Materials Today Communications
·
2023
·
IF 3.8
Sheng Gong,Xuhong Liu,Haiyan Liao,Xiaoqiang Lin,Qizhang Huang,Murtaza Hasan,Xugang Shu,Xinhua Zhou,Sundaram Gunasekaran
Copper has been widely used in bacteriostatic materials and pesticides, which make it as a potential threat for human health. The development of an electrochemical sensor with high selectivity and sensitivity to copper ions as well as the practicability is an urgent need. In this work, novel chitosan grafted L -cysteine (Cys-CTS) was prepared and characterized by NMR, FT-IR spectra, Raman spectra, XRD . Functionality of Cys-CTS was explored by the CV, and EIS . Presence of sulfur and copper in conjugation and Cys-CTS/Cu(II) composite was confirmed by SEM and EDX analysis. In electrochemical characterizations, the Cys-CTS exhibited higher electron transfer ability than CTS. Then, the Cys-CTS, as the functional monomer, was used to fabricate an ion-imprinted electrode while the electrode had been modified with nitrogen-doped reduced graphene oxide (N-RGO) before. The introduction of N-RGO allowed the detection current of copper ions to be increased significantly. Under the optimal parameters, the modified electrode has a wide linear detection range (0.25–140 μmol L −1 ) and a low detection limit (0.1 μmol L −1 ). Tailoring of L -cysteine conjugated chitosan carbon electrode has better detection performance than CTS alone in the same conditions. In the detection tests of tap water and drinking water, the excellent accuracy and recovery rate (varied from 92.1% to 103.4%) was obtained. The current work can be used for detection of heavy metal in soil as well in water.
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CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2022
·
IF 3.898
Yafei Su,Xuke Zhang,Hui Li,Donglai Peng,Yatao Zhang
Layered assembled membranes of 2D leaf-like zeolitic imidazolate frameworks (ZIF-L) nanosheets have received great attention in the field of water treatment due to the porous structure and excellent antibacterial ability, but the dense accumulation on the membrane surface and the low permeate flux greatly hinder their application. Herein, we synthesized mHNTs (modified halloysite nanotubes)/ZIF-L nanocomposites on modified mHNTs by in situ growth method. Interestingly, due to the different size of mHNTs and ZIF-L, mHNTs were packed in ZIF-L nanosheets. The hollow mHNTs provided additional transport channels for water molecules, and the accumulation of the ZIF-L nanosheets was decreased after assembling mHNTs/ZIF-L nanocomposites into membrane by filtration. The prepared mHNTs/ZIF-L membrane presented high permeate flux (59.6 L·m −2 ·h −1 ), which is 2–4 times of the ZIF-L membranes (14.8 L·m −2 ·h −1 ). Moreover, mHNTs/ZIF-L membranes are intrinsically antimicrobial, which exhibit extremely high bacterial resistance. We provide a controllable strategy to improve 2D ZIF-L assembles, and develops novel membranes using 2D package structure as building units.
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Asia-Pacific Journal of Chemical Engineering
·
2022
·Vol. 18
·期 2
·e2871
·
IF 1.777
Biao Jin,Shanshan Liu,Dongri Jin
The design of electrode materials for sensitive electrochemical sensors is important for the rapid detection of ascorbic acid. Using Physalis alkekengi L. husks (PaLH) as the carbon precursor, PaLH-derived carbon materials (PCM) were prepared by high temperature carbonization, and hierarchical porous carbon materials (KPCM) were prepared by KOH activation. The carbon materials were characterized by scanning electron microscopy, X-ray diffraction, and isothermal nitrogen adsorption and desorption. KPCM had a larger specific surface area (1345.45 m 2 g −1 ) and more micro/mesopores than PCM without KOH activation. Two types of carbon materials, PCM and KPCM, were used as electrode modifiers, and the electrochemical properties of KPCM/GCE and PCM/GCE (GCE = glassy carbon electrode) were investigated. KPCM/GCE had a higher electron-transfer rate, higher electrochemically active area, smaller charge-transfer resistance, wider potential window, and higher catalytic activity for ascorbic acid detection. An ascorbic acid electrochemical sensing platform constructed with KPCM/GCE showed high sensitivity (334.03 μA mM −1 cm −2 and 134.52 μA mM −1 cm −2 ) and a low detection limit (0.92 μM) ( S/N = 3) in the linear range of 0.005–1.6 mM. This method was applied to the analysis and determination of ascorbic acid in chewable vitamin C tablets.
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MOLECULES
·
2022
·Vol. 28
·期 1
·46
·
IF 4.927
Huaizhi Pan,Biao Zheng,Hui Yang,Yingying Guan,Liuyang Zhang,Xiaoli Xu,Aimin Wu,Huiling Li
Hemicellulose is the second most abundant natural polysaccharide and a promising feedstock for biomaterial synthesis. In the present study, the hemicellulose of loblolly pine was obtained by the alkali extraction-graded ethanol precipitation technique, and the hemicellulose-polyvinyl alcohol (hemicellulose-PVA) composite film was prepared by film casting from water. Results showed that hemicellulose with a low degree of substitution is prone to self-aggregation during film formation, while hemicellulose with high branching has better compatibility with PVA and is easier to form a homogeneous composite film. In addition, the higher molecular weight of hemicellulose facilitates the preparation of hemicellulose-PVA composite film with better mechanical properties. More residual lignin in hemicellulose results in the better UV shielding ability of the composite film. This study provides essential support for the efficient and rational utilization of hemicellulose.Keywords:loblolly pine;hemicellulose;graded ethanol precipitation;hemicellulose-polyvinyl alcohol composite film
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Drug Design Development and Therapy
·
2023
·
IF 4.8
Weiya Zeng,Yuan Fang,Suifen Mo,Caihong Shen,Huiling Yang,Guihua Luo,Luhua Xiao,Ruoting Zhan,Ping Yan
Purpose Rubia cordifolia L. (RC) is a classic herbal medicine for the treatment of rheumatoid arthritis (RA) and has been used since ancient times. The ethanol extract of Rubia cordifolia L. (RCE) showed obvious anti-RA effects in our previous study. However, further potential mechanisms require more exploration. We aimed to investigate the mechanism of RCE for the treatment of RA by integrating metabolomics and network pharmacology in this study.Methods An adjuvant-induced arthritis (AIA) rat model was established, and we evaluated the therapeutic effects of RCE. Metabolomics of serum and urine was used to identify the differential metabolites. Network pharmacology was applied to determine the key metabolites and potential targets. Finally, the potential targets and compounds of RCE were verified by molecular docking.Results The results indicated that RCE suppressed foot swelling and alleviated joint damage and also had anti-inflammatory properties by inhibiting the expressions of tumor necrosis factor (TNF)-α, Interleukin (IL)-1β, prostaglandin E2 (PGE2), and P65. Ten and seven differential metabolites were found in the serum and urine, respectively, of rats. Six key targets, ie, phospholipase A2 group IIA (PLA2G2A), phospholipase A2 group X (PLA2G10), cytidine deaminase (CDA), uridine-cytidine kinase 2 (UCK2), charcot-leyden crystal galectin (CLC), and 5′,3′-nucleotidase, mitochondrial (NT5M), were discovered by network pharmacology and metabolite analysis and were found to be related to glycerophospholipid metabolism and pyrimidine metabolism. Molecular docking confirmed that the favorable compounds showed affinities with the key targets, including alizarin, 6-hydroxyrubiadin, ruberythric acid, and munjistin.Conclusion This study revealed the underlying mechanisms of RCE and provided evidence that will allow researchers to further investigate the functions and components of RCE against RA.
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JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2023
·Vol. 27
·期 3
·753-761
·
IF 2.5
Chu Youqun,Zhang Huixuan,Zhou Huihui,Xu Tengfei,Yan Hui,Huang Zhangkao,Zhao Fengming
The nano-Ag–TiO 2 hollow microsphere precursors were prepared by the one-pot solvothermal method using L-tyrosine as the template agent and reducing agent. Subsequently, the nano-Ag–TiN hollow microsphere composites were formed by reducing nitride in an ammonia-filled atmosphere. The esterification of ethanol solvent and L-tyrosine microdroplet template generates traces of water in situ for the hydrolysis of alkane titanium. As the L-tyrosine microdroplet templates are sacrificed and incorporated into the titanium dioxide matrix, a hybridized hollow structure is formed. With the help of L-tyrosine, the surface of Ag–TiO 2 hollow microsphere precursors appeared folded rough surface, and the nanosilver was mostly distributed in the TiO 2 spherical shell. The constructed Ag–TiO 2 hollow microsphere demonstrated a good linear relationship between the current response value and the concentration in the range of 0.2–220 μM of H 2 O 2 , with the lowest detection limit of 0.04 μM. In the same concentration range, whereas the lowest detection limit of Ag–TiN hollow microsphere was 0.02 μM. The detection results of H 2 O 2 revealed that the Ag–TiN/HMS electrode has outstanding interference resistance, stability, and repeatability.
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POLYMERS FOR ADVANCED TECHNOLOGIES
·
2023
·Vol. 34
·期 5
·1608-1621
·
IF 3.4
Xujian Li,Xumin Chen,Zhixiao Ji,Luqi Pan,Yi Liu,Xiao Yang,Changcan Shi
Rapid hemostasis, biosafety, and adaptability to different bleeding sites are the focus of research on hemostatic materials. In this work, an efficient and simple preparation of aldehyde starch hemostatic microspheres (ASHMs) crosslinked with L-cystine dimethyl ester was developed. Through a series of physicochemical parameters and in vitro and in vivo hemostatic properties measurements, the results showed that under the optimal crosslinking degree, ASHMs had a regular and uniform spherical shape, and it had a liquid suction capacity of up to 880%. At the same time, the aldehyde groups on its surface can increase the adhesion and aggregation of blood cells, thereby enhancing the hemostatic effect, which can be considered as a synergistic effect. More importantly, ASHMs have good biocompatibility and minimal intradermal irritation. Taken together，ASHMs could be used as potential novel hemostatic materials for surgical treatment.
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JOURNAL OF HAZARDOUS MATERIALS
·
2023
·
IF 13.6
Mingwei Deng,Shengwang Wang,Huagang Huang,Daihua Ye,Xizhou Zhang,Yongdong Wang,Zicheng Zheng,Tao Liu,Tingxuan Li,Haiying Yu
Hydrogen peroxide (H 2 O 2 ) is a vital signaling molecule in response to cadmium (Cd) stress in plants. However, the role of H 2 O 2 on Cd accumulation in root of different Cd-accumulating rice lines remains unclear. Exogenous H 2 O 2 and 4-hydroxy-TEMPO (H 2 O 2 scavenger) were applied to investigate the physiological and molecular mechanisms of H 2 O 2 on Cd accumulation in the root of a high Cd-accumulating rice line Lu527–8 through hydroponic experiments. Interestingly, it was found Cd concentration in the root of Lu527–8 increased significantly when exposed to exogenous H 2 O 2 , while reduced significantly when exposed to 4-hydroxy-TEMPO under Cd stress, proving the role of H 2 O 2 in regulating Cd accumulation in Lu527–8. Lu527–8 showed more Cd and H 2 O 2 accumulation in the roots, along with more Cd accumulation in cell wall and soluble fraction, than the normal rice line Lu527–4. In particular, more pectin accumulation, especially low demethylated pectin, was observed in the root of Lu527–8 when exposed to exogenous H 2 O 2 under Cd stress, resulting in more negative functional groups with greater capacity to binding Cd in the root cell wall of Lu527–8. It indicated that H 2 O 2 -induced cell wall modification and vacuolar compartmentalization contributes greatly to more Cd accumulation in the root of the high Cd-accumulating rice line.
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Advanced Science
·
2023
·
IF 15.1
Juan He,Fuquan Ma,Wenpu Xu,Xuexia He,Qi Li,Jie Sun,Ruibin Jiang,Zhibin Lei,Zong-Huai Liu
Ti 3 C 2 T x Quantum dots (QDs)/L-Ti 3 C 2 T x fiber electrode (Q 3 M 7 ) with high capacitance and excellent flexibility is prepared by a wet spinning method. The assembled units Ti 3 C 2 T x nanosheets (NSs) with large size (denoted as L-Ti 3 C 2 T x ) is obtained by natural sedimentation screen raw Ti 3 AlC 2 , etching, and mechanical delamination. The pillar agent Ti 3 C 2 T x QDs is fabricated by an ultrasound method. Q 3 M 7 fiber electrode gave a specific capacitance of 1560 F cm −3 , with a capacity retention rate of 79% at 20 A cm −3 , and excellent mechanical strength of 130 Mpa. A wide temperature all-solid-state the delaminated montmorillonite (F-MMT)/Polyvinyl alcohol (PVA) dimethyl sulfoxide (DMSO) flexible hydrogel (DHGE) (F-MMT/PVA DHGE) Q 3 M 7 fiber supercapacitor is assembled by using Q 3 M 7 fiber as electrodes and F-MMT/PVA DHGE as electrolyte and separator. It showed a volume specific capacitance of 413 F cm −3 at 0.5 A cm −3 , a capacity retention of 97% after 10 000 cycles, an energy density of 36.7 mWh cm −3 at a power density of 311 mW cm −3 , and impressive capacitance and flexibility over a wide temperature range of −40 to 60 °C. This work provides an effective strategy for designing and assembling wide temperature all-solid-state fiber supercapacitors with optimal balance of capacitive performance and flexibility.
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BIOMACROMOLECULES
·
2023
·
IF 6.2
Junhai Huang,Yuan Ma,Kaiteng Pang,Xiaochen Ma,Zhiyu Zheng,Daorong Xu,Ke Xiong,Bin Yu,Liqiong Liao
To achieve osteogenesis, angiogenesis, and neurogenesis for repairing bone defects, we constructed an anisotropic microspheres–cryogel composite loaded with magnesium l-threonate (MgT). These composites were prepared by the photo-click reaction of norbornene-modified gelatin (GB) in the presence of MgT-loaded microspheres through the bidirectional freezing method. The composites possessed an anisotropic macroporous (around 100 μm) structure and sustained release of bioactive Mg2+, which facilitate vascular ingrowth. These composites could significantly promote osteogenic differentiation of bone marrow mesenchymal stem cells, tubular formation of human umbilical vein vessel endothelial cells, and neuronal differentiation in vitro. Additionally, these composites significantly promoted early vascularization and neurogenesis as well as bone regeneration in the rat femoral condyle defects. In conclusion, owing to the anisotropic macroporous microstructure and bioactive MgT, these composites could simultaneously promote bone, blood vessel, and nerve regeneration, showing great potential for bone tissue engineering.
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Biotechnology for Biofuels and Bioproducts
·
2023
·Vol. 16
·期 1
·1-13
·
IF 0
Gao Hui,Li Mengxuan,Wang Qing,Liu Tingting,Zhang Xian,Yang Taowei,Xu Meijuan,Rao Zhiming
ATP, an important cofactor, is involved in many biocatalytic reactions that require energy. Polyphosphate kinases (PPK) can provide energy for ATP-consuming reactions due to their cheap and readily available substrate polyphosphate. We determined the catalytic properties of PPK from different sources and found that PPK from Cytophaga hutchinsonii ( Ch PPK) had the best catalytic activity for the substrates ADP and polyP 6 . An extracellular–intracellular dual system was constructed to high-throughput screen for better catalytic activity of Ch PPK mutants. Finally, the specific activity of Ch PPK D82N-K103E mutant was increased by 4.3 times. Therefore, we focused on the production of L-theanine catalyzed by GMAS as a model of ATP regeneration. Supplying 150 mM ATP, GMAS enzyme could produce 16.8 ± 1.3 g/L L-theanine from 100 mM glutamate. When 5 mM ATP and 5 U/mL Ch PPK D82N-K103E were added, the yield of L-theanine was 16.6 ± 0.79 g/L with the conversion rate of 95.6 ± 4.5% at 4 h. Subsequently, this system was scaled up to 200 mM and 400 mM glutamate, resulting in the yields of L-theanine for 32.3 ± 1.6 g/L and 62.7 ± 1.1 g/L, with the conversion rate of 92.8 ± 4.6% and 90.1 ± 1.6%, respectively. In addition, we also constructed an efficient ATP regeneration system from glutamate to glutamine, and 13.8 ± 0.2 g/L glutamine was obtained with the conversion rate of 94.4 ± 1.4% in 4 h after adding 6 U/ mL GS enzyme and 5 U/ mL Ch PPK D82N-K103E , which further laid the foundation from glutamine to L-theanine catalyzed by GGT enzyme. This proved that giving the reaction an efficient ATP supply driven by the mutant enzyme enhanced the conversion rate of substrate to product and maximized the substrate value. This is a positively combination of high yield, high conversion rate and high economic value of enzyme catalysis. The mutant enzyme will further power the ATP-consuming biocatalytic reaction platform sustainably.
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International Journal of Electrochemical Science
·
2023
·
IF 1.5
Peilong Wang,Xu Liu,Qingqing Hu,Hui Gao,Wei Ma
A simple and rapid electrochemical method based on a poly(L-arginine)-electrochemically reduced graphene oxide-modified glassy carbon electrode fabricated by cyclic voltammetry has been developed for the determination of tartrazine. Compared with the bare glassy carbon electrode, the modified electrode achieved a well-defined and enhanced oxidation peak due to the increased conductivity and electrochemical active surface area. The bare glassy carbon electrode and the modified electrode were characterized by scanning electron microscopy and electrochemical impedance spectroscopy. The electrocatalytic oxidation behaviors of tartrazine on the modified electrode were investigated using cyclic voltammetry and differential pulse voltammetry. The voltammetric peak current of tartrazine exhibits good linearity in the range of 1.00×10 -6 -2.50×10 -4 mol L -1 under the optimal differential pulse voltammetry conditions, with a detection limit of 2.5×10 -7 mol L -1 (at an S/N of 3). This proposed method has also been applied for quantitative analysis of tartrazine in some carbonated beverage and fruit juice samples, with satisfactory results.
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