Nano Today
·
2025
·
IF 10.9
Majid Sharifi,Majid Salehi,Somayeh Ebrahimi-Barough,Mohammad Kamalabadi-Farahani
Neuroma formation following the repair of nerve injuries exceeding 0.9 cm in length severely impedes functional recovery. To overcome this challenge, we engineered magnetically responsive core-shell nanoparticles (MnFe 2 O 4 @ZIF-8@Retinoic acid, MFZR; 90–360 nm) to guide regeneration within a decellularized umbilical cord artery (DUCA) conduit. We investigated the synergistic effect of MFZR under an external magnetic field (MF) on Schwann cell behavior in vitro and on sciatic nerve repair in a rat model. Under MF exposure, MFZR significantly enhanced Schwann cell migration, alignment, and elongation on DUCA conduits. In-vivo , the MFZR+MF combination potently promoted functional recovery, as measured by the sciatic functional index, muscle compound action potential, and nerve conduction velocity, without inducing DUCA-related inflammation. Histological analysis demonstrated robust regeneration, characterized by increased axon diameter, an improved G-ratio, and elevated expression of S100 and NF-200. This regeneration was facilitated by a healing-promoting M2 macrophage polarization at the injury site. Critically, the strategy exhibited no systemic toxicity. These findings establish that magnetically guided MFZR effectively prevents neuroma in the DUCA conduits, orchestrates a pro-regenerative microenvironment, and achieves significant functional recovery, offering a promising translatable strategy for nerve repair.
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JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Tao Jian,Yongjin Fang,Xiang Cai,Mingyi Ying,Bisheng Li,Wangyang Ye,Liguo Shen,Leihong Zhao,Hongjun Lin
The development of high-performance membranes for heavy metal remediation remains a key challenge in advanced water treatment. In this work, a hierarchically structured composite membrane was fabricated via a self-confined growth strategy, in which Zn(OH) 2 nanostrands immobilized MoS 2 and directed the in-situ growth of ZIF-8, forming a defect-free interlayer for robust polyamide (PA) deposition. The resulting ZM15-PA membrane exhibits a highly hydrophilic surface with a contact angle of 31.5°, a strong positive surface charge under acidic conditions, and excellent water permeability reaching 83.5 L m -2 h -1 . Most notably, the membrane achieves an ultrahigh Pb(II) rejection rate of 99.2%, consistently reducing effluent concentrations to less than 10 μg L -1 , even in the presence of coexisting ions and dissolved organic matter. Mechanistic investigations reveal that Pb(II) removal is governed by synergistic mechanisms including electrostatic repulsion, molecular sieving, and coordination interactions involving Pb-S, Pb-O, and Pb-N bonds. Furthermore, the membrane demonstrates outstanding antifouling resistance, long-term operational stability, and antibacterial efficiency exceeding 99% under photo-Fenton conditions. These findings highlight the promise of self-confined growth strategies for stabilizing two-dimensional materials and developing multifunctional membranes for selective heavy metal removal in complex water matrices.
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高影响因子
CARBON
·
2025
·
IF 11.6
Zhongkai Zhao,Xiaobo Zhu,Jiaxi Li,Wenjing Wang,Xiaocheng Jiang,Shan Shi,Siming Ren
Intrinsic self-healing coatings have attracted considerable research interest due to their remarkable ability to repair damage autonomously. However, their insufficient impermeability limits their long-term application in metal corrosion protection. Herein, we embedded corrosion-inhibiting cerium-doped ZIF-8 nanoparticles (Ce@ZIF-8) modified graphene oxide (GO) two-dimensional sheets into an epoxy network containing dynamic hydrogen bonds and disulfide bonds, developing a room-temperature self-healing epoxy/GO-Ce@ZIF-8 composite with remarkable barrier and corrosion resistance properties. Due to the metal coordination interaction between zinc or cerium in GO-Ce@ZIF-8 and the epoxy dynamic network, the modified nanosheets are efficiently and stably dispersed in the epoxy resin. The elaborately designed composite exhibits excellent stretchability (424.95 %), exceptional room-temperature self-healing capabilities (80.7 % at 25 °C for 8 h), and outstanding corrosion resistance. This is ascribed to the synergy of the superior physical shielding effect of nanosheets and the passivation of cerium elements released from nanoparticles on metal surfaces, achieving active/passive long-term corrosion protection through the intrinsic self-healing and external passivation of composite. This innovative strategy provides a new approach to developing novel high-barrier self-healing materials.
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RENEWABLE ENERGY
·
2024
·
IF 9
Wenli Zhang,Jifei Liu,Hongwei Gu,Cheng Pan,Yifei Long,Qunpeng Cheng,Guozhi Fan
The metal-organic framework materials ZIF-8 and UiO-66-NH 2 , synthesized by hydrothermal methods, were characterized in detail and combined to catalyze the transfer hydrogenation of 5-hydroxymethylfurfural (5-HMF) to 2,5-di(hydroxymethyl)furan (2,5-DHMF) using isopropanol as the hydrogen source. The ZIF-8/UiO-66-NH 2 catalyst mixture exhibited abundant Lewis acid-base sites and a hierarchical multiporous structure with a large specific surface area (564.0 m 2 /g). The conversion of 5-HMF reached 98.2 %, and the selectivity and yield of 2,5-DHMF were 96.2 % and 94.5 %, respectively. The recycling performance of ZIF-8/UiO-66-NH 2 was also investigated, and the conversion of 5-HMF and selectivity of 2,5-DHMF significantly decreased to 78.4 % and 79.1 % in the second run, respectively. The loss of −NH 2 groups was found to be the main reason for the decrease in activity. However, the catalytic activity of the recovered catalyst can be almost completely restored by the addition of a small amount of fresh UiO-66-NH 2 and ZIF-8, and the conversion of 5-HMF and selectivity of 2,5-DHMF were increased to 89.4 % and 95.5 %, respectively. In the proposed reaction mechanism, Lewis acid-base sites play important roles and exhibit a synergistic catalytic effect in the selective conversion of 5-HMF to 2,5-DHMF.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Zhiqiang Guo,Juanjuan Meng,Xinxin Li,Xinlong Wang,Yuan Li,Liangliang Hu
Layered double hydroxides (LDHs), despite their unique layered structure advantageous for removing high-molecular-weight antibiotics, suffer from limitations such as small specific surface area, uncontrollable morphology, and irregular spatial structure compared to metal–organic frameworks (MOFs). Therefore, in this study, ZIF-8 was used as a template to prepare LDHs with a hollow mesoporous structure (ZNF-HS), merging the benefits of both materials. ZNF-HS was then stably incorporated into sodium carboxymethylcellulose aerogels, resulting in ZNF-HS@CMC composites that facilitated easy solid–liquid separation and were effective in removing tetracycline (TC) and ciprofloxacin (CIP) from aqueous solution. Characterization of ZNF-HS@CMC was conducted using SEM, TEM, XRD, FTIR, XPS, BET, and TGA. ZNF-HS@CMC exhibited a specific surface area of 248.753 m 2 ·g −1 and a pore volume of 0.568 cm 3 ·g −1 , surpassing traditional LDHs. The removal of TC and CIP by ZNF-HS@CMC followed the pseudo-second-order kinetic and Langmuir models, with maximum sorption capacities of 513.772 and 442.515 mg·g −1 , respectively. pH significantly influenced the removal efficiencies, while NaNO 3 concentration up to 0.25 mol·L −1 had negligible impact, maintaining removal efficiencies above 90 %. After five sorption–desorption cycles, the removal efficiencies remained above 80 %. The removal of TC and CIP by ZNF-HS@CMC was primarily achieved through surface complexation, hydrogen bonding, and π-π interactions, with electrostatic interactions also contributing. Overall, ZNF-HS@CMC exhibits the advantages of easy recycling, good reusability, strong resistance to salt interference, and high sorption capacity, making it promising for practical applications in the efficient removal of antibiotics from water.
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ELECTROCHIMICA ACTA
·
2025
·
IF 5.6
Junchun Guo,Li Xu,Lian Ou,Jinmi Zhang,Jianlong Li,Hongmei Huang,Xiaoli Xiong
As a persistent industrial pollutant, the accurate detection of nitrobenzene (NB) holds critical importance in environmental monitoring and health risk mitigation. Recently, the strategy of using metal-organic frameworks (MOFs) as self-sacrificial precursors/templates to design electrocatalysts with unique structures and excellent electrochemical sensing properties has been regarded as a promising approach. Herein, using ZIF-8 supported on hollow carbon spheres as a self-sacrificing model, a hierarchical electrocatalyst (N HCS@HSC) with a dual - hollow carbon nanostructure composed of N-doped hollow carbon spheres (N HCS) and fishnet-like nanonesh (HSC) was prepared. Benefiting from the interconnected hollow channels in the carbon nanomesh, accelerated electron transfer is achieved, with N-doping further engineering the catalyst's local charge density to optimize active sites. The micro-mesoporous ZIF-8-derived carbon is not only beneficial to the selective recognition of NB, but also enhances the electrically conductive of the catalyst and greatly alleviates the aggregation of active sites. The N HCS@HSC sensing platform demonstrates a broad dynamic response range (0.3–254 μM) with a low detection threshold (0.042 μM) toward NB, coupled with remarkable selectivity and long-term operational stability, which has important implications for human health and environmental safety.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Yixin Pan,Bo Sun,Yingying Zhou,Jian Jiao,Liping Deng,Xiaowu Dong
This study reported a Ni 0 @ZIF-8 nanocomposite synthesized via co-precipitation that synergistically integrated the high adsorption capacity of ZIF-8 with the redox activity of zero-valent nickel (Ni 0 ) for efficient uranium(VI) extraction. The composite with an optimized 1:1 ZIF-8:Ni 0 molar ratio achieved an exceptional adsorption capacity of 830.5 mg/g. Kinetic and thermodynamic analyses confirmed chemisorption-dominated monolayer adsorption following pseudo-second-order kinetics (R 2 > 0.999) and spontaneous endothermic behavior. Mechanistic investigations through spectroscopy and density functional theory (DFT) calculations revealed a dual-function mechanism that ZIF-8 facilitated U(VI) capture through electrostatic/coordination interactions, while Ni 0 mediated partial reduction of U(VI) to U(IV) via electron transfer, enhancing immobilization stability. Notably, only Pb 2+ , Cu 2+ , Cr 6+ , and organic ligands inhibited adsorption through redox competition and solution complexation. Comparative studies demonstrated minimal matrix interference-deionized water versus seawater systems exhibit merely 4.7 % deviation in adsorption efficiency at trace U(VI) concentrations (0.1–0.6 mg/L). Critically, direct uranium extraction from unprocessed natural seawater (ambient U: 4.27 μg/L) with only pH adjustment (5.0) achieves 86.02 % efficiency at ultra-low adsorbent dosage (0.001 g/L), yielding residual uranium concentrations of 0.597 ± 0.04 μg/L. By harmonizing adsorption and redox pathways, Ni 0 @ZIF-8 overcome limitations of conventional materials, establishing itself as a paradigm-shifting solution for uranium remediation in complex ionic matrices and real marine environments.
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高影响因子
International Journal of Electrochemical Science
·
2024
·
IF 1.3
Shuai Gao,Hongkun Long,Weigang Liu,Zhi Zhang,Shengqiang Qiu,Maoyi Yi,Jie Li
Poor safety of liquid electrolytes and low ionic conductivity of solid electrolytes under room temperature are two major constraints for high energy density, long-term stability and safety of lithium-ion batteries (LIBs). In order to remedy the deficiencies, a quasi-solid electrolyte (QSE) is developed by immobilizing liquid electrolyte into the host of porous 2-Methylimidazole zinc salt (ZIF-8), and then mixing them with solid polymer electrolyte solvent of polyoxyethylene (PEO). The QSE has an ionic conductivity of 0.44 mS cm −1 at 20 °C and 2.27 mS cm −1 at 50 °C. The assembled LiFePO 4 /QSE/Li batteries exhibit excellent electrochemical performance in a wide temperature range. A reversible capacity of 129.7 mAh g −1 at 0.5 C and 20 °C and high capacity retentation of 94.7% at 0.5 C and 50 °C are achieved after 100 cycles. Especially, the LiFePO 4 /QSE/graphite pouch full cell exhibits a capacity retention of 97.7% at 0.5 C and 25 °C. These results indicate that QSE is a suitable candidate for enhancing the electrochemical performance of LIBs.
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Desalination and Water Treatment
·
2024
·
IF 1
Gongduan Fan,Jing Luo,Israel de Jesus Lopez Prieto,Rujing Lin,Xiaomei Zheng,Liang Hong
The synthesis conditions of zeolitic imidazolate framework-8 (ZIF-8) have been optimized by a response surface method using central composite design (CCD) to obtain the high adsorption capability for the Pb(II) removal in aqueous solution. The physic-chemical properties of the as-prepared ZIF-8, such as morphology, structure and chemical composition, were characterized by field emission scanning electron microscopy (FE-SEM), powder X-ray diffraction (XRD) and energy-dispersive X-ray photoelectron spectroscopy (XPS), respectively. The adsorption capability, influence factors, isotherms, thermodynamics, kinetics and mechanism of Pb(II) in aqueous solutions were investigated. The optimal parameters of which have the highest adsorption capability for Pb(II) were 200 mL of water as the solvent, and the molar mass ratio of 2-methylimidazole and Zn(NO 3 ) 2 ·6H 2 O was 45.63. At this condition, the as-prepared ZIF-8 was a pure hexagonal three-dimensional crystal structure. The equilibrium adsorption capacity up to 668 mg/g for 300 mg/L of initial Pb(II) solutions and the adsorption was a spontaneous process. The largest adsorption capacity from Langmuir isotherm model was 686.25 mg/g. The adsorption kinetics followed the pseudo-second-order model. The equilibrium adsorption time and the optimal adsorption pH was 4 h and 6.0–7.0, respectively. The ZIF-8 still kept well adsorption effect after three times of usage. Therefore, this study showed that ZIF-8 is a promising sorbent for removing environmental pollutants.
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高影响因子
CRYSTAL GROWTH & DESIGN
·
2026
·Vol. 26
·期 15
·5988-6000
·
IF 3.6
Zhang Ge,Deng Lihan,Li Jin
Formaldehyde, a common indoor air pollutant, poses a
serious threat
to human health. Therefore, there is an urgent need to develop highly
selective and sensitive formaldehyde gas sensors that operate at room
temperature. Doping with rare-earth elements is an effectively proven
strategy for optimizing the gas-sensing performance at room temperature.
This study developed a method to modify ZnO derived from ZIF-8 by
doping it with the rare-earth element cerium (Ce). The Ce-doped ZnO
(ZCO) series of sensors inherit the shell-and-core architecture derived
from the ZIF-8 precursor, featuring a high specific surface area that
provides support for gas-sensing reactions. Additionally, Ce doping
induces the formation of more oxygen vacancies, thereby enhancing
the formaldehyde adsorption. Among these, the ZCO-2 gas sensor exhibits
the best formaldehyde sensing properties at room temperature, with
a responsiveness of 1006 for 500 ppm formaldehyde (77.4 times that
of a pure ZnO gas sensor) and a response/recovery time of 9/3 s. Because
of the high response value, fast response/recovery time, excellent
selectivity, repeatability, and stability of this gas sensor, it has
a very promising prospect in practical applications.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Yi-Fei Hui,Duan-Ping Hu,Yi Zhao,Shulin Li,Zhi-Feng Cai,Lin-Yi Li,Yuming Xie,Yong-Nian Zeng,Zu-Jin Lin,Fa-Qiang Tang
Sacrificial template strategy builds ZnO 2 @Hemin-ZIF-8 core-shell structure. • The seamless ZIF-8 shell prevents premature ZnO 2 leakage at physiological pH. • Hierarchical ZnO 2 @Hemin-ZIF-8@PB (ZHZHP) enables on-demand H 2 O 2 release. • ZHZHP enables dual-nanozyme cascade-based CDT and PTT to eradicate bacteria. • ZHZHP orchestrates anti-inflammation and angiogenesis to accelerate wound healing. Chemodynamic therapy (CDT) has emerged as a promising strategy for combating bacterial infections; however, the scarcity of endogenous H 2 O 2 within infection sites often bottlenecks therapeutic efficacy. Herein, a pH-responsive, H 2 O 2 self-supplying nanoplatform is meticulously engineered for spatiotemporally controlled chemodynamic–photothermal antibacterial therapy. This platform leverages ZnO 2 nanoparticles dual-role cores and sacrificial template to drive the in situ epitaxial growth of dense ZIF-8 shells (optionally encapsulated with Hemin), yielding the core–shell ZnO 2 @ZIF-8 (or ZnO 2 @Hemin-ZIF-8) intermediate. Stepwise surface engineering with hyaluronic acid (HA) and Prussian blue (PB) leads to the formation of a hierarchical core–shell structured ZnO 2 @Hemin-ZIF-8@HA@PB nanoplatform (ZHZHP). Under neutral physiological conditions, ZHZHP exhibits excellent stability as the interracially-bonded ZIF-8 shell effectively shields the ZnO 2 core from premature hydrolysis. Conversely, within the weakly acidic infection microenvironment, ZHZHP undergoes programmed disassembly, triggering the on-demand release of H 2 O 2 . Simultaneously, Hemin and PB act as peroxidase mimics to catalyze the conversion of liberated H 2 O 2 into highly toxic hydroxyl radicals (‧OH) via dual nanozyme cascades, while the PB component provides robust photothermal conversion under 808 nm NIR irradiation. This synergistic CDT/PTT approach achieves complete eradication of S. aureus and E. coli at an extremely low concentration of 50 μg mL −1 and demonstrates remarkable efficacy in disrupting both immature and mature biofilms. In vivo assays further confirm that ZHZHP significantly accelerates infected wound healing through potent antimicrobial and anti-inflammatory activities, alongside the promotion of angiogenesis. With high biocompatibility and negligible toxicity, ZHZHP represents a sophisticated strategy for the clinical management of refractory wound infections. Download: Download high-res image (156KB) Download: Download full-size image
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FOOD CHEMISTRY
·
2026
·
IF 10.4
Xiao-Yi Tong,Yun-Feng Liu,Zhi-Hong Xu,Wan Li,Long-Fei Li,Li Han,Li-Juan Wang,Hong-De An,Fei Cao
Postharvest apple ring rot caused by Botryosphaeria dothidea remains difficult to control due to the poor aqueous compatibility and rapid volatilization of volatile essential oils. We engineered a chitosan (CS) film embedding Ligusticum jeholense essential oil within zeolitic imidazolate framework-8 (LEO@ZIF-8) to achieve sustained antifungal release. TEM/SEM, FT-IR, XRD, and XPS confirmed high LEO loading (65.5%) and encapsulation efficiency. LEO@ZIF-8 demonstrated pH-responsive release, with 82.6% at pH 5.0. In vitro, LEO@ZIF-8 inhibited B. dothidea more effectively than free LEO (64.6% vs. 50.6% at 62.5 nL/mL). On detached apples, LEO@ZIF-8/CS film improved hydrophobicity, enhanced microstructural homogeneity, and delayed lesion formation. It reduced weight and firmness loss, retained soluble solids, and decreased oxidative stress markers (DPPH, SOD, MDA). ZIF-8 stabilized LEO and enabled controlled release, while CS provided antimicrobial support, demonstrating LEO@ZIF-8/CS as an effective active-packaging solution for long-term fruit preservation, offering a sustainable approach to postharvest disease control.
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PubMed
高影响因子
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