BIOSENSORS & BIOELECTRONICS
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2016
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IF 7.476
Guixiang Wang,Rui Han,Xiaoli Su,Yinan Li,Guiyun Xu,Xiliang Luo
Zwitterionic peptides were anchored to a conducting polymer of citrate doped poly(3,4-ethylenedioxythiophene) (PEDOT) via the nickel cation coordination, and the obtained peptide modified PEDOT, with excellent antifouling ability and good conductivity , was further used for the immobilization of a DNA probe to construct an electrochemical biosensor for the breast cancer marker BRCA1 . The DNA biosensor was highly sensitive (with detection limit of 0.03 fM) and selective, and it was able to detect BRCA1 in 5% (v/v) human plasma with satisfying accuracy and low fouling. The marriage of antifouling and biocompatible peptides with conducting polymers opened a new avenue to construct electrochemical biosensors capable of assaying targets in complex biological media with high sensitivity and without biofouling.
研究领域:
生物传感器
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电化学
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材料科学
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癌症研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanoscale
·
2024
·Vol. 16
·期 16
·8162-8176
·
IF 5.8
Xinmeng Zhang,Mingyue Bai,Lei Ge,Yuanyuan Yao
The slow redox rate of hydrogen peroxide (H2O2) in neutral environments makes the H2O2 sensor inadequate for the detection of low levels of signalling molecules. The aim of this study is to fabricate a flexible sensing electrode by hydrothermally loading micro-nanometer Ni and Co(OH)2 on carbon cloth (CC) and electrochemically depositing poly(3,4-ethylenedioxythiophene) (PEDOT) on the surface of the electrode. The sensor presented high sensitivity (10.43 mA mM−1 cm−2), a wide detection range (0.033–120.848 mM), a low detection limit (0.92 nM), high stability, and excellent anti-interference performance in neutral solutions. Ni–Co(OH)2 provides abundant active sites while CC solves their agglomeration phenomenon and conductivity. The PEDOT film offers heightened conductivity, hydrophilicity, interfacial stability, and an electrochemically active surface area (ECSA). The side area of the chrysanthemum petal like PEDOT is 39 ± 7 times the bottom area, and PEDOT increases the ECSA of the composite to six times that of CC. Electrochemical precise control of PEDOT morphology to improve sensor performance provides a new strategy for the application of PEDOT in sensors.
研究领域:
材料科学
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生物医学工程
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分析化学
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产品关联
DOI
PubMed
高影响因子
BIOELECTROCHEMISTRY
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2020
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IF 4.722
Jiasheng Wang,Dongwei Wang,Ni Hui
The application of polypeptides in bio-interfaces and biosensors is of great interest because polypeptides are biocompatible and easy to design. A novel polymer nanocomposite was prepared by the electropolymerization of the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) with a newly designed polypeptide. The nanocomposite polypeptide doped PEDOT (PEDOT/PEP), with a 3D microporous network structure, large surface area and excellent antifouling ability, was utilized for the attachment of BRCA1 complementary oligonucleotides to construct a DNA biosensor. The fabricated DNA biosensor showed favorable selectivity (with a detection limit of 0.0034 pM) and high sensitivity. The biosensor was also capable of detecting the target DNA (BRCA1) in 1% (V/V) human serum samples. The combination of a conducting polymer PEDOT with an antifouling and biocompatible polypeptide demonstrates a new method for preparing electrochemical sensors, that are capable of detecting targets in complex biological samples without strong nonspecific protein adsorption.
研究领域:
生物传感器
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材料科学
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癌症研究
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电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Lin Huang,Xiaqing Yang,Linglong Deng,Daofa Ying,Ang Lu,Lina Zhang,Aixi Yu,Bo Duan
The nerve guidance conduit (NGC) is a promising clinical strategy for regenerating the critical-sized peripheral nerve injury. In this study, the polysaccharide chitin is used to fabricate the hydrogel film for inducing the impaired sciatic nerve regeneration through incorporating the conductive poly(3,4-ethylenedioxythiophene) nanoparticles (PEDOT NPs) and modifying with cell adhesive tetrapeptide Cys–Arg–Gly–Asp (CRGD) (ChT-PEDOT-p). The partial deacetylation process of chitin for exposing the amino groups is performed to (i) improve the electrostatic interaction between chitin and the negatively charged PEDOT for enhancing the composite hydrogel strength and (ii) offer the active sites for peptide modification. The as-prepared hydrogel remarkably promotes the in vitro RSC-96 cell adhesion and proliferation, as well as the Schwann cell activity-related gene S100, NF-200, and myelin basic protein (MBP) expression. Function of gastrocnemius muscle and thickness of myelinated axon in chitin/PEDOT groups are analogous to the autograft in 10 mm rat sciatic nerve defect. Immunofluorescence, immunohistochemistry, western blotting, and toluidine blue staining analyses on the regenerated sciatic nerve explain that the attachment and proliferation enhancement of Schwann cells and angiogenesis are the vital factors for the chitin/PEDOT composite to facilitate the nerve regeneration. This work provides an applicable chitin-based NGC material for accelerating the peripheral nerve restoration.
研究领域:
生物材料
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神经科学
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组织工程
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再生医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Science and Engineering B-Advanced Functional Solid-State Materials
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2022
·
IF 3.407
Yao Wang,Yuedan Wang,Rufeng Zhu,Yang Tao,Yuanli Chen,Qiongzhen Liu,Xue Liu,Dong Wang
Fiber based organic electrochemical transistors (FECTs) functionalized with poly(3, 4-ethylenedioxythiophene)/multiwalled carbon nanotube channel as transducer have been developed to detect ultralow concentration of potassium ions in the human body. Here, MWCNT increases the specific surface area and reaction sites of the cotton fiber, and induces a uniform and dense conductive network of PEDOT nanowires on the fiber, which greatly improves the performance of FECTs. In addtion, it can still maintain superior transistor performance under different bending degrees. The performance of ion sensors based on FECTs is systematically investigated. K + can be detected in the range of 1–1000 nM with fast response and good reproducibility. Furthermore, the sensor combined with ion selective membrane has excellent anti-interference ability. The practical applicability of the sensor for K + detection in artificial saliva has been verified. The sensors can also be integrated into fabric by hand-weaving, which providing a promising platform for convenient wearable healthcare monitoring.
研究领域:
生物医学工程
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材料科学
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传感器技术
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产品关联
DOI
高影响因子
Inorganic Chemistry Frontiers
·
2023
·Vol. 10
·期 17
·4993-5003
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IF 7
Yuanduo Qu,Siqi Liao,Liangyi Wu,Junkai Wang,Lianfeng Duan,Xia He,Fushen Lu
An integrated photocapacitor (IPC) is a light-driven self-charging capacitor, which can overcome the impact of solar energy fluctuations by converting the solar radiation to electrochemical energy and store it simultaneously. However, current IPCs suffer from incompatibility problems, device packing, serious carrier recombination, and long-range electron transmission path, which lead to low conversion efficiency and cycling performance. To address these issues, we propose a three-electrode quasi-solid-state IPC based on a charge-separated transition mechanism of PEDOT/RGO compatible electrode and BMIMBF4 ion gel electrolyte to accelerate carrier migration. The overall conversion efficiency of this IPC reached 5.8% and the energy storage efficiency could be maintained at 84.57%. Besides that, this bendable free-standing electrode can be applied in flexible and high-voltage IPCs as a reliable off-grid systems to supply next-generation electronics.
研究领域:
材料科学
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能源技术
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产品关联
DOI
高影响因子
CARBON
·
2025
·
IF 11.6
Yajun Wang,Tursun Abdiryim,Ruxangul Jamal,Feng Xu,Qilong Zhang,Yiming Liu
This study presents a flexible UV photodetector with an organic-inorganic hybrid structure, fabricated using advanced face-to-face self-assembly. The detector is composed of PEDOT-CH 2 OH and nitrogen-doped graphene quantum dots (N-GQDs) modified zinc oxide nanoflowers (ZnO NFs). The sulfur and hydroxyl groups in PEDOT-CH 2 OH, along with nitrogen and oxygen functional groups in N-GQDs, promote the formation and stabilization of oxygen vacancies (Vo) on the ZnO NFs surface. This significantly enhances carrier separation efficiency, reduces electron-hole recombination, and improves the detector's performance. Under 365 nm UV light, the device achieves a response rate of 1.31 mA W −1 at 0V bias, with fast rise times (0.078 s) and fall time (0.093 s). The detector shows excellent stability and rapid photonic response, providing solid support for wearable electronics and new theoretical guidance for ZnO photodetector improvements.
研究领域:
材料科学
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光电子学
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Electrochemical Science
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2023
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IF 1.5
Min Yang,Ying Liu,Yonggui Song,Guochun Zhao,Haiyan Tan,Qiuping Zhang,Fugang Xu
In this study, a new approach was developed to prepare a novel three dimensional macroporous poly(3,4-ethylene-dioxythiophene)-Prussian blue hybrid 3D-PEDOT-PB for sensitive H 2 O 2 detection. 3D-PEDOT prepared by electrodeposition not only as a conductive matrix, but also as a reductant to initiate the spontaneously “electroless” deposition of PB and as scaffold with large surface area for firmly anchoring more PB NPs. The 3D macroporous structure of the hybrid also facilitates the electron transfer and mass transport. Due to the synergistic interaction between the 3D-PEDOT and the PB NPs, the hybrid shows remarkably enhanced activity for H 2 O 2 reduction. A non-enzymatic H 2 O 2 sensor with a high sensitivity (981 μA·mM -1 ·cm -2 ), a wide linear range (0.17 μM to 0.257 mM) and a low detection limit (80 nM) was fabricated based on the 3D-PEDOT-PB hybrid. Furthermore, the prepared sensor displays a rapid, stable response and good selectivity. The simple preparation and advanced properties of the novel 3D-PEDOT-PB hybrid may have promising applications in electrochemical sensor, electrochromic device and so on.
研究领域:
材料科学
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分析化学
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电化学
✓ 已验证
DOI
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Jiangping Jing,Zhuoyuan Chen,Chang Feng,Li Ma,Jian Hou,Likun Xu,Mingxian Sun
The application of graphitic carbon nitride (g-C3N4) in the field of photoelectrochemistry is booming due to its visible light response, stability, low cost, and environmental compatibility. However, the modulation of the photogenerated charge carriers in the g-C3N4 photoelectrode is still a challenge, especially for the control of the charge transfer direction and the improvement of charge migration rate. In this work, PEDOT was in situ deposited on the surface of g-C3N4 to modify the transfer process of the photogenerated holes. The band structure was investigated based on the valence band and work function. The charge transfer properties were characterized by analyzing the processes of hole transfer, separation, and depolarization. PEDOT is found to play two roles: one is to act as a semiconductor material to form a heterojunction with g-C3N4, regulating the charge transfer direction and promoting the separation efficiency of the photogenerated charge carriers; the other one is to act as a hole transmission medium, promoting the migration and depolarization processes of the photogenerated holes. Therefore, the photoelectrochemical performance of g-C3N4 is greatly improved, which is further verified by the enhanced photoinduced cathodic protection performance, whether with the assistance of hole sacrificial agents or not.
研究领域:
材料科学
·
光化学
✓ 已验证
DOI
高影响因子
ACS Applied Electronic Materials
·
2025
·
IF 4.7
Pingping Yu,Xiaotian Yu,Yuqing Kong,Lin Sun,Yanfeng Jiang
Self-powered polarization-sensitive photodetectors play an important role in considerable fields such as navigation, military reconnaissance, and medical imaging. In this paper, a Sb2Se3/PEDOT heterojunction was developed by spraying a PEDOT film to a single Sb2Se3 microbelt (MB) with high crystallinity, synthesized using the CVD process. The self-powered Sb2Se3/PEDOT photodetector (PD) exhibits high polarization-sensitive and broadband detection in the visible–near-infrared range (368–1300 nm). The device achieves a high on/off ratio of 1804, maximum responsivity and specific detectivity of 2.33 A W–1 and 3.84 × 1012 Jones, and fast response time (23 ms/60 ms) at 724 nm under zero bias. The Sb2Se3/PEDOT PD exhibits excellent polarization sensitivity characteristics with the highest anisotropy ratio of 1.7 under 724 nm at zero bias, which is 1.13 times higher compared to the Sb2Se3 PD (1.32) at 0.2 V. The enhanced ability to detect polarized light of the Sb2Se3/PEDOT PD can be attributed to inherent anisotropy of the Sb2Se3 MB and good polarization-sensitivity of PEDOT to form a type II heterojunction, which is suitable for fast separation of photogenerated carriers. Excellent imaging capabilities of the letters “JN” and sensitivity to polarized light at 724 nm have been established for the high-resolution single-pixel image sensor at 0 V bias. This work demonstrates an effective strategy for high-optical response, self-powered, polarization-sensitive photodetection, and imaging using Sb2Se3/PEDOT heterojunctions.
研究领域:
材料科学
·
光子学
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电子学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2017
·
IF 6.216
Ziyang Lu,Zehui Yu,Jinbo Dong,Minshan Song,Yang Liu,Xinlin Liu,Zhongfei Ma,Hang Su,Yongsheng Yan,Pengwei Huo
The Z-scheme imprinted ZnFe 2 O 4 /Ag/PEDOT was synthesized by the microwave polymerization method and surface imprinting technique, which possessed good partial hollow spherical structure, good light response ability, good magnetic separation performance, good photocatalytic stability and reproducibility. More importantly, due to the introduction of Ag/PEDOT into the surface imprinted layer, Z-scheme structure was formed to enhance the photocatalytic activity based on Ag acted as the mediator, meanwhile, owing to the existence of the imprinted cavity in the surface imprinted layer, the selectivity had been significantly improved, in a word, the as-prepared Z-scheme imprinted ZnFe 2 O 4 /Ag/PEDOT achieved the goal for simultaneously improving the photocatalytic activity and selectivity. Z-scheme imprinted ZnFe 2 O 4 /Ag/PEDOT possessed the highest photodegradation rate (71.77%) for degradation of tetracycline under the simulated sunlight irradiation of 120 min, which was approximately 4.74 times to that of ZnFe 2 O 4 , 1.42 times to that of Ag/PEDOT and 1.31 times to that of non-imprinted ZnFe 2 O 4 /Ag/PEDOT, respectively. And the coefficient of selectivity of Z-scheme imprinted ZnFe 2 O 4 /Ag/PEDOT relative to ZnFe 2 O 4 , Ag/PEDOT, non-imprinted ZnFe 2 O 4 /Ag/PEDOT was 1.84, 1.82, 1.79 in the single antibiotic solution and 1.78, 1.75, 1.67 in the binary antibiotic solution, respectively. This work provided a new synthesis strategy for the imprinted photocatalysts and also provided a new idea for the treatment of specific pollutants in the water environment.
研究领域:
材料科学
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环境科学
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光催化技术
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2021
·
IF 8.198
Huiying Liu,Ruxangul Jamal,Tursun Abdiryim,Rena Simayi,Lielie Liu,Yajun Liu
In this paper, carboxylated cellulose (CLC) dissolved in [BMIM]Cl as a soft template combined with the functional group (−NH2, −SH)-grafted poly(3,4-ethylene dioxythiophene) (PEDOT) derivatives was synthesized by an in situ polymerization method. Structural analysis revealed that CLC increased the degree of conjugation of the polymers in the composites and also led to the formation of the fibrous and sheet structure of the composite. The results of the electrochemical performance measurements revealed that the electrode modified by PEDOT-MeNH2/CLC and PEDOT-MeSH/CLC had detection limits (S/N = 3) of 0.38(0.1–380 μM) and 0.042(0.02–520 μM) for the detection of guanine (G), while for the detection of uric acid (UA), the corresponding detection limits (S/N = 3) were 0.255(5–400 μM) and 0.085(0.4–650 μM). The PEDOT-MeSH/CLC-based electrochemical sensor also possessed a wide linear response with the detection limits of 0.077(0.6–620 μM) and 0.144(0.2–460 μM) for the simultaneous detection of UA and G, respectively.
研究领域:
材料科学
·
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）