SOLID STATE IONICS
·
2019
·
IF 2.886
Jiang Zhou,Dongyun Zhang,Guanghan Sun,Chengkang Chang
Lithium-iron phosphate (LiFePO 4 ) monocrystalline platelets (LFP-P) with ac facet-preferred growing were obtained by a solvothermal method . Based on its anisotropy, a LiFePO 4 cathode (LFP-PM) with the b axis-oriented aligning was prepared by magnetic orientation. The structure, morphology and magnetic performance of the LFP-P were studied by X-ray diffractometry, scanning-electron microscopy, transmission-electron microscopy and superconducting quantum-interference device technologies. The LFP-P exhibited paramagnetic behavior and its b axis had the largest magnetic susceptibility , which made the LFP-P stack parallel to the magnetic field . It resulted in a higher lithium-ion diffusion coefficient of the LFP-PM (1.6855 × 10 −11 cm 2 s −1 ) compared with that of the LiFePO 4 cathode (LFP-PU) prepared without magnetic orientation (1.2538 × 10 −11 cm 2 s −1 ). The faster lithium-ion diffusion was contributed to a higher reversibility at 0.1 mV s −1 and higher discharge capacities of the LFP-PM at high rates ≥2 C. For the first time, LiFePO 4 monocrystalline platelets were made to align along b axis through magnetic orientation. It was proved to be an effective means of enhancing high rate performance.
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Jie Chen,Baoquan Xiao,Changfa Hu,Hangda Chen,Juanjuan Huang,De Yan,Shanglong Peng
VO2 (B) electrode material has relatively high capacity and good cycle stability. However, its poor rate performance limits its further development because of the strong interaction between zinc ions and the main lattice of VO2 (B). Herein, considering the design principle of rate performance improvement, we furnished a different scheme from a previous multistep method of the synthesis–modification strategy of pure VO2 (B). VO2@V2C 1D/2D heterostructure was constructed by controllable partial oxidation of V2C by a one-step hydrothermal method. The unique 1D/2D heterostructure improves diffusivity and reduces the diffusion size of zinc ions at the same time, which significantly improved the rate performance of VO2. The situation at the heterostructure interface is analyzed by Raman spectroscopy, X-ray photoelectron spectroscopy, and ultraviolet photoelectron spectroscopy. Combined with cyclic voltammetry, electrochemical impedance spectroscopy, and galvanostatic intermittent title technology tests, the promotion mechanism for the rate performance of the derived VO2 is further explained. In addition, it is found that V2C MXene can be electrochemically activated when the voltage reaches 1.24 V. By further widening the voltage window to activate V2C, VO2@V2COx heterostructure was obtained, which realizes high capacity and maintains high rate performance in aqueous zinc-ion batteries. This work provides key insights for the design of high-rate-performance electrode materials for aqueous zinc-ion batteries.
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高影响因子
Food Analytical Methods
·
2022
·Vol. 15
·期 12
·3379-3389
·
IF 3.498
Wang Jiamin,Zhou Wenyuan,Gao Lu,Yang Zhenquan,Yang Zhanjun,Chen Dawei,Gao Yajun
In this paper, we have developed a fast and low-cost label-free electrochemical immunosensor for detection of Lactobacillus rhamnosus GG (LGG). The proposed sensor is based on a glassy carbon electrode modified with Cu@Cu 2 O nanoparticles anchored B, N co-doped porous carbon (BNPC) composite. The copper-derived nanoparticles with multiple valence states undergo dramatic changes in surface areas, conductivity, and actives sites due to their combination with BNPC, resulting in enhanced electrochemical performance. In the amperometric immunoassay, the immune complex of antigen and antibody inhibits the transfer of electrons on the electrode interface, causing a change in the current. Thus the quantitative detection of LGG is achieved. Differential pulse voltammetry (DPV) was performed at a LGG concentration of 10 2 to 10 8 colony-forming units CFU mL −1 . The immunosensor showed a good linear relationship between the decrease in peak current and the concentration of LGG ( R 2 = 0.9934), with a short detection time and a detection limit of 12 CFU mL −1 . In short, we have developed a highly sensitive electrochemical immunosensor for the specific detection of LGG using the current-mode, label-free immunoassay method evaluated in this study, providing a reliable mean for quantifying probiotics.
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高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Shihai Miao,Xulong Lv,Xihui Shan,Yi Zhang,Yanjie Liang
Discovering multifunctional luminescent materials to meet the demands of modern spectroscopy is of great significance. However, it is a standing challenge to enable multiple luminescence properties in a single material system via single metal ion doping. Here, we report the inherently Bi3+/Bi2+ codoped Ca3Ga2Ge3O12 persistent phosphor where Bi3+ is in situ reduced to Bi2+. This phosphor can act as an efficient multimodal luminescence material, which simultaneously exhibits long-lasting (>12 h) ultraviolet-B (UVB) and near-infrared (NIR) dual-band persistent luminescence after irradiation by 254 nm ultraviolet (UV) light. UVB and NIR afterglow are ascribed to the distinct Bi3+ and Bi2+ emitters, respectively, proven by comprehensive spectroscopic investigations including X-ray absorption near-edge structure spectra and X-ray photoelectron spectroscopy. Besides, this phosphor also exhibits exceptional photochromic features, accompanied by a rapid body color transformation from white to brown in response to 254 nm UV light within 60 s and excellent recovery capacity upon thermal or blue/white light stimulation. The combination of UVB persistent luminescence of Bi3+ and NIR afterglow of Bi2+ coupled with reversible white-to-brown photochromism phenomenon offers one type of promising multifunctional luminescence material, showing potential to be used for optical storage and anti-counterfeiting applications.
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高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2019
·Vol. 19
·期 9
·5723-5728
·
IF 1.093
Qiu Linlin,Chu Zhudan,Yang Shuli,Chen Yue,Song Lixin,Du Pingfan,Xiong Jie
Basalt fibers loaded with titanium dioxide (BFs/TiO2) were successfully fabricated via a simple and cost effective microwave hydrothermal method. The morphology and structure of the BFs/TiO2 were characterized by transmission electron microscopy, scanning electron
microscopy, and X-ray diffraction. The photocatalytic activity of the BFs/TiO2 was validated by the photodegradation test of Rhodamine B (RhB) under ultraviolet light irradiation. The photocatalytic reaction result revealed the excellent photocatalytic activity of the BFs/TiO2,
with 94% of RhB decomposed at 5 h after irradiation. Furthermore, the recycling test indicated that the BFs/TiO2 exhibited excellent recyclability with photocatalytic degradation rate still maintained at 86% in the fifth cycling test.
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高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Guangchang Yang,Shenglong Yang,Feiyan Lai,Chunlei Tan,Jia Qiao,Hongqiang Wang,Qianqian Jin,Xiaohui Zhang
Current research has found the amorphous/crystal interface has some unexpected electrochemical behaviors. This work designed a surface modification strategy using NaBH4 to induce in situ conversion of the surface structure of Ni-rich LiNi0.8Co0.1Mn0.1O2 (NCM811) into TM-B-O amorphous interface layer. Oxidizing the surface from transition metals (TM) with high valence and reductive BH4– in a weak polar medium of ethanol results in an easy redox reacton. A TM-B-O amorphous structure is formed on NCM811 surface. The action of reactive wetting ensures a complete and uniform structure evolution of the surface crystals. The complete coverage protects the outer crystal and the heterogeneous interface impedance between the modified layer and bulk is reduced. More importantly, this amorphous interface layer through in situ conversion enhances the heterogeneous link at interface and its own structural stability. The modified NCM811 (TB2@NCM) treated with 1 wt % NaBH4 shows excellent electrochemical performance, especially cyclic stability. At a high cutoff voltage of 4.5 V, the capacity retention was 72.5% at 1 C after 500 cycles. The electrode achieves 173.7 mAh·g–1 at 10 C. This work creates a modifying strategy with potential application prospect due to simple technology with low-cost raw material under mild operating conditions.
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高影响因子
Molecular Biomedicine
·
2025
·Vol. 6
·期 1
·1-18
·
IF 10.1
Yao Yu,Liu Yu-ying,Li Jian-feng,Chen Yun-shuo,Shi Lei,Shen Yang,Yang Li-li,Yang Qing
Acute myeloid leukemia (AML), the most common leukemia in adults, exhibits immune escape characteristics like solid tumors. The expression of indoleamine 2,3-dioxygenase 1 (IDO1), a well-recognized immune checkpoint, has been detected in AML blast cells and is associated with poor clinical outcome. Although an imbalance of B cell subpopulations exists in AML patients’ bone marrow microenvironment, the role of B cells and their interaction with IDO1 in AML have yet to be elucidated. Herein, with bioinformatic analysis, we found the close correlations between IDO1 expression and survival and B cell subpopulation proportions in AML patients. Further, our investigation into IDO1 expression and activity, B cell subpopulation proportions and immunosuppressive interleukin-10 (IL-10) level in AML cells and clinical samples revealed significant findings. Using a co-culture system of healthy human PBMCs and AML cell lines, we demonstrated that high IDO1 expression in AML cells could alter the proportions of total B, regulatory B and memory B cells, and increased the level of IL-10. Finally, with the IDO1 inhibitor RY103 designed by our laboratory, we found that IDO1 inhibition had good anti-leukemic effect and restored the abnormal proportions of B cell subpopulations in AML mice. Our study is the first to reveal the modulation of IDO1 on B cell subpopulations in AML, making a significant breakthrough in understanding the immune escape mechanisms of AML. Application of IDO1 inhibitor, such as RY103, targeting the imbalance of B cell subpopulations can lead to innovative treatments for AML.
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产品关联
DOI
PubMed
高影响因子
Journal of Environmental Sciences
·
2025
·
IF 6.3
Rong Wang,Weikun Zhu,Jiayi Hu,Siyang Liao,Cheng Chen,Baihang Chen,Shaobin Huang,Jiangyao Chen
Bismuth-based photocatalyst has garnered significant attention for degrading dyes and antibiotics in wastewater. However, their photocatalytic performance remains limited due to the high recombination rate of photoinduced carriers. Constructing a bismuth-based photocatalyst with high-efficiency and rapid degradation performance is crucial for its practical application. In this study, BiOBr nanosheets, with an ultra-thin structure and abundant (001) facet exposure, exhibiting stable photoelectric conversion ability, were successfully synthesized through a simply solvothermal method. Under simulated solar light irradiation, the catalyst achieved 100 % degradation of rhodamine B within 5 min and 97.6 % degradation of tetracycline within 30 min, while over 90 % degradation efficiency after 5 cycles was preserved, demonstrating high, rapid and stable performance of the catalyst. Moreover, 90.7 % and 44.5 % of removal and mineralization efficiencies for TC within 30 min were observed under natural sunlight irradiation. Superoxide radicals and photo-generated holes were the primary species responsible for the degradation of pollutants and the former contributed more effect in long reaction time. Finally, a possible photocatalytic oxidation pathway of tetracycline was proposed based on identified five main intermediates. The BiOBr nanosheets catalyst exhibits great potential for industrial applications in the elimination of hazardous and difficult-to-degrade organic pollutants in wastewater.
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产品关联
DOI
高影响因子
Carbon Letters
·
2025
·
IF 5.8
Du Xue,Han Tong,Jin Biao,Meng Long-Yue,Han Lian-Hua
Contamination of food with heavy metal ions and nitrites poses a serious threat to human health. Consequently, the development of fast and sensitive platforms for detecting these contaminants is urgently required. In this paper, a novel MnMgFe-LDHs/DC sensor is constructed based on a simple strategy, in which MnMgFe layered double hydroxide (LDHs) is used as a metal precursor, and a unique "island bridge" carbon network structure is generated by its pyrolysis with ZIF-8@B, N-WMCNTs. The electrical conductivity was enhanced, and a large electroactive surface area was provided for the MnMgFe-LDHs/DC. The electrochemical properties of Pb 2+ , Cd 2+ and nitrite were investigated using this electrode as a working electrode. Under optimized conditions, the sensing platform exhibited a wide linear range with the Pb 2+ , Cd 2+ , and NO 2 − limits of detection of 46.16 nM, 59.25 nM, and 0.083 μM, respectively. Of particular note is that this sensing platform exhibits outstanding anti-interference capabilities. It can precisely and efficiently conduct the detection of nitrite and heavy metal ions in pickled foods.
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高影响因子
ACS Applied Materials & Interfaces
·
2017
·
IF 7.504
Zelun Zhi,Yajuan Su,Yuewei Xi,Liang Tian,Miao Xu,Qianqian Wang,Sara Padidan,Peng Li,Wei Huang
In recent years, microbial colonization on the surface of biomedical implants/devices has become a severe threat to human health. Herein, surface-immobilized guanidine derivative block copolymers create an antimicrobial and antifouling dual-functional coating. We report the preparation of an antimicrobial and antifouling block copolymer by the conjugation of polyhexanide (PHMB) with either allyl glycidyl ether or allyloxy polyethylene glycol (APEG; MW 1200 and 2400). The allyl glycidyl ether modified PHMB (A-PHMB) and allyloxy polyethylene glycol1200/2400 modified PHMB (APEG1200/2400-PHMB) copolymers were grafted onto a silicone rubber surface as a bottlebrush-like coating, respectively, using a plasma-UV-assisted surface-initiated polymerization. Both A-PHMB and APEG1200/2400-PHMB coatings exhibited excellent broad-spectrum antimicrobial properties against Gram-negative/positive bacteria and fungi. The APEG2400-PHMB coating displayed an improved antibiofilm as well as antifouling properties and a long reusable cycle, compared with two other coatings, due to its abundant PEG blocks among those copolymers. Also, the APEG2400-PHMB-coated silicone coupons were biocompatible toward mammalian cells, as revealed by in vitro hemocompatibile and cytotoxic assays. An in vivo study showed a significant decline of Escherichia coli colonies with a 5-log reduction, indicating the APEG2400-PHMB coating surface worked effectively in the rodent subcutaneous infection model. This PHMB-based block copolymer coating is believed to be an effective strategy to prevent biomaterial-associated infections.
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DOI
PubMed
高影响因子
MOLECULES
·
2018
·Vol. 23
·期 12
·3083
·
IF 3.098
Xiaojian Ouyang,Xican Li,Wenbiao Lu,Xiaojun Zhao,Dongfeng Chen
To clarify the role of theB-ring in antioxidant flavonols, we performed a comparative study between galangin with a nullB-ring and 3,5,7-trihydroxychromone without aB-ring using five spectrophotometric assays, namely,•O2−-scavenging, 1,1-diphenyl-2-picrylhydrazyl radical (DPPH•)-scavenging, 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide radical-scavenging, 2,2′-azino-bis(3-ethylbenzo-thiazoline-6-sulfonic acid) radical-scavenging, and Fe3+-reducing activity. The DPPH•-scavenging reaction products of these assays were further analyzed by ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry (UPLC-ESI-Q-TOF-MS/MS) technology. In the five spectrophotometric assays, galangin and 3,5,7-trihydroxychromone dose-dependently increased their radical-scavenging (or Fe3+-reducing) percentages. However, galangin always gave lower IC50values than those of 3,5,7-trihydroxychromone. In the UPLC-ESI-Q-TOF-MS/MS analysis, galangin yielded galangin-DPPH adduct MS peaks (m/z662, 434, 301, 227,196, and 151) and galangin-galangin dimer MS peaks (m/z538, 385, 268, 239, 211, 195, and 151). 3,5,7-Trihydroxychromone, however, only generatedm/z3,5,7-trihydroxychromone-DPPH adduct MS peaks (m/z586, 539, 227, 196, and 136). In conclusion, both galangin and 3,5,7-trihydroxychromone could similarly undergo multiple antioxidant pathways, including redox-dependent pathways (such as electron transfer (ET) and ETplusproton transfer (PT)) and a non-redox-dependent radical adduct formation (RAF) pathway; thus, the nullB-ring could hardly change their antioxidant pathways. However, it did improve their antioxidant levels in these pathways. Such improvement of theB-ring toward an antioxidant flavonol is associated with its π-π conjugation, which can provide more resonance forms and bonding sites.Keywords:antioxidant;galangin;3,5,7-trihydroxychromone;flavonol;structure–activity;B-ring
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DOI
PubMed
高影响因子
ARCHIV DER PHARMAZIE
·
2022
·Vol. 355
·期 7
·2100465
·
IF 4.613
Yating Guo,Xiaoding Jiang,Qi Chang,Zhihong Xiao,Zhuo Chen,Dejian Jiang,Gaoyun Hu,Qianbin Li
A series of novel pyrazolo[3,4- b ]pyridine derivatives were designed, synthesized, and biologically evaluated for anti-lung cancer activity. Structure–activity relationship and AutoGPA models were constructed based on the in vitro antiproliferative potency of the compounds against a human lung adenocarcinoma cell line (A549). Compound 9d exhibits improved potency for A549 cell growth inhibition (3.06 ± 0.05 μM) compared with A-769662 (45.29 ± 2.14 μM). Compound 9d can elevate the phosphorylation levels of adenosine monophosphate-activated protein kinase (AMPK) and its substrate acetyl-CoA carboxylase and reduce the level of phosphorylated ribosomal S6 kinase (p-70S6K) at 1 μM, which is comparable to the activity of A-769662 at 20 μM. 9d induced G2/M cell cycle arrest, which was rescued when co-incubated with “Compound C,” a potent AMPK inhibitor. Taken together, compound 9d showed potential anti-lung cancer activity via inducing cell cycle arrest by regulation of the AMPK/70S6K pathway in A549 cells, which could provide a new lead for the discovery of anti-lung cancer agents.
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PubMed
高影响因子
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