ANALYTICAL CHEMISTRY
·
2017
·
IF 6.32
Zhenli Qiu,Jian Shu,Dianping Tang
Titanium dioxide (TiO2; as a potential photosensitizer) has good photocurrent performance and chemical stability but often exhibits low utilization efficiency under ultraviolet (UV) region excitation. Herein, we devised a near-infrared light-to-UV light-mediated photoelectrochemical (PEC) aptasensing platform for the sensitive detection of carcinoembryonic antigen (CEA) based on core–shell NaYF4:Yb,Tm@TiO2 upconversion microrods by coupling with target-triggered rolling circle amplification (RCA). The upconversion microrods synthesized through the hydrothermal reaction could act as a photosensing platform to convert the near-infrared (near-IR) excitation into UV emission for generation of photoinduced electrons. The target analyte was determined on a functional magnetic bead by using the corresponding aptamers with a sandwich-type assay format. Upon target CEA introduction, a complex was first formed between capture aptamer-1-conjugated magnetic bead (Apt1-MB) and aptamer-2-primer DNA (Apt2-pDNA). Thereafter, the carried primer DNA by the aptamer-2 paired with linear padlock DNA to trigger the RCA reaction. The guanine (G)-rich product by RCA reaction was cleaved by exonuclease I and exonuclease III (Exos I/III), thereby resulting in the formation of numerous individual guanine bases to enhance the photocurrent of core–shell NaYF4:Yb,Tm@TiO2 upconversion microrods under near-IR illumination (980 nm). Under optimal conditions, the near-IR light-mediated PEC aptasensing system could exhibit good photoelectrochemical response toward target CEA and allowed for the detection of target CEA as low as 3.6 pg mL–1. High reproducibility and good accuracy were achieved for analysis of human serum specimens. Importantly, the near-IR-activated PEC aptasensing scheme provides a promising platform for ultrasensitive detection of other biomolecules.
研究领域:
生物医学工程
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分析化学
·
癌症诊断
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产品关联
DOI
PubMed
高影响因子
OPTICAL MATERIALS
·
2023
·
IF 3.9
Xiaoyan Zhao,Yongcheng Zhou,Hua Guo,Yuqi Zhai,Xianrui Zou,Donghui Wang
Titanium dioxide (TiO 2 ) has received widespread attention as high stability, low toxicity and costless photocatalyst , but it only exhibits photocatalytic activity under ultraviolet (UV) light. To improve TiO 2 photocatalytic efficiency, Bio-CaCO 3 /WO 3 /TiO 2 /(Ca,Y)F 2 :Tm,Yb was prepared. TiO 2 was combined with upconversion materials, coupled with WO 3 and loaded on oyster shell powder (Bio-CaCO 3 ), which showed that the prepared photocatalyst effectively reduce the band gap of TiO 2 , expand the photoreaction range of the material and avoid agglomeration, thus improving its photocatalytic efficiency and antibacterial efficiency. The photocatalytic degradation efficiency of Bio-CaCO 3 /WO 3 /TiO 2 /(Ca,Y)F 2 :Tm,Yb (50 mg) was 24.32% higher than that of TiO 2 /(Ca,Y)F 2 :Tm,Yb in 90 min. And its antibacterial rates against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) were enhanced by 38.68% and 25.89% compared to TiO 2 /(Ca,Y)F 2 :Tm,Yb, respectively.
研究领域:
材料科学
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环境科学
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生物学
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DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2026
·
IF 11.3
Qing Qiu,Xuejian Sun,Han Li,Dandan Zhou,Hongliang Huo
Solid plastic waste has become a pressing environmental challenge worldwide. Tenebrio molitor possesses a unique ability to ingest plastics and straw. In this study, a dominant bacterial strain was isolated from its gut under the combined induction of polystyrene (PS), polyethylene (PE), and lignin, and was identified as Lysinibacillus fusiformis Tm-07. Genome sequencing revealed that Tm-07 harbors a wide range of genes related to carbon metabolism. Further investigations demonstrated that Tm-07 can form biofilms on plastic surfaces and secrete extracellular enzymes, thereby reducing surface hydrophobicity and generating new functional groups; notably, PS and PE as carbon sources significantly enhanced bacterial survival. Transcriptomic analysis revealed that multicopper oxidase laccase was the key enzyme markedly upregulated under PS, PE, and lignin conditions. Combined with degradation product analysis, the molecular mechanisms underlying Tm-07-mediated PS and PE degradation were elucidated, and a corresponding degradation model was proposed. This study provides an important microbial resource and molecular insights for plastic biodegradation.
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DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2019
·Vol. 7
·期 5
·1321-1329
·
IF 6.641
Daqin Chen,Yue Liu,Jiangkun Chen,Hai Huang,Jiasong Zhong,Yiwen Zhu
Efficient dual-modal luminescence is highly desired for applications in high security anti-counterfeiting. In the present work, Yb3+/Ln3+/Mn4+ (Ln = Er, Ho, and Tm) tri-doped Na3ZrF7 phosphors were fabricated via oil–water interface cation exchange using Yb3+/Ln3+:Na3ZrF7 as the exchanging hosts. The as-prepared products exhibited typical Mn4+ red down-shifting luminescence under UV light excitation and Er3+ red, Ho3+ yellow and Tm3+ near-infrared multi-color upconversion emissions under 980 nm laser excitation. The Mn4+ dopants in the Na3ZrF7 host experienced strong crystal-field strength Dq of 3.63 and showed superior thermal stability with up to 90% of the initial emission intensity retained at 448 K. Steady-state and time-resolved emission spectra verified that there was no detrimental energy transfer interaction between Mn4+ and Ln3+, enabling bright and eye-visible bi-functional emissions for the present products. As a consequence, the as-prepared phosphors were demonstrated to be applicable in anti-counterfeiting by a proof of concept experiment of fluorescent labeling for specially designed patterns.
研究领域:
材料科学
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光学
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纳米技术
·
化学
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2024
·
IF 13.3
Rujun Yang,Long Chen,Cunjian Lin,Honghui Huang,Zishuang Wu,Chenhan Zhan,Yixi Zhuang,Rong-Jun Xie
Photochromism and persistent luminescence (PersL) are two fascinating light-responsive effects in phosphors, both of which have found widespread applications in optical switching, optical anticounterfeiting and information storage. However, the relationship between photochromism and PersL has not been clarified, thus greatly limiting the use and design of the light-responsive materials in multifunctional applications. Herein, taking BaMgSiO 4 :Eu 2+ , TM (TM = transition metal: Fe, Co and Cr) as model materials, we first reveal that photochromism and PersL could be two independent photophysical effects, although they are both related to the charge carrier trapping/detrapping processes. Notably, photochromism and PersL show have different responses to light wavelengths, and the depth of traps involved in the two effects is also quite different. Moreover, by codoping different transition metal elements, we obtain the largest reflectance difference of ∼71 % among inorganic photochromic materials reported thus far, and demonstrate interesting multicolor photochromism, including magenta, golden and pink. Based on their distinct response to light and temperature, a multi-functionalized optical anticounterfeiting technology is proposed, which may open up a new avenue for applying the light-responsive materials in flexible electronics and wearable devices.
研究领域:
材料科学
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光学
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光子学
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纳米技术
·
化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2025
·
IF 7.3
Yun Yi,Kaixu Yang,Rongfeng Hu,Fei Liu,Chaochuang Yin,Jianxin Cao,Zheng Chen
Enhancing the surface and structural stability has been a research focus of nickel-rich layered cathode materials in lithium-ion batteries (LIBs). This work introduced a dual-functional modification strategy. LZMP is coated on the LiNi0.90Co0.05Mn0.05O2 (NCM90) particle surface to protect the cathode particles from erosion by air and acidic electrolyte, suppressing side reactions between the cathode and H2O, CO2, and HF, and hence enhances the stability of the cathode–electrolyte interphase film. Meanwhile, NCM90 is doped with Zr4+ and Mg2+, which substitute for Ni3+ in the lattice transition metal layer and Li+ in the lithium layer, respectively. Zr4+ forms a stronger Zr–O bond, while Mg2+ performs as a pillar ion, suppressing variations of the lattice parameters and maintaining the layered structure during cycling. The enhanced surface and bulk structural stabilities improve the cycling and rate performances of the cathode material. At 25 °C, 1C, and 2.7–4.3 V, the initial discharge specific capacity and the capacity retention after 200 cycles of 1%LZMP–NCM90 were 180.9 mAh g–1 and 86.0%, respectively, exceeding those of NCM90 (172.7 mAh g–1 and 76.4%). In summary, the LZMP modification synergistically alleviates the surface and bulk structure deterioration, thus preserving the electrochemical performance and improving the structural and cycling stability of NCM90.
研究领域:
材料科学
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电化学
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产品关联
DOI
高影响因子
JOURNAL OF LUMINESCENCE
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2022
·
IF 4.171
Gen Li,Yaqi Wang,Min Tao,Siqi Chen,Bozhi Zhou,Quan Li,Xin Li,Heming Deng,Hao Huang,Haoshuang Gu,Yuebin Li
Developing efficient strategies to fabricate planar photoluminescence scintillators is of great importance to explore X-ray detectors with new platform. Rare-earth (RE) doped Lu 2 O 3 thin films are successfully fabricated by mild aqueous phase electrochemical deposition on ITO/glass substrates with low-temperature post-annealing treatment. The as-prepared Lu 2 O 3 :RE 3+ (RE = Eu, Tb and Tm) thin films exhibit steerable thickness, high transparency in the visible-NIR range, and low transmittance at UV band mainly due to the oxygen-metal (O 2- -RE 3+ ) charge transfer processes and the 4f-4f transitions of the RE 3+ . The Lu 2 O 3 :RE 3+ thin films emit intense red, green and blue (RGB) photoluminescence, which mainly correspond to the 5 D 0 - 7 F 2 transition of Eu 3+ , 5 D 4 - 7 F 5 transition of Tb 3+ and 1 G 4 - 3 H 6 transition of Tm 3+ respectively. Moreover, the transparent Lu 2 O 3 :RE 3+ thin films also exhibit high sensitivity and linearity luminescence to the X-ray stimulation in a dose rate from 30 to 160 mGy s −1 . This rapid and energy-saving synthesis show high efficiency to fabricate rare-earth doped thin-film with a tunable optical performance for optoelectrical application in the fields of solar light concentrators, agricultural light conversion thin films, biosensors , photodetectors and especially the X-ray detectors.
研究领域:
材料科学
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光学工程
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医学影像
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产品关联
DOI
高影响因子
JOURNAL OF BONE AND MINERAL RESEARCH
·
2023
·Vol. 38
·期 4
·556-567
·
IF 6.2
Ruiye Bi,Xueting Luo,Qianli Li,Peiran Li,Haohan Li,Yi Fan,Binbin Ying,Songsong Zhu
Temporomandibular joint (TMJ) growth requires orchestrated interactions between various cell types. Recent studies revealed that fibrocartilage stem cells (FCSCs) in the TMJ cartilage play critical roles as cell resources for joint development and repair. However, the detailed molecular network that influences FCSC fate during TMJ cartilage development remains to be elucidated. Here, we investigate the functional role of Igf1 in FCSCs for TMJ cartilage growth and homeostasis by lineage tracing using Gli1-CreER + ; Tm flfl mice and conditional Igf1 deletion using Gli1-/Col2-CreER + ; Igf1 fl/fl mice. In Gli1-CreER + ; Tm flfl mice, red fluorescence + (RFP + ) FCSCs show a favorable proliferative capacity. Igf1 deletion in Gli1 + / Col2 + cell lineages leads to distinct pathological changes in TMJ cartilage. More serious cartilage thickness and cell density reductions are found in the superficial layers in Gli1-CreER + ; Igf1 fl/fl mice. After long-term Igf1 deletion, a severe disordered cell arrangement is found in both groups. When Igf1 is conditionally deleted in vivo, the red fluorescent protein-labeled Gli1 + FCSC shows a significant disruption of chondrogenic differentiation, cell proliferation, and apoptosis leading to TMJ cartilage disarrangement and subchondral bone loss. Immunostaining shows that pAkt signaling is blocked in all cartilage layers after the Gli1 + -specific deletion of Igf1 . In vitro, Igf1 deletion disrupts FCSC capacities, including proliferation and chondrogenesis. Moreover, the deletion of Igf1 in FCSCs significantly aggravates the joint osteoarthritis phenotype in the unilateral anterior crossbite mouse model, characterized by decreased cartilage thickness and cell numbers as well as a loss of extracellular matrix secretions. These findings uncover Igf1 as a regulator of TMJ cartilage growth and repair. The deletion of Igf1 disrupts the progenitor capacity of FCSCs, leading to a disordered cell distribution and exaggerating TMJ cartilage dysfunction. © 2023 American Society for Bone and Mineral Research (ASBMR).
研究领域:
发育生物学
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干细胞生物学
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骨科
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分子生物学
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病理学
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DOI
PubMed
高影响因子
JOURNAL OF LUMINESCENCE
·
2019
·
IF 2.961
Yuan Zhong,Shujie Gai,Yimei Yang,Mao Xia,Ye Zhang,Fanshan Qiu,Fang Xiang,Zhi Zhou
Green phosphor is an essential component in phosphor-converted white light-emitting diodes (pc-LEDs). Herein, a novel green-emitting phosphate phosphor Sr 8 ZnY(PO 4 ) 7 :Eu 2+ (SZYP:Eu 2+ ) was synthesized through hydrothermal reaction method. The crystal structure, photoluminescence properties as well as thermal stability of SZYP:Eu 2+ were investigated systematically. SZYP:Eu 2+ can be efficiently excited by n-UV light in the range from 220 to 550 nm and shows a broad emission band centered at 520 nm with a full width at half maximum of 86 nm. The optimized doping concentration of Eu 2+ was determined to be 0.02 mol. With the increase of Eu 2+ content, a subtle red shift about 4 nm in emission spectra was detected. SZYP:Eu 2+ also shows comparable thermal stability (45% at 150 °C) and it can be further varied to 44, 40 and 51% by co-doping with Pr 3+ , Tm 3+ and Yb 3+ , respectively. The white LED device blended with SZYP:Eu 2+ shows excellent electroluminescence (EL) properties. The low correlated color temperature (4791 K) and ultrahigh color rendering index (95.8) imply that this phosphor may find a potential application in high-quality white LEDs.
研究领域:
材料科学
·
光学工程
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DOI
高影响因子
ACS Applied Bio Materials
·
2026
·
IF 5.6
Qi Cai,Yue Li,Xuewei Ba,Piaoping Yang
The aberrant vascularization and uneven vascular distribution stemming from rapid tumor cell proliferation culminate arouse intra-tumoral hypoxia, which substantially compromises the therapeutic response to conventional chemotherapy, as well as photothermal therapy (PTT) and photodynamic therapy (PDT). In this work, we present an innovative α-NaYbF4:Tm@Cu2-xSe@ZnFe2O4-DOX nanoplatform that synergistically integrates PTT, Fenton reaction-enhanced chemodynamic therapy, PDT, and doxorubicin (DOX)-based chemotherapy under 980 nm near-infrared (NIR) light activation and weakly acidic environment-initiation. The 10 nm cubic-phase α-NaYbF4:Tm up-conversion cores were initially synthesized. Subsequently, low atomic number (Z) Cu2-xSe nanocrystal grown as photo-thermal conversion agent demonstrated significantly stronger X-radiation (X-ray) attenuation capabilities and enhanced computed tomography (CT) imaging performance compared to clinically used iopromide. Furthermore, zinc ferrite (ZnFe2O4) shell was obtained in hydrothermal synthesis manner. The 980 nm NIR-excited α-NaYbF4:Tm nanoparticles undergo efficient energy down-conversion, emitting photons that perfectly match the absorption spectrum of ZnFe2O4, thereby maximizing reactive oxygen species (ROS) generation through bandgap-engineered photoconversion. The tumor's glycolytic activity creates a hydrogen peroxide (H2O2)-rich microenvironment, enabling ZnFe2O4-mediated Fenton-like reactions that produce hydroxyl radicals (•OH) radicals, ultimately triggering oxidative damage and apoptotic cell death. It is noted that dual-mode photothermal therapeutic efficacy was achieved by Cu2-xSe and ZnFe2O4 as photothermal nanocrystal with up-conversion luminescence (UCL), magnetic resonance imaging (MRI) and CT multimodal imaging. DOX as anticancer chemotherapeutics was conjugated to form α-NaYbF4:Tm@Cu2-xSe@ZnFe2O4-DOX nanoplatforms. It remains effectively release of large quantities of DOX at tumor part conferred response to excessive lactic and carbonic acids generated in cancer cells. Our research may provide an insight for generalizing enhanced synergetic performance by NIR light-mediated PTT, Fenton reaction, PDT and chemotherapy. It is not a simple assembly of known components, but rather a multi-functional synergistic system constructed through ingenious core-shell structural design, capable of responding to near-infrared light and the tumor microenvironment. For the first time, this system seamlessly integrates up-conversion luminescence-mediated PDT, dual photothermal agent-enhanced PTT, self-supplying H2O2 Fenton reactions, and acid/heat dual-responsive chemotherapy into a single nanoplatform. Additionally, it incorporates multimodal imaging capabilities, providing an innovative and comprehensive solution to overcome the clinical challenge of tumor hypoxia.
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DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2025
·
IF 3.5
Congxue Su,Huini Mo,Juanling Pan,Wenlong Tao,Jun Fan,Min Cheng,Sisi Pan,Haibin Li,Ruijuan Wang,Xingliu Qin,Huanfu Zhou
Two novel low-firing KBaHo(MoO 4 ) 3 (KBHM) and KBaTm(MoO 4 ) 3 (KBTM) ceramics were synthesized using a conventional solid-state method. Rietveld refinement results of the X-ray diffraction (XRD) have verified that the KBHM and KBTM ceramics are classified within a monoclinic crystal system with C2/c space group. The correlations among structural characteristics, bond features and microwave dielectric properties were comprehensively studied utilizing bond valence, packing fraction, Raman spectroscopy, global instability index, and Phillips−Van Vechten−Levine (P−V−L) theory. The compressive effects exerted by the K + and Ba 2+ mainly contributed to the higher ε theo compared to the ε corr . According to the analysis grounded in P−V−L, the lattice energy and bond energy associated with the Mo−O bond played a substantial role in influencing the Q × f and τ f . Furthermore, the Q × f values had relation to the material's density and its packing fraction. The excellent microwave dielectric properties ( ε r = 8.74, τ f = −30.4 ppm/°C and Q × f = 42, 071 GHz) were obtained in the KBHM ceramic sintered at 800 °C. By comparison, KBTM ceramic sintered at 810 °C exhibited superior properties ( ε r = 8.81, Q × f = 52, 946 GHz and τ f = −31.6 ppm/°C). Moreover, KBTM ceramic can be co-fired with Ag without chemical reactivity, which makes it a promising candidate for low temperature co-fired ceramic (LTCC) technology.
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DOI
高影响因子
CRYSTENGCOMM
·
2023
·
IF 3.1
Aihua Zhou,Jiaxin Yang,Yan Li,Chengguo Ming,Yuanxue Cai,Yumiao Pei
Luminescence thermometry has recently been gaining popularity in science and technology fields. However, most reported works have used the fluorescence intensity ratio (FIR) to obtain the temperature based on thermally coupled energy levels (TCLs), which have hindered the sensitivity of the technique and limited its applications. Here, NaYF4:Yb/Tm@NaYF4:Yb/Ho microcrystals were prepared using a hydrothermal method. Based on the non-thermally coupled energy levels (NTCLs) of the double luminescent ionic centers Tm3+ and Ho3+, the materials exhibited temperature-dependent luminescence in the range of 304 K to 574 K. The maximum sensitivities were found to be Sa = 0.135 K−1 at 574 K and Sr = 1.101% K−1 at 484 K based on red (Tm3+) and green (Ho3+) emission bands. This study has provided a promising new strategy to break the TCL restriction and has shown the material to have potential applications in luminescence thermometry.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）