Small
·
2025
·
IF 12.1
Qian Kong,Chengcheng Yu,Qing Lu,Xingyu Yang,Tongguang Xu,Qi Song,Huatong Li,Zhaoshuo Yuan,Hongyu Liu,Qian Qiao,Gang He,Yufan Wang,Linglong Yao,Xiaoping Dai,Xin Zhang
The electrolysis of water for hydrogen production has gained increasing attention as a sustainable and efficient method to obtain high-purity green hydrogen. The development of efficient catalysts for hydrogen evolution is crucial in order to achieve this target under industrial conditions. The objective of this work is to synthesize a highly efficient F-Co x Fe y (PO n ) z /IF catalyst with ultra-low impedance for hydrogen evolution in electrolytic water by incorporating metal phosphatides into metal oxide nanoclusters through a controlled two-step process involving melting and electrodeposition. The nano-heterostructure of F-Co x Fe y (PO n ) z /IF exhibits a low overpotential of 276 mV at a current density of 1000 mA cm −1 , while having an electrochemical impedance comparable to commercial Pt/C/CP (0.41 Ω), and long-term stability up to 200 h in 1 M KOH electrolyte. The synergistic effect of crystal/amorphous heterojunctions, F doping, and oxygen vacancies further enhances the kinetics of water cracking. Impressively, when combined with NiFeCo LDH/NiS/NF as membrane electrodes, F-Co x Fe y (PO n ) z /IF || NiFeCo LDH/NiS/NF achieves a water decomposition voltage of 2.03 V at a current density of 1000 mA cm −2 and demonstrates stable operation for over 500 h, showing great potential for large-scale commercial production.
研究领域:
电化学
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催化
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材料科学
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氢能
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纳米技术
·
能量转换
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产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2021
·Vol. 26
·期 5
·1303
·
IF 4.412
Yingda Zang,Ke Liu,Weiping Wang,Chuangjun Li,Jie Ma,Jingzhi Yang,Xinyi Chen,Xiaoliang Wang,Dongming Zhang
The multifactorial nature of Alzheimer’s disease (AD) calls for the development of multitarget agents addressing key pathogenic processes. A total of 26 Claulansine F–donepezil hybrids were designed and synthesized as multitarget drugs. Among these compounds, six compounds exhibited excellent acetylcholinesterase (AChE) inhibitory activity (half maximal inhibitory concentration (IC50) 1.63–4.62 μM). Moreover, (E)-3-(8-(tert-Butyl)-3,3-dimethyl-3,11-dihydropyrano[3,2-a]carbazol-5-yl)-N-((1-(2-chlorobenzyl)piperidin-4-yl)methyl)acrylamide (6bd) exhibited better neuroprotective effects against OGD/R (oxygen–glucose deprivation/reoxygenation) than lead compound Claulansine F. Furthermore,6bdcould cross the blood–brain barrier in vitro. More importantly, compared to edaravone,6bdhad stronger free-radical scavenging activity. Molecular docking studies revealed that6bdcould interact with the catalytic active site of AChE. All of these outstanding in vitro results indicate6bdas a leading structure worthy of further investigation.Keywords:Alzheimer’s disease;Claulansine F–donepezil hybrids;AChE inhibitory activity;free-radical scavenging activity;neuroprotective effects
研究领域:
药理学
·
神经科学
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2025
·
IF 4.3
Zhaohua Jiang,Shiyuan Fan,Huiting Xu,Huibin Liu,Sai Dong,Jing Li,Xiaoteng Yan,Zhijie Cui,Wenchao Peng,Wen Liu,Jiapeng Liu
Aqueous copper-selenium (Cu-Se) battery based on conversion mechanism have garnered interest due to their intrinsic safety features and high specific capacity. However, the slow conversion kinetics presents a challenge for its development. Herein, catalytic host material of NbSe 2 @few-layered Nb 2 C (NbSe 2 @f-Nb 2 C) heterostructure with built-in electric field (BIEF) is prepared by in situ selenization strategy for aqueous Cu-Se battery. Benefiting from the high electrical conductivity of f-Nb 2 C MXene, the high electrocatalytic performance of NbSe 2 and the spontaneous BIEF between NbSe 2 and f-Nb 2 C MXene, the Se redox reactions kinetics is enhanced and the reaction barrier is reduced. Consequently, the specific capacity of Se/NbSe 2 @f-Nb 2 C cathode can reach 1128 mAh g −1 at 0.25 A g −1 with stable cycling performance. Additionally, the conversion mechanism is investigated via comprehensive characterizations and density functional theory calculations. This study provides an innovative approach for designing high performance MXene-based catalytic host materials to enhance the conversion kinetics of aqueous Cu-Se batteries.
研究领域:
储能
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材料科学
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电化学
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纳米技术
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电池技术
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产品关联
DOI
高影响因子
ACS Omega
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2020
·
IF 2.87
Ning Song,Shao-Peng Chen,Xiao-Wei Fan,Yu-Hui Tan,Wen-Juan Wei,Yun-Zhi Tang
The molecular design and regulation has shown bright future for constructing smart molecular materials such as ferroelectrics, dielectric switches, electro-optic effect, and so forth. Here, by poly-H/F substitution in a simple organic-inorganic hybrid 2[CH2FCH2NH3]·[CdCl4], 1 (CH2FCH2NH3 = fluorine ethylamine cation), we obtained two novel hybrids, namely, 2[CHF2CH2NH3]·[CdCl4], 2 (CHF2CH2NH3 = 2,2′-difluorine ethylamine cation) and 2[CF3CH2NH3]·[CdCl4], 3 (CF3CH2NH3 = 2,2′,2″-trifluorine ethylamine cation). Further investigations show that compounds 1, 2, and 3 experience solid reversible phase transitions with temperatures at 294, 319, and 329 K respectively. These unique phase transitions were confirmed by their remarkable dielectric and heat anomalies around the phase transition temperatures. X-ray single-crystal diffraction analyses before and after the phase transitions show that the order–disorder motions of F atoms and the twist motions from the 2D [CdCl4]2– framework lead to these solid reversible phase transitions. Also, the Hirshfeld surface calculation of compounds 1, 2, and 3 suggests that the increasing ratio of the F···F interaction from the intermolecular interaction makes a major contribution for the substantial increase of their phase transition temperatures.
研究领域:
材料科学
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化学
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晶体学
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分子设计
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2025
·
IF 13.2
Zhikun Wang,Zhihua Zhao,Chen Chen,Guixin Jin,Xiaoqing Shen,Zhigang Shao,Lan Wu
Environmental safety monitoring has significantly benefited from the incorporation of gas sensors. Given the pernicious effects of ammonia and acetic acid gases on the environment and human health, it is imperative to develop a room temperature dual-functional gas sensor capable of simultaneously detecting both these gases. In this research endeavor, acid-functionalized multi-walled carbon nanotubes (f-MWCNTs) were integrated with Bi 2 S 3 through a hydrothermal approach, leading to the fabrication of a Bi 2 S 3 /f-MWCNTs-2 nanocomposite-based chemoresistive gas sensor. The results demonstrate that the Bi 2 S 3 /f-MWCNTs-2 sensor exhibits a response value of 52.7 % towards 100 ppm NH 3 at room temperature (25℃), displaying a declining resistance curve upon exposure to the target gas. Similarly, for 100 ppm CH 3 COOH under ambient conditions (25℃), the sensor records a response value of 72.55 %, accompanied by a rising resistance curve when in contact with CH 3 COOH gas. The distinctive feature of this dual-functional sensor lies in its ability to detect opposing transient response curves for the two gases, which is crucial for distinguishing between different gases. Furthermore, the sensor boasts swift response recovery, excellent repeatability, and robust stability. This study underscores the promising potential of the Bi 2 S 3 /f-MWCNTs-2 nanocomposite sensor in applications such as environmental monitoring.
研究领域:
材料科学
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环境科学
·
传感器技术
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产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2024
·
IF 8.1
Ying Qi,Huaming Yang,Chunli Li,Hao Li
During the storage/transportation of fruits and vegetables, ethylene-induced over-maturation and spoilage is a serious problem. Currently developed ethylene adsorbents exhibit great potentials due to their low cost and high efficiency, but always lack of water resistance. Herein, we developed Ag/F-Z5(X) adsorbents via the modification of ZSM-5 with different amounts of NH 4 F followed by silver loading, which exhibits enhanced ethylene adsorption and water resistance. Among the samples, Ag/F-Z5(25) featured with the largest capacity (6.44 mg·g −1 ) and the best water resistance, achieving near-complete removal of trace ethylene (100 ppm) at room temperature. Based on the characterizations, NH 4 F modification induced a hierarchical structure within the ZSM-5 framework, concurrently enhancing surface acidity, increasing the proportion of Ag + , and improving the dispersion of metals in the adsorbents. These enhancements collectively contribute to enhanced adsorption and water resistance. Further, banana storage experiments confirmed the actual preservation ability of Ag/F-Z5(25) thanks to the better adsorption and water resistance than unmodified Ag/Z5. These findings offer meaningful insights for developing high-efficient and water-resistant adsorbents to remove trace ethylene, consequently mitigating food aste and enlarging the commercial value of agricultural products.
研究领域:
农业工程
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食品科学
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材料科学
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2019
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IF 8.456
Chao Yang,Na Han,Changye Han,Menglu Wang,Wenxin Zhang,Weijing Wang,Zongxuan Zhang,Wei Li,Xingxiang Zhang
Extremely asymmetric wettability, high wetting selectivity, instantaneous superwetting behaviors (low transmembrane resistance), and superior resistance to chemicals and solvents are needed for Janus membranes for switchable oil/water separation. However, it is still challenging to obtain Janus membranes with such properties. In this study, a surface with metastable hydrophobicity is constructed on one side of the chemically stable superhydrophilic TiO2@PPS membrane by adjusting the hydrophobization depth and the morphology of the hydrophobic layer via a water–oil interfacial grafting. The prepared Janus membrane exhibits a high water contact angle difference of ∼150° between its two surfaces with maintaining the superior penetrability of the original membrane, which makes it capable to separate both oil-in-water and water-in-oil emulsions with high fluxes and accuracy. The separation efficiency is higher than 98% for the separation of the two kinds of emulsions. The fluxes of the surfactant-free toluene-in-water and water-in-toluene emulsions are up to 6.4 × 102 and 9.5 × 102 L m–2 h–1, respectively. Furthermore, the Janus membrane exhibits desirable antifouling performance and reusability during usage.
研究领域:
材料科学
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环境工程
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化学工程
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产品关联
DOI
PubMed
高影响因子
Water
·
2025
·Vol. 17
·期 15
·2261
·
IF 3
Xiangyu Chen,Hao Zhong,Juanjuan Yao,Jingye Gan,Haibing Cong,Tengyi Zhu
Fibrate pharmaceuticals (fibrates), as a widespread class of emerging contaminants, pose potential risks to both ecological systems and human health. The photocatalytic system based on nitrogen (N) and fluorine (F) co-doped TiO2nanotube arrays (NF-TNAs) provides a renewable solution for fibrate pharmaceutical removal from water, powered by inexhaustible sunlight. In this study, the degradation of two typical fibrates, i.e., bezafibrate (BZF) and ciprofibrate (CPF), under simulated sunlight irradiation through NF-TNAs were investigated. The photocatalytic degradation of BZF/CPF was achieved through combined radical and non-radical oxidation processes, while the generation and reaction mechanisms of associated reactive oxygen species (ROS) were examined. Electron paramagnetic resonance detection and quenching tests confirmed the existence of h+, •OH, O2•−, and1O2, with O2•−playing the predominant role. The transformation products (TPs) of BZF/CPF were identified through high-resolution mass spectrometry analysis combined with quantum chemical calculations to elucidate the degradation pathways. The influence of co-existing ions and typical natural organic matters (NOM) on BZF/CPF degradation were also tested. Eventually, the ecological risk of BZF/CPF transformation products was assessed through quantitative structure–activity relationship (QSAR) modeling, and the results showed that the proposed photocatalytic system can largely alleviate fibrate toxicity.
研究领域:
环境科学
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材料科学
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药物污染
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光化学
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水处理技术
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产品关联
DOI
高影响因子
Biomaterials Science
·
2020
·Vol. 9
·期 6
·2009-2019
·
IF 6.183
Y. D. Chen,C. Shu,Z. H. Duan,J. J. Xu,X. J. Li,F. Chen,Q. J. Luo,X. D. Li
Dental caries have become a major global public health problem. Plaque control and remineralization of initial enamel lesions are paramount for the prevention and control of caries. Polyhexamethylene biguanide (PHMB) is a type of cationic amphipathic antibacterial agent with broad-spectrum antibacterial properties and good biological safety. Fluoride delays demineralization and promotes the remineralization of hard dental tissues. However, a high concentration is needed for it to function as an antibacterial agent. In order to create a PHMB with the benefits associated with fluoride, we synthesized a fluorine-containing cationic polymer, PHMB-F. Fourier transform-infrared spectroscopy and solid state nuclear magnetic resonance characterization confirmed the successful synthesis of PHMB-F. Antibacterial tests showed that PHMB-F had better antiseptic efficacy for Streptococcus mutans compared with just PHMB. Moreover, positively-charged PHMB-F allows fluoride ions to exist closer to the enamel surface with negative potential, which markedly lowers the ion concentrations in the microenvironment adjacent to hard dental tissues needed to maintain equilibrium. Thus, only low concentrations of PHMB-F are required for enamel remineralization.
研究领域:
牙科学
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材料科学
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药物化学
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DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
·
2025
·
IF 4.7
Yu Kang,Bin Li,Haoyu Li,Yuxiao Guo,Qiange He,Li Wang,Guo Wang,Xiaoyan Tang,Chao Xu
The design of multidentate hydrophilic ligands with high binding affinity and selectivity is fundamentally important for efficient metal separation and the development of highly stable radiopharmaceuticals. A widely adopted strategy involves introducing water-solubilizing groups into originally effective lipophilic ligands, aiming to preserve the metal-binding affinity while imparting aqueous solubility. In this work, we demonstrate that such an intuitive solubilization approach can fail if an appropriate hydrogen-bonding network is not established. Using a phenanthroline diimine ligand system as a model, we reveal, at a molecular level, how inter- and intramolecular hydrogen bonding critically influences both water solubility and metal affinity. This is supported by a comprehensive suite of spectroscopic titrations, single-crystal X-ray diffraction, and DFT calculations. To the best of our knowledge, this is the first in-depth study to correlate molecular structure and hydrogen-bonding interactions with overall ligand solubility and metal affinity/selectivity. The insights gained here offer valuable guidance for the rational design of hydrophilic ligands in applications ranging from nuclear waste remediation to f-block-metal-based radiopharmaceuticals and contrast agents.
研究领域:
无机化学
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配位化学
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物理化学
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核化学
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材料科学
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药物化学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Wenfeng Han,Jinchao Wang,Lulu Chen,Luteng Yang,Shucheng Wang,Miao Xi,Haodong Tang,Wucan Liu,Weiyu Song,Jianjun Zhang,Ying Li,Huazhang Liu
Trifluoromethane is one of the most potent and stable greenhouse gases with global warming potential of 14,800 times higher than CO 2 (100-year time horizon). At present, it is destroyed by incineration or plasma at temperatures above 1200 K. For the first time, this work report that CHF 3 can be reverted to HCFC-22 via the intermolecular Cl/F exchange reaction of CHF 3 with CHCl 3 over AlF 3 catalyst under moderate conditions. As CHF 3 is produced during the manufacture of HCFC-22 via the fluorination of CHCl 3 in liquid phase, no additional feedstock and products are involved for the treatment of CHF 3 in this proposed process. At 593 K and atmospheric pressure, CHF 3 conversion levels of about 18%–20% are achieved and no significant deactivation is observed following time on stream of 100 h. In addition, the catalytic reaction mechanism is proposed. According to the experiments and DFT calculation, the intermolecular Cl/F exchange reaction of CHF 3 with CHCl 3 is mainly initiated by the breakage of C Cl. The present work provides a potential resource utilization route for the treatment of CHF 3 and other hydrofluorocarbons (HFCs).
研究领域:
化学
·
环境科学
·
催化
·
绿色化学
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Yang Li,Jia-Jia Li,Qing Zhang,Jian-Yong Zhang,Na Zhang,Yong-Zheng Fang,Jinwu Yan,Qinfei Ke
The highly emissive BODIPY (boron-dipyrromethene) have been grafted on the Eu-based metal-organic frameworks (Eu-MOFs) via the covalent F-B bonding using a facile one-pot solvothermal reaction. The fluorescence emission ratio of [email protected] has been applied to construct the ratiometric fluorescence sensor for the F - , H 2 O 2 and glucose detection in water solution and living cells. The produced [email protected] probe provided enhanced sensitivity, higher selectivity and lower lower limits of detection (LOD) for the detection of F - (0.1737 μM), H 2 O 2 (6.22 nM) and glucose (6.92 nM), and 5.96, 6.52 and 6.95 times lower than that for single Eu-MOF, respectively. More importantly, the probe also exhibited the lower biotoxic in living cells for bioimaging and the better visualization performance with multiplex channels. The results indicated the π-conjugated BODIPY derivative not only acted as the surfactant molecule or template agent for preferred growth, but also modulated the fluorescent emissions drastically, and thus induced excellent fluorescent detecting performances.
研究领域:
纳米技术
·
分析化学
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生物医学工程
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生物化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）