FOOD RESEARCH INTERNATIONAL
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2018
·
IF 3.52
Jiaqi Li,Sheng Geng,Benguo Liu,Huabin Wang,Guizhao Liang
The β-cyclodextrin (β-CD) can be used to remove bitter taste of protein hydrolysates, which is attributed to its interaction with hydrophobic amino acids included within peptides. But the corresponding mechanism has not been fully clarified. Herein, we systematically investigate the interaction between β-CD and three hydrophobic amino acids involving tryptophan (Trp), tyrosine (Tyr), and phenylalanine (Phe). We prove the formation of amino acid/β-CD supermolecular complexes determined by FS, UV, IR, DSC and NMR, manifesting that no new chemical bond is formed in these complexes. The theoretical interaction conformations are given by molecule docking and further supported by ONIOM (our Own N-layer Integrated Orbital molecular Mechanics) calculations, with the consideration of structural assignments, binding orientations, solvent effects, interaction energies and main forces to form these complexes. Molecular docking results suggest that the hydrophobic amino acids prefer to interact with β-CD by their aromatic ring, meaning hydrophobic interactions are main forces for them entering into the cavity of β-CD. ONIOM-based calculations provide a number of quantum-chemical parameters to confirm our experimental results; meanwhile, to demonstrate that H-bonds play an important role in maintaining the stability of three amino acid/β-CD complexes. This work is help for demonstrating the interaction mechanism of amino acid/β-CD supermolecular system, and guiding how to remove bitterness or undesirable taste of bioactive peptides , even other interested molecules.
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CHEMISTRY AND ECOLOGY
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2018
·
IF 1.091
Tingfeng Liu,Keqiang Ding,Guang Guo,Feng Yang,Lihong Wang
Effect of hydroxypropyl-β-cyclodextrin (HPCD) on the bioavailability and biodegradation of the polycyclic aromatic hydrocarbons (PAHs) pyrene (PYR) and benzo[α]pyrene (BaP) in spiked soils was investigated in 14-week incubation experiments. To evaluate the effect of HPCD in soils with a different matrix, humic substance (HS) was added into soil samples. A 6-h Tenax TA extraction method was used to evaluate pollutants bioavailability. The biodegraded and extracted fractions were compared to evaluate the impact of HPCD on PAHs biodegradation. Results indicated positive effects of HPCD on fast desorption behaviours of PAHs. The biodegraded fraction was consistent with that of the extracted for PYR. However, in terms of BaP, the results were contrary which suggests that biological factors may be limiting factors for BaP pollution remediation. HS weakened the HPCD solubilisation effect while accelerated the decay of PYR and BaP, also implying that bioavailability was not the sole factor limiting PAH biodegradation. In addition, analysis of microbial communities demonstrated that HPCD inhibited the growth of some soil bacteria while HS promoted the evolution of some soil microorganisms. A limited population of hydrocarbon degrader populations led to observing incomplete PAH biodegradation even in the presence of HPCD.
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CARBOHYDRATE POLYMERS
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2018
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IF 5.158
Shuyue Jia,Dongyan Tang,Jing Peng,Zhaojie Sun,Xu Yang
Novel β-cyclodextrin modified fibers with highly insoluble infraction and temperature enhanced adsorption performance were fabricated via electrospinning technology and followed thermo-crosslinking. The fabricated fibers were characterized by FT-IR, 1 H NMR, TGA and SEM. In the fibers, β-CD was crosslinked with methacrylic acid (MAA) units to maintain morphologies of fibers and further be utilized for the adsorption of Crystal Violet through complex and electrostatic interaction. In particular, N -isopropyl acrylamide (NIPAM) units were introduced to create thermo-responsively hydrophobic internal cavity within the swelling fibers at high temperatures. Benefiting from that, the maximum adsorption amount could reach to 1253.78 mg g −1 , enhanced by 20% than that at low temperatures. The adsorption data of the fibers fit well the pseudo-second-order model and Langmuir isotherm model. Moreover, the fibers could maintain high regeneration efficiency even after four adsorption-desorption cycles. These results indicated the practical application values of the β-cyclodextrin modified fibers in the dye wastewater treatment field.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2018
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IF 2.829
Hong-Liu Jiang,Jie-Ci Lin,Wei Hai,Hong-Wei Tan,Yu-Wei Luo,Xiao-Lin Xie,Yao Cao,Fu-An He
In this work, a novel crosslinked porous β-cyclodextrin-based polymer containing carboxylic acid groups (CT-β-CD) was synthesized successfully and characterized by SEM , FTIR, 13 C solid-state NMR, water-contact-angle measurement, and TGA . The resultant CT-β-CD with triple absorption effects including inclusion complextion, porous network capture, and electrostatic interaction was employed as an adsorbent for removing methylene blue dye from aqueous solution, which exhibited several advantages such as high absorption capacity (q max = 672 mg/g), rapid absorption rate, good recyclable ability, and selective adsorption for cationic dyes. The influences of initial MB concentration, absorption time, and pH value on the absorption behavior of CT-β-CD for MB were also investigated. In addition, it was found that the pseudo-second-order kinetic and the Langmuir model for adsorption isotherm could be used to describe the MB absorption behavior of CT-β-CD.
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Journal of Materials Chemistry C
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2018
·Vol. 6
·期 38
·10226-10232
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IF 5.976
M. Yuan,R. Wang,C. Zhang,Z. Yang,W. Cui,X. Yang,N. Xiao,H. Wang,X. Xu
Exploiting new transitions in the visible light range is important in the development of advanced color displays, superior laser materials, and novel optical devices. Here, for the first time, we observed several intensive upconversion (UC) emission bands at 382, 472, 506, 560, and 618 nm from a single β-NaYF4:Yb/Er microcrystal via saturated excitation. Compared to the traditional red (650 nm) and green (545 nm) UC emissions, these new emission bands intensify rapidly as the excitation intensity increases, which leads to full-color UC luminescence in the visible region. Nearly white luminescence was elicited from a single microcrystal with a relatively high excitation power. Moreover, the mechanism of these newly observed UC emissions was elucidated by examining the energy migration. It was also found that these microcrystals exhibit waveguide-transmission characteristics and are transparent to their own UC emissions. These findings provide a basis for further exploration of the silent transitions of other rare-earth-ions and demonstrate the potential for using β-NaYF4:Yb/Er microcrystals in a variety of applications in color display and waveguide-based optical devices.
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ANALYTICAL CHEMISTRY
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2018
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IF 6.042
Baoxia Liu,Haoshuang Shen,Yuanqiang Hao,Xu Zhu,Suzhi Li,Yankai Huang,Peng Qu,Maotian Xu
Metal–organic coordination polymers (MOCPs) have been emerging as very attractive nanomaterials due to their tunable nature and diverse applications. Herein, using Tb3+ as the luminescence center, 1,3,5-benzenetricarboxylate (BTC) as building block and Cu2+ as the signal modulator as well as a recognition unit, we propose a novel and effective lanthanide functionalized MOCP (LMOCP) fluorescent sensor (Cu-BTC/Tb) for amyloid β-peptide (Aβ) monomer, a biomarker for Alzheimer disease (AD). Specifically, Cu-BTC/Tb, created by postsynthesis modification strategy under room temperature, is almost nonemissive due to the quenching effect of Cu2+ in the MOCP, exhilaratingly, the presence of Aβ1–40 triggered a significant emission enhancement of Cu-BTC/Tb assay due to the high binding affinity of Aβ1–40 for Cu2+ and the subsequent suppression of the quenching effect. In the assay, this LMOCP sensor shows high sensitivity with detection limit of 0.3 nM. Due to its capability to eliminate autofluorescence, Cu-BTC/Tb was also applied to the time-gated detection of Aβ1–40 in human plasma with promising results. This work presents a novel strategy for the construction of functional luminescent LMOCP for sensitively turn-on fluorescent sensing of Aβ1–40. We believe the proposed strategy would inspire the development of various LMOCP-based fluorescent assays or medical imaging platforms for advanced biological implementations.
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BIOSENSORS & BIOELECTRONICS
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2018
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IF 8.173
Yaoguang Wang,Dawei Fan,Guanhui Zhao,Jinhui Feng,Dong Wei,Nuo Zhang,Wei Cao,Bin Du,Qin Wei
An ultrasensitive label-free photoelectrochemical (PEC) immunosensor with high visible-light activity was developed for quantitative detection of amyloid β-protein (Aβ) by cross-linking anti-Aβ antibody onto the Ag 2 S sensitized SnO 2 /SnS 2 nanocomposites . Specifically, SnO 2 with flower-like porous nanostructure was innovatively applied in PEC immunosensor as a basal material. It could form a heterostructure with SnS 2 , which brought about the sensitization of SnO 2 and enhanced the separation of photogenerated electrons and holes. Moreover, Ag 2 S was in-situ growth on the surface of SnO 2 /SnS 2 , which further enhanced the photocurrent response significantly. Therefore, SnO 2 /SnS 2 /Ag 2 S could form stepwise band-edge structure, which benefited the light harvesting and provided a good foundation for sensor construction and detection. Under optimal conditions, the PEC immunosensor was used to detect the content of Aβ and exhibited a wide linear concentration range from 0.5 pg mL −1 to 100 ng mL −1 , with low limit of detection (0.17 pg mL −1 ) and limit of quantification (0.56 pg mL −1 ). Additionally, the designed PEC immunosensor exhibited good reproducibility, specificity, and stability which may find potential applications in the biosensor, biomedicine , clinical diagnosis, photocatalysis and other related fields.
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Nanomaterials
·
2018
·Vol. 8
·期 9
·724
·
IF 3.504
Bingkai Han,Meixin Pan,Jiexin Zhou,Yingying Wang,Zihua Wang,Jun Jiao,Cong Zhang,Qiang Chen
The use of graphene has leapt forward the materials field and the functional modification of graphene has not stopped. In this work, β-lactoglobulin (BLG) was used to functionalize reduced graphene oxide (RGO) based on its amphiphilic properties. Also, trimetallic PtAuPd nanoparticles were reduced to the surface of BLG-functionalized RGO and formed BLG-PtAuPd-RGO nanocomposite using facile synthesis. Transmission electron microscopy, energy-dispersive X-ray spectroscopy and Fourier transform infrared spectra were used to characterize the nanocomposite. Electrocatalytic analysis was evaluated through cyclic voltammetry and chronoamperometry methods. We developed a glucose sensor by fabricating GOD-BLG-PtAuPd-RGO/glassy carbon (GC) electrode. It presented a remarkable sensitivity of 63.29 μA mM−1cm−2(4.43 μA mM−1), a wider linear range from 0.005 to 9 mM and a lower detection limit of 0.13 μM (S/N = 3). Additionally, the glucose sensor exhibited excellent testing capability in human serum samples.Keywords:graphene;β-lactoglobulin;PtAuPd alloy;electrochemical sensing;glucose sensor
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Food Analytical Methods
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2018
·Vol. 12
·期 3
·697-704
·
IF 2.245
Cui Beijiao,Liu Haiyan,Yu Huan,Pang Xiaoya,Yan Hongyuan,Bai Ligai
In this paper, a hybrid monolithic column with modified nanodiamond and 1-dodecene as co-monomers was prepared and applied to the online enrichment and purification of β-sitosterol in edible oil. The obtained monolithic column was characterized by scanning electron microscopy (SEM) and nitrogen adsorption–desorption isotherm measurement, which indicated that the monolith possessed characteristics of porous structure and high permeability. Under the optimum conditions for extraction and determination, the linear regression coefficient for β-sitosterol was 0.998; the limit of detection (LOD) and the limit of quantitation (LOQ) were 3.0 μg mL −1 and 10.0 μg mL −1 , respectively; the relative standard deviation (RSD) of intra-day and inter-day assays for four edible oils were 2.33–6.58% and 3.24–6.94%, respectively. The recovery was in the range of 89.6–105.5%. The results showed that the hybrid monolithic column with high selectivity and good permeability were successfully used as online solid-phase extraction (SPE) column for determination of β-sitosterol in edible oil.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2019
·
IF 4.084
Tingwei Zhang,Yijuan Lu,Wenzhi Li,Mingxue Su,Tao Yang,Ajibola Ogunbiyi,Yongcan Jin
In order to efficiently produce γ-valerolactone (GVL) from furfural , a Zr-graphitic carbon nitride/H-β composite (Zr CN/H-β) had been simply prepared via an impregnation-calcination protocol. The morphology and structure, elemental information, and total acid and base properties of the Zr CN/H-β and related catalysts (H-β, CN/H-β, and Zr/H-β) were determined by SEM, TEM , X-ray photoelectron spectroscopy (XPS), and temperature-programmed desorption (TPD-NH 3 , CO 2 ) characterizations. The effects of reaction temperature and time, and the furfural dosage on GVL production as well as the recyclability of Zr CN/H-β were investigated. With a catalyst/furfural dosage of 0.1/0.22 g, the Zr CN/H-β produced a remarkable 76.5% of GVL yield at 160 °C in 18 h using isopropanol as the solvent. The results of NH 3 , CO 2 -TPD experiments indicated that the simultaneous introduction of Zr species and carbon nitride onto H-β formed new types of acid and base, which should be responsible for the high efficient conversion of furfural to GVL. Additionally, the recyclability of Zr CN/H-β was reasonable.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2018
·Vol. 410
·期 28
·7373-7384
·
IF 3.307
Shi Yi,Peng Jun,Meng Xiaoyan,Huang Tao,Zhang Jingyi,He Hua
Here, one kind of hydrophilic hydroxypropyl β-cyclodextrin cross-linked polymer (HP-CDP) was prepared and used to establish a “turn-on” fluorescent probe for selective determination of captopril in biological samples. The HP-CDP has been synthesized in one step by cross-linking (2-hydroxypropyl)-β-cyclodextrin (HP-β-CD) with a rigid aromatic group linker tetrafluoroterephthalonitrile (TFT), and the synthesis parameters of HP-CDP were optimized with water solubility, yield, and adsorption capacity as indicators. When it was used as a luminescent material, we have found an interesting phenomenon that the fluorescence emission of HP-CDP was quenched after forming a coordination compound with ferric ions, and then recovered after adding a certain concentration of captopril, since captopril can reduce the ferric iron to ferrous ions and cause ligand replacement. Based on this observation, a novel turn-on fluorescent method was developed for the determination of captopril. The method exhibited good linearity in the range of 9.2 × 10 −7 to 4.6 × 10 −4 M ( R 2 = 0.9982) and a low detection limit of 1.8 × 10 −7 M at optimum HP-CDP concentration, ferric ion concentration, pH, and incubation time. Moreover, interference experiments demonstrated that this fluorescence sensor had excellent selectivity that can commendably resist the interference from potential foreign substances. The proposed method has been successfully applied to determine captopril in human urine samples and may provide outstanding application potential in the future development of sensors. In addition, it is believed that HP-CDP also has a wide range of applications, for example, as a solubilizer, pollutant adsorbent, or drug carrier.
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ELECTROCHIMICA ACTA
·
2018
·
IF 5.116
Xiaohui Niu,Xing Yang,Zunli Mo,Ruibin Guo,Nijuan Liu,Pan Zhao,Zhenyu Liu,Meixuan Ouyang
Two types of ferrocene-functionalized multiwalled carbon nanotubes (MWCNTs) are described. The first was obtained by adsorption of ferrocene (Fc) on MWCNTs via π-π stacking and is referred to as Fc/MWCNTs. The second was prepared via a conjugation reaction between ferrocenecarboxylic acid and aminated MWCNTs to result on covalently modified MWCNTs referred to as MWCNT-Fc. MWCNT/Fc has a better conductivity than MWCNT-Fc. But electrochemical recognition results clearly showed the MWCNTs-Fc/β-CD/GCE can exhibit better chiral recognition ability to tryptophan enantiomers than β-CD/Fc/MWCNTs/GCE. By combining the merits of β-cyclodextrin (β-CD) and MWCNTs-Fc, an electrochemical sensor for l -tryptophan was obtained. Its characterizations by SEM, TEM , TGA , Raman spectroscopy and XPS showed that the Fc/MWCNTs and MWCNTs-Fc have successfully been synthesized. Enantioselective recognition was accomplished by differential pulse voltammetry . Tryptophan enantiomers can be differentiated with an enantioselectivity coefficient (I D-Trp /I L-Trp ) of 5.78. Moreover, the chiral recognition mechanism of β-CD recognition tryptophan enantiomers was proposed.
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