Foods
·
2021
·Vol. 10
·期 2
·419
·
IF 4.35
Pei Hu,Zhentao Sun,Yunwen Shen,Yiwen Pan
Hydrogen peroxide (H2O2) has been reported to be used for the illegal treatment of fishery products in order to obtain “fake” freshness. Residues of H2O2in food may be of toxicology concern. In this study, a nonenzymatic sensor was developed based on Fe@PCN-224 metal–organic frameworks wrapped by Nafion to detect H2O2concentration. The hybrid structure of Fe@PCN-224 was fabricated by incorporated free FeIIIions into the center of PCN-224, which was ultra-stable due to the strong interactions between Zr6and the carboxyl group. Scanning electron spectroscopy images exhibited that Nafion sheets crossed together on the surface of Fe@PCN-224 nanoparticles to form a hierarchical and coherent structure for efficient electron transfer. Electrochemical investigations showed that the Fe@PCN-224/Nafion/GCE possessed good linearity from 2 to 13,000 μM (including four orders of magnitude), low detection limits (0.7 μM), high stability in continuous monitoring (current remained nearly stable over 2300 s) and in long-term measurement (current decreased 3.4% for 30 days). The prepared nanohybrid modified electrode was effectively applied to H2O2detection in three different fishery products. The results were comparable to those measured using photometrical methods. The developed electrochemical method has a great potential in detecting the illegal management of fishery products with H2O2.Keywords:Fe@PCN-224;Nafion;nonenzymatic sensor;hydrogen peroxide;fishery products
研究领域:
食品安全检测
·
电化学分析
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 118
·97648-97657
·
IF 3.84
Cong Wu,Guangmei Xia,Jing Sun,Rui Song
With dopamine as a reducing and sticking agent, triblock copolymer poly(ethylene oxide)–poly(propylene oxide)–poly(ethylene oxide) (PEO–PPO–PEO), Pluronic F127, was employed to immobilize and stabilize silver nanoparticles (Ag NPs) by the chemical reduction of silver nitrate, AgNO3. Thus, a ternary system comprising Ag NPs, dopamine and F127, i.e. a Ag@DA@F127 system was constructed. In this ternary system, Ag NPs were anisotropically self-assembled and uniformly dispersed in network-like F127 micelles. As evidenced the dispersion stability of Ag NPs in this system was significantly enhanced compared to the Ag@DA and Ag@NaBH4@F127 system, which in turn resulted in a more sensitive and quantitative detection of H2O2. Further investigation demonstrated that the Ag@DA@F127 system exhibited a UV-vis absorption band at ∼405 nm and the intensity of this absorption band dramatically decreased linearly over the concentration range of 0.1–100 μM H2O2 (r2 = 0.99056), deriving a detection limit of 33 nM, which was superior to recent reports. Apart from its excellent performance in H2O2 detection, this Ag@DA@F127 system has other benefits including facile and simple, being environmentally friendly, and especially the formation of a specific network-like structure to fully disperse Ag NPs, which makes it practical in H2O2 detection.
研究领域:
材料科学
·
分析化学
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DOI
高影响因子
JOURNAL OF FOOD PROTECTION
·
2021
·
IF 2.077
Bing Han,Xiaoyu Han,Mengmeng Ren,Yilin You,Jicheng Zhan,Weidong Huang
ABSTRACT Diseases caused by harmful microorganisms pose a serious threat to human health. Safe and environmentally friendly disinfectants are, therefore, essential in preventing and controlling such pathogens. This study aimed to investigate the antimicrobial activity and mechanism of a novel hydrogen peroxide and silver (H 2 O 2 -Ag + ) complex (HSC) in combatting Staphylococcus aureus ATCC 29213, Escherichia coli O157:H7 NCTC 12900, and Salmonella Typhimurium SL 1344. The MICs and MBCs against S. aureus were found to be 0.014% H 2 O 2 –3.125 mg/L Ag + , and for both E. coli O157:H7 and Salmonella Typhimurium they were 0.028% H 2 O 2 –6.25 mg/L Ag + . Results of the time-kill trial suggest that HSC could inhibit the growth of the tested bacteria, because 99.9% of viable cells were killed following treatment at 1 MIC for 3 h. The mechanism of antibacterial action of HSC was found to include the disruption of the bacterial cell membrane, followed by reduction of intracellular ATP concentration and inhibition of the activity of antioxidases, superoxide dismutase, and catalase. The enhanced bactericidal effect of hydrogen peroxide combined with silver indicates a potential for its application in environmental disinfection, particularly in the food industry.
研究领域:
微生物学
·
环境科学
·
食品科学
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DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2019
·Vol. 30
·期 4
·1907071
·
IF 15.621
Shaojie Dong,Yu Chen,Luodan Yu,Kaili Lin,Xudong Wang
Chemotherapy resistance and bone defects caused by surgical excision of osteosarcoma have been formidable challenges for clinical treatment. Although recently developed nanocatalysts based on Fenton-like reactions for catalytic therapy demonstrate high potential to eliminate chemotherapeutic-insensitive tumors, insufficient concentration of intrinsic hydrogen peroxide (H 2 O 2 ) and low intratumoral penetrability hinder their applications and therapeutic efficiency. The synchronous enriching intratumor H 2 O 2 amount or nanoagents and promoting osteogenesis are intriguing strategies to solve the dilemma in osteosarcoma therapy. Herein, a multifunctional “all-in-one” biomaterial platform is constructed by co-loading calcium peroxide (CaO 2 ) and iron oxide (Fe 3 O 4 ) nanoparticles into a three-dimensional (3D) printing akermanite scaffold (AKT-Fe 3 O 4 -CaO 2 ). The loaded CaO 2 nanoparticles act as H 2 O 2 sources to achieve H 2 O 2 self-sufficient nanocatalytic osteosarcoma therapy as catalyzed by coloaded Fe 3 O 4 nanoagents, as well as provide calcium ion (Ca 2+ ) pools to enhance bone regeneration. The synergistic osteosarcoma-therapeutic effect is achieved from both magnetic hyperthermia as-enabled by Fe 3 O 4 nanoparticles under alternative magnetic fields and hyperthermia-enhanced Fenton-like nanocatalytic reaction for producing highly toxic hydroxyl radicals. Importantly, the constructed 3D AKT-Fe 3 O 4 -CaO 2 composite scaffolds are featured with favorable bone-regeneration activity, providing a worthy base and positive enlightenment for future osteosarcoma treatment with bone defects by the multifunctional biomaterial platforms.
研究领域:
生物医学工程
·
纳米技术
·
肿瘤学
·
材料科学
·
再生医学
✓ 已验证
DOI
高影响因子
Biomolecules
·
2022
·Vol. 12
·期 9
·1237
·
IF 6.064
Fei-Fei Yu,Yao Yuan,Yan Ao,Li Hua,Wu Wang,Yiyi Cao,Jing Xi,Yang Luan,Shangwei Hou,Xin-Yu Zhang
Bilirubin (BR) is a tetrapyrrolic compound stemming from heme catabolism with diverse physiological functions. It can be oxidized by H2O2to form several degradation products, some of which have been detected in vivo and may contribute to the pathogenesis of certain diseases. However, the oxidative degradation of BR is complex and the conditions that BR degradation occurs pathophysiologically remain obscure. Neutrophils are known to generate large amounts of reactive oxygen species, including H2O2, upon activation and they are mobilized to inflammatory sites; therefore, we hypothesized that activated neutrophils could cause BR degradation, which could occur at inflammatory sites. In the present study, we investigated BR degradation by H2O2and identified hematinic acid (BHP1) and a new product BHP2, whose structure was characterized as 2,5-diformyl-4-methyl-1H-pyrrole-3-propanoic acid. An LC-MS/MS method for the quantitation of the two compounds was then established. Using the LC-MS/MS method, we observed the concentration-dependent formation of BHP1 and BHP2 in mouse neutrophils incubated with 10 and 30 μM of BR with the yields being 16 ± 3.2 and 31 ± 5.9 pmol/106cells for BHP1, and 25 ± 4.4 and 71 ± 26 pmol/106cells for BHP2, respectively. After adding phorbol 12-myristate 13-acetate, a neutrophil agonist, to 30 μM of BR-treated cells, the BHP1 yield increased to 43 ± 6.6 pmol/106cells, whereas the BHP2 one decreased to 47 ± 9.2 pmol/106cells. The two products were also detected in hemorrhagic skins of mice with dermal inflammation and hemorrhage at levels of 4.5 ± 1.9 and 0.18 ± 0.10 nmol/g tissue, respectively, which were significantly higher than those in the non-hemorrhagic skins. BHP2 was neurotoxic starting at 0.10 μM but BHP1 was not, as assessed usingCaenorhabditis elegansas the animal model. Neutrophil-mediated BR degradation may be a universally pathophysiological process in inflammation and can be particularly important under pathological conditions concerning hemorrhage.Keywords:bilirubin;hydrogen peroxide;degradation;neutrophil;inflammation;hemorrhage
研究领域:
生物化学
·
免疫学
·
病理生理学
✓ 已验证
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2026
·
IF 6.6
Guangyuan Chen,Qina Quan,Chenyang Lin,Shijian Zhou,Yan Kong
Tetracycline (TC), as a persistent and widely detected antibiotic pollutant, poses severe ecotoxicological risks and necessitates rapid and efficient degradation strategies. Here, we demonstrate a photocatalytic self-Fenton process in which H 2 O 2 produced via visible-light-driven oxygen reduction is directly activated by Fe species for the rapid degradation of TC. To enable efficient H 2 O 2 production, a ternary ZnIn 2 S 4 / CdIn 2 S 4 /MnIn 2 S 4 (denoted as ZC 0.3 M 0.05 ) heterojunction photocatalyst was rationally constructed via a one-pot hydrothermal method. Structural analyses reveal that the three sulfides form a tightly coupled, multi-interfacial nanoscale architecture that induces pronounced interfacial strain and charge polarisation. Consequently, ZC 0.3 M 0.05 delivers a high H 2 O 2 production rate of 4907.7 μmol g⁻ 1 h⁻ 1 , outperforming pristine ZnIn 2 S 4 , CdIn 2 S 4 and MnIn 2 S 4 by factors of 15.2, 10.7 and 13.6, respectively. Upon Fe addition, the in situ generated H 2 O 2 enabled rapid self-Fenton degradation of TC, achieving 91.9 % removal within 5 min, while maintaining high activity under simulated environmental conditions. Combined spectroscopic, electrochemical and theoretical analyses reveal that work-function-difference-driven and stepwise electron-transfer pathways (MnIn 2 S 4 → ZnIn 2 S 4 → CdIn 2 S 4 ) across multiple heterointerfaces facilitate efficient charge separation and O 2 -to-*O 2 ⁻ electron injection. This work establishes a materials framework for on-demand H 2 O 2 production and direct self-Fenton pollutant remediation, and offers general design principles for high-performance ternary metal sulfide heterojunctions.
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产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2026
·
IF 6.3
Jinqiu Zhuo,Wenwen Lv,Zixin Li,Yaodan Cao,Bingbing Li,Yusen Huangfu,Yuchun Zhang,Jiaxu Zhang,Jie Wu
Molten salt method was effective to improve the photocatalytic performance of graphitic carbon nitride (CN). Nevertheless, various complex reactions took place in flux, leading to the complicated CN molecular structure. Therefore, besides high photoactivity, it was necessary to illustrate the structure-function relationship. Herein, CN nanosheets (CN-S) were prepared. After post-treated by LiCl molten salts, the photocatalytic H 2 O 2 rate over as-obtained CN-S-LiCl- x was dramatically increased from 22.3 to 81.4 mM·g −1 ·h −1 , much higher than the sample post-treated by NaCl and KCl molten salts. Compared to the initial CN-S, the -C N groups, bulk N-defects and surface N-defects were controllably introduced in CN-S-LiCl- x. These critical structural factors on photocatalytic H 2 O 2 performance were quantitatively studied, and the bulk N-defects displayed the correlation of linear relationship as high as 0.945. Electrochemical tests and DFT calculation indicated bulk N-defects were served as the main O 2 adsorption sites with adsorption energy of −4.33 eV, which not only accelerated surface reaction, but also extended light harvest and improved separation efficiency of photoinduced charge carriers. In photocatalytic H 2 O 2 mechanism study, one-step two-electron reduction and two-step single-electron reduction performed simultaneously, while the latter was primary. Our work has conducted a detailed analysis on the relationship between various structural factors and H 2 O 2 yield, and identified the key role of bulk N-defects. This provides new ideas to investigate photocatalytic H 2 O 2 evolution mechanism and design efficient CN-based photocatalysts.
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产品关联
DOI
高影响因子
Environmental Science-Advances
·
2022
·Vol. 2
·期 1
·98-106
·
IF 0
Jingzhen Zhang,Qian Zheng,Chen Chen,Xiangcheng Zhang,Xiaoyan Guo,Mingce Long
A self-maintainable decentralized water treatment system is appealing, while avoiding chemical addition is the prerequisite to realize it. As a widely used chemical in advanced oxidation processes (AOPs), H2O2 can be produced via photocatalysis. However, there remain challenges to use the photocatalytically produced H2O2 for water purification in a continuous operation, which requires that the produced H2O2 solution has no impurity and the catalyst powder is easily separable. We realized this by photocatalytic H2O2 production over magnetic separable photocatalytic microspheres through a sequencing batch process and coupling with ultraviolet C (UVC)/H2O2 for micropollutant removal via a flow-through operation. The photocatalysts were synthesized by in situ growth of a resorcinol–formaldehyde (RF) copolymer on Fe3O4@SiO2 microspheres, which can convert earth-abundant water and air into H2O2 under visible light irradiation. A clean H2O2 solution was produced at 100 μmol h−1 g−1 over magnetic photocatalysts and separated by using an external magnetic field. The on-site utilization of the obtained H2O2 solution was realized via UV light irradiation. This work provides a rational design of easily separable photocatalysts for H2O2 production, and offers insights for development of water purification processes with zero chemical addition and maintenance.
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
DOI
ANALYST
·
2022
·Vol. 147
·期 23
·5324-5333
·
IF 5.227
Jie Zhang,Xue-Ji Zhang,Serge Cosnier,Dan Shan
In the rapid development of artificial nanomaterials comparable to biological enzymes, we propose herein a novel concept for the construction of functional materials inspired from chemical evolution. To mimic the formation process of the catalytic system for the origin of life, dicyandiamide (DCD) was used as an elemental molecule for the de novo synthesis of an electrocatalyst. DCD was initially condensed with glucose (Glu) to form carbon dots (CDs) via a hydrothermal method. The self-assembly of the DCD-derived CDs was then modulated by introducing copper ions and a controlled pyrolysis process. Carbonization of the self-organized DCD-CDs/Cu at 300 °C in air produced the resultant catalyst (DCD-CDs/Cu-300) with the crystalline properties of a transitional state from an organic to inorganic matter, possessing a well-tuned chemical composition and the enhanced electrochemical signal of H2O2 reduction. Therefore, the DCD-CDs/Cu-300 modified electrode provides satisfactory analytical performance for trace H2O2 quantification with a wider linear range (1.0 × 10−7 to 1.4 × 10−3 M) and low detection limit (6.4 × 10−8 M, S/N = 3). This facile electrocatalyst construction strategy inspired from chemical evolution is expected to pave the way to form a more unified paradigm by integrating nanotechnology.
研究领域:
材料科学
·
分析化学
·
仿生学
✓ 已验证
DOI
高影响因子
Frontiers of Chemical Science and Engineering
·
2024
·Vol. 18
·期 10
·1-10
·
IF 4.3
Jia Hongwei,Yue Xiaoyang,Hou Yuying,Huang Fei,Cao Cuiyao,Jia Feifei,Liu Guanhua,Zheng Xiaobing,Liu Yunting,Jiang Yanjun
Unspecific peroxygenases exhibit high activity for the selective oxyfunctionalization of inert C(sp 3 )-H bonds using only H 2 O 2 as a clean oxidant, while also exhibiting sensitivity to H 2 O 2 concentration. CdS-based semiconductors are promising for the photosynthesis of H 2 O 2 owing to their adequately negative potential for oxygen reduction reaction via a proton-coupled electron transfer process, however, they suffer from fast H 2 O 2 decomposition on the surface of pristine CdS. Therefore, [Cp*Rh(bpy)H 2 O] 2+ , a highly selective proton-coupled electron transfer catalyst, was anchored onto a supramolecular polymer-grafted CdS nanoflower to construct an efficient integrated photocatalyst for generating H 2 O 2 , mitigating the surface issue of pristine CdS, increasing light absorption, accelerating photonic carrier separation, and enhancing oxygen reduction reaction selectivity to H 2 O 2 . This photocatalyst promoted the light driven H 2 O 2 generation rate up to 1345 µmol·L −1 ·g −1 ·h −1 , which was 2.4 times that of pristine CdS. The constructed heterojunction photocatalyst could supply H 2 O 2 in situ for nonspecific peroxygenases to catalyze the C-H oxyfunctionalization of ethylbenzene, achieving a yield of 81% and an ee value of 99% under optimum conditions. A wide range of substrates were converted to the corresponding chiral alcohols using this photo-enzyme catalytic system, achieving the corresponding chiral alcohols in good yield (51%–88%) and excellent enantioselectivity (90%–99% ee).
研究领域:
生物化学
·
材料科学
·
催化化学
✓ 已验证
DOI
高影响因子
TALANTA
·
2026
·
IF 6.7
Chenglong Chen,Qiaoxia Zhang,Xiajuan Wang,Ran Miao,Tiesheng Shi,Qingyun Liu
To resolve the conflict between multidimensional interferences derived from complex matrices and the stringent requirements for trace-level detection sensitivity, a novel electrochemical aptasensor was constructed for highly sensitive kanamycin (KANA) detection based on a split aptamer engineering strategy. Ag–Ti 3 C 2 T x MXene, synthesized via in-situ reduction of silver nanoparticles onto the surface of two-dimensional MXene nanosheets, is employed for electrode decoration. This composite possesses abundant binding sites for aptamer 1 (Apt1) immobilization and exhibits outstanding catalytic performance in the reduction of H 2 O 2 . Signal acquisitions were performed under reductive potential conditions, endowing the sensor with superior anti-interference capability. Upon KANA addition, aptamer 2 (Apt2) can assemble into a ternary structure with the target and Apt1, leading to the displacement of cDNA and triggering a signal-down response. Under optimized conditions, the fabricated aptasensor presents a broad linear range of 1∼20000 nM with a limit of detection (LOD) of 0.12 nM, and exhibits excellent selectivity, reproducibility, and strong stability. In addition, the aptasensor demonstrates satisfactory recovery rates in real sample analysis, indicating its great potential for practical applications. The combination of Ag–Ti 3 C 2 T x MXene nanocomposite and split aptamer engineering technology provides a feasible strategy for highly sensitive detections of trace-level antibiotic residues in complex food matrices.
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DOI
PubMed
高影响因子
Science China-Materials
·
2025
·Vol. 69
·期 1
·215-227
·
IF 7.4
Chen Guangyuan,Tang Tingting,Li Yubao,Lin Chenyang,Zhou Shijian,Kong Yan
Metal sulfides like CdS hold promise for solar-driven H 2 O 2 productions but suffer from rapid charge recombination and severe photocorrosion. This study introduces a dual-functional strategy synergizing sulfur vacancy (S v ) engineering and polydopamine (PDA) coating to overcome these limitations. S v -CdS nanorods were hydrothermally synthesized with tunable vacancy concentrations, followed by in-situ PDA deposition to construct a direct Z-scheme heterojunction. X-ray photoelectron spectroscopy (XPS) and density functional theory (DFT) calculations reveal that the introduction of S vacancies reduces the work function of CdS, facilitating energy level alignment with PDA and enabling efficient electron transfer from CdS to PDA. By tuning the concentration of S vacancies, the charge transfer efficiency can be maximized. As a result, the photocatalytic H 2 O 2 production rate reaches 2539.5 µmol g −1 h −1 under visible light, and further increases to 4395.5 µmol g −1 h −1 after PDA encapsulation —15.6 times higher than that of pristine CdS. Concurrently, PDA enhances O 2 adsorption and protects S v -CdS from photocorrosion. S v -CdS@PDA exhibited superior photostability compared to S v -CdS after three consecutive photocatalytic cycles. Mechanistic studies suggest that the Z-scheme heterojunction effectively separates electron-hole pairs: electrons in the conduction band of CdS reduce O 2 to ·O 2 − , which is subsequently converted to H 2 O 2 , while holes in the valence band of S v -CdS oxidize water to replenish O 2 . This work provides fundamental insights into engineering charge transfer and stability in sulfide-based photocatalysts.
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DOI
高影响因子
危险品化学品经营许可证（带存储）