
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DOI
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
·
2019
·
IF 2.781
Hongtao Wu,Furong Tao,Yuezhi Cui,Li Guo
Two tiphenylamine-based materials SM-1 and SM-2 were synthesized via simple one-step synthetic progress, which exhibits aggregation induced emission (AIE) in DMSO/H 2 O (1/9, v/v) solution due to intermolecular interactions and the restriction of intramolecular rotation in the aggregated state. The relationships between their structures and photophysical properties were studied via spectroscopic methods and density functional theory (DFT) calculations. The single crystal data of SM-1 and SM-2 revealed that multiple intermolecular interactions between molecules. Due to the excellent AIE nature of the two compounds. SM-1 and SM-2 were highly sensitive toward PA in the aggregated state. The quenching constant ( K SV ) of SM-2 was 5.33 × 10 4 M −1 , and SM-1 was 1.1 × 10 5 M −1 , with limit of detection (LOD) were 1.9 μM and 93 ppb for SM-1 and SM-2, respectively. For this reason, it shows that AIE materials are promising candidate in detection of explosives.
研究领域:
化学
·
材料科学
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DOI
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2021
·Vol. 37
·期 1
·143-149
·
IF 1.307
Shen Qifei,Xu Ruohan,Wang Zhi,Zhao Tianyu,Zhou Yu,Xu Yanzi,Yang Zhiwei,Lei Ming,Meng Lingjie,Dang Dongfeng
Aggregation-induced emission(AIE) luminogens(AIEgens) with high brightness in aggregates exhibit great potentials in biological imaging, but these AIEgens are seldom applied in super-resolution biological imaging, especially in the imaging by using the structural illumination microscope(SIM). Based on this consideration, we synthesized the donor-acceptor typed AIEgen of DTPA-BTN, which not only owns high brightness in the near-infrared(NIR) emission region from 600 nm to 1000 nm(photoluminescence quantum yield, PLQYs=11.35%), but also displays excellent photo-stability. In addition, AIE nanoparticles based on 4,7-ditriphenylamine-[1,2,5]-thiadiazolo[3,4-c]pyridine(DTPA-BTN) were also prepared with highly emissive features and excellent biocompatibility. Finally, the developed DTPA-BTN-based AIE nanoparticles were applied in the super-resolution cellular imaging via SIM, where much smaller full width at half-maximum values and high signal to noise ratios were obtained, indicating the superior imaging resolution. The results here imply that highly emissive AIEgens or AIE nanoparticles can be promising imaging agents for super-resolution imaging via SIM.
研究领域:
生物医学成像
·
材料科学
·
光学显微技术
✓ 已验证
DOI
高影响因子
Small
·
2024
·
IF 13
Ke Ma,Jianxia Dong,Dingyuan Yan,Deliang Wang,Yuanwei Wang,Jianxing Wang,Dong Wang,Hui Tan,Ben Zhong Tang
Developing versatile photosensitizers to actualize selective antibacteria over normal cells presents an appealing yet significantly challenging task. In this study, a novel photosensitizer named DMMA-SCPI is rationally designed and facilely synthesized, which is demonstrated as a type-I photosensitizer featured by aggregation-induced emission tendency. DMMA-SCPI is capable of effectively eliminating both Galanz positive bacteria and Galanz negative bacteria in vitro and in vivo, and showed insignificant injury to normal cells and tissues, probably resulting from its pyridinium halide that has stronger adsorption property on negatively charged bacteria compared to normal cells, as well as its suitable antimicrobial activity. The antimicrobial activity of pyridinium salt type photosensitizer depends on the adsorptive activities on the surface of bacterial cells as well as the antimicrobial activity of the reactive oxygen species (ROS). Among three photosensitizers, DMMA-SCPI has better water solubility, which provides greater surface activity to adsorb bacteria. Moreover, DMMA-SCPI produces more superoxide anion radicals as ROS, which has proper antimicrobial activity with high biosafety for effect extracellular antibacteria.
研究领域:
分子工程
·
生物医学
·
光动力疗法
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Jing Liu,Shasha Yang,Qi Liu,Jie Wang,Yongchang Mu,Yingchun Li,Jie Li
Aggregation-induced emission (AIE) hydrogels have been widely applied in the field of information security due to their tunable optical properties and aggregation-induced emission properties. The introduction of spiropyranoid organic fluorescent dyes with multi-stimulus response into AIE hydrogels will endow them more functions. However, the traditional 2D anti-counterfeiting has the problem that the hidden information is easy to be copied. Therefore, it is urgent to develop a new anti-counterfeiting strategy to improve the level of information security. In this study, we present for the first time a new strategy of combining multi-stimulus response AIE fluorescent hydrogels with shape memory polyurethane to apply them in the field of information security. The polymer skeleton of fluorescent hydrogel (PCHS hydrogel) is composed of polyvinyl alcohol (PVA) and carboxymethyl chitosan (CMCS) through hydrogen bonding. Four [4-(3, 5-dicarboxyphenyl)] tetraphenyl ethylene (H 8 ETTB) and 1- (2-hydroxyethyl) −3, 3-dimethylindolin-6 ’-nitrobenzo spiropyrone (SP) are chosen as the fluorescent fillers. PCHS hydrogel is printed onto shape memory polyurethanes (SMPU) by a flexible electronic printer. As a result, the hidden information printed on the SMPU needs to be decrypted at temperatures (80 ℃) and under ultraviolet irradiation(365 nm). Moreover, the hidden information can be destroyed by adding H + or applying external force after heating to 80 ℃. This effectively improves the security of the information and prevents its disclosure. Interestingly, we can choose the destruction method to make the destruction of information more flexible. This strategy has great potential in the field of information encryption and anti-counterfeiting.
研究领域:
材料科学
·
信息加密
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 8.3
Chenlu Chen,Yaxin Han,Yuxin Hu,Jing Mu,Jingyi Zhu,Fuyuan Huang,Lin Zhang,Yayun Jiang,Laibao Zheng
Antimicrobial resistance (AMR) poses a major threat to global public health, underscoring the urgent need for rapid phenotypic antimicrobial susceptibility testing (AST) to guide timely antibiotic therapy. With this in mind, we have designed a copper metabolism-responsive fluorescence sensing platform based on dendritic mesoporous silica-confined aggregation-induced emission (AIE) gold nanoclusters (DMSN@GSH-AuNCs, DA) for rapid bacterial detection and AST. In this sensing system, Cu 2 + effectively quenches the fluorescence of DA through coordination interactions, whereas bacteria can metabolically consume Cu 2+ to varying degrees, attenuating the quenching effect and generating a metabolism-dependent fluorescence signal. Compared with free AuNCs, the confined DA platform exhibits enhanced fluorescence quenching responsiveness, enabling more sensitive readout of bacterial metabolic activity. By coupling this response with antibiotic-induced metabolic inhibition, the platform allows discrimination between susceptible and resistant bacteria within 2 h. Notably, distinct signal responses were observed for representative Gram-negative and Gram-positive bacteria, indicating the broad applicability of this sensing strategy. In validation with 17 clinical Escherichia coli isolates, the method achieved high diagnostic performance, with area under the receiver operating characteristic curve (AUC) values of 0.958 and 0.950 for gentamicin and ciprofloxacin, respectively. These results demonstrate that the Cu 2+ -DA platform provides a rapid, sensitive, and operationally simple strategy for phenotypic AST and holds considerable promise for improving early antimicrobial stewardship.
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Tong-Tong Jia,Jia-Yu Li,Yingying Zheng,Tao Fu,Cuicui Li,Jian-Hua Qin,Huawei Niu
Benzoyl peroxide (BPO), a banned but illegally used flour additive, poses serious health risks. Current detection methods face challenges in on-site applications due to instrument dependency and complexity. We developed an aggregation-induced emission (AIE) fluorescent probe ( NMYF ) for rapid, selective, and visual BPO detection. NMYF exhibits fast fluorescence quenching (<1 min), a low detection limit (0.91 μM), and high selectivity. Integrated into polyamide films and agarose gels, NMYF enables portable sensing platforms. Using smartphone-based RGB analysis, on-site BPO quantification was achieved with detection limits of 66.9 μM ( NMYF -films) and 7.09 μM ( NMYF -gels). NMYF -gels successfully detected BPO in wheat flour, noodles, and noodle sheets, with recoveries of 93.08–116.12% and RSDs below 8.75%. In addition, NMYF performed excellently on various substrates in latent fingerprint imaging, displaying Level 1–3 fingerprint details with high clarity. The bifunctionality of NMYF highlights its potential in both food safety and forensic science.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2025
·
IF 6
Long Zhang,Manyu Xue,Qi Xin,Jie Tang,Yin Liu,Zhengyang Bian,Xiaoping Zheng
The increasing prevalence of nanoplastics (NPs) in the environment has raised significant concerns about their potential for bioaccumulation and toxicity. However, most toxicity studies currently focus on pristine polystyrene NPs (PSNPs), overlooking the impact of environmental weathering on their surface chemistry and interactions with biological systems. This study adopts an aggregation-induced emission (AIE)-based approach to quantify how surface functionalization affects cellular uptake, a critical step in assessing NPs toxicity. We synthesized carboxyl (-COOH) and amino (-NH 2 ) functionalized PSNPs through emulsion polymerization, incorporating an AIE fluorescent label to enable precise quantification and to distinguish the NPs from endogenous biomolecules. Using mouse macrophages (RAW264.7) as a model, we demonstrated that surface carboxylation significantly enhanced cellular uptake compared to the original NPs. This enhanced uptake effect is likely due to the increased interaction between the functionalized NPs and the cell surface receptors. Quantitative fluorescence analysis and flow cytometry revealed that PSNP-COOH exhibited the highest uptake and the most pronounced effects on cell toxicity. This AIE-based approach offers a more environmentally relevant model for evaluating NPs toxicity, understanding the importance of considering surface modifications when assessing the biological effects of NP exposure.
研究领域:
环境科学
·
生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TETRAHEDRON
·
2025
·
IF 2.2
Qian Wu,Peng Yang,Zhijun Ke,Hanwen Wang,Zehua Zhang,Boyi Zhang,Shenglin Li,Xiaoping Rao
The utilize of epoxy resins always necessitates the aid of petroleum-based curing agents to facilitate cross-linking and engender an irreversible tridimensional network structure. However, this characteristic, in turn, imposes the constraint of recyclability in their applications and hinders sustainable development. Creating a durable and repeatedly useable epoxy resin adhesive that can withstand mild bonding conditions lingers a significant challenge. In this work, a novel rosin-based epoxy resin (HAR-EP x ) was successfully prepared from hydrogenated acrylic rosin (HAR) and epoxy resin (EP x ) based on the structure of the hydrogenated phenanthrene ring with large steric hindrance and low cross-linking density. The HAR-EP x prepared in this study exhibits several remarkable properties, such as outstanding heat resistance (T d = 354 °C), exceptional UV–visible light transmittance. HAR-EP x can be applied to adhesives without curing agents, and was characterized by mild bonding conditions (85 °C, 1.5 min), high mechanical properties (adhesion strength up to 4.306 MPa), and excellent reusability that retains over 80 % bonding strength even after undergoing 6 cycles. Moreover, it exhibits an intriguing characteristic, that is, it emits intrinsic cyan-green fluorescence when subjected to UV excitation, attributed to aggregation-induced emission (AIE).
研究领域:
材料科学
·
可持续发展
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产品关联
DOI
高影响因子
BIOMATERIALS
·
2019
·
IF 10.273
Youmei Li,Qian Wu,Miaomiao Kang,Nan Song,Dong Wang,Ben Zhong Tang
Photosensitizers with aggregation-induced emission (AIE) characteristics are of great interest for cancer theranostics involving both fluorescence imaging and photodynamic therapy (PDT). However, in the purpose of clinical trials of PDT, the development of prominent drug delivery systems for boosting the PDT efficiency of AIE photosensitizers is highly desirable but still remain a challenging task. Herein, a novel strategy is designed and performed for boosting PDT effect based on stimuli-responsive nano-micelles as extraordinary carriers for an AIE photosensitizer, namely MeTTMN. Those presented stimuli-responsive nano-micelles loading MeTTMN exhibit good biocompatibility , excellent stability, appropriate nanoparticle size, high loading efficiency, outstanding imaging quality and significantly promoted PDT performance, eventually making them remarkably impressive and significantly superior to commercially available nano-micelles carried MeTTMN. This study thus offers an ideal template for fluorescence imaging-guided PDT, as well as a promising candidate for clinical trials.
研究领域:
生物医学工程
·
肿瘤学
·
药剂学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Polymer Chemistry
·
2025
·
IF 3.9
Xuehui Liu,Qian Li,Ranran Gao,Qu Wang,Li Wang,Wantai Yang
Macromolecular architecture control of fluorescent polymers presents an important approach to diverse self-assembled nanostructures and tailored functions. Herein, tetraphenylethylene (TPE) derivatives with different bromopropionate and hydroxyl functionalities were synthesized efficiently. Based on the single electron transfer living radical polymerization (SET-LRP) of oligo(ethylene glycol) methyl ether acrylate (OEGA) and the mechanistic transition to reversible addition−fragmentation chain transfer (RAFT) dispersion polymerization of benzyl methacrylate (BzMA), well-defined aggregation-induced emission (AIE)-active miktoarm star TPE-(POEGA)n-(PBzMA)4-n (n = 1−3) nanoassemblies were synthesized for the first time. The nanoassemblies were utilized as an ideal platform to probe the intricate interplay between macromolecular architecture, self-assembly behavior, and fluorescence properties. Results showed that the arm engineering (changing the respective arm numbers) of miktoarm star polymers can bring about drastic alterations in the self-assembled morphology and photoluminescence characteristics. This arises from the influences of macromolecular structure on molecular packing, intermolecular interactions and intramolecular motions. This work highlights the unique advantage of miktoarm star architecture design and has far-reaching implications for the rational design of high-performance intelligent fluorescence systems.
研究领域:
高分子化学
·
材料科学
·
纳米技术
·
荧光材料
·
自组装
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）