SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Xinxin Zhu,Liting Wang,Joe R. Zhao,Shoujuan Wang,Magdi E. Gibril,Fangong Kong
The rising contamination of water resources by levofloxacin (LEV) requires advanced remediation strategies that exceed the capabilities of the conventional methods. This study reports the rational design of a novel, multi-functional cellulose-phytic acid/Fe-MoS 2 (cellulose-PA/Fe-MoS 2 ) hybrid composite for the highly efficient removal of LEV via synergistic adsorption and photocatalysis. Cellulose served as sustainable substrate and phytic acid acted as a natural cross-linker to enhance the integration and distribution of Fe-MoS 2 onto cellulose substrate. This designed architecture results in enhanced hydrophilicity, minimized MoS 2 aggregation, and a maximized density of active sites, as confirmed by comprehensive characterization (SEM, XRD, FTIR, XPS, BET, LC-MS, EPR). The prepared composite demonstrated exceptional, temperature-dependent LEV adsorption capacities of up to 210.97 mg/g (95%) within 40 min, with kinetics and isotherms best described by pseudo-second-order and Langmuir models, indicative of chemisorption. The adsorption mechanism driven by a combination of electrostatic attraction, π–π stacking, hydrogen bonding, and coordination complexation, resulting in effective removal across a broad pH range (3−10). The cellulose-PA/Fe-MoS 2 exhibited photocatalytic effect, achieving efficient degradation of levofloxacin (LEV) (98.5%) within short time (15 mins) into small molecules (CO 2 , H 2 O, NH 3 , NO 3 , F, …etc.) as confirmed with LC-MS, driven primarily by reactive species (•O 2 − , •OH, h + ). In addition, it was demonstrated good recyclability, maintaining high performance over five consecutive cycles. These findings suggest that the designed cellulose-PA/Fe-MoS 2 composite could be used as a green and sustainable multifunctional material to simultaneously remove and degrade antibiotics from water environments.
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CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Tao Wang,Xinping He,Ye Li,Jiding Li
A novel aromatic poly ( m -phenylene isophthalamide) (PMIA) hollow fiber substrate was first introduced to poly(piperazine-amide) (PA) composite membrane for nanofiltration. Chemical composition, morphological structure and top surface property were comprehensively characterized. Analyses indicated that a negative charged polyamide selective layer was successfully synthesized on PMIA substrate via interfacial polymerization. For nanofiltration tests, the as-prepared PA/PMIA hollow fiber membrane exhibited not only a superior permeation (104.13 ± 0.70 L·m −2 ·h −1 , 0.6 MPa), but also an excellent salt rejection in the order as: R N a 2 S O 4 (98.45%) > R MgS O 4 (97.98%) > R CaC l 2 (96.02%) > R MgC l 2 (95.74%) > R NaCl (54.07%). Additionally, nanofiltration performance was evaluated with three kinds of anionic dyes (Chromotrope FB, Reactive Yellow 3, Direct Fast Blue B2RL) in varied conditions, including operating pressure, dye content, pH environment and salty co-exist. Evidence supported that an outstanding dye-removal ability was achieved using the developed PA/PMIA membrane, which was specifically higher than 97%. Integrate all the findings, this work provided a new PMIA based hollow fiber nanofiltration membrane, which should be promising in application of dye wastewater treatment.
研究领域:
材料科学
·
环境工程
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
·
IF 4.4
Xun Zhou,Juerui Zhang,Dongyan Huang,Yinhui Yi,Kechen Wu,Gangbing Zhu
In this work, a ratiometric fluorescence sensing platform was established to detect Cu 2+ and D-PA ( d -penicillamine) based on nitrogen-doped Ti 3 C 2 MXene quantum dots ( N -MODs) that was prepared via a simple hydrothermal method and exhibited strong fluorescent and photoluminescence performance as well as excellent stability. Since the oxidation reaction between o -phenylenediamine (OPD) and Cu 2+ induced the formation of 2,3-diaminophenazine (ox-OPD) which not only can emerge an emission peak at 570 nm, but also inhibit the fluorescence intensity of N -MQDs at 450 nm, a ratiometric reverse fluorescence sensor via fluorescence resonance energy transfer (FRET) was designed to sensitively detect Cu 2+ , where N -MQDs acted as energy donor and ox-OPD as energy acceptor. More importantly, another considerably interesting phenomenon was that their catalytic oxidation reaction can be restrained in the presence of D-PA because of the coordination of Cu 2+ with D-PA, further triggering the obvious changes in ratio fluorescent signal and color, thus a ratiometric fluorescent sensor of determining D-PA was proposed also in this work. After optimizing various conditions, the ratiometric sensing platform showed rather low detection limits for Cu 2+ (3.0 nM) and D-PA (0.115 μM), coupled with excellent sensitivity and stability.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Bingbing Yuan,Shuang Yuan,Chaozheng Jia,Ping Hu,Siheng Zhao,Xiaozhuan Zhang,Zewen Xu,Lihong Liu,Meng You,Shengchao Zhao,Kuo Chen,Dongxiao Yang,Juhui Jiang,Xiangdong Lou,Jianxun Dong,Tatiana V. Plisko,Q.Jason Niu
To address the growing global challenge of water scarcity, developing high-performance reverse osmosis (RO) membranes for desalination and water purification is essential. However, conventional polyamide (PA) thin-film composite (TFC) membranes are limited by the trade-off between permeability and selectivity, as well as limited rejection of small-molecular contaminants. In this study, we report a novel high-permeability thin-film nanocomposite (TFN) RO membrane by tuning the hydrophilicity of a zeolitic imidazolate framework-8 (ZIF-8) interlayer to achieve synergistic enhancement in both desalination and micropollutant removal. Specifically, a ZIF-8 interlayer was in situ grown on a hyperbranched PA-UIO-66-NH 2 support, followed by partial ligand exchange with 5,6-dimethylbenzimidazole (Hdmbim) to reduce its hydrophilicity. This modification facilitated the diffusion of m-phenylenediamine (MPD) monomers, enabling the formation of a highly cross-linked PA selective layer (h-TFN) with angstrom-scale water transport channels. The optimized h-TFN membrane exhibited a water permeability of 5.40 L·m −2 ·h −1 ·bar −1 , 2.94 times that of the control TFC membrane, while maintaining high NaCl rejection (98.35 %). Moreover, it achieved 96.06 ± 0.18 % rejection for micropollutants such as heptyl paraben (HP). These results surpass the permeability–selectivity limitations of existing membranes and demonstrate a promising strategy for the design of advanced RO membranes capable of efficient desalination and micropollutant removal.
研究领域:
水处理
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膜技术
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纳米技术
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海水淡化
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环境工程
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SURFACE & COATINGS TECHNOLOGY
·
2021
·
IF 4.158
Wentai Zhang,Sheng Zhao,Xiaoshan Mo,Peng Xian,Shuai Tang,Junyu Qian,Gang Shen,Chao Zhou,Nan Huang,Haijun Zhang,Guojiang Wan
In this study, Mg ions incorporated phytic acid (PA) and zoledronic acid (ZA) of metal-organic complex coating was built on Mg substrate. This coating aims to fulfill the corrosion controlling and differential regulation on osteoblast vs. osteoclast responses simultaneously. PA and ZA molecules were co-immobilized on the alkaline pretreated Mg by a facile one-step dip-coating method. Such immobilization process was executed by the chelation reaction between PA/ZA molecules and in-situ released Mg ions. This coating showed a homogeneous structure with metal-organic like framework. The electrochemical corrosion resistance and long-term degradation behavior of coated samples were remarkably improved. Consequently, the well-controlled Mg ion release, as well as the osteo-compatible PA molecule, promoted the proliferation of pre-osteoblast cells (MC3T3-E1). Moreover, this coating significantly suppressed both the proliferation and differentiation of osteoclast cells owing to the nature of ZA. This metal-organic complex coating offers a promising modifying strategy for Mg-based orthopedic implants for osteoporotic fracture healing.
研究领域:
材料科学
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生物材料
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骨科
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生物医学工程
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Irfan Ijaz,Aysha Bukhari,Ammara Nazir,Ezaz Gilani,Hina Zain,Attia Shaheen,Mohammed Rafi Shaik,Mujeeb Khan
Designing effective adsorbents for adsorption of the threatening level of pharmaceuticals and personal care products (PPCPs) pollution is an immediate challenge for wastewater treatment. In the current work, molybdenum borides (MoBT x ) were first composited with silk fibroin (SF) through ultrasonic self-assembly. Then, the MoBT x @SF composite’s surface was modified with phytic acid (PA) to create MoBT x @SF@PA composite. The as-synthesized MoBT x @SF@PA adsorbent was developed to effectively remove indomethacin (IDM) and ceftriaxone (CEF). Due to the abundance of functional groups, highly exposed available active sites, and higher BET (Brunauer-Emmett-Teller) surface area (786.8 m 2 /g), MoBT x @SF@PA demonstrated an outstanding adsorption capability for IDM (549.89 mg/g) and CEF (959.18 mg/g), exceeding the earlier reported adsorbents. A kinetic study revealed that the interaction between the MoBT x @SF@PA adsorbent and PPCPs obeyed a pseudo-second-order model (PSO), implying that chemisorption controls the adsorption process. The Langmuir isotherm model and thermodynamic study indicated that IDM and CEF adsorption followed monolayer adsorption and were endothermic and spontaneous. Fourier-transformed infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) were used to explore the adsorption mechanism. Multiple hydrogen bindings, electrostatic interactions, high surface area, and porosity of the composite were primarily responsible for remarkable adsorption capacity. These results highlight a versatile approach for MoBT x -based adsorbent preparation with exceptional adsorption qualities appropriate for real-world PPCPc-polluted wastewater treatment.
研究领域:
环境科学
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材料科学
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药学
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Xiaochun Zheng,Weiwei Kang,Yarong Jin,Xin Zhang,Wenxuan Wang,Dongsheng Li,Shutong Wu,Lin Chen,Shichao Meng,Rong Dai,Ziliang Zheng,Ruiping Zhang
Rheumatoid arthritis (RA) is currently one of the most common systemic autoimmune disorders, with no clinically effective theranostics. Therapeutic manipulation of the gasotransmitter hydrogen sulfide (H 2 S) has exhibited promising potential as an innovative strategy in RA, whereas limited with non-targeting, low solubility, and systemic toxicity. In this work, based on the physicochemical and structural advantages of stimulus-responsive nanotechnology, we develop multifunctional glutathione (GSH)-responsive H 2 S nanogenerators (BDMA NGs), achieving activatable precise second near-infrared fluorescence (NIR-II FL)/photoacoustic (PA) bimodal imaging-guided gas/chemotherapy synergistic therapy. Contributed to the suitable size and excellent biocompatibility, the BDMA NGs accumulate passively in the RA region and then feature a responsive deformation reaction with GSH to release functional small molecules: H 2 S and methotrexate (MTX). The H 2 S undergoes a mineralization process with Ag + ions in situ, resulting in the rapid formation of Ag 2 S to “turn on” the NIR-II FL/PA signals. Remarkably, the effective generation of H 2 S downregulates hypoxia-inducible factor-1 α (HIF-1 α ) and promotes nuclear factor erythroid 2-related factor 2 (Nrf2) nuclear translocation, thereby restoring homeostasis in the RA microenvironment and facilitating the reprogramming of pro-inflammatory macrophages (M1) into anti-inflammatory phenotype (M2). Moreover, the controlled release of MTX, clinically approved drug for RA, synergistically promotes repolarization to further suppress local inflammation. Overall, the H 2 S-based nanogenerators BDMA NGs present a sophisticated and versatile strategy for implementing stimuli-responsive imaging and M1-to-M2 repolarization, demonstrating significant potential in the theranostics of RA and clinical transformation.
研究领域:
纳米技术
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成像
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诊疗学
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自身免疫性疾病
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药理学
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Journal of Materials Chemistry B
·
2023
·
IF 7
Qi Long,Yuliang Yang,Fangling Liao,Haoting Chen,Dongyue He,Shengliang Li,Li Pengcheng,Weisheng Guo,Yafang Xiao
Photothermal immunotherapy has shown great potential for efficient cancer treatment. However, the immunosuppressive tumor microenvironment forms a heavy barrier for photothermal-induced anti-tumor immunity by inhibiting dendritic cells (DCs) maturation and cytotoxic T cell response. Moreover, the lack of reliable spatiotemporal imaging modalities makes photothermal immunotherapy difficult to guide tumor ablation and monitor the therapeutic outcomes in real time. Herein, we designed a theranostic thermosensitive liposome (PLDD) as a versatile nanoplatform to boost adaptive anti-tumor immunity of photothermal immunotherapy and achieve multiple bioimaging modalities in a real-time manner. The PLDD contains two major functional components: a multifunctional photothermal agent (DTTB) and an immune potentiator STING pathway agonist (DMXAA). Upon irradiation, the heat generated by DTTB induced the immunogenic cell death (ICD) of the tumor and dissociated the structure of thermosensitive liposome to release DMXAA, which ultimately activated the STING pathway and promoted the ICD-induced immune response by increasing DC cells maturation and T cell recruitment. Meanwhile, the DTTB in PLDD displayed excellent second near-infrared (NIR-II) fluorescence and photoacoustic (PA) dual-modal imaging, which provided omnibearing information on the tumor and guided the subsequent therapeutic operation. Therefore, this versatile PLDD with light-triggered promotion of anti-tumor immunity and multiple spatiotemporal imaging profiles holds great potential for the future development of cancer immunotherapy.
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高影响因子
CHEMISTRY & BIODIVERSITY
·
2023
·Vol. 20
·期 8
·e202300831
·
IF 2.9
Fengyun Chen,Ansar Javeed,Qiuyu Zeng,Quan Zhang,Bingnan Han
Bacterial infected environments and resulting bacterial infections have been threatening the human health globally. Due to increased bacterial resistance caused by improper and excessive use of antibiotics, antibacterial biomaterials are being developed as alternatives to antibiotics in some cases. Herein, an advanced multifunctional hydrogel with excellent antibacterial properties, enhanced mechanical properties, biocompatibility and self-healing performance, was designed through freezing-thawing method. This hydrogel network is composed of polyvinyl alcohol (PVA), carboxymethyl chitosan (CMCS), protocatechualdehyde (PA), ferric iron (Fe) and an antimicrobial cyclic peptide actinomycin X2 (Ac.X2). The double dynamic bonds among protocatechualdehyde (PA), ferric iron (Fe) and carboxymethyl chitosan containing coordinate bond (catechol-Fe) as well as dynamic Schiff base bonds and hydrogen bonds endowed the hydrogel with enhanced mechanical properties. Successful formation of hydrogel was confirmed through ATR-IR and XRD, and structural evaluation through SEM analysis, whereas mechanical properties were tested with electromechanical universal testing machine. The resulting PVA/CMCS/Ac.X2/PA@Fe (PCXPA) hydrogel has favorable biocompatibility and excellent broad-spectrum antimicrobial activity against both S. aureus (95.3 %) and E. coli (90.2 %) compared with free-soluble Ac.X2, which exhibited subpar performance against E. coli reported in our previous studies. This work provides a new insight on preparing multifunctional hydrogels containing antimicrobial peptides as antibacterial material. Graphical
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APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Ruxia Song,Shihong Zhang,Yi He,Bo Liu,Hongjie Li,Zhifei Zhang,Yahui He
In this study, a novel Ni-Cu/OH-BN(h)-PA-Zn-DCD composite coatings with excellent wear resistance and corrosion resistance was developed, which may be used in the field of seawater corrosion. By the self-assembling of phytic acid, Zn 2+ and dicyandiamide to grow PA-Zn-DCD structure onto the surface of hydroxylated BN(h) nanosheets, obtained a hybrid denoted as OH-BN(h)-PA-Zn-DCD, which was doped into Ni-Cu coating by pulse electrodeposition. The results show that OH-BN(h) and OH-BN(h)-PA-Zn-DCD hybrids affect the surface morphology, roughness, microcrystals size and thickness of the composite coatings. Simultaneously, compared with NC coating and NC/HB-1.5 coating, NC/BP-1.5 coating has the highest microhardness (559.26 Hv), the lowest friction coefficient (0.172), and the best corrosion resistance (i corr is 3.551 × 10 −8 A·cm −2 , R ct is 1.098 × 10 6 Ω·cm 2 ). In addition, the EIS results of the immersed specimens showed that the NC/BP-1.5 composite coating still has good protective ability after soaking for 15 days in simulated seawater medium (R ct is 7.434 × 10 6 Ω·cm 2 ).
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DESALINATION
·
2022
·
IF 11.211
Xiumin Zhang,Yongping Dong,Qingyi Wang,Hang Yu,Congjie Gao,Lixin Xue
Structures and NF performance of TFC-Co and TFC membranes activated with 50 % alcohol solutions were studied. Methanol and glycol solution activation increased water flux 2–4 times without trading off salt rejection while glycerin solution activation increased water flux 3–4 times with reduced salt rejection and increased dye/salt retention selectivity . The Stokes radius of TFC-Co membrane changed from 0.77 nm to 0.66, 0.78 and 0.92 nm while the TFC membrane changed from 0.54 nm to 0.55, 0.65 and 0.70 nm after activation with methanol, glycol and glycerin solutions, respectively. Capillary pore filling models were developed from pure alcohol absorption experiments including the stages of initial pore filling, pore expansion, pore relaxation and pore adjustment, while most Stokes radius after 50 % solutions activation were found to be close to the relaxed pore radius values (r rx ) or half of the expanded pore radius values (r ex ) from pure alcohol absorption experiments.
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JOURNAL OF MEMBRANE SCIENCE
·
2022
·
IF 10.53
Xian Chang,Zixuan Lv,Hang Yu,Shiyang Li,Guojun Jiang,Congjie Gao,Lixin Xue
Thin Film Composite Polyamide (TFC-PA) Total Heat Exchange Membranes (THEMs) with ultrahigh sensible heat exchange efficiency, high enthalpy exchange efficiency, high CO 2 gas barrier property were successfully prepared by interfacial polymerization between m-phenylenediamine (MPD) and trimesoyl chloride (TMC). The performances of formed THEMs could be greatly impacted by their surface roughness , thickness, surface hydrophilicity, cross-linking degree and counter-ions retention controlled by the MPD concentration, TMC concentration, reaction time and post treatment procedures. Their H 2 O permeation coefficient could be improved by increasing the surface hydrophilicity and decreasing cross-linking degrees of the formed polyamide layers while their CO 2 barrier property could be improved by retaining more counter ions in PA layers. THEMs with ultrahigh sensible heat exchange efficiency of 95%+, high enthalpy exchange efficiency of 60%–65%, greatly improved CO 2 barrier property and superior mechanical strengths could be obtained for potential applications in ERV systems.
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