CARBOHYDRATE POLYMERS
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2022
·
IF 10.723
Yizhe Zhang,Tingting Cai,Zhiwei Zhao,Bing Han
Adsorbents with highly efficient and selective recovery performance towards uranium are significantly demanded for the sustainable nuclear power production. Herein, poly(amidoxime)-graft-magnetic chitosan (P(AO)-g-MC) was synthesized through functionalizing magnetic chitosan with polyacrylonitrile followed by amidoximation process. Under magnetic field, P(AO)-g-MC can be separated from the solution in 10 s. Owing to the strong affinity of high-density amidoxime groups towards uranium, P(AO)-g-MC showed remarkable adsorption capacity, rapid kinetics and good regeneration performance in uranium spiked aqueous solution. Notably, the 7-day uranium adsorption capacity of P(AO)-g-MC from natural seawater in column mode was up to 5.14 mg/g, 12 times that of vanadium. The excellent uranium uptake performance over vanadium originated from the strong coordination by N and O in amidoxime groups according to theoretical simulation. The advantages of easy separating and high selectivity make P(AO)-g-MC a very potential uranium adsorbent in natural seawater.
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Biomaterials Science
·
2022
·Vol. 11
·期 1
·278-287
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IF 7.59
Xiulin Cheng,Panjing Yin,Ting Li,Lincong Luo,Yang Yang,Ling Wang,Weiwei Su,Yilin Wang,Yanbing Li,Yanfang Wang,Yaobin Wu,Wenhua Huang
Retinal pigment epithelial (RPE) cell transplantation is being explored as a feasible approach for treating age-related macular degeneration. The low aggregation ability of RPE cell suspensions or microtissues after transplantation has limited cell utilisation. Therefore, alternative transplantation strategies should be explored to induce cell aggregation and maintain cell viability. Herein, we propose a composite hydrogel that encapsulates gelatin methacryloyl (GelMA)/chitosan microspheres (GCMSs) as ARPE-19 cell transplantation carriers. The diameter of the GCMS was adjusted by tuning the parameters of the microfluidic devices, yielding a cell-adhering platform that induced uniform cell spreading. The live/dead assay and immunofluorescence results showed that ARPE-19 cells adhered and spread uniformly around the microspheres. Moreover, the hydrogel sheets were used to provide an aggregated protective shell, and the ARPE-19 cells on the microspheres encapsulated within these hydrogel sheets remained viable post-injection and produced fewer reactive oxygen species after cyclic stretching. Furthermore, we found that the composite hydrogel was biodegradable and biocompatible in vivo. Therefore, GCMSs provide an injectable microcarrier for ARPE-19 cells, and the hydrogel provides an aggregated protective shell in this novel platform, which has considerable potential for an alternative injectable and highly aggregated RPE cell transplantation strategy design.
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Polymers
·
2023
·Vol. 15
·期 24
·4632
·
IF 5
Huimei Wu,Yishan Lou,Zhonghui Li,Xiaopeng Zhai,Fei Gao
To meet the escalating demand for oil and gas exploration in microporous reservoirs, it has become increasingly crucial to develop high-performance plugging materials. Through free radical grafting polymerization technology, a carboxymethyl chitosan grafted poly (oligoethylene glycol) methyl ether methyl methacrylate acrylic acid copolymer (CCMMA) was successfully synthesized. The resulting CCMMA exhibited thermoresponsive self-assembling behavior. When the temperature was above its lower critical solution temperature (LCST), the nanomicelles began to aggregate, forming mesoporous aggregated structures. Additionally, the electrostatic repulsion of AA chains increased the value of LCST. By precisely adjusting the content of AA, the LCST of CCMMA could be raised from 84.7 to 122.9 °C. The rheology and filtration experiments revealed that when the temperature surpassed the switching point, CCMMA exhibited a noteworthy plugging effect on low-permeability cores. Furthermore, it could be partially released as the temperature decreased, exhibiting temperature-switchable and self-adaptive plugging properties. Meanwhile, CCMMA aggregates retained their reversibility, along with thermal thickening behavior in the pores. However, more detailed experiments and analysis are needed to validate these claims, such as a comprehensive study of the CCMMA copolymer’s physical properties, its interaction with the reservoir environment, and its performance under various conditions. Additionally, further studies are required to optimize its synthesis process and improve its efficiency as a plugging material for oil and gas recovery in microporous reservoirs.Keywords:temperature-switchable;intelligent fluid;adaptive;rheological properties;filtration loss
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CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Ke Liu,Juan Yang,Jiale Liu,Qin Shuai,Yusuke Yamauchi,Minsu Han,Lijin Huang
Covalent organic framework (COF) aerogels have attracted significant interest due to their broad range of potential applications. However, synthesizing COF aerogels with tailored structures and robust mechanical stability remains a formidable challenge. In this work, we present a double-cross-linking strategy to prepare a series of compressible COF/chitosan (COF/CS) aerogels under mild conditions. By harnessing chemical cross-linking and physical interactions, such as electrostatic and hydrogen bonding, ionic COF powders containing sulfonic acid groups ( i.e. , TpPa-SO 3 H) are immobilized and connected with CS, forming a three-dimensional interconnected network. Impressively, the ratio of COF to CS and the size of the COF/CS aerogels can be easily controlled by adjusting the processing parameters. The resulting COF/CS aerogels possess a highly porous structure and low density, enabling the aerogels to self-float and facilitating practical applications and recycling. Due to these remarkable characteristics, TpPa-SO 3 H/CS aerogel demonstrates excellent adsorption capacity, effectively removing sulfamerazine from aqueous solutions with an adsorption capacity of 102.5 mg·g −1 . Moreover, the aerogel can be reused in three adsorption–desorption cycles without significant capacity loss. This proposed method offers a facile, eco-friendly, and scalable approach for producing highly compressive COF-based aerogels, thereby accelerating the practical utilization of COFs and contributing to environmental remediation.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2023
·
IF 4.2
Si-Ke Chen,Da-Wei Pan,Zhuang Liu,Wei Wang,Rui Xie,Xiao-Ting Mu,Xiao-Jie Ju,Liang-Yin Chu
A simple microfluidic strategy is proposed for the controllable preparation of calcium alginate/chitosan (CaA/CS) microcapsules with ultrathin shells for peroxidase immobilization. In this study, the composite microcapsules are composed of CaA and CS, which are beneficial to improve the stability of CaA microcapsules, and are generated using a two-stage capillary microfluidic device. The inner layer of the composite capsule shells is ionically cross-linked CaA, and the outer layer is covalently cross-linked CS. Moreover, the Fe3O4 magnetic nanoparticles are added to facilitate the recovery and reuse of the composite microcapsules. The morphology, permeability, encapsulation efficiency, enzyme activity, and reusability of CaA/CS microcapsules are investigated. The overall thickness of the double-layered shell is about 346 nm. Meanwhile, the microcapsules have good molecular selective permeability, excellent encapsulation performance, stable enzyme activity, and good stability for reusability. The composite microcapsules retained above 80% of residual activity after six recycle uses. The developed novel strategy for fabricating peroxidase-immobilized CaA/CS microcapsules with ultrathin shells is of great potential value for enzyme immobilization applications.
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FOOD CHEMISTRY
·
2023
·
IF 8.8
Xiaoxia Chen,Yixi Li,Yu-Long Qiu,Gong-Liang Zhang,Hongshun Hao,Hong-Man Hou,Jingran Bi
To develop food packaging with good antibacterial activity and mechanical performance, four amino carboxymethyl chitosan (ACC)//dialdehyde starch (DAS) /polyvinyl alcohol (PVA) films were prepared by Schiff base and hydrogen bond interactions for efficient loading and release of ε-polylysine (ε-PL). The effects of the Schiff base reaction on the physicochemical properties of the films were explored based on the different aldehyde group contents in DAS. The ACC//DAS 4 /PVA film exhibited a tensile strength of 62.5 MPa, and the water vapor and oxygen permeability was 8.77 × 10 -3 ·g·mm/m 2 ·d·kPa and 0.15 × 10 3 ·cm 3 ·mm/m 2 ·d, respectively. By leveraging the Schiff base reaction, the film swelling properties were improved by adjusting the cross-link density, mesh size, and molecular mass between the cross-links. The ACC//DAS 4 /PVA film could efficiently load ε-PL with a value of 98.44% and long-term release in a food simulant of 10% ethanol at 25 °C for 120 min. Moreover, the ACC-ε-PL//DAS 4 /PVA film was successfully used for salmon preservation.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Xiaoxiao Lin,Zesheng Liu,Ruipeng Chen,Yue Hou,Ran Lu,Shuang Li,Shuyue Ren,Zhixian Gao
Removing noxious dyes and detecting excessive metal ions in water are both effective means to prevent damage from contaminants and ensure water safety. The emphasis problems were addressed by preparation a polyacrylamide chitosan (PAAM/CS) hydrogel. Polyacrylamide (PAAM) provides overall mechanical strength to carry loads and facilitate circulation, chitosan (CS) provides adsorption positions with high adsorption capacity. Which made that PAMM/CS hydrogel efficiently performed sorption of xylenol orange (XO). As the functional dye, XO binds to PAAM/CS and confers colorimetric properties on PAAM/CS hydrogels. XO sorbed hydrogel realized fluorescence dual-signal detection of Fe 3+ and Al 3+ in water. The significant swelling and adsorption potency of the hydrogel, combined with the dual-signal detection capability of XO sorbed hydrogel, make this hydrogel a versatile material for environmental applications.
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BIOMACROMOLECULES
·
2023
·
IF 6.2
Xiaokang Na,Bowen Zou,Xiaohan Zheng,Ming Du,Beiwei Zhu,Chao Wu
Innovation in green, convenient, and sustainable antimicrobial packaging materials for food is an inevitable trend to address global food waste challenges caused by microbial contamination. In this study, we developed a biogenic, hydrophobic, and antimicrobial protein network coating for food packaging. Experimental results show that disulfide bond breakage can induce the self-assembly of bovine albumin (BSA) into protein networks driven by hydrophobic interactions, and chitosan oligosaccharide (COS) with antimicrobial activity can be stably bound in this network by electrostatic interactions. The inherent antimicrobial activity of COS and the numerous hydrophobic regions on the surface of the BSA-network give the BSA@COS-network significant in vitro antimicrobial ability. More importantly, the BSA@COS-network coating can prolong the onset of spoilage of strawberries in various packaging materials by nearly 3-fold in storage. This study shows how surface functionalization via protein self-assembly is integrated with the biological functioning of natural antibacterial activity for advanced food packaging applications.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2022
·Vol. 23
·期 18
·10542
·
IF 6.208
Yuheng Qiu,Kaiqi Ding,Liwen Tang,Ziyu Qin,Mengting Li,Xueqiong Yin
The demand for rare earth metal increases rapidly in the modern high-tech industry and therefore the accumulation of rare earth metal ions from an aqueous environment becomes a significant concern worldwide. In this paper, a water-recyclable chitosan-based La3+-imprinted thermoresponsive hydrogel (CLIT) was prepared to accumulate La3+from solution. The CLIT was characterized by DSC, FITR, Raman spectroscopy, XPS, and SEM, which revealed obvious reversible thermosensitivity and imprinted sites of La3+ions. An adsorption capacity of 112.21 mg/g to La3+ions was achieved on CLIT under its optimum adsorption conditions (pH 5, 50 °C, 60 min). The adsorption could be well illustrated by second-order kinetics and Freundlich isotherm models. The La3+-adsorbed CLIT could be recycled only by rinsing with 10 °C cold water, with a desorption rate of 96.72%. After ten cycles of adsorption-desorption, CLIT retained good adsorption capability. In the solution containing six ions, the adsorption coefficients kLa3+/Mn+of CLIT were 2.04–3.51 times that of non-imprinted hydrogel, with kLa3+/Y3+, kLa3+/Gd3+, kLa3+/Al3+, kLa3+/Fe3+and kLa3+/Cu2+being 1.67, 2.04, 3.15, 2.72 and 4.84, respectively.Keywords:thermoresponsive hydrogel;La3+-imprinting;rare earth metal
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COLLOID AND POLYMER SCIENCE
·
2022
·Vol. 300
·期 10
·1187-1195
·
IF 2.434
Li Xin,Gao Yongfeng,Li Yaozong,Li Yanqun,Liu Haotian,Yang Zhuohong,Wu Hong,Hu Yang
Cinnamon essential oil (CNO) is a natural and renewable antibacterial agent. However, CNO is highly volatile and unstable, which limits its practical application as a long-term and wide antibacterial agent. In order to improve the CNO stability, we have microencapsulated CNO into composite microcapsules basing on Pickering emulsion stabilized by silica (SiO 2 ) nanoparticles. The CNO-loaded composite microcapsules possess the hybrid microcapsule shell including SiO 2 , xanthan gum and chitosan. Moreover, the results show that the microcapsules have spherical appearance. Microencapsulation technique effectively promotes the CNO stability, and the loaded CNO is slowly released from microcapsules. The antibacterial test indicates that the minimal inhibitory concentration of microcapsules was 2 mg mL −1 against Escherichia coli and Staphylococcus aureus , and the microcapsules can play an effective long-term antibacterial effect. Thus, Pickering emulsion templates is a convenient and effective technique to construct antibacterial essential oil-contained microcapsules, which can be used as long-term antibacterial agents.
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CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Yajie Zhong,Farzad Seidi,Yilin Wang,Ling Zheng,Yongcan Jin,Huining Xiao
Herein, an injectable self-healing hydrogel with inherent antibacterial activity was fabricated based on the dynamic covalent bond formation between boronic acid and catechol groups in quaternized chitosan as building blocks in conjunct with the in-situ encapsulation of epigallocatechin-3-gallate (EGCG, a green tea derivative). Benefiting from the catechol groups and therapeutic effect of EGCG, the resulting natural-based injectable hydrogels showed excellent antibacterial and antioxidant dual functions in preventing bacterial infection and scavenging radicals. The hydrogels loaded with EGCG also exhibited good biocompatibility along with contact-active antibacterial activity via a “capture and kill” strategy. The dynamic covalent bonding enables shear-thinning delivery of the gels via syringe, followed by rapid self-healing. Additionally, the in vivo wound healing evaluation in a full-thickness skin defect model revealed the appreciable and regenerative wound healing performance of the hydrogels, demonstrating their great potential as novel wound dressings for wound management.
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CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Chengkun Liu,Chang Liu,Zhuang Shi,Wei Lu,Zhiyuan Liu,Shihai Liu,Xiaojuan Wang,Xiaoqiang Wang,Fang Huang
This work describes a hemostatic membrane system (or surface coating) based on spray-assisted layer-by-layer electrostatic assemblies of oppositely charged polyphosphate (polyP) and chitosan (Cs). The as-prepared membrane formed a robust micro-stratified porous structure with high flexibility. Both blood clotting test and rodent hepatic severe hemorrhage model revealed the excellent hemostatic performance of the membrane system, benefitting from the robust assembly and synergistic effect of polyP/Cs as well as membrane surface chemistry. Compared to Cs-topped membrane surface, polyP-sprayed one exhibited further improved hemostatic effect via promoting fibrin formation . Besides, comprehensive in vitro and in vivo evaluations demonstrated good biocompatibility and biodegradability of the membrane. The present approach that integrated the hemostasis-stimulating capability of polyP/Cs with facile spraying method is highly scalable and flexible, which is envisioned to be adapted readily for other hemostatic polyelectrolytes and surface functionalization of diverse existing hemostatic products on demand.
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