JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2023
·Vol. 34
·期 26
·1-19
·
IF 2.8
Lu Zan,Yuan Li,Liang Guozheng,Gu Aijuan
An effective strategy is developed to improve the energy density for poly(vinylidene fluoride-hexafluoropropylene) (P(VDF-HFP)) composites through building novel multi-layered structure with gradient distribution of a low content of SiO 2 -coated potassium sodium niobate (KNN@SiO 2 ), and the resultant composites were coded as G-K@S/P. To discuss the mechanism behind the unique strategy, the P(VDF-HFP) composites with randomly distributed potassium sodium niobate (KNN) or gradient-distributed KNN, designed as K/P or G-K/P, were prepared; moreover, the structures and integrated properties of the three kinds of composites were systematically studied using experimental method and finite element simulations to declare the influence of both layered structure with gradient distribution and core–shell structure of fillers. Results show that compared to K/P and G-K/P composites, with the same total loading of fillers, G-K@S/P has a greater breakdown strength and energy density. When the filler content is as low as 1 wt%, the energy density of G-K@S/P is about 1.35 and 2.37 times of that of G-K/P and K/P, respectively, the improvement degrees are obviously higher than those of multi-layered polymer composites (SCI database), proving the effectiveness of the strategy. The mechanism behind is that combining the multi-layered structure with gradient distribution of a small content of KNN@SiO 2 plays a synergistic role to simultaneously improve the dielectric properties and breakdown strength and thus enhancing the energy storage performance of the composites.
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FISH PHYSIOLOGY AND BIOCHEMISTRY
·
2023
·
IF 2.9
Xu Xuhui,Zhou Mengyuan,Xie Kunmei,Zhang Shuai,Ji Xiaomeng,Sun Ying,Li Qiulu,Dong Zibo
Avermectin is widely used as an important insecticide in agricultural production, but it also shows strong toxicity to non-target organisms. Quercetin is a natural flavonoid that is widely used due to its good anti-inflammatory and antioxidant effects. We believe that quercetin may have a potential therapeutic effect on avermectin poisoning. This experiment was proposed to observe the effect of quercetin on the toxic response to avermectin by observing the toxic response caused by avermectin in the brain of carp. In this project, 60 carp were studied as control group (Control), quercetin administration group (QUE), avermectin exposure group (AVM) and quercetin treatment avermectin exposure group (QUE + AVM) with different interventions to study the effect of quercetin on avermectin. The carp brain tissues were stained and simultaneously analyzed for blood–brain barrier (BBB), oxidative stress indicators, inflammatory factors, and apoptosis using qPCR technique. The results of the study indicate that avermectin exhibits a neurotoxic mechanism of action in fish by decreasing the transcript levels of tight junction protein-related genes, which in turn leads to the rupture of the BBB in the carp brain tissue. Avermectin induced apoptosis in carp brain tissue by increasing oxidative stress response and promoting inflammatory cell infiltration. Quercetin could reduce the accumulation of reactive oxygen species (ROS) in the brain tissue of carp caused by avermectin exposure toxicity, maintain redox homeostasis, reduce inflammatory response, and protect brain tissue cells from apoptosis. The present study confirmed the therapeutic and protective effects of quercetin on neurotoxicity in carp caused by avermectin exposure.
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PubMed
高影响因子
FIBERS AND POLYMERS
·
2023
·Vol. 24
·期 12
·4279-4286
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IF 2.5
Zhou Jianhua,Niu Zhuanli,Xiao Anguo,Li Xiang
Materials with passive daytime radiative cooling (PDRC) have drawn more attention as a result of their potential for energy savings. We prepared SiO 2 -encapsulated ZnO@ZIF-8 (ZZS) particles and a radiative cooling coating containing ZZS particles. Owing to the polyhedron structure and the phonon-polarization resonance of ZZS particles, the ZZS fabric coating could reflect sunlight with 83% and radiate heat to outer space with 0.96. Compared with the ambient air, its average temperature decreased by 6.4 °C, and the human body under direct sunlight could avoid overheating 3.9 °C. In addition, the ZZS coated fabric after rubbing still had good PDRC and its average temperature increased by 1.38℃ higher than the original ZZS coated fabric. Owing to good PDRC property, hydrophobicity, mechanical properties and simple methods, the widespread usage of ZZS coated fabric for personal thermal management appears to be promising.
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JOURNAL OF MATERIALS SCIENCE
·
2023
·
IF 4.5
Liu Xinkai,Jing Kang,Peng Shaohua,Shi Qianru,Liu Hui
With acrylamide (AM), methacryloxyethyltrimethyl ammonium chloride, polyethyleneimine ethoxylated (PEI), and graphene oxide (GO) as the raw materials, an amino-functionalized GO-based recyclable composite aerogel (CPAM/PEI/GO, CPAM = cationic polyacrylamide) was constructed by a mild method. In order to verify successful preparation of the composite aerogel, it was characterized by Fourier infrared spectroscopy, Raman spectroscopy, scanning electron microscopy, and X-ray photoelectron spectroscopy. Since CPAM/PEI/GO had negative charge on the surface, methyl orange (MO), an anionic dye, was chosen as the adsorption molecule to study adsorption performance of the aerogel. The results showed that CPAM/PEI/GO possessed efficient adsorption performance toward MO, and the equilibrium adsorption capacity could attain 677.55 mg/g at 303 K. The adsorption process for CPAM/PEI/GO toward MO could be well simulated by pseudo-second-order kinetic and Langmuir adsorption model, and the adsorption was a spontaneous process. The main driving forces of adsorption process were hydrogen bonding, π – π conjugate interaction, and electrostatic interaction. Even after six adsorption–desorption cycles, the equilibrium adsorption capacity of CPAM/PEI/GO aerogel still could retain 536.99 mg/g, which indicated that the aerogel exhibited good regenerability. The composite aerogel might provide a new inspiration for the preparation of amino-functionalized GO-based aerogels and broaden their application field in wastewater treatment.
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JOURNAL OF SOLID STATE ELECTROCHEMISTRY
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2023
·
IF 2.5
Chen Lezi
Aqueous zinc ion batteries have shown great prospects in large-scale energy storage. However, severe dendritic growth and unrestrained side reactions have limited the high speed development of aqueous zinc ion batteries due to the instability of zinc anodes in aqueous electrolytes. Here, butanediol additive is introduced into ZnSO 4 electrolyte to improve the stability of zinc anode by adjusting the solvation structure of zinc hydration layer. This leads to a long cycle life (1000 h), which is more than 8 times greater than that of ZnSO 4 basic electrolyte, for Zn||Zn symmetric batteries utilizing 2 M ZnSO 4 and 15% butanediol additions. The butanediol additive can also achieve high Coulombic efficiency with an average value of 99.58% in Zn||Cu batteries. The Zn||V 2 O 5 full battery exhibits a maximum capacity of 205 mAh g −1 , and even after 1000 cycles at 1.0 A g −1 , it still has a high reversible specific capacity of 177 mAh g −1 .
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2023
·Vol. 415
·期 27
·6771-6783
·
IF 4.3
Ma Wanwan,Chen Huan,Hou Hongwei,Hu Qingyuan,Bai Yu
Phosphatidylcholine (PC) and lysophosphatidylcholine (LPC), two types of phospholipids (PLs), have been reported to be closely correlated with head and neck cancers of laryngeal cancer (LC) and thyroid cancer (TC), which make their analysis crucial. TiO 2 @COF-based solid-phase microextraction (SPME) coupled to UHPLC-MS/MS was developed for the rapid and accurate detection of seven potential PL biomarkers from small amounts of serum in this work. The combination of TiO 2 and COF proves to be effective for the extraction of the target analytes. Under optimal conditions, the developed TiO 2 @COF-based SPME-UHPLC-MS/MS method revealed good linearity ( R 2 ≥ 0.997) with LODs ranging from 0.05 to 0.38 ng/mL for PLs, the extraction recoveries and matrix effects ranging from 83.09–112.03% and 85.38–113.67%, respectively. As a high-throughput pretreatment method, satisfactory probe-to-probe reproducibility rates of 2.7–10.1% were obtained. Finally, the TiO 2 @COF-based SPME-UHPLC-MS/MS method was applied to analyze LPC 14:0, LPC 16:0, LPC 18:0, LPC 18:1, LPC 19:0, PC 16:0/18:1, and PC 18:0 in serum samples from early LC patients ( n = 15), early TC patients ( n = 15), and healthy volunteers ( n = 15). The results indicated that cancer patients could be effectively differentiated from healthy controls using orthogonal partial least squares discriminant analysis (OPLS-DA). In conclusion, the established TiO 2 @COF-based SPME-UHPLC-MS/MS method is reliable for the rapid determination of the seven PLs in serum samples, which is promising for early diagnosis of head and neck cancers. Graphical abstract
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PubMed
高影响因子
CELLULOSE
·
2023
·Vol. 30
·期 17
·11261-11272
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IF 5.7
Wang Junsheng,Zhuang Jie,Jin Wanhui,Yu Qian,Yu Jing,He Li,Wang Qiuhan,Cheng Deshan,Cai Guangming,Wang Xin
Textile-based wearable electronics have drawn increasing attention in recent years, but stable and durable conductive mechanism on textiles has been the challenge. In this study, we propose to fabricate a liquid metal circuit on textile substrates for flexible antennas and wearable sensors via screen printing method. The breakage of liquid metal circuit on cotton/lycra elastic fabrics can be repaired by pressing or heating, and the patterned liquid metal circuits can be removed using sodium hydroxide solution. Furthermore, the liquid metal circuit was designed as a pressure switch for thermal management system with the temperature precisely controllable by tuning the applied pressure. The liquid metal circuit was further designed as a flexible near field communication (NFC) antenna, providing identification capacity such as replacing campus card and protecting children. The maximum bending angle and effective distance of the NFC tag are determined to be 150 and 17.8 mm, respectively. In addition, the as-prepared liquid metal-based fabric sensors can accurately human motion detection in real time, exhibiting great potential in flexible wearable electronics.
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Nano Research
·
2023
·
IF 9.9
Qu Haijing,Chen Han,Cheng Wei,Pan Yuqing,Duan Zhiran,Wang Yanjun,Liang Xing-Jie,Xue Xiangdong
Although anti-cancer nanotherapeutics have made breakthroughs, many remain clinically unsatisfactory due to limited delivery efficiency and complicated biological barriers. Here, we prepared charge-reversible crosslinked nanoparticles (PDC NPs) by supramolecular self-assembly of pro-apoptotic peptides and photosensitizers, followed by crosslinking the self-assemblies with polyethylene glycol to impart tumor microenvironment responsiveness and charge-reversibility. The resultant PDC NPs have a high drug loading of 68.3%, substantially exceeding that of 10%–15% in conventional drug delivery systems. PDC NPs can overcome the delivery hurdles to significantly improve the tumor accumulation and endocytosis of payloads by surface charge reversal and responsive crosslinking strategy. Pro-apoptotic peptides target the mitochondrial membranes and block the respiratory effect to reduce local oxygen consumption, which extensively augments oxygen-dependent photodynamic therapy (PDT). The photosensitizers around mitochondria increased along with the peptides, allowing PDT to work with pro-apoptotic peptides synergistically to induce tumor cell death by mitochondria-dependent apoptotic pathways. Our strategy would provide a valuable reference for improving the delivery efficiency of hydrophilic peptides and developing mitochondrial-targeting cancer therapies.
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Tissue Engineering and Regenerative Medicine
·
2023
·
IF 3.6
Zhang Ying,Li Chuan,Wei Qiushi,Yuan Qiang,He Wei,Zhang Ning,Dong Yiping,Jing Zhenhao,Zhang Leilei,Wang Haibin,Cao Xiangyang
BACKGROUND: This study aimed to explore the effect of a nanomaterial-based miR-320a inhibitor sustained release system in trauma-induced osteonecrosis of the femoral head (TIONFH). METHODS: The miR-320a inhibitor-loaded polyethylene glycol (PEG)- Poly(lactic-co-glycolic acid) (PLGA)- Poly-L-lysine (PLL) nanoparticles were constructed using the double emulsion method. The TIONFH rabbit model was established to observe the effects of miR-320a inhibitor nanoparticles in vivo . Hematoxylin–eosin staining and microcomputed tomography scanning were used for bone morphology analysis. Bone marrow mesenchymal stem cells (BMSCs), derived from TIONFH rabbits, were used for in vitro experiments. Cell viability was determined using the MTT assay. RESULTS: High expression of miR-320a inhibited the osteogenic differentiation capacity of BMSCs in vitro by inhibiting the expression of the osteoblastic differentiation markers ALP and RUNX2. MiR-320a inhibitor-loaded PEG-PLGA-PLL nanoparticles were constructed with a mean loading efficiency of 1.414 ± 0.160%, and a mean encapsulation efficiency of 93.45 ± 1.24%, which released 50% of the loaded miR-320a inhibitor at day 12 and 80% on day 18. Then, inhibitor release entered the plateau. After treatment with the miR-320a inhibitor nanoparticle, the empty lacunae were decreased in the femoral head tissue of TIONFH rabbits, and the osteoblast surface/bone surface (Ob.S/BS), osteoblast number/bone perimeter (Ob.N/B.Pm), bone volume fraction, and bone mineral density increased. Additionally, the expression of osteogenic markers RUNX2 and ALP was significantly elevated in the TIONFH rabbit model. CONCLUSION: The miR-320a inhibitor-loaded PEG-PLGA-PLL nanoparticle sustained drug release system significantly contributed to bone regeneration in the TIONFH rabbit model, which might be a promising strategy for the treatment of TIONFH.
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高影响因子
TRIBOLOGY LETTERS
·
2023
·Vol. 71
·期 4
·1-13
·
IF 3.2
Fu Jingguo,Fan Liyang,He Yuhang,Yu Zhiwei,Ma Dengqing,Yin Huabing,Zhang Hongpeng
The combination of surface dimples and solid lubricant can improve the friction state between moving parts. However, the presence of surface dimples also leads to surface stress concentration, and the influence of these stresses on tribological properties is also worth studying. In this work, solid lubricant mixture polyimide and tungsten disulfide were firstly encapsulated in the dimples on the cylinder liner surface. The influence of surface stress concentration on the anti-friction performance of moving parts was then investigated through surface stress simulation and reciprocating friction and wear experiments. The results indicated that during reciprocating friction movement, surface stress concentration caused by the dimples mainly appeared at their edges. Moreover, as the diameter of the dimples increased, there was a gradual decrease in maximum surface stress on the cylinder liner. However, higher contact pressure and shear stress generated by edge-induced stress concentration could promote tribochemical reactions between Fe matrix and mixed solid lubricants polyimide and tungsten disulfide, resulting in formation of a solid lubrication film as well as iron–carbon and iron–nitrogen compounds that enhanced anti-friction effects.
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高影响因子
MEDICAL ONCOLOGY
·
2023
·Vol. 40
·期 11
·1-11
·
IF 3.4
Li Jun,Lin Chenyu,Zhu Yuqian,Shao Chengwei,Wang Tiegong,Chen Bingdi
The research of nanomaterials for bio-imaging and theranostic are very active nowadays with unprecedented advantages in nanomedicine. Homologous targeting and bio-imaging greatly improve the ability of targeted drug delivery and enhance active targeting and treatment ability of nanomedicine for the tumor. In this work, lycorine hydrochloride (LH) and magnetic iron oxide nanoparticles coated with a colorectal cancer (CRC) cell membrane (LH-Fe 3 O 4 @M) were prepared, for homologous targeting, magnetic resonance imaging (MRI), and chemotherapy. Results showed that the LH-Fe 3 O 4 @M and Fe 3 O 4 @M intensity at HT29 tumor was significantly higher than that Fe 3 O 4 @PEG, proving the superior selectivity of cancer cell membrane-camouflaged nanomedicine for homologous tumors and the MRI effect of darkening contrast enhancement were remarkable at HT29 tumor. The LH-Fe 3 O 4 @M exhibited excellent chemotherapy effect in CRC models as well as LH alone and achieved a high tumor ablation rate but no damage to normal tissues and cells. Therefore, our biomimetic system achieved a homologous targeting, bio-imaging, and efficient therapeutic effect of CRC.
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高影响因子
Nano Research
·
2023
·
IF 9.9
Chen Yan,Yang Zhenrui,Wang Juan,Yang Yun,He Xuedong,Wang Yang,Chen Jiadong,Guo Yaqing,Wang Xin,Wang Shun,Jin Huile
Enhancing catalytic activity through modulating the interaction between N-doped carbon and metal phosphides clusters is an effective approach. Herein, the electronic structure modulation of CoP 2 supported N-modified carbon (CoP 2 /NC) has been designed and prepared as efficient electrocatalysts for oxygen reduction reaction (ORR), oxygen evolution reaction (OER), and hydrogen evolution reaction (HER). Notably, CoP 2 /NC-1 catalyst exhibits impressive performance in alkaline media, with an ORR half-wave potential of 0.84 V, as well as OER and HER overpotentials of 290 and 129 mV (at 10 mA·cm −2 ), respectively. In addition, CoP 2 /NC-1 produces a power density as high as 172.9 mW·cm −2 , and excellent reversibility of 100 h at 20 mA·cm −2 in home-made Zn-air batteries. The experimental results demonstrate that the synergistic interactions between N modified carbon substrate and CoP 2 material significantly enhance the kinetics of ORR, OER, and HER. Density functional theory (DFT) calculations reveal the strong electrons redistribution of CoP 2 induced by high-density N atoms at the interface, thus optimizing the key intermediates and significantly lower the energy barrier of reactions. These electronic adjustments of CoP 2 greatly enhance its kinetics of ORR/OER/HER, leading to faster reactions. This study provides profound insights into the specific modification of CoP 2 by N-doped carbon, enabling the construction of efficient catalysts.
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