Journal of Analysis and Testing
·
2019
·Vol. 3
·期 3
·269-276
·
IF 0
Liu Liu,Jiang Hui,Wang Xuemei
Nanozymes are a class of mimic enzymes that have both unique properties of nanomaterials and catalytic functions. They are widely used in medicine, food, agriculture, and environment due to their high catalytic efficiency, stability, economy, and large-scale preparation. In this work, a simple, gentle method was applied to synthesize adenosine phosphates (AXP) templated gold nanoparticles (Au NPs) with small size, good optical properties, and peroxidase-like activities. In the presence of hydrogen peroxide (H 2 O 2 ), the peroxidase substrate 3, 3′, 5, 5′-tetramethylbenzidine (TMB) could be oxidized to form blue-colored oxidized TMB (oxTMB), which demonstrates that the AuAXP NPs have peroxidase-like activities. Interestingly, the introduction of bivalent metal ions into AuAXP NPs allows their reusability. Among them, after three rounds of recycling, the catalytic activity of Mg@AuAMP could still reach 92.69% compared to the original level, which showed excellent reusability. In addition, the glutathione (GSH) detection was realized with a linear detection range of 0–200 μM due to the GSH-induced loss of peroxidase-like activities. Overall, this work provides a new idea of recycling for biosensor and catalytic analysis.
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CELLULOSE
·
2019
·Vol. 26
·期 16
·8829-8841
·
IF 3.917
Huang Hongye,Liu Meiying,Chen Junyu,Mao Liucheng,Wan Qing,Wen Yuanqing,Deng Fengjie,Zhou Naigen,Zhang Xiaoyong,Wei Yen
Abstract Since the first discovery by Tang in 2001, aggregation-induced emission (AIE) phenomenon has attracted considerable research interest in various fields. In this contribution, AIE-active composites (named as An-HPG-β-CD) have been fabricated via conjugation of AIE-active compound An-B(OH) 2 and hyperbranched polyglycerol functionalized β cyclodextrin (HPG-β-CD) based on dynamic phenyl borate for the first time. The potential biomedical applications of these AIE-active composites for biological imaging and drug delivery applications were further explored. The successful preparation of An-HPG-β-CD composites was confirmed through a series of characterization techniques. The An-HPG-β-CD composites possess great water dispersibility, low cytotoxicity, excellent fluorescence properties and uniform size and morphology, which make them promising for cell imaging. Furthermore, the cavities of An-HPG-β-CD composites could be utilized for loading with doxorubicin for drug delivery applications. In conclusion, we have developed a novel method for fabrication of AIE-active An-HPG-β-CD composites through formation of dynamic phenylboronic borate between β cyclodextrin containing hyperbranched polyglycerol and phenylboronic containing AIE dye. These AIE-active composites are of great potential in biological imaging and drug delivery applications. Graphic abstract
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高影响因子
Nano Research
·
2019
·Vol. 12
·期 10
·2543-2548
·
IF 8.515
Wang Rui,Zhang Xuejing,Cai Yichao,Nian Qingshun,Tao Zhanliang,Chen Jun
The rechargeable Li-CO 2 battery has been receiving significant attention owing to its merits of high energy density and the efficient utilization of CO 2 . However, the widely application is plagued by severe security risks, such as leakage, flammability and lithium dendrites growth due to the use of liquid organic electrolytes. Here, a composite solid state electrolyte consisting of polyethylene oxide (PEO) and 20 wt.% Li 7 La 3 Zr 1.4 Ta 0.6 O 12 (LLZTO) was prepared and first introduced into Li-CO 2 battery to solve the problems. The composite solid state electrolyte exhibited high ionic conductivity (1.03 × 10 −1 S·cm −1 at 70 °C), wide electrochemical window (5 V vs. Li + /Li), good mechanical properties and excellent flexibility. Ultimately, the Li symmetric cell with PEO/LLZTO composite solid state electrolyte can operate 1,500 h at a current density of 0.1 mA·cm −2 . The assembled all-solid-state Li-CO 2 battery behaved a long cycle life of 70 cycles at a current density of 100 mA·g −1 with fixed capacity of 1,000 mAh·g −1 . Our work provides new perspective to develop rechargeable all-solid-state Li-CO 2 batteries.
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高影响因子
Nano-Micro Letters
·
2019
·Vol. 11
·期 1
·1-14
·
IF 9.043
Luo Linqu,Song Jianjun,Song Longfei,Zhang Hongchao,Bi Yicheng,Liu Lei,Yin Longwei,Wang Fengyun,Wang Guoxiu
3D hierarchical conductive Sn quantum dots encapsulated in N,S co-doped carbon nanofibers sheathed within rGO scrolls (Sn/NS-CNFs@rGO) were prepared through an electrospinning process.
Flexible Sn/NS-CNFs@rGO electrode exhibits superior long-term cycling stability and high-rate capability in sodium-ion batteries.
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PubMed
高影响因子
CHEMICAL PAPERS
·
2019
·Vol. 74
·期 2
·485-497
·
IF 1.246
Quan Cong,Liu Jiayu,Sun Wei,Cheng Xinjian
It is extremely necessary to detect heavy metals sensitively and selectively, especially the ions that will cause great harm to humans and the environment. This work deals with two fluorescent chemosensors and their outstanding role when detecting Zn 2+ and Cd 2+ ions. First, a small molecular chemosensor (TPB) has been designed and synthesized via Suzuki reaction using one part of benzene-1,3,5-triyltriboronic acid and three parts of 2-bromo-1, 10-phenanthroline as starting materials. And then, its corresponding macromolecular fluorescent chemosensor (PTPB) was synthesized. The infrared spectra, mass spectrometry (MS), and 1 H-NMR were used to study the structures of TPB and PTPB. From what has been studied, the TPB and PTPB were stable in a relative wide pH range. As soon as the Cd 2+ and Zn 2+ ions added, fluorescence of the two sensors TPB and PTPB was changed obviously. In addition, PTPB was found have better performance to both Cd 2+ and Zn 2+ than TPB through the ‘‘molecular wire’’ mechanism. Job’s plots were also be tested, showing that the combination ratio of TPB and PTPB to Cd 2+ and Zn 2+ were both 3:1 (ion/sensor). In addition, the minimum detection limits of the macromolecular chemosensor PTPB for Cd 2+ and Zn 2+ reached 0.424 μM and 1.27 μM, respectively.
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高影响因子
SN Applied Sciences
·
2019
·Vol. 1
·期 8
·1-12
·
IF 0
Zhao Shuyan,Gao Yujie,Tan Jinhui,Zhu Yuntao,Ying Xiaohong,Zhang Mengmeng,Yu Xufeng,You Bo
A facile method to prepare cuprous oxide/bovine serum albumin (Cu 2 O/BSA) hierarchical nanocomposite particles (NCPs) through imitating biomineralization is presented. BSA acted as the structure-directing agents, guiding the nucleation, growth and assembly of Cu(OH) 2 at binding sites to construct the hierarchical structure and then Cu 2 O/BSA NCPs were achieved. The synthesized nanocomposite with hierarchical structure exhibited excellent antibacterial performance. The products obtained were characterized with XRD, TEM, FTIR, EDX and XPS to investigate the formation mechanism of Cu 2 O/BSA hierarchical structure. Cu 2 O/BSA NCPs with size of 20–50 nm built up by several 6–7 nm Cu 2 O nanocrystals with BSA showed better antibacterial performance in the comparative experiments, which was attributed to the special structure and good biocompatibility of the Cu 2 O/BSA NCPs. And the possible mechanism was presented to explain the excellent antibacterial properties of Cu 2 O/BSA NCPs.
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
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2019
·Vol. 321
·期 1
·235-242
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IF 1.186
Zu Jianhua,Fu Lingxiao,Tang Fangdong,He Linfeng
A new pyridyl anion exchange resin (PS-N) was synthesized by chloroacetylation and quaternization on the polystyrene-divinylbenzene microspheres (PS) and was characterized by FT-IR, TGA, and X-ray photoelectron spectroscopy. PS-N was applied to study the removal of Re(VII), a chemical analogue of 99 Tc, to investigate the effect of solution acidity, resin dose and contact time on the adsorption efficiency. The adsorption process corresponded with the Langmuir isotherm model and matches well with pseudo-second-order kinetics. Based on the adsorption results of Re(VII), the adsorption efficiency of 99 Tc was examined to be 99.5% at optimum conditions.
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高影响因子
CATALYSIS LETTERS
·
2019
·Vol. 149
·期 5
·1216-1223
·
IF 2.372
Wu Lian-Kui,Shi Yi-Jie,Su Cheng,Cao Hua-Zhen,Zheng Guo-Qu
Abstract A combined anode, Ti/IrO 2 (0–3.5 h)–Ti/RuO 2 (3.5–7 h) is designed to promote the removal of high concentration of nitrate by a stepwise method. During the electrolysis process, Ti/IrO 2 is used as anode at the first stage to promote the generation of ammonia-N and then Ti/RuO 2 is switched as anode at the next stage to enhance the chlorine evolution. The generated Cl 2 will further react with H 2 O to produce ClO − , which will oxidize ammonia-N to N 2 , therefore improve the nitrate removal efficiency. Results shown that both of the reduction of nitrate and oxidation of the by-product of ammonia-N are enhanced and the total nitrogen removal efficiency is 85% when the initial nitrate concentration is 500 mg L −1 . The avoid using cation exchange membrane not only efficiently reduces the operation cost but also simplifies the operation and maintain procedure. Graphical Abstract
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2019
·Vol. 30
·期 6
·6234-6241
·
IF 2.195
Chen Yufei,Wu Yunzhong,Dai Guoqing,Ma Yingyi
Graphene oxide was obtained by improved Hummers method. Hydrated hydrazine, chitosan or potassium hydroxide was used to prepare different reduced graphene oxide (rGO) in order to choose the best reductant, respectively. The rGO was restored and modified by ionic liquid (NH 2 IL) to obtain functionalized graphene (NH 2 IL – rGO), the matrix (MBAE) was synthesized from 4,4′-diamino diphenyl methane bismaleimide modified by diallyl bisphenol A and Bisphenol A bisallyl ether. NH 2 IL–rGO/MBAE composites were prepared from NH 2 IL–rGO and MBAE via in situ polymerization, and also studied the effect of NH 2 IL–rGO on the properties of composites. The results showed that the micro-morphology of composite existed two-phase structure between the matrix and NH 2 IL–rGO, which gave the material excellent properties. The impact strength and bending strength of the composite reached the maximum and were 15.33 kJ/m 2 and 142 MPa, respectively, when the content of NH 2 IL–rGO was 2 wt%. The thermal decomposition temperature of the composite was 435 °C, the dielectric constant of the composite abruptly reached 84 in the frequency range 10 2 ~ 10 5 Hz.
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高影响因子
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
·
2019
·Vol. 38
·期 1
·1-13
·
IF 5.646
Yang Lehe,Lin Shichong,Kang Yanting,Xiang Youqun,Xu Lingyuan,Li Jifa,Dai Xuanxuan,Liang Guang,Huang Xiaoying,Zhao Chengguang
Background Rhein is a lipophilic anthraquinone extensively found in medicinal herbs. Emerging evidence suggests that rhein has significant antitumor effects, supporting its potential use as an antitumor agent. The IL6/STAT3 signaling pathway has been suggested as an attractive target for the discovery of novel cancer therapeutics.Methods The human pancreatic cancer cell lines AsPC-1, Patu8988T, BxPC-3 and PANC-1, and immunodeficient mice were chosen as models to study the effects of rhein. The potent antiproliferative and proapoptotic effects of rhein were examined by cell viability, cellular morphology, apoptosis and colony formation assays. The STAT3 luciferase report assay, immunostaining analysis and Western blot analysis revealed the inhibition of the IL6/STAT3 signaling axis.Results Apoptosis was induced by adjunctive use of rhein with epidermal growth factor receptor (EGFR) inhibitors in pancreatic cancer cells as verified by cell apoptosis analysis and changes in the expression level of apoptotic/anti-apoptotic proteins BCL-2, BAX, Caspase 3 and Cl-PARP. Suppression of the phosphorylation of STAT3 and EGFR were also observed as a result of the treatment with a combination of rhein and EGFR inhibitors. Most interestingly, it was found that rhein considerably sensitized cells to erlotinib, thus suppressing tumor growth in PANC-1 and BxPC-3 xenograft models. The in vivo anti-tumor effect was associated with increased apoptosis and combined inhibition of the STAT3 and EGFR pathways in tumor remnants.Conclusion sRhein sensitizes human pancreatic cancer cells to EGFR inhibitors through inhibition of STAT3. Taken together, the results indicate that rhein offers a novel blueprint for pancreatic cancer therapy, particularly when combined with EGFR inhibitors.
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PubMed
高影响因子
MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 6
·1-7
·
IF 5.479
Qiao Juan,Liu Qianrong,Wu Han,Cai Huiwu,Qi Li
A fluorescent probe is described for the determination of serum glucose after hepatotoxin-induced liver injury. The probe is based on the use of a water-soluble polymer and has been prepared from a multi-functional azlactone polymer as the linker, amino boronic acid, and Alizarin Red as the signalling moiety. The excitation/emission peaks of the polymeric fluorescent probe are at 468/567 nm. Fluorescence is reduced on addition of glucose. Intensity drops linearly in the 0.1 mM to 14 mM glucose concentration range. The probe was applied to non-enzymatic detection of glucose in rat serum after CCl 4 -induced liver damage.
A polymer based fluorescent probe has been constructed and applied for non-enzymatic monitoring of serum glucose following hepatotoxin induced liver injury.
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高影响因子
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
·
2018
·Vol. 137
·期 2
·437-446
·
IF 2.209
Chen Si,Wang Yating,An Zhihang,Ma Meng,Shi Yanqin,Wang Xu
Amitrole is reported as a novel kind of transparent poly(vinyl chloride) (PVC) thermal stabilizer that has both excellent inhibition of “zinc burning” thermal stability and antibacterial ability in this paper, which provide the possibility of applying the whole PVC industry into medical and food packaging, artificial leather, wire and cable, indoor decoration, and so on. From the results of Congo red test, discoloration test, and dynamic thermal stability test, we could clearly find out that amitrole could effectively replace the unstable chlorine atom and inhibit “zinc burning” of transparent PVC, while the long-term stability should be improved. Next, the stabilization mechanism of amitrole was also confirmed. The antibacterial activity of amitrole was measured by the bacteriostatic ring experiments. It was observed that the PVC films had good antibacterial properties after modified by amitrole. At last, optimal design of the amitrole/ZnSt 2 (1:1)/ESBO formulation was studied, which have strong potential as thermal stabilizer to prepare super transparency and antibacterial PVC resin.
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高影响因子
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