POLYMER
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2013
·Vol. 54
·期 13
·3385-3391
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IF 3.379
Hai-Mu Ye,Yun-Yang Song,Jun Xu,Bao-Hua Guo,Qiong Zhou
Inclusion complexes formed from host small molecules and guest polymers have provided a novel platform to study both the physical properties of isolated polymer chains and crystallization behavior of host molecules. In this report, we have studied the crystalline structure, melting behavior and infrared information of inclusion complexes formed between polyethylene glycol oligomers and urea molecules. The effect of molecular weight and terminal group of guest PEG oligomer on the melting behavior of inclusion complex is presented. FTIR spectra reveal that terminal –OH of PEG is hydrogen-bonded to urea in inclusion complex, while the terminal –OCH 3 is free. The melting behaviors of complexes are interpreted using either Gibbs–Thomson equation for lamellar crystals with definite channel length or Flory equation for crystals with infinite channel length and included defects. The results show that the interaction between terminal –OH in PEG chain and urea induces larger interfacial free energy or stronger defect effect, compared to the terminal –OCH 3 in the inclusion complexes, which results in the particular order of melting point: T m (DPEG500UIC) > T m (MPEG550UIC) > T m (HPEG600UIC).
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高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2017
·
IF 3.151
Kewen Li,Chao Zhou,Shunli Liu,Fang Yao,Guodong Fu,Liqun Xu
Hydrogels have been considered as promising materials in tissue engineering and biomedical areas. However, the weak and brittle nature of common synthetic hydrogels largely hinders their potential applications. Therefore, it is challenging to fabricate tough hydrogels for biomedical applications . In this manuscript, well-defined and thermo-responsive polyurethane-poly(ethylene glycol) (PU-PEG) hydrogels were prepared via thermally-induced copper-catalyzed 1,3-dipolar azide-alkyne cycloaddition (CuAAC) using azido-pendent PU-PEG and dialkynyl PEG as the gel precursors. The physical properties of the as-formed hydrogels were investigated by swelling ratios and mechanical tests. The PU-PEG hydrogels not only possess thermo-responsive and excellent mechanical properties, but also exhibit good biocompatibility .
研究领域:
生物医学工程
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材料科学
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组织工程
·
高分子化学
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CHEMICAL ENGINEERING JOURNAL
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2026
·
IF 12.5
Kaiqi Du,Guangpeng Chen,Hao Pan,Liting Fan,Huiping Xu,Wenqiu Su,Shaolong Wan,Wenjing Hong
Base-catalyzed transesterification was studied for PGMEA synthesis avoiding acid and water. • EtONa was identified as the catalyst and its deactivation mechanism was EA Claisen condensation. • In situ formation of sodium PGME can partially suppress catalyst deactivation at low loadings. • 99.90% PGMEA with negligible metal and moisture was achieved by customized rectification. • Process simulation of two-stage distillation shows that electronic-grade PGMEA is achievable. Propylene glycol methyl ether acetate (PGMEA) is an essential electronic-grade solvent in semiconductor manufacturing. However, the conventional esterification route introduces acid and water, requiring extensive purification to meet ultra-stringent quality standards. Herein, an alternative transesterification process with base catalysts that inherently avoids acid and water formation was systematically investigated. Sodium ethoxide (EtONa) exhibited the highest catalytic activity among the bases examined. Catalyst deactivation was traced to EtONa-catalyzed Claisen condensation of ethyl acetate (EA), while the formation of sodium PGME (PGMENa) partially suppressed this effect at low catalyst loadings. Using a customized rectification process, PGMEA with 99.90% purity and negligible metal content was obtained, and process simulation results indicate that electronic-grade purity (99.9999%) is achievable. This work demonstrates a practical and industrially viable route for the production of ultra-high-purity PGMEA.
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Energy Material Advances
·
2026
·
IF 17.4
Huan Ge,Yi Ma,Ning Jian,Lin Wang,Yaoyue Yang,Jing Yu,Jordi Arbiol,Haiting Wang,Jiaming Ding,Luming Li,Andreu Cabot,Junshan Li
Electrocatalytic ethylene glycol oxidation (EGOR) is central to energy conversion andpolyethylene terephthalate (PET) plastics upcycling, yet its deployment is limited by thescarcity of selective, durable anodes. We report cobalt nickel diselenide (Co1-xNixSe2)nanoparticles (NPs) prepared by hydrothermal synthesis, where Ni incorporationmodulates the spin states of Co and tailors the electronic structure. In situ Fouriertransform infrared spectroscopy identifies glycolaldehyde and glyoxylic acid as keyintermediates, revealing a Ni-induced shift toward a C–C bond-cleavage pathway. Anequimolar Ni/Co composition delivers ≈90% Faradaic efficiency (FE) to formate at 1.6 Vversus RHE while sustaining ~100 mA cm-2 over 10 h testing. The enhanced activity andselectivity arise from spin-state optimization, which strengthens adsorption of reactionintermediates, promotes selective dehydrogenation and controlled C–C scission, andsuppresses over-oxidation. These results establish spin-state engineering as an effectivelever to steer the electrooxidation pathways of small organic molecules and guide thedesign of high-performance anode catalysts.
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CANADIAN JOURNAL OF CHEMICAL ENGINEERING
·
2022
·Vol. 101
·期 7
·4217-4229
·
IF 2.5
Jia Wang,Rongchun Shen,Yueqiang Cao,Wei Li,Jinghong Zhou
1,2-butanediol (1,2-BDO) and 1,2-propanediol (1,2-PDO) are inevitably side produced in the ethylene glycol (EG) production processes from non-petroleum routes, but are very difficult to separate by the ordinary distillation method because of the closeness of their boiling temperatures to EG, thus compromise the economy of these processes. The azeotropic distillation process using 1-octanol (CPO) as an entrainer to separate EG and 1,2-BDO mixture with or without 1,2-PDO was studied in this paper. Four binary vapour–liquid equilibrium data of EG-1,2-BDO, EG-CPO, 1,2-BDO-CPO, and 1,2-PDO-CPO were measured using an Ellis equilibrium kettle and regressed with the thermodynamic model of non-random two liquid to obtain the corresponding binary interaction parameters. On this basis, azeotropic distillations with CPO as an entrainer were designed to separate EG and 1,2-BDO with or without 1,2-PDO. The complete separation processes, including the azeotropic distillation and CPO recovery process consisting of extraction with H 2 O and subsequent distillation, were simulated and optimized with Aspen Plus for both the EG-1,2-BDO binary mixture and the EG-1,2-BDO-1,2-PDO ternary mixture. The simulation results show that the azeotropic distillation method with CPO as an entrainer can effectively separate the mixture of EG-1,2-BDO and EG-1,2-BDO-1,2-PDO, achieving EG of 99.90% purity with 99.98% recovery and 1,2-BDO of 99.30% purity with 99.45% recovery for the binary mixture, and achieving EG of 99.90% purity with 99.80% recovery, 1,2-BDO of 99.35% purity with 99.35% recovery, and 1,2-PDO of 90.59% purity with 94.38% recovery for the ternary mixture. These processes are promising for industrial application and can significantly improve the economy of non-petroleum EG production.
研究领域:
化学工程
·
分离技术
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Biomaterials Science
·
2019
·Vol. 7
·期 6
·2520-2532
·
IF 5.251
Xu-Qi Kang,Yue Qiao,Xiao-Yang Lu,Sai-Ping Jiang,Wei-Shuo Li,Xiao-Juan Wang,Xiao-Ling Xu,Jing Qi,Yong-Hong Xiao,Yong-Zhong Du
Multiple drug resistance and the increase in the appearance of superbugs together with the exceedingly scant development of new potent antibiotic drugs pose an urgent global medical threat and imminent public security crisis. In the present study, we fabricated well-dispersed tocopherol polyethylene glycol succinate (TPGS)-capped silver nanoparticles (AgNPs) of about 10 nm in size. The hollow structure of the TPGS-capped AgNPs (TPGS/AgNPs) was confirmed and applied to load antibiotics. The TPGS/AgNPs proved to be able to cross the bacterial cell wall and penetrate into bacteria, thereby delivering more of the antibiotic to the interior of bacteria and thus enhancing the in vitro antibacterial effect of the antibiotic, even overcoming the drug-resistance in drug-resistant E. coli and Acinetobacter baumannii. It was found that the TPGS modification in the TPGS/AgNPs could decrease the activity of the efflux pumps AdeABC and AdeIJK in drug-resistant Acinetobacter baumannii via inhibiting the efflux pump genes adeB and adeJ, thus increasing the accumulation of the delivered antibiotic and overcoming the drug-resistance. Tigecycline delivered by TPGS/AgNPs could effectively antagonize drug-resistance in an acute peritonitis model mice, thereby increasing the survival rate and alleviating the inflammatory response. TPGS/AgNPs were developed as a novel and effective antibiotic delivery system and TPGS was demonstrated to have great potential as a pharmaceutical excipient for use in drug-resistant infection therapy.
研究领域:
药剂学
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纳米技术
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微生物学
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传染病学
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高影响因子
Nanoscale
·
2025
·Vol. 17
·期 39
·23010-23021
·
IF 5.1
Binqi He,Yunping Ma,Xinyue Xiang,Sifan Sun,Qianzuo Liu,Ting Zhang,Maiyong Zhu,Tie Li
The development of high-performance electrochemical catalysts capable of ultrasensitive detection of small molecules remains a significant challenge. Emerging two-dimensional materials, particularly metallenes such as Pd metallene, have demonstrated considerable potential in addressing these challenges. However, several critical limitations remain, including the need for further enhancement of electrochemical activity, detection sensitivity, and molecular selectivity. In this study, a one-step hydrothermal approach was employed to synthesize porous PdPr bimetallene alloys with a semi-transparent, wrinkled architecture, which function as high-performance catalysts in flexible electrochemical sensors. These materials exhibit excellent sensitivity and selectivity toward ethylene glycol detection. The incorporation of Pr not only induces unique synergistic lattice distortion effects but also enhances the thermodynamic stability of defect sites, which act as efficient electron-transfer channels and significantly activate the catalytic centers. This structural engineering significantly improves both electronic conductivity and structural stability, while also accelerating electron-transfer kinetics and enhancing the activity of the ethylene glycol oxidation reaction (EOR). This work not only demonstrates the effectiveness of active-site engineering in PdPr bimetallene for improved catalytic performance but also broadens the application of metallenes in the sensing of small molecules, aligning with current trends in advanced sensing technologies.
研究领域:
材料科学
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电化学
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纳米技术
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传感器与探测器
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催化
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yunhua Bai,Xiong-Fei Zhang,Mengjiao Yu,Jianfeng Yao
Deep eutectic solvents (DESs) hold great potential in biorefining because they can efficiently deconstruct the recalcitrant structure of lignocellulose . In particular, inorganic salts with Lewis acids have been proven to be effective at cleaving lignin–carbohydrate complexes. Herein, a Zr-based DES system composed of metal chloride hydrate (ZrOCl 2 ·8H 2 O) and ethylene glycol (EG) was designed and used for poplar powder pretreatment . Zr 4+ -based salts provide sufficient acidity for lignocellulose depolymerization . The acidity of the DES was analysed by the Kamlet-Taft solvatochromic parameter, and the results demonstrated that the acidity can be regulated by the DES composition. Under the optimum conditions (ZrOCl 2 ·8H 2 O:EG molar ratio of 1:2), the DES pretreatment removes nearly 100 % hemicellulose and 94.7 % lignin. The recovered lignin exhibited a low polydispersity of 1.7. The cellulose residues deliver an efficiency of 94.4 % upon enzymatic digestion. Moreover, the DES can be easily recovered with high yield and purity, and the recycled DES still maintains high delignification and enzymatic hydrolysis efficiencies. The proposed DES pretreatment technology is promising for biomass valorization.
研究领域:
生物化学
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生物质能
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材料科学
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PubMed
高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 3
·604
·
IF 5.3
Yan Zhu,Qianhui Wei,Qingxi Jin,Gangrong Li,Qingzhu Zhang,Han Xiao,Tengfei Li,Feng Wei,Yingchun Luo
Accurate monitoring of blood glucose levels is crucial for the diagnosis of diabetes patients. In this paper, we proposed a simple “mixed-catalyzer layer” modified silicon nanowire field-effect transistor biosensor that enabled direct detection of glucose with low-charge in high ionic strength solutions. A stable screening system was established to overcome Debye screening effect by forming a porous biopolymer layer with polyethylene glycol (PEG) modified on the surface of SiNW. The experimental results show that when the optimal ratio (APTMS:silane-PEG = 2:1) modified the surface of silicon nanowires, glucose oxidase can detect glucose in the concentration range of 10 nM to 10 mM. The sensitivity of the biosensor is calculated to be 0.47 μAcm−2mM−1, its fast response time not exceeding 8 s, and the detection limit is up to 10 nM. This glucose sensor has the advantages of high sensitivity, strong specificity and fast real-time response. Therefore, it has a potential clinical application prospect in disease diagnosis.
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高影响因子
Polymers
·
2023
·Vol. 15
·期 3
·564
·
IF 5
Huafen Wang,Huanhuan He,Jiaxiang Zhang,Juntao Liu,Yuwei Zhuang,Yuanyuan Yin,Zhiyong Ren,Yang Fu,Suqin He
Novel monomethoxy poly(ethylene glycol) (mPEG) modified hydroxylated tung oil (HTO), denoted asmPEG-HTO-mPEG, was designed and synthesized for drug delivery.mPEG-HTO-mPEG consists of a hydroxylated tung oil center joined by twomPEG blocks via a urethane linkage. The properties ofmPEG-HTO-mPEG were affected by the length of the mPEG chain. ThreemPEG with different molecular weights were used to preparemPEG-HTO-mPEG. The obtained threemPEG-HTO-mPEG polymers were characterized by nuclear magnetic resonance (NMR), Fourier transformation infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC) and gel permeation chromatography (GPC), respectively. Furthermore, the particle sizes ofmPEG-HTO-mPEG micelles were evaluated by dynamic light scattering (DLS) and transmission electron microscope (TEM). A critical aggregation concentration (CAC) ranged from 7.28 to 11.73 mg/L depending on the chain length of mPEG. The drug loading and release behaviors ofmPEG-HTO-mPEG were investigated using prednisone acetate as a model drug, and results indicated that hydrophobic prednisone acetate could be effectively loaded intomPEG-HTO-mPEG micelles and exhibited a long-term sustained release. Moreover, compared with HTO,mPEG-HTO-mPEG had no obvious cytotoxicity to HeLa and L929 cells. Therefore, monomethoxy poly(ethylene glycol) modified hydroxylated tung oilmPEG-HTO-mPEG may be a promising drug carrier.Keywords:hydroxylated tung oil;poly(ethylene glycol);drug delivery
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HIGH PERFORMANCE POLYMERS
·
2022
·
IF 1.73
Yihao Nie,Xibin Yi,Xinfu Zhao,Shimo Yu,Jing Zhang,Xiaochan Liu,Sijia Liu,Zhipeng Yuan,Minna Zhang
The cost of CO2 separation and energy consumption can be decreased through the use of CO2 adsorption. Due to the electron-rich heteroatoms in its network, polyimide (PI) has a remarkable affinity for CO2. Polyethylene glycol (PEG) can increase the layer spacing of polymers, so as to change the mass transfer of CO2 in it. Furthermore, the ether bond (-O-) in PEG has good affinity for CO2. In this study, PEG-1000 was introduced into PI aerogel by mild sol-gel method at low temperature, and freeze-drying was used to produce PI/PEG composite aerogels with directional pore structure. The effect of PEG-1000 content and directional pore structure of the PI/PEG composite aerogels on CO2 adsorption performance were further studied. The L-PI/PEG-4 composite aerogel, which contains 4 g PEG and is directionally frozen in liquid nitrogen, has a CO2 adsorption capacity of 16.76 cm3/g at 25°C and 1 bar. L-PI/PEG-4 aerogel also exhibits high CO2/N2 selectivity and adsorption cycle stability.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2022
·
IF 7.139
Bin Zou,Yangping Zhang,Fei Gao,Zhuolin Li,Caiqin Wang,Zhengying Wu,Dongqiong Wang,Yukou Du
The noble metal anodic catalysts with three-dimension (3D) chain-like network structure have been researched thoroughly due to their unique morphological characteristics. Herein, a novel scheme has been designed rationally to synthesize 3D PdPb nanochain networks (PdPb NCNs). Numerous nanochains were interlaced and stacked to form the nanonetworks, which were contributed to improving electrocatalytic performance. Abundant steps and kinks existed on the nanochain networks, which provided plentiful active sites to improve the electrocatalytic activity . In the subsequent electrochemical tests, the mass activity of Pd 65 Pb 35 NCNs was 4.47 A mg pd −1 , higher than other catalysts. Moreover, in the chronoamperometry and consecutive CV measurements, Pd 65 Pb 35 NCNs exhibited the best stability than other prepared samples. This work explored the rational synthesis of PdPb nanochain networks, and confirmed the excellent electrocatalytic performance in EGOR .
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