JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 55
·期 31
·15263-15274
·
IF 3.553
Wang Jie,Li Zhifeng,Yin Yamin,Liu Haisha,Tang Guohua,Ma Yanxia,Feng Xin,Mei Han,Bi Jinlian,Wang Ke,Chen Zuanguang
Abstract The construction of effective and safe theranostics was very important to realize tumor diagnosis and treatment simultaneously. Photothermal therapy had obtained great attention due to its remarkable capability of both cancer treatment and biosecurity. Molybdenum disulfide (MoS 2 ) nanoflakes have shown excellent photothermal conversion efficiency, which were explored to photothermal therapy. However, MoS 2 nanoflakes would decrease or quench the intensity of fluorescence when the MoS 2 nanoflakes directly incorporated with fluorescence dyes to construct bioimaging theranostic systems. In this work, MoS 2 nanoflakes embedded into MSNs to construct photothermal nanomaterials, which realized the nanoparticle size controllable. Fluorescein isothiocyanate (FITC) conjugated with mesoporous silica nanoparticles via amide bonds for bioimaging. It was more stable than physical absorption. As expected, the as-prepared FITC–MoS 2 MSNs possessed photothermal effect, fluorescence stability and photostability. FITC–MoS 2 MSNs were quickly taken up by HepG2 cells. Meanwhile, the HepG2 cells could be efficiently ablated under the 808 nm near-infrared laser irradiation. These results proved that we successfully constructed multifunctional MSNs for tumor theranostics. It also provided a potentially common nanoplatform for theranostic of biomedical applications. Graphic abstract
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MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 9
·1-8
·
IF 6.232
Li Xiaoyun,Weng Chenyuan,Wang Jing,Yang Wei,Lu Qiaoyun,Yan Xiaoqiang,Sakran Marwan Ahmad,Hong Junli,Zhu Wanying,Zhou Xuemin
A novel label-free and exonuclease III (Exo III)–assisted signal amplification electrochemical aptasensor was constructed for the determination of carcinoembryonic antigen (CEA) via magnetic field–induced self-assembly of magnetic biocomposites (Fe 3 O 4 @Au NPs-S1-S2-S3). The magnetic biocomposites were acquired by modifying double-stranded DNA (S1-S2-S3) on the surface of Fe 3 O 4 @Au nanoparticles (Fe 3 O 4 @Au NPs). Among them, Fe 3 O 4 @Au NPs were used as carriers for magnetic separation, thiolated single-stranded DNA (S1) provided signal sequence, CEA aptamer (S2) worked as a recognition element, and complementary strand (S3) was used to form double strands. In the presence of CEA, S2 bonded with CEA competitively; the exposed S1 could not be cleaved since Exo III was inactive against ssDNA. The G-quadruplex/hemin complexes finally formed with the existence of K + , and the high electrochemical signal of G-quadruplex/hemin complexes was recorded by differential pulse voltammetry (DPV) at − 0.6 V. Conversely, in the absence of CEA, dsDNA was cleaved from the 3′ blunt end by Exo III; the disappearance of G-rich sequence blocked the generation of the signal. This method exhibited good selectivity and sensitivity for the determination of CEA; the linear range was from 0.1 to 200 ng mL −1 and the limit of detection was 0.4 pg mL −1 .
Graphical abstract
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Journal of Natural Medicines
·
2020
·Vol. 75
·期 1
·37-47
·
IF 2.055
Han Jieru,Shi Guangyu,Li Wenhao,Xie Ying,Li Fuzhen,Jiang Deyou
Monosodium urate (MSU)-mediated inflammation is closely related to gouty arthritis (GA). Dioscin, an active ingredient, has been reported to possess anti-inflammatory property. Nevertheless, the role of dioscin in GA and the underlying mechanism have not been fully understood. In the present study, we investigated the anti-inflammatory effect of dioscin on MSU-induced GA through in vivo and in vitro experiments. Histopathological analysis showed that dioscin alleviated the severity of GA concomitant with the lowered uric acid and creatinine levels. Moreover, the increasing IL-1β, IL-6, and TNF-α levels induced by MSU were decreased via administration of dioscin in mice and human synoviocytes. Western blotting results suggested that dioscin inhibited the activation of NLRP3 through down-regulating the protein expressions of NLRP3, apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), cleaved-caspase-1, as well as IL-1β. In addition, TLR4, myeloid differentiation primary response gene 88 (MyD88), p-IKKβ, p-p65, and NF-κB p65 in nuclei levels were significantly reduced by dioscin. Importantly, dioscin remarkably lowered the NF-κB p65-DNA activity in MSU-treated mice utilizing electrophoretic mobility shift assay (EMSA) analysis. Taken together, dioscin had a protective effect against MSU-initiated inflammatory response via repressing the production of inflammatory cytokines and the activation of inflammasome NLRP3 and TLR4/NF-κB signaling pathway. The above findings revealed that dioscin could be a potential drug for the treatment of GA.
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CATALYSIS LETTERS
·
2020
·Vol. 151
·期 3
·720-733
·
IF 2.482
Zhu Anlian,Li Qixing,Feng Wanlu,Fan Dongshuang,Li Lingjun
Abstract The synthesis of 2-amino-4H-chromenes through one-pot multicomponent reactions has received great attention due to the high atom efficiency and the broad bioactivities of the products. Here, the catalytic performances of a series of functional ionic liquids towards this type of reaction were investigated and the results showed that the ionic liquid, choline acetate ([Choline][Ac]), could efficiently promote this reactions under room temperature without the necessary of organic solvents. The reaction is easy to be conducted and the following work-up procedures are very simple. The pure products can be obtained through extraction and washing procedures, no column separation procedures are needed. Intriguingly, this reaction system can be easily scaled up to multi-gram, suggesting its perspective in industrial applications. In addition, the ionic liquid [Choline][Ac] can be easily prepared from cheap and biocompatible materials, and it can be feasibly recycled and reutilized for at least five cycles. Graphic Abstract
Various aldehydes, malononitrile and activated phenols could be converted to the
corresponding 2-amino-4H-chromenes with good to excellent isolated yields under
the catalysis of choline acetate at room temperature.
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Nature Communications
·
2020
·Vol. 11
·期 1
·1-8
·
IF 12.121
Wang Chenhui,Han Dengbao,Wang Junhui,Yang Yingguo,Liu Xinyue,Huang Sheng,Zhang Xin,Chang Shuai,Wu Kaifeng,Zhong Haizheng
In the field of perovskite light-emitting diodes (PeLEDs), the performance of blue emissive electroluminescence devices lags behind the other counterparts due to the lack of fabrication methodology. Herein, we demonstrate the in situ fabrication of CsPbClBr 2 nanocrystal films by using mixed ligands of 2-phenylethanamine bromide (PEABr) and 3,3-diphenylpropylamine bromide (DPPABr). PEABr dominates the formation of quasi-two-dimensional perovskites with small- n domains, while DPPABr induces the formation of large- n domains. Strong blue emission at 470 nm with a photoluminescence quantum yield up to 60% was obtained by mixing the two ligands due to the formation of a narrower quantum-well width distribution. Based on such films, efficient blue PeLEDs with a maximum external quantum efficiency of 8.8% were achieved at 473 nm. Furthermore, we illustrate that the use of dual-ligand with respective tendency of forming small- n and large- n domains is a versatile strategy to achieve narrow quantum-well width distribution for photoluminescence enhancement.
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Nano Research
·
2020
·Vol. 14
·期 7
·2301-2308
·
IF 8.183
Zhu Kunlei,Li Chenyu,Jiao Yushuang,Zhu Jiawen,Ren Hongtao,Luo Yufeng,Fan Shoushan,Liu Kai
The construction of advanced electrode materials is key to the field of energy storage. Herein, a free-standing anatase titania (TiO 2 ) nanocrystal/carbon nanotube (CNT) film is reported using a simple and scalable sol-gel method, followed by calcination. This unique free-standing film comprises ultra-small TiO 2 nanocrystals (∼ 5.9 nm) and super-aligned CNTs, with ultra-dispersed TiO 2 nanocrystals on the surfaces of the CNTs. On the one hand, these TiO 2 nanocrystals can significantly decrease the diffusion distance of the charges and on the other hand, the cross-linked CNTs can act as a three-dimensional (3D) conductive network, allowing the fast transport of electrons. In addition, the film is free-standing, without requiring electrode fabrication and additional conductive agents and binders. Owing to these above synergistic effects, the film is directly used as an anode in Li-ion batteries, and delivers a high discharge capacity of ∼ 105 mAh·g −1 at high rate of 60 C (1 C = 170 mA·g −1 ) and excellent cycling performance over 2,500 cycles at 30 C. These results indicate that the free-standing anatase TiO 2 nanocrystal/CNT film affords a superior performance among the various TiO 2 materials and can be a promising anode material for fast-charging Li-ion batteries. Moreover, the TiO 2 /CNT film exhibits an areal capacity of up to 2.4 mAh·cm −2 , confirming the possibility of its practical use.
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CELLULOSE
·
2020
·Vol. 27
·期 16
·9547-9558
·
IF 4.21
Xu Jianing,Tan Yunlong,Du Xiaosheng,Du Zongliang,Cheng Xu,Wang Haibo
The development of phase change materials (PCMs) with high energy storage density, enhanced photothermal conversion efficiency and good form-stability is essential for practical application in utilization of solar energy. Herein, novel PCM composites (CPPCMs) with extremely high energy storage density and superb solar-thermal conversion performance were fabricated by introducing n- octacosane into three-dimensional (3D) porous cellulose nanofibril (CNF)/polypyrrole (PPy) hybrid aerogels. Due to the strong encapsulation capability of CNF/PPy hybrid aerogels (CPAs), the synthesized PCM composites maintained perfect shape stability above the melting point of n- octacosane. Further investigation showed CPPCMs exhibited extremely high latent heat in the range of 239.4–258.4 J/g and high loading rate of n- octacosane (up to 96%). The melting/cooling cycling test and thermogravimetric analysis indicated the composite PCMs possessed excellent cyclic stability and thermal stability. Moreover, simulated sunlight test showed that the photothermal conversion efficiency of CPPCMs significantly improved with the increased content of polypyrrole in the PCM composites. In conclusion, the obtained PCM composites, which exhibited excellent shape stability, superior solar-heat conversion capability and extremely high energy storage density, showed considerable potential for practical utilization and storage of solar energy.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2020
·Vol. 36
·期 6
·1153-1160
·
IF 1.063
Wang Huanfeng,Li Junfeng,Li Fei,Li Jingjing,Xu Jijing
Highly stable and efficient bifunctional air cathode catalyst is crucial to rechargeable metal-air batteries. Herein, a ternary nanoalloy layer composed of noble and base metal coated on a three-dimensional porous Ni sponge as the bifunctional cathode is synthesized through in-situ anchoring strategy, which can effectively keep the multi-metal nanoparticles from agglomeration and improve the density of active sites and catalytic activity. The prepared catalyst displays an excellent catalytic performance with lower overpotential and long-term stability. The Zn-air batteries with the as-prepared cathodes possess a large power density of 170 mW/cm 2 , long cycling stability up to 230 cycles, and a high specific capacity of 771 mA·h/g. Furthermore, the corresponding Li-air batteries deliver a discharge capacity of 22429 mA·h/g. These superior properties of the metal-air batteries can be attributed to the combined influence of design and composition of electrode, which is of great significance to improve the electrochemical catalytic activity, providing great potential of wide application in expanded rechargeable energy systems.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2020
·Vol. 28
·期 3
·3465-3474
·
IF 3.056
Bai Maojuan,Xu Chengcheng,Huang Xuanye,Yin Han,Wan Jun
CuSe as an excellent photocatalytic semiconductor material has wildly used in the field of photocatalysis. In this paper, CuSe-PDA/g-C 3 N 4 was designed and synthesized, and the photocatalytic performance of CuSe was further enhanced by the addition of polydopamine (PDA) and graphite phase carbon nitride (g-C 3 N 4 ). The as-prepared CuSe-PDA/g-C 3 N 4 was characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray powder diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT-IR), and elemental mapping. The specific surface area and porous characteristics of the material were also studied by N 2 adsorption-desorption isotherm, which the specific surface area were 186.6 m 2 /g and pore size were of 3.1 nm by BET data analysis. The photocatalytic conditions for the degradation of methylene blue (MB) by CuSe-PDA/g-C 3 N 4 were optimized in the experiment. The results showed that the photocatalytic performance of CuSe-PDA/g-C 3 N 4 under visible-light illumination were better than CuSe and PDA owing to the narrow band gap energy and delayed electron-hole recombination. Under the optimized conditions, the removal rate reach to 99% of 50 mg/L MB within 60 min irradiation time. Moreover, the MB removal rate was over 90% through six repeated experiments, which proved that the CuSe-PDA/g-C 3 N 4 composite nanomaterials have good stability and reusability.
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JOM
·
2021
·Vol. 73
·期 6
·1631-1636
·
IF 2.474
Liu Fengguo,Liu Aimin,Hu Xianwei,Wang Zhaowen,Shi Zhongning
The conversion of CO 2 into carbon materials and oxygen gas has great significance for reducing the greenhouse gas concentrations of Earth and realizing in situ utilization of Mars’ atmosphere. In this work, LiF-Li 2 O melts containing CO 2 were electrolyzed using a Ni cathode and Pt anode at 850°C. Carbon materials with different morphologies were deposited on the cathode and oxygen evolution was detected in anode gas. The products were characterized by Raman spectroscopy, x-ray diffraction, scanning electron microscopy and gas chromatography. The results demonstrated that CO 2 was firstly captured and converted into the carbonate in LiF-Li 2 O melts, and subsequently electrolyzed. The morphologies of the carbon material obtained on the cathode were dependent on the electrolysis potentials. The rate of CO 2 and O 2 production in the anode gas was related to the reaction process, current density, and potentials. Electrochemical decomposition of CO 2 into carbon materials and oxygen gas in a fluoride melt was proved to be feasible.
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CELLULOSE
·
2020
·Vol. 28
·期 2
·1139-1152
·
IF 4.21
Gao Simeng,Su Jing,Wang Wencong,Fu Jiajia,Wang Hongbo
In this work, a novel formulation of polysulfobetaine, poly (sulfobetaine-acrylamide-allyl glycidyl ether) (PSPB-AM-AGE), was synthesized and grafted onto cotton. The synthesis of PSPB-AM-AGE and its grafting on the cotton fabrics were confirmed by FTIR, XPS and SEM. The PSPB-AM-AGE treated cotton fabrics exhibited a high level of antibacterial rate against both Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) , which are 95.18% and 98.74%, separately, as well as a good laundry durability. The mechanical tests showed that the essential cotton properties can be largely preserved in the treatment process. Moreover, the hydrophilicity, air and water permeability of the cotton were improved after treated with PSPB-AM-AGE, indicating a better wearing comfort performance. The whiteness of the cotton fabrics did not decrease significantly.
The safety evaluation demonstrated that PSPB-AM-AGE had no cytotoxicity. The developed antibacterial finishing introduced a new method to apply polysulfobetaine interfaced on cellulose, providing great potential for biomedical fabric application.
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2020
·Vol. 326
·期 3
·1843-1852
·
IF 1.137
Wang Zili,Liu Zhirong,Ye Tianzhen,Wang Yun,Zhou Limin
The tannic acid-chitosan hydrothermal carbon (TCHC) by hydrothermal carbonization is first used in uranium(VI) adsorption. The characterization of HCTC was investigated by scanning electron microscopy, X-ray diffraction, infrared spectroscopy (FTIR). The effects of pH, adsorbent dosage, initial U(VI) concentration, temperature and contact time on the adsorption of uranium(VI) were expressed in batch experiments. A maximum adsorption capacity 96.99 mg/g has been achieved at pH = 5.5, T = 25 °C and initial concentration of U(VI) solution 80 mg/L. The adsorption data fit well with the Langmuir model and pseudo second order kinetics model, indicating that uranium(VI) was monolayer covered on the surface of the material, and the adsorption process was mainly chemisorption. Thermodynamic data indicates that the immobilization of uranium(VI) to the material surface was spontaneous and endothermic. TCHC in low-cost is a promising adsorbent for uranium(VI) adsorption.
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