JOURNAL OF SOLID STATE CHEMISTRY
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2020
·
IF 2.726
Yumei Xiao,Dongning Liu,Cheng Liu,Yongchao Wang,Cuijuan Wang
Curcumin (CCM) is a natural ingredient with anti-cancer activity. However, the application of CCM is limited in clinical medicine due to its high hydrophobicity and low bioavailability. Hence, it is necessary for development of a feasible strategy for efficient drug delivery and cancer cell-selective targeting. In recent years, nano-scaled metal-organic frameworks (NanoMOFs) have received much attention as an attractive drug delivery carrier due to their unique features of their various sizes, adjustable pore structures , high stability, and easy surface modification. Here, we report a novel composite nanomaterial (denoted as ZIF-8&α-lip) for CCM loading by one-pot method. This synthetic method is simple and rapid, and the final product (CCM@ZIF-8&α-lip) can be obtained within 20 min. In addition, the obtained CCM@ZIF-8&α-lip shows greater growth inhibition of HepG2 cells in comparison with CCM@ZIF-8. Therefore, ZIF-8&α-lip can be used as an ideal drug carrier and propose a new strategy to improve nanoMOFs performance for efficient drug delivery.
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Journal of Materials Chemistry A
·
2021
·Vol. 9
·期 7
·4167-4175
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IF 12.732
Haoyu Li,Peng Mu,Jian Li,Qingtao Wang
Purification of highly emulsified oily wastewater is of significance but challenging due to the critical limitations of low efficiency and serious membrane blocking. Herein, inspired by the desert beetle's capability of water-collection in air, we first constructed an inverse desert beetle-like membrane to achieve oil capture in water, thus improving the separation performances of the surfactant-stabilized oil-in-water emulsion. The as-prepared nanofibrous membrane consists of hydrophobic/oleophilic ZIF-8 bumps and underlying underwater superoleophobic polyacrylonitrile (PAN), and possesses a similar structure to desert beetles but with opposite wettability. In the process of emulsion demulsification, besides the sieving effect of the underlying traditional underwater superoleophobic PAN membrane, the bumpy oleophilic ZIF-8 particles of the composite membrane can capture oil, thus strengthening the demulsification ability of the membrane. Furthermore, the separation efficiency of the inverse desert beetle-like membrane is up to 99.92% for surfactant-stabilized oil-in-water emulsion, which is superior to that of traditional single underwater superoleophobic PAN membranes lacking the hydrophobic bump structure. Moreover, for light oil-in-water emulsion, the permeation flux also increases because the captured tiny oil droplets can aggregate subsequently and grow large enough to detach from the underlying surface which greatly reduces the incidence of filter cake formation and congestion. This inverse desert beetle-like membrane opens up new avenues for designing advanced membranes in the oil/water emulsion separation field.
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BIOSENSORS & BIOELECTRONICS
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2020
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IF 10.257
Qian Ren,Junsong Mou,Yanmei Guo,Huiqi Wang,Xiyue Cao,Feifei Zhang,Jianfei Xia,Zonghua Wang
A simple homogeneous electrochemical aptasensor was designed by using target-responsive substrate releasing from aptamer-gated zeolitic imidazolate framework-8 (ZIF-8)-derived porous carbon nanocontainer. The nanocontainer (Z-700) was prepared by calcination of ZIF-8 at 700 °C. Z-700 had great biocompatibility, high surface areas and pore volume , especially the graphene-like π-rich structure, which was beneficial for adsorbing aptamer easily. The electroactive dyes methylene blue (MB) was then trapped in the pores of Z-700 and easily capped with aptamer as gatekeeper based on π-stacking interaction. Upon addition of target protein thrombin (Thb), the Thb could specifically recognize and combine with its aptamer to form complex. Thereafter, the aptamer bio-gate opened and the MB released from the pores, which could be detected on the screen-printed electrode. Under the optimized conditions, the proposed Thb aptasensor showed a wide detection range from 1 fM to 1 nM with a low detection limit of 0.57 fM. The strategy by using ZIF-8-derived porous carbon and aptamer bio-gate provides a promising scheme for developing simple, rapid, reliable and ultrasensitive bioassays, which has a great potential as a powerful tool in disease diagnosis and biomedicine.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2020
·
IF 4.65
Rui Li,Wei Li,Chun Jin,Qinyu He,Yinzhen Wang
ZIF-8@TiO 2 micron composite, one kind of new high-efficiency photocatalyst was prepared by hydrothermal method in this work. We compared the ability of ZIF-8, TiO 2 nanospheres and ZIF-8@TiO 2 to catalytically degrade tetracycline. The results of the characterization show that the TiO 2 nanospheres grow uniformly on the surface of ZIF-8, and ZIF-8 and TiO 2 are linked together by chemical bonds. The synergistic effect of ZIF-8 and TiO 2 greatly enhances the catalytic ability of the composite photocatalyst. In ZIF-8@TiO 2 micron composite, ZIF-8 provides a new way for photogenerated electron transfer as a charge separator, to reduce the charge recombination rate. Since the hybrid combines the advantages of ZIF-8 and TiO 2, ZIF-8@TiO 2 exhibits excellent ability to catalytically degrade tetracycline. The possible photocatalytic mechanism of the hybrid photocatalyst was also discussed.
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JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
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2020
·
IF 1.816
Kiran Abdullah,Xia Kong,Muhammad Imran,Ghulam Mustafa,Yanli Chen
A new hybrid material has been developed by mixing a sandwich-type double-decker, Eu[Pc(OC 4 H 9 ) 8 ] 2 = 2,3,9,10,16,17,23,24-octabutoxyphthalocyaninate] with acidified multiwalled carbon nanotubes (aMWCNTs) through non-covalent interactions. The UV-vis spectrum, X-ray diffraction and scanning electron microscope have been employed to reveal the J -aggregate mode and optimized morphology of Eu[Pc(OC 4 H 9 ) 8 ] 2 molecules in the Eu[Pc(OC 4 H 9 ) 8 ] 2 /aMWCNTs hybrid material. The gas-sensing devices based on this hybrid material are fabricated by a simple solvent-processing quasi-Langmuir–Shäfer (QLS) progress. The n -type and p -type response is shown by the Eu[Pc(OC 4 H 9 ) 8 ] 2 /aMWCNTs hybrid film at room temperature. The detection limit of the hybrid for ammonia and nitrogen dioxide gas is 0.5 ppm and 0.3 ppm, respectively.
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APPLIED SURFACE SCIENCE
·
2021
·
IF 6.707
Jinchang Xu,Guofeng Liang,Di Chen,Zilong Li,Hao Zhang,Jian Chen,Fangyan Xie,Yanshuo Jin,Nan Wang,Hui Meng
H 2 -O 2 proton exchange membrane fuel cells (PEMFCs), one of the applications of hydrogen energy with specific energy density of 143 MJ/kg, might be a promising alternative to replace the use of fossil energy. The key to accelerate the application of PEMFCs is to design an efficient non-precious metal catalyst to lower the overpotential of the cathode oxygen reduction reaction (ORR). Herein, we developed a novel iron and nitrogen doped carbon (FeNC) catalyst using ferrocene as iron source, ZIF-8 as organic framework as well as the main carbon source. The regular morphology of ZIF-8 and ferrocene can prevent active sites from agglomeration, resulting a homogenous distribution of Fe, N and C. Moreover, the high specific area, porous structure and abundant catalytic Fe and N species gave rise to the ORR performance of the catalyst. As a result, the as-prepared FeNC catalyst showed an onset and half-wave potential of 0.95 V and 0.78 V in 0.1 M HClO 4 with 1600 rpm, respectively. The catalysts were also applied in a PEMFC as the cathode catalysts with an open circuit voltage of more than 0.9 V and a maximum power density of 601 mW/cm 2 . Additionally, the as-prepared FeNC-1:30 catalyst showed a current density of 380 mA/cm 2 at 0.7 V, which outperformed other as-prepared catalysts.
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ENVIRONMENTAL RESEARCH
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2021
·
IF 6.498
Rui Luo,Junwen Wu,Jing Zhao,Dong Fang,Zongtang Liu,Lin Hu
The non-radical oxidation processes of persulfate activation by carbon materials have shown great potential for industrial and saline wastewater treatment . Recently, metal-organic frameworks (MOFs) as an emerging precursor have been widely used for fabricating functional carbon materials. Herein, we reported ZIF-8 derived defect-rich nitrogen-doped carbon (ZCNs) via NaCl-assisted pyrolysis for efficient non-radical activation of peroxydisulfate to degrade rhodamine B (RB). All samples exhibited excellent catalytic activity , and ZCN-900 (pyrolyzed at 900 °C) was found to be the most active, able to degrade 96 % of RB quickly within 10 min. Quenching tests and electron paramagnetic resonance (EPR) analyses suggested that the singlet oxygen ( 1 O 2 ) dominated the degradation process by a non-radical pathway. Furthermore, the effect of anions and water quality on RB oxidation were investigated, and ZCN-900/PDS system showed great resistance to the anions and natural organic matters (NOM). This work may provide a significant addition to MOF-based functional materials for environmental remediation based on the results above.
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高影响因子
Advanced Materials Interfaces
·
2019
·Vol. 7
·期 2
·1901490
·
IF 4.713
Yixing Zhan,Yating Wang,Ming Wang,Xiaoqing Ding,Xinlong Wang
The nano metal–organic framework particles (nano ZIF-8) are grafted onto the surface of short carbon fibers (SCFs) by a facile in situ growth method in order to functionalize SCFs. The morphology, crystal structure, and chemical element composition of modified SCFs (ZIF-8@SCFs) are investigated. The grafted nano-ZIF-8 could remarkably enhance the roughness, polarity, and wettability of SCFs surface and promote the curing reaction of epoxy composites. The tensile strength, flexural strength, elastic modulus, toughness, and impact strength of the epoxy composites with 1 wt% ZIF-8@SCFs are increased by 25%, 31%, 51%, 28%, and 42% compared to that of the composites with 1 wt% SCFs, respectively. Furthermore, the storage modulus ( E ′) and glass transition temperature ( T g ) are enhanced from 2558 MPa and 108.2 °C to 3000 MPa and 147.6 °C. The significant improvement in mechanical and thermomechanical properties of the prepared composites could be ascribed to the ameliorated wettability, enhanced mechanical interlock, and increased chemical bonding induced by ZIF-8@SCFs.
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Catalysis Science & Technology
·
2019
·Vol. 9
·期 10
·2673-2681
·
IF 5.726
Bing Hu,Yazhi Yin,Zixin Zhong,Dengdeng Wu,Guoliang Liu,Xinlin Hong
Maximizing the Cu–ZnO interface is regarded as the best strategy to promote methanol synthesis activity over CuZn catalysts. Reducing the ZnO particle size can enhance the Cu–ZnO interaction, but its synthesis with a sub-5 nm size still remains a challenge. Moreover, the fabrication of an active powder catalyst with an inverse ZnO/Cu configuration is still very rare. In this work, we report a facile synthesis of inverse ZnO/Cu catalysts by direct calcination of Cu@ZIF-8 (zeolitic imidazolate framework-8). The particle size of ZnO and Cu can be tuned by changing the Cu loading as well as the calcination temperature. Importantly, inverse ZnO/Cu catalysts with sub-5 nm ZnO were obtained under gentle calcination at 623 K. In the CO2 hydrogenation reaction, the highest methanol synthesis activity reached 933 g kgcat−1 h−1 at 533 K and 4.5 MPa, with a high turnover frequency (TOF) of 0.013 s−1, over an optimized C2Z-623 catalyst, which exceeds the commercial CuZnAl catalyst (HiFuel R120, Johnson Matthey) and has ranked the top reported value over advanced CuZn catalysts under comparable conditions. Such excellent activity is attributed to the inverse structure of Cu particles covered by sub-5 nm ZnO, which promotes the intimate Cu–ZnO interface with enhanced SMSI. Moreover, we find that the methanol turnover frequency (TOF) monotonically increases with decreasing the particle size of ZnO as well as Cu. It is proposed that reducing the ZnO size favors the spillover of reducible ZnOx species onto the Cu surface while lowering the Cu size is responsible for the enhanced amount of exposed Cu steps for accommodating Zn species, both of which could facilitate the formation of Zn covered Cu steps as active sites for methanol synthesis.
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JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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2019
·
IF 2.983
Zhenqun Li,Jia Wu,Li Jia
Detection of amino acids (AAs) in blood is helpful to diagnose some diseases. In this work, a method is developed for determination of trace amounts of AAs in bovine blood by combining solid phase extraction (SPE) and capillary electrophoresis (CE). Zeolitic imidazolate framework-8 (ZIF-8) nanoparticles are prepared and used as adsorbents to simultaneously extract three AAs (tryptophan, tyrosine, phenylalanine). Under the optimum extraction conditions, the extraction efficiencies of ZIF-8 for AAs are 95.1% (tryptophan), 91.1% (tyrosine), and 90.1% (phenylalanine), respectively. Interestingly, ZIF-8 demonstrates good extraction ability for AAs in high concentration of acetonitrile (ACN) aqueous solutions. Thus, they can be directly used to extract AAs from the deproteinized blood sample using ACN. An α-cyclodextrin-mediated cation selective exhaustive injection-sweeping CE method is developed for analysis of the extracted AAs. The detection limits for AAs range from 0.13 to 0.37 μg mL −1 using the SPE/CE method. Standard addition method is used to evaluate the feasibility of the method in bovine blood samples. The standard addition curves demonstrate good linearity with determination coefficient > 0.9912.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Hongye Yan,Lei Jiao,Hengjia Wang,Weiqing Xu,Yu Wu,Wenling Gu,Dan Du,Yuehe Lin,Chengzhou Zhu
Enzyme-linked immunosorbent assay (ELISA) has been widely used in the area of biological analysis, while there are still some challenges getting in the way to ensure both excellent sensitivity and reliable accuracy. To overcome these obstacles, we simulated the “smart” sense-and-treat carriers in a drug delivery system to fabricate an improved ELISA, employing zeolitic imidazolate framework-8 (ZIF-8) as the carrier to deliver the tracer agent carbon dots (CDs) and the “drug” thymolphthalein (TP), which was referred to as a “sense-and-treat” ELISA. In the “sense” part, the strong fluorescence intensity of CDs could be observed directly to achieve the sensitive detection of the target. In the “treat” part, after stimulation of alkaline solution, TP was released from ZIF-8 carriers and generated a color change with an obvious absorption, which was beneficial for increasing the sensitivity of this ELISA due to the high loading of the TP. Finally, we took carcinoembryonic antigen (CEA) as a model and performed dual-modal detection using this improved “sense-and-treat” ELISA to accomplish quantitative determinations sensitively and accurately. In addition, the results indicated by the two parts kept good concordance, which could demonstrate the reliable accuracy of this ELISA.
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APPLIED ORGANOMETALLIC CHEMISTRY
·
2019
·Vol. 33
·期 10
·e5145
·
IF 3.259
Zhiguo Lv,Shuying Zhang,Zhenmei Guo,Xi Cheng,Jiaomei Wang,Chao Zhang
The synthesis of alcohol ester 12 is one of the valuable industrial processes, but it was impeded by poor separating property and recycling ability of the catalytic systems. Herein, four novel DBU-based basic ionic liquids (DBILs) of [BDBU]IM, [BDBU]OH, [ODBU]IM, [[ODBU]OH were synthesized successfully by introducing the alkyl chains of 1-bromobutane or 1-bromooctane to 1,8-diazabicyclo [5.4.0] undec-7-ene (DBU), and then, employing imidazole (IM − ) or hydroxide (OH − ) as counter ions. The above obtained four ionic liquids were applied in the synthesis of alcohol ester 12 in isobutyraldehyde (IBD)/aqueous media for the first time. Interestingly, after reaction, production of alcohol ester 12 can be self-separated from ionic liquids/water (ILs/W) catalytic system automatically. Furthermore, the self-separated ILs/W can be recycled and used in next catalytic reaction for at least 5 times without obvious loss of catalytic performance. In this work, the structure, purity, thermal stability and alkalinity of DBILs were characterized systematically. [BDBU]IM shows high alkalinity and thus enhances yield of 66.17%. From thermo gravimetric analyzer (TGA), [BDBU]IM also exhibits excellent thermal stability. So [BDBU]IM was chosen for the further studying. Furthermore, quantum chemistry is applied to calculate the interaction forces and electron energies of reactants by DFT, and the calculation results illustrate the feasibility of synthetic process of DBILs. The self-separation strategy of DBILS in this work may open up a new avenue for the clean synthesis of other industrial products.
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