JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2023
·
IF 2.6
Lingli Zhang,Chunjuan Huang
The solubility of 2-amino-5-bromopyrazine in the co-solvent mixtures of methanol, ethanol, isopropanol, and propylene glycol (PG) plus water and 10 monosolvents (methanol, ethanol, isopropanol, N,N-dimethylformamide (DMF), n-propanol, n-butanol, acetone, ethylene glycol (EG), PG, and water) was experimentally measured by the isothermal method at 278.15–323.15 K under 101.2 kPa. The temperature dominated the trend of solubility of 2-amino-5-bromopyrazine in pure and mixed solvents, especially high temperatures had a positive effect on dissolution. For the pure solvent system, the maximum solubility was obtained in DMF. For the mixed systems, isopropanol + water was superior to the other three combinations. The Apelblat model, van’t Hoff model, and NRTL model were used to correlate the solubility of 2-amino-5-bromopyrazine in 10 monosolvents. Furthermore, three thermodynamic co-solvency models including the Jouyban–Acree (JA) model, the Van’t Hoff–Jouyban–Acree (VJA) model, and the modified Apelblat–Jouyban–Acree (AJA) model were used to calculate the solubility data. This study would be helpful to the synthesis and purification processes of the final product.
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高影响因子
ACS Omega
·
2021
·
IF 3.512
Longfei Gao,Huiyuan Luo,Qian Wang,Guirong Hu,Yuzhu Xiong
The hydrogel prepared by graft copolymerization of starch (ST) and acrylamide (AM) is a commonly used absorbent material; however, due to their irregular network structure and a limited number of hydrophilic groups, starch-based hydrogels have poor water absorption and water retention. To overcome this, here, we provide a new preparation method for starch-based hydrogels. Using cerium ammonium nitrate (CAN) as an initiator, the starch–acrylamide–cellulose (CMC)/poly(ethylene glycol) (S-A-M/PEG) superabsorbent hydrogel was prepared by graft copolymerization. The starch–acrylamide–cellulose/poly(ethylene glycol) hydrogel network is constructed through the synergistic effect of hydrogen bonds and chemical bonds. The experimental results showed that the starch–acrylamide–cellulose/poly(ethylene glycol) superabsorbent hydrogel has a complete network structure that does not easily collapse due to its superior mechanical properties. The water swelling rate reached 80.24 times, and it reached 50.61% water retention after 16 days. This hydrogel has excellent water-absorbing and water-retaining properties, biocompatibility, and degradability, making it useful for further studies in medical, agricultural, and other fields.
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高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2021
·
IF 3.764
Xin Gao,Yiwei Wang,Rui Wang,Chengna Dai,Biaohua Chen,Jiqin Zhu,Xingang Li,Hong Li,Zhigang Lei
1,2-Butene carbonate (BC) is an important five-membered cyclic carbonate with a high commercial value, but its massive production is limited by the lack of raw material 1,2-butanediol (1,2-BDO). 1,2-BDO is coproduced with ethylene glycol (EG) in the hydrogenation process in the coal-to-EG route, one-pot conversion of biomass to liquid fuels and chemicals, and fermentation of broths. However, the separation and purification of 1,2-BDO are difficult. In this paper, an intensified reactive distillation process for the separation of the EG and 1,2-BDO azeotropic mixture via dimethyl carbonate assisted chemical looping technology and coproduction of BC and EG products is proposed. The transesterification reactions of EG and 1,2-BDO were investigated individually in the presence of basic resin catalyst KIP321, and the kinetic parameters were imbedded into Aspen plus (V11) for the design of the reactive distillation column to perform the transesterification process. The proposed flowsheet, which includes the transesterification unit, a DMC and methanol separation unit, and an EG recovery unit, was designed and simulated. Remarkably, the conversions of diols are over 0.998, the yield of 1,2-butylene carbonate is 99.86%, and the yield of the EG product is theoretically 100%, which shows excellent potential for industrial application.
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ENERGY & FUELS
·
2023
·
IF 5.3
Hong Yao,Houfang Lu,Kejing Wu,Yingming Zhu,Binshen Wang,Yingying Liu,Yijiao Qiu,Bin Liang
Biphasic solvent 3-dimethylaminopropylamine (DMAPA)/poly(ethylene glycol) dimethyl ether (NHD)/H2O solution is a promising absorbent for CO2 capture. The kinetics of CO2 absorption in both DMAPA/NHD/H2O system and DMAPA/H2O systems was investigated and compared in a wetted wall column reactor with different CO2 loadings at different CO2 partial pressures from 30 to 70 °C. The equilibrium CO2 loadings were also determined. Meanwhile, the density and viscosity for both systems were measured. In both systems, the mass transfer flux of CO2 increases linearly with the increase of CO2 partial pressure. The kinetic data were interpreted by the zwitterion mechanism. The overall mass transfer constant was determined according to the absorption rate experiments performed in the pseudo-first-order regime. The overall mass transfer resistances increase with the increase of CO2 loading and decrease with the increase of temperature. The addition of NHD decreases the equilibrium CO2 loadings at the same CO2 partial pressure and temperature. However, it increases the enhancement factor significantly and can promote both the absorption and the desorption process. It provides basic information not only for the further utilization of DMAPA/NHD/H2O solution, which is helpful for the design of absorption reactor, but also for developing new phase-change absorbents for CO2 capture.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2023
·
IF 7.2
Xinkuai He,Zhousi Hu,Jingjing Yang,Ruqing Guo,Luye Wu
The co-deposition behavior of Co(II) and Mo(VI) in N,N-dimethylformamide and ethylene glycol system is observed. The result implies that Co–Mo co-deposition is typical induced deposition, while containing ordinary deposition process . Mo(VI) species in the system can suppress the reduction of Co(II) and its effect can be improved as the increase of Mo(VI) concentration, however, Co(II) species can promote the reduction of Mo(VI) and the effect can also be improved as the increase of Co(II) concentration. SEM micrographs indicate that all these films exhibit a fibrous surface morphology with a new fluffy microstructure. XRD pattern reveals that the Co–Mo film is a Mo solid solution in Co and its average size of crystalline grain is 9.5 nm. In addition, the electrocatalytic activity for hydrogen evolution reaction (HER) on these Co–Mo films is investigated. These results indicate that its electrocatalytic activity can be improved as Mo content increases from 1.02 to 2.84 wt% and the prepared Co–Mo film with 2.84 wt% Mo presents a high electrocatalytic activity and stability for HER with an overpotential of 81 mV at 10 mA cm −2 .
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BIOMEDICINE & PHARMACOTHERAPY
·
2019
·
IF 3.743
Zhongchao Wang,Ying Yan,Yini Wang,Fei Tong
Introduction The purpose of the experiment was to survey the therapeutic function of resveratrol (RES)-loaded poly(ethylene glycol)-poly(phenylalanine) (PEG-PPhe) on intestinal ischemia/reperfusion injury (II/RI) via the interaction between CSE/H 2 S and iNOS/NO compared to free RES in diabetic rats. Methods Diabetic rats were pretreated with 20 mg/kg of RES or the RES/PEG-PPhe complex and then subjected to 1 h of ischemia and 3 h of reperfusion. Blood and intestines were collected, intestinal pathological injury was estimated, and the contents of body weight, weights of different tissues, blood glucose, serum insulin, HOMA index, serum nitric oxide (NO) and serum sulfureted hydrogen (H 2 S) were observed. The dry/wet intestine ratios, the activity of superoxide dismutase (SOD); the contents of methane dicarboxylic aldehyde (MDA), glutathione (GSH), H 2 S, and NO; and the concentrations of inducible nitric oxide synthase (iNOS) and cystathionine-γ-lyase (CSE) were observed in the intestinal tissues. Results A significant reduction of weights of different tissues, blood glucose, pathological damage, dry/wet ratios, MDA, NO, iNOS expression and a significant increasement of body weight, serum insulin, HOMA index, SOD, GSH, H 2 S, CSE expression were observed in both treatment groups. However, a greater reduction of weights of different tissues, blood glucose (7.49–13.49 mmol/L for 72 h vs. the control) and pathological damage, iNOS expression, dry/wet ratios (6.14 ± 0.29 vs. 8.51 ± 0.42), MDA (5.01 ± 0.71 nmol vs. 9.98 ± 0.67 nmol), NO (0.52 ± 0.09 μmol vs. 0.99 ± 0.08 μmol in intestinal tissue; 19.29 ± 0.89 μmol vs. 45.23 ± 1.17 μmol in serum) was observed in the RES/PEG-PPhe group relative to the I/R ( P < 0.01 for all); a greater increasement of body weight, serum insulin, HOMA index, SOD (39.79±1.78 U vs. 11.84 ± 1.02 U), GSH (31.25 ± 1.19 mg vs. 10.13 ± 0.64 mg), H 2 S (39.52 ± 1.32 nmol vs. 13.02 ± 1.03 nmol in intestinal tissue; 9.78 ± 0.79 μmol vs. 3.11 ± 0.85 μmol in serum), CSE expression was observed in the RES/PEG-PPhe group relative to the I/R ( P < 0.01 for all). In addition, aminoguanidine (AMI, iNOS inhibitor) reduced I/R injury, and dl -propargylglycine (PAG, CSE inhibitor) increased I/R injury. Conclusions The interaction between CSE/H2S and the iNOS/NO-mediated resveratrol/poly(ethylene glycol)-poly(phenylalanine) complex alleviates intestinal ischemia/reperfusion injuries in diabetic rats.
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高影响因子
Frontiers in Pharmacology
·
2018
·
IF 3.831
Tsai Hsiang-I,Jiang Lijuan,Zeng Xiaowei,Chen Hongbo,Li Zihuang,Cheng Wei,Zhang Jinxie,Pan Jie,Wan Dong,Gao Li,Xie Zhenhua,Huang Laiqiang,Mei Lin,Liu Gan
The clinical applications of platinum-based antitumor agents are still largely limited by severe side effects as well as multidrug resistance (MDR). To solve these problems, we developed an 1,2-diaminocyclohexane-platinum(II) (DACHPt)-loaded nanoparticle (NP-TPGS-Pt) by self-assembly of poly(amidoamine)-polyglutamic acid-b-D-α-tocopheryl polyethylene glycol 1000 succinate (PAM-PGlu-b-TPGS) and DACHPt. NP-TPGS-Pt showed robust stability and pH-responsive DACHPt release profile in vitro similar to the PEG-containing nanoparticle (NP-PEG-Pt). Meanwhile, in contrast with NP-PEG-Pt, NP-TPGS-Pt exhibited efficient nanoparticle-based cellular uptake by the Pt-resistant A549/DDP human lung cancer cells and caused much more cytotoxicity than free Oxaliplatin and NP-PEG-Pt. Finally, this NP-TPGS-Pt was proved to perform outstanding inhibition of Pt-resistant tumor growth, much superior than free Oxaliplatin and NP-PEG-Pt. Thus, this NP-TPGS-Pt provides a novel powerful nanomedicine platform for combatting multidrug resistant cancer.
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高影响因子
JOURNAL OF POLYMER RESEARCH
·
2012
·Vol. 19
·期 4
·1-7
·
IF 1.733
Li Ming,Ren Wentan,Zhang Yong,Zhang Yinxi
A novel kind of gel polymer electrolytes (GPE) based on comb-like copolymers of poly(ethylene glycol) monomethylether (mPEG) grafted carboxylated butadiene-acrylonitrile rubber (XNBR) were prepared by introducing ionic liquids and LiClO 4 into polymer framework. FTIR spectra confirmed the grafting of mPEG to XNBR as side chains, and the content of grafted mPEG were calculated from the integral area of related peaks in 1 H NMR spectra. Such grafted copolymer based GPE with ionic liquids as solvent showed higher ionic conductivity and reached a maximum ionic conductivity of 1.64 × 10 −3 S/cm (30 °C) in the experimental range, because the copolymers performed better polymer chain flexibility, which could be concluded from the decrease of T
g and crystallinity through DSC analysis. The generated GPE exhibited high electrochemical stability and the unit cell of LiFePO 4 /GPE/Li could be cycled at room temperature.
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高影响因子
JOURNAL OF POWER SOURCES
·
2016
·
IF 6.333
Yunyun Zhai,Ke Xiao,Jianyong Yu,Bin Ding
The x-polyethylene glycol diacrylate (x-PEGDA) coated polyetherimide/polyvinylidene fluoride (PEI/PVdF) membranes are obtained by the facile combination of dip-coating and free radical polymerization of PEGDA on the electrospun PEI/PVdF fiber membranes. Successful cross-linking of PEGDA increases the average fibers diameter from 553 to 817 nm and reduces the packing density, which not only increases the tensile strength of x-PEGDA coated PEI/PVdF membranes, but also decreases the average pore diameter . Besides, the x-PEGDA coated PEI/PVdF membranes are endowed with good wettability , high electrolyte uptake, high ionic conductivity and improved electrochemical stability window because of the good affinity of PEI and PEGDA with liquid electrolyte . Benefiting from the synergetic effect of PEI and PVdF, the x-PEGDA coated PEI/PVdF membranes exhibit excellent thermal stability and nonflammability, which are beneficial for enhancing the safety of lithium ion batteries . More importantly, the x-PEGDA coated PEI/PVdF membranes based Li/LiFePO 4 cell exhibits comparable cycling stability with capacity retention of 95.9% after 70 cycles and better rate capability compared with the Celgard membrane based cell. The results clearly demonstrate that the x-PEGDA coated PEI/PVdF membranes are the promising separator candidate with improved wettability and safety for next-generation lithium ion batteries.
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MICROCHIMICA ACTA
·
2017
·Vol. 184
·期 10
·4133-4140
·
IF 4.58
Xu Kaijia,Wang Yuzhi,Zhang Hongmei,Yang Qin,Wei Xiaoxiao,Xu Panli,Zhou Yigang
A magnetically responsive composite was prepared for improved solid-phase extraction of salmon sperm DNA sodium salt. It consists of chitosan-modified Fe 3 O 4 -magnetized multi-walled carbon nanotubes coated with a poly(ethylene glycol) based deep eutectic solvent. The sorbent was characterized by X-ray diffraction, vibrating sample magnetometry, Fourier transform infrared spectrometry, thermogravimetric analysis and transmission electron microscopy. The effects of the concentration of DNA, ionic strength, pH value, temperature and extraction time on extraction performance were optimized. Compared to plain Fe 3 O 4 , the new sorbent displays a superior DNA extraction capacity of 178 mg·g −1 . It also displays favorable selectivity for DNA over bovine hemoglobin. Regeneration studies show that (a) 79% of DNA can be eluted from loaded sorbent by using 1 M NaCl, and that (b) the conformation of DNA remains unchanged as evidenced by CD spectra. The sorbent can be recycled six times without significant loss of extraction capacity. It was applied to the extraction of DNA from bovine whole blood prior to DNA quantitation by agarose gel electrophoresis. The results show this new sorbent to be a viable material for separation of DNA that excels by its low cost, high loading capacity and ease of regeneration.
Chitosan (CS)-modified magnetic multi-walled carbon nanotubes were coated with a poly(ethylene glycol)-based deep eutectic solvent (DES) to obtain a new material (referred to as DES-mCS/MWCNTs) for solid-phase extraction of DNA. It exhibits excellent magnetic response, high loading capacity and good reusability.
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EUROPEAN POLYMER JOURNAL
·
2017
·
IF 3.531
Le Li,Zhi-Qiang Cao,Rui-Ying Bao,Bang-Hu Xie,Ming-Bo Yang,Wei Yang
Different from traditional small molecular plasticizers, poly( l -lactic acid) (PLLA)-polyethylene glycol (PEG)-PLLA triblock copolymers were synthesized by ring-opening polymerization of L-lactide on the end hydroxyls of PEG and blended with PLLA, to enhance the crystallization of PLLA. Non-isothermal and isothermal crystallization studies show that the triblock copolymer enhances the crystallization of PLLA due to the nucleation effect from PLLA segments and the plasticization effect from PEG segments, which strongly depends on the structure of copolymers. With shorter PLLA segment and longer PEG segment of the triblock copolymer, the glass transition temperature and cold crystallization temperature of the blends decrease, and the degree of crystallinity and spherulite growth rate increase owing to the higher content of PEG. However, triblock copolymers with relatively longer PLLA segment and shorter PEG segment show unique nucleation effects for PLLA, leading to the elevation of crystallization temperature of PLLA. The results confirm that the crystallization acceleration of PLLA can be ascribed to the nucleation and plasticization effect, and the plasticization effect is more significant. What’s more, the introduction of triblock copolymers improves the compatibility and durability due to the good interfacial interaction with PLLA matrix even at a high loading.
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高影响因子
Arabian Journal of Chemistry
·
2017
·
IF 4.553
Changchang Zhang,Yong Kuai,Heming Cheng,Xiang Liu,Liang Ma
A technique of covalent bonding of grafted polymer brushes of poly(poly(ethylene glycol) monomethacrylate) (P(PEGMA)) on the surface of silicon quantum dots (SiQDs) and activation of the end hydroxyls with N-hydroxysuccinimide (NHS) esters were described in this work in detail. Firstly, a Si/SiQDs slice was disposed with hydrofluoric acid solution to produce surface Si-H x ( x = 1, 2 or 3) species, which combined with vinyl group of 1-undecenol covalently gives terminal hydroxyls. Such hydroxyls were initialized and were involved in atom transfer radical polymerization to construct grafted polymer brushes of P(PEGMA). Hence the density of the surface hydroxyls was enhanced extremely on account of the end hydroxyls of the side chains of the polymer brushes. Then carboxyl groups were introduced via terminal esterification with succinic anhydride, which were activated subsequently with NHS giving NHS esters under rather mild conditions. The reactivity of the terminal NHS esters was demonstrated by SDS-PAGE gel electrophoresis and fluorescence imaging. The SiQDs were demonstrated by transmission electron microscopy. The stepwise modifications on SiQDs were characterized by infrared and X-ray photoelectron spectra. The photoluminescence of the SiQDs was remained during the chemical modifications, proved by the measurements of fluorescence spectra.
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