CHEMICAL ENGINEERING JOURNAL
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2022
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IF 16.744
Jie Li,Zhuobiao Ni,Qiongzhi Gao,Xixian Yang,Yueping Fang,Rongliang Qiu,Mingshan Zhu,Shengsen Zhang
Glyphosate is a widely used herbicide in agriculture. Its residues pose a great threat to ecological balance and human health. The potential impact of glyphosate and its by-products on the soil and water environment is of great concern. Here, a core–shell structured cobalt–nickel bimetallic sulfide NiCo 2 S 4 /Co 9 S 8 /NiS (NCS) is synthesized by a simple two-step hydrothermal method, and used as a novel peroxymonosulfate (PMS) activator for degradation of glyphosate. The effects of various reaction conditions on the degradation of glyphosate in the NCS-PMS system are investigated. The NCS is used to activate PMS by the dual redox cycle of Co 2+ /Co 3+ and Ni 2+ /Ni 3+ under its core–shell structure to efficiently degrade glyphosate. The optimized NCS achieved 82.2 % removal of 10 -4 mol⋅L -1 glyphosate in 35 min with an initial pH = 3.9. The removal performance is 25.7 and 1.5 times higher than that of monometallic sulfides Ni 3 S 2 /NiS and Co 3 S 4 prepared by the same process of NCS, respectively. The radical quenching experiments reveal that NCS interacted with PMS to generate SO 4 •− and •OH radicals, O 2 •− as well as 1 O 2 together to achieve efficient degradation of glyphosate. The main intermediates of glyphosate degradation by NCS-activated PMS are identified by liquid chromatography-quadrupole time-of-flight mass spectrometry, and possible degradation pathways of glyphosate are proposed and the relative toxicity of degraded products is evaluated. This work provides a novel insight to produce high-performance multiphase catalysts for glyphosate degradation as well as practical applications.
研究领域:
环境科学
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农业科学
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DOI
高影响因子
FOOD CHEMISTRY
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2022
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IF 9.231
Jianping Guan,Qing He,Qi Liu,Xiaoqing Chen
Herein, by employing a novel synthesized ligand H 2 L, a flower-like luminescent metal–organic framework IRMOF-3-L was constructed for developing a triple-mode sensor for glyphosate (Glyp) detection. The ligand H 2 L was designed to contain three functional parts, which endowed the resulted IRMOF-3-L with peroxidase-like activity and unique fluorescence property, as well as specific combining capacity for Cu 2+ to quench its fluorescence. The quenched fluorescence of IRMOF-3-L/Cu 2+ could be recovered by Glyp to realize fluorescence detection of Glyp. Besides, the peroxidase activity of IRMOF-3-L/Cu 2+ could also be inhibited by Glyp, and result in the decrease of catalysate oxTMB, concurrently reducing the changes of colorimetric and SERS signal. Therefore, the fluorescent/colorimetric/SERS triple-mode based detection of Glyp was favorably realized, and the detection limits were calculated as low as 0.738, 2.26 and 0.186 nM, respectively. Furthermore, a portable test strips-smartphone sensing platform was constructed for point of care testing of Glyp in food samples.
研究领域:
分析化学
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食品安全
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DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2023
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IF 6.8
Dongxia Liang,Yinshi Li,Shuoyu Li,Dele Meng,Fengchun Li,Siying Huang,Maojian Gong,Junhao Qin,Huashou Li
Glyphosate (GLY) is the most widely used herbicide worldwide, and its effects on animals and plants have attracted increasing attention. In this study, we explored the following: (1) the effects of multigenerational chronic exposure to GLY and H 2 O 2, alone or in combination, on the egg hatching rate and individual morphology of Pomacea canaliculata ; and (2) the effects of short-term chronic exposure to GLY and H 2 O 2 , alone or in combination, on the reproductive system of P. canaliculata . The results showed that H 2 O 2 and GLY exposure had distinct inhibitory effects on the hatching rate and individual growth indices with a substantial dose effect, and the F1 generation had the lowest resistance. In addition, with the prolongation of exposure time, the ovarian tissue was damaged, and the fecundity decreased; however, the snails could still lay eggs. In conclusion, these results suggest that P. canaliculata can tolerate low concentrations of pollution and in addition to drug dosage, the control should focus on two time points, the juvenile and early stage of spawning.
研究领域:
环境毒理学
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水生生物学
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生态毒理学
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产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
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2023
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IF 9.8
Biao Yan,Yumiao Sun,Kaiyu Fu,Yindan Zhang,Lei Lei,Jun Men,Yongyong Guo,Shengmin Wu,Jian Han,Bingsheng Zhou
Glyphosate, one of the most widely used herbicide worldwide, is potentially harmful to non-target aquatic organisms. However, the environmental health risks regarding impacts on metabolism homeostasis and underlying mechanisms remain unclear. Here we investigated bioaccumulation, metabolism disorders and mechanisms in grass carp after exposure to glyphosate. Higher accumulation of glyphosate and its major metabolite, aminomethylphosphonic acid, in the gut was detected. Intestinal inflammation, barrier damage and hepatic steatosis were caused by glyphosate exposure. Lipid metabolism disorder was confirmed by the decreased triglyceride, increased total cholesterol and lipoproteins in serum and decreased visceral fat. Metabolomics analysis found that glyphosate exposure significantly inhibited bile acids biosynthesis in liver with decreased total bile acids content, which was further supported by significant downregulations of cyp27a1 , cyp8b1 and fxr . Moreover, the dysbiosis of gut microbiota contributed to the inflammation in liver and gut by increasing lipopolysaccharide, as well as to the declined bile acids circulation by reducing secondary bile acids. These results indicated that exposure to environmental levels of glyphosate generated higher bioaccumulation in gut, where evoked enterohepatic injury, intestinal microbiota dysbiosis and disturbed homeostasis of bile acids metabolism; then the functional dysregulation of the gut-liver axis possibly resulted in ultimate lipid metabolism disorder. These findings highlight the metabolism health risks of glyphosate exposure to fish in aquatic environment.
研究领域:
环境科学
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毒理学
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水生生物学
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代谢学
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产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL POLLUTION
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2024
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IF 7.6
Ruihan Xiong,Caixiang Zhang,Hanxiang Xiong,Shuxin Huang,Jiasen Li
Glyphosate as an effective broad-spectrum herbicide is frequently detected in various water and soil resources. Given the ubiquity of β-MnO 2 and δ-MnO 2 colloids in groundwater and soil, the abiotic removal of glyphosate by MnO 2 colloids was investigated. β-MnO 2 colloids exhibited superior glyphosate removal efficiency, up to 37%, compared to 21% for δ-MnO 2 colloids at a pH of 4.0. Glyphosate removal involved simultaneous adsorption and oxidation process , identified by HRTEM , NH 3 -TPD, XPS , LC-MS, FTIR analyses and the occurrence of aminomethylphosphonic acid (AMPA) and Mn 2+ . Moreover, adsorption dominated the removal of glyphosate by two MnO 2 colloids. The solution pH had a substantial effect on glyphosate removal. Co-existing ions in the solution, such as carbonate (CO 3 2− ), phosphate (Na 2 HPO 4 , NaH 2 PO 4 ) and humic acid (HA), were also found to impede glyphosate removal. Phosphate, in particular, exhibited a strong competitive effect for adsorption sites on both MnO 2 colloids. Of them, the removal of glyphosate by β-MnO 2 colloids was more prone to occur due to its higher specific surface area , abundant oxygen vacancies , and moderate acid sites. However, δ-MnO 2 colloids presented a stronger oxidation capacity than that of β-MnO 2 colloids due to the quicker generation rate of Mn 2+ . Finally, AMPA was the same products by two MnO 2 colloids in the oxidation process, revealing the degradation pathway based on the cleavage of C–N bond. Therefore, by comparing kinetics and mechanisms of glyphosate removal by β- and δ-MnO 2 colloids, this study improves us better understanding for the behavior of glyphosate in the environment.
研究领域:
环境科学
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化学
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DOI
PubMed
高影响因子
ANALYST
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2021
·Vol. 146
·期 14
·4595-4604
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IF 4.616
Jiarui Yu,Jingyu Lin,Jianping Li
A new photoelectrochemical enzyme biosensor based on an extended-gate field-effect transistor (EGFET) was constructed for the highly sensitive detection of glyphosate based on the inhibition of acetylcholinesterase (AChE) activity by glyphosate. First, a two-step hydrothermal method was used to introduce ZnO and CdS onto an activated indium tin oxide (ITO) electrode to prepare a CdS/ZnO/ITO electrode. Then, AChE was immobilized on CdS/ZnO/ITO with chitosan to obtain an AChE/CdS/ZnO EGFET sensor. Under optimal experimental conditions, the logarithmic value of glyphosate in the range of 1.0 × 10−15–1.0 × 10−11 mol L−1 exhibited a good linear relationship with the photo-drain current response. The detection limit was 3.8 × 10−16 mol L−1 (signal-to-noise ratio = 3). The results show that the AChE/CdS/ZnO EGFET sensor has extremely high sensitivity and good selectivity. Moreover, the sensor was used for the determination of glyphosate in vegetables, demonstrating its application for the real-time detection of samples.
研究领域:
分析化学
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生物传感器
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环境科学
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电化学
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DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
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2024
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IF 8.2
Hao Sun,Zhazheng He,Yao Gao,Yanhan Yang,Yachang Wang,Aihua Gu,Jin Xu,Yingyi Quan,Yang Yang
The early stage of heart development is highly susceptible to various environmental factors. While the use of animal models has aided in identifying numerous environmental risk factors, the variability between species and the low throughput limit their translational potential. Recently, a type of self-assembling cardiac structures, known as human heart organoids (hHOs), exhibits a remarkable biological consistency with human heart. However, the feasibility of hHOs for assessing cardiac developmental risk factors remains unexplored. Here, we focused on the cardiac developmental effects of core components of Glyphosate-based herbicides (GBHs), the most widely used herbicides, to evaluate the reliability of hHOs for the prediction of possible cardiogenesis toxicity. GBHs have been proven toxic to cardiac development based on multiple animal models, with the mechanism remaining unknown. We found that polyoxyethylene tallow amine (POEA), the most common surfactant in GBHs formulations, played a dominant role in GBHs' heart developmental toxicity. Though there were a few differences in transcriptive features, hHOs exposed to sole POEA and combined POEA and Glyphosate would suffer from both disruption of heart contraction and disturbance of commitment in cardiomyocyte isoforms. By contrast, Glyphosate only caused mild epicardial hyperplasia. This study not only sheds light on the toxic mechanism of GBHs, but also serves as a methodological demonstration, showcasing its effectiveness in recognizing and evaluating environmental risk factors, and deciphering toxic mechanisms.
研究领域:
毒理学
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干细胞生物学
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心脏病学
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环境科学
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Rui Xu,Qin Wei,Dan Li
A self-powered PEC sensor was developed for sensitivity glyphosate detection. • Cs 3 BiBr 6 -AgInS 2 was used as photoanode to provide photo electrons transmission. • CuBi 2 O 4 used as photocathode for providing electric energy for target detection. • The proposed glyphosate sensor showed a wide linear range of 1 × 10 −10 - 5 × 10 −4 mol/L. A self-powered photoelectrochemical (PEC) sensor was developed for the ultrasensitive and rapid detection of glyphosate, a widely used herbicide and potential contaminant in fruits and vegetables. The sensor integrates a Cs 3 BiBr 6 /AgInS 2 composite photoanode with a CuBi 2 O 4 -based photocathode. As a lead-free halide perovskite, Cs 3 BiBr 6 exhibits broad light absorption and prolonged carrier lifetime, while AgInS 2 modification markedly enhances the photoelectric conversion efficiency and optical stability of the photoanode. Meanwhile, CuBi 2 O 4 possesses excellent biocompatibility and abundant active sites, enabling efficient aptamer immobilization for the selective recognition of glyphosate. Under optimized conditions, the photocurrent response decreased linearly with increasing glyphosate concentrations over the range of 1.0 × 10 −10 –5.0 × 10 −4 mol/L, with a low limit of detection (LOD) of 4.6 × 10 −11 mol/L. In addition, the proposed PEC sensor demonstrated excellent stability, reproducibility, and accuracy in the analysis of real food samples, including soybean and corn, highlighting its considerable potential as a reliable analytical platform for on-site monitoring of pesticide residues in agricultural products. Download: Download high-res image (144KB) Download: Download full-size image
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高影响因子
Journal of Environmental Chemical Engineering
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2026
·Vol. 14
·期 3
·122410
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IF 7.5
Jun Wan,Zhaozhe Zhan,Xinchi Wang,Tingyang Li,Yan Wu,Zhiyong Yan
The effective degradation of persistent and potentially toxic glyphosate in water remains a challenge. Herein, we report an engineering strategy of chloride-modulated synthesis to fabricate illite-modified CuFe₂O₄ composite (CuFe₂O₄/Illite) as robust heterogeneous Fenton-like catalysts. The optimized catalyst exhibited outstanding glyphosate removal efficiency (98.6% in 60 min), wide pH adaptability (pH 3–11), and excellent stability (87.85% efficiency after four cycles). Chloride ions were found to slightly promote degradation, whereas common anions like HCO₃ - , NO₃ - , and SO₄² - showed mild inhibition. Quenching experiments and electron paramagnetic resonance (EPR) analysis identified •OH and O₂• - as the primary reactive oxygen species, with a minor contribution from ¹O₂ contribution. X-ray photoelectron spectroscopy (XPS) results revealed that the facilitated Cu²⁺/Cu⁺ and Fe³ ⁺/Fe²⁺ redox cycles served as an efficient electron-transfer highway, dramatically enhancing the heterolytic cleavage of H 2 O 2 and the sustained generation of reactive species. Based on liquid chromatography-mass spectrometry (LC-MS) analysis, a degradation pathway involving C-P bond cleavage and side-chain oxidation was proposed, leading to the mineralization of toxic intermediate Aminomethylphosphonic acid (AMPA) into CO₂, NH₄⁺, and PO₄³ - . This work provides a promising catalyst and elucidates the underlying mechanism for glyphosate wastewater remediation.
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Yijun Mo,Liwen Fan,Chao Wang,Xiaoli Sun,Ziyi Guo,Shengran Yu,Wei Wang,Shi-Wen Lv,Yanqing Cong
The introduction of sulfur endows Fe 2 O 3 with superior catalytic activity. • Sulfur doping regulates Fe spin state to accelerate interfacial electron transfer. • The formation of Fe S bonds triggers abundant oxygen vacancies. • The S-Fe 2 O 3 /PMS system achieves efficient glyphosate degradation dominated by 1 O 2 . Glyphosate residues in aquatic ecosystems pose serious threats to ecological safety and public health owing to their strong biological recalcitrance and intrinsic toxic properties. Herein, sulfur-doped Fe 2 O 3 (designated S-Fe 2 O 3 ) is synthesized via a facile sulfur annealing strategy to tune the electronic configuration of Fe sites and enhance its catalytic activity toward peroxymonosulfate (PMS) activation. Comprehensive characterizations confirm the successful formation of Fe S bonds, abundant oxygen vacancies, and an increased fraction of surface Fe 2+ after sulfur modification. More importantly, sulfur incorporation regulates the spin state of Fe active sites and lowers the work function of Fe 2 O 3 , which accelerates interfacial charge transfer. In addition, the generated Fe S bonds shift the Fe d-band center upward, further elevating the PMS activation capability of S-Fe 2 O 3 . Benefiting from the optimized electronic structure, the S-Fe 2 O 3 /PMS system realizes 94.6% glyphosate elimination within 14 min, with its reaction rate constant 7.8 times larger than that of bare Fe 2 O 3 . Meanwhile, S-Fe 2 O 3 exhibits excellent pH adaptability and prominent anti-interference performance against coexisting inorganic anions. Radical trapping and EPR tests further validate that 1 O 2 serves as the major contributor for glyphosate degradation, while both SO 4 •– and •OH also contribute to pollutant removal. Collectively, this work offers a facile modification route for iron-based catalysts and provides a promising strategy for remediating glyphosate-contaminated wastewater. Download: Download high-res image (252KB) Download: Download full-size image
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DOI
高影响因子
ANALYTICA CHIMICA ACTA
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2026
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IF 6.1
Shuqi Wang,Shuzhen Zheng,Hongzhi Lu,Changsheng Wang,Shoufang Xu
Background Glyphosate (GLY) residues are difficult to remove from agricultural products and pose potential risks to food safety, making their sensitive detection highly desirable. In this study, a Cu 2+ -mediated ratiometric fluorescence sensing platform was constructed for the sensitive detection of GLY by physically mixing polydopamine-polyethyleneimine copolymer dots (PDA-PEI CPDs) with terephthalic acid (PTA) based on a competitive coordination strategy. Results Cu 2+ coordinated with the amino groups on the surface of CPDs and the carboxyl groups of PTA to form a CPDs-PTA-Cu 2+ complex. This process quenched the green fluorescence of CPDs at 530 nm while generating a new blue emission at 450 nm. Upon the addition of GLY, competitive coordination between GLY and Cu 2+ disrupted the complex, resulting in fluorescence recovery at 530 nm and fluorescence quenching at 450 nm, thereby producing a ratiometric fluorescence response. The sensor shows linear ranges of 0-80 μg/mL for GLY (LOD = 5.73 ng/mL). To meet the requirements of on-site applications, a CPDs-Cu 2+ @sodium alginate hydrogel was further prepared. Under 365 nm excitation, the hydrogel responded to GLY through single-emission fluorescence recovery at 530 nm. The hydrogel enabled smartphone-assisted RGB quantitative analysis and in situ semi-quantitative screening of GLY on vegetable surfaces using a wearable hydrogel patch. Significance By integrating solution-phase ratiometric fluorescence quantification with hydrogel-based visual readout, a simple and portable sensing platform was established for accurate GLY determination and visual screening of surface residues.
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DOI
高影响因子
MICROCHEMICAL JOURNAL
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2025
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IF 5.1
Hao Su,Si-qi Yang,Qiu-ling Zhang,Wei-peng Qiu,Lin Luo,Ya-li Zhao,Zhen-lin Xu,Hong Wang,Peng Wen
Considering the hazards of glyphosate and the limitations of current detection methods, a method for rapid detection of glyphosate is designated. Herein, a novel sensing platform based on the immobilization of ratiometric fluorescent probe NH 2 -MIL-101(Fe)@[Ru(bpy) 3 ] 2+ (briefly as MOF@Ru) into agarose hydrogel was fabricated for the rapid and selective detection of glyphosate. Firstly, MOF@Ru with an octahedral morphology was synthesized, and the chemical structure composition was further characterized by X-ray diffraction (XRD), fourier transform infrared spectrometer (FTIR) and X-ray photoelectron spectroscopy (XPS). After that, the ratiometric fluorescence probe was assembled, and the optimized conditions were investigated. Under the optimal detection conditions, the ratiometric fluorescent probe enabled rapid detection (within <2 s), demonstrating a linear response within the concentration range of 0–100 μM (R 2 = 0.9934), and the detection limit was determined to be 0.63 μM. In the spiked recovery experiments with food samples, the recovery rates ranged from 98.90 % to 112.52 %, with a relative standard deviation of less than 6.86 %. Moreover, the fabricated ratiometric fluorescent probe was immobilized into agarose hydrogel, forming a portable test kit, which was compatible with smartphone RGB analysis. The R/B ratio exhibited a concentration-dependent behavior (R 2 = 0.9980), enabling the on-site detection with a detection limit of 0.78 μM, suggesting the potential for the rapid and on-site detection of glyphosate.
研究领域:
环境监测
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分析化学
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材料科学
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食品安全
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传感器与生物传感器
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）