Acta Biomaterialia
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2022
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IF 10.633
Shipeng Ning,Xingliang Dai,Weiwei Tang,Qinglong Guo,Meng Lyu,Daoming Zhu,Wei Zhang,Haisheng Qian,Xiaxi Yao,Xianwen Wang
Sonodynamic therapy (SDT) is a promising strategy for tumor treatment that satisfies all requirements of penetrating deep-seated tissues without causing additional trauma. However, the hypoxic tumor microenvironment impairs the therapeutic effect of SDT. The synergistic treatment of oxygen concentration-dependent SDT and bio-reductive therapy has been proven to be an effective approach to improve the therapeutic efficiency of SDT by exploiting tumor hypoxia . Herein, a biomimetic drug delivery system (C-TiO 2 / [email protected] ) was successfully synthesized for combined SDT and hypoxia-activated chemotherapy, which was composed of tirapazamine (TPZ)-loaded C-TiO 2 hollow nanoshells (HNSs) as the inner cores and cancer cell membrane (CM) as the outer shells. C-TiO 2 HNSs coated with CM achieved tumor targeting via homologous binding. C-TiO 2 @CM as a nanocarrier loaded with TPZ in the presence of the trapping ability of CM and the special cavity structure of C-TiO 2 HNSs. Moreover, C-TiO 2 HNSs as sonosensitizers killed cancer cells under ultrasound (US) irradiation. Oxygen depletion during SDT induced a hypoxic environment in the tumor to activate the killing effect of co-delivered TPZ, thereby obtaining satisfactory synergistic therapeutic effects. In addition, C-TiO 2 @CM exhibited remarkable biocompatibility without manifest damage and toxicity to the blood and major organs of the mice. The study highlighted that C-TiO 2 / [email protected] served as a powerful biomimetic drug delivery system for effective SDT by exploiting tumor hypoxia. Statement of significance • C-TiO 2 @CM achieved tumor targeting via homologous binding. • C-TiO 2 hollow nanoshells could be used as a sonosensitizer and drug carrier for synergistic SDT and hypoxia-activated chemotherapy. • C-TiO 2 / [email protected] showed no obvious toxicity under the injection dose.
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INORGANIC CHEMISTRY COMMUNICATIONS
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2022
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IF 3.428
Jianyin Zhang,Xiuxia Lu,Xiaoxiao Shi,Haohao Liu,Limin Zhang,Xingwei Shi
Using (BiO) 2 CO 3 as the raw material and a simple molten salt process followed by ball-milling, mass manufacturing of 2D layered BiOCl nanoplates and carbon composites can be produced. XRD, XPS, SEM, and TEM were used to characterize the as-synthesised materials in great detail. Eletrochemical experiments demonstrate that after 100 cycles at a current density of 100 mA g −1 , the discharge capacity of the BiOCl@C composite electrode remains at 410 mAh/g, and average coulombic efficiencies can remain as high as 99 % after the first cycle. This work would establish a novel method for producing high-volumetric-energy–density BiOCl@C anode materials, which are likely to be viable candidates for application in lithium-ion batteries.
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CHEMICAL ENGINEERING JOURNAL
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2022
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IF 16.744
Xiangjie Chen,Qingquan Kong,Xiaoqiang Wu,Xuguang An,Jing Zhang,Qingyuan Wang,Weitang Yao
Aqueous zinc-ions batteries (AZIBs) are expected to be a new green energy storage devices due to the low cost and safety. As classic cathode materials for AZIBs, layered vanadium oxides have excellent redox activity and large capacity performance. However, it not only has poor conductivity, but easily dissolved during (dis)charge process. Therefore, it is necessary to modify vanadium oxide to improve electrochemical performance in AZIBs. Herein, we successfully synthesized V 2 O 3 with carbon shell (V 2 O 3 @C) by the reduction reaction of carbon with V 2 O 5 in an oxygen-free environment and tested its electrochemical performance. By exploiting the effect of different calcination temperatures on the carbon reduction reaction, V 2 O 3 @C nanospheres with different carbon shell thicknesses were successfully synthesized. After fitting the experimental data, the calcination temperature for optimal electrochemical performance was determined to be 800 ℃ (VC-800). Detailly, the capacities of V 2 O 3 @C obtained at 700, 800 and 900 ℃ in the first 100 cycles at 0.5 A/g were 454.5, 400.7 and 325.1 mAh/g, respectively. Furthermore, the obtained VC-800 showed 126 % capacity retention after 10,000 cycles at 10 A/g. In the presence of carbon shell, V 2 O 3 maintains the reversible redox valence characteristics while improving the conductivity and cycle life. This work may broaden ideas in improvement of vanadium-based materials for zinc ion storage.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2022
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IF 6.371
Guiyang Xian,Ximing Zhang,Zhaolin Zhu,Yan Wang,Chongmei Wu,Yin Liu,Zhenying Liu,Xianglong Wan,Konghu Tian,Lingbing Kong
The excellent electromagnetic wave (EMW) absorption performance of metal organic frameworks (MOFs) has attracted a lot of attention. In this work, zeolitic imidazolate framework-67 (ZIF-67) was synthesized hydrothermally using 2-methylimidazole (2-mIm) as the organic ligand, cobalt nitrate hexahydrate (Co(NO 3 ) 2 ·6H 2 O) as the cobalt source and methanol (MeOH) as the organic solvent . The ZIF-67 was etched with cerium nitrate hexahydrate (Ce(NO 3 ) 3 ·6H 2 O), leading to rhombic dodecahedron Ce–Co/C composites with porous hollow structure after thermal annealing. In addition, the effect of the content of Ce(NO 3 ) 3 ·6H 2 O on EMW absorption performance of the Ce–Co/C composites was studied. Specifically, the sample Ce–Co/C-2 (Ce(NO 3 ) 3 ·6H 2 O): (ZIF-67 = 1:2) showed optimal EMW performance. For the Ce–Co/C-2 based composite with a filling ratio of 45 wt%, a RL min reached −64.67 dB at 11.12 GHz with a thickness of 2.21 mm. The promising EMW absorption performance of the porous hollow structure was attributed to its large specific surface area and massive defects, multiple reflection/scattering, improved impedance matching and increased dielectric loss. This work provides a reference improve EMW absorption performance of MOF materials through regulating their microstructures.
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Materials
·
2022
·Vol. 15
·期 12
·4242
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IF 3.748
Xishi Wu,Qing Huang,Yunzhou Zhu,Zhengren Huang
In this study, the joining of silicon carbide (SiC) ceramics was achieved via a Si–C reaction bonding method using the phenolic resin (PF)–MgCl2system as the carbon precursor. Specifically, by adding MgCl2to the phenolic resin mixture, the average pore size of the product of carbonization of the PF resin mixture increased from 14 ± 5 nm to 524 ± 21 nm, which was beneficial for the infiltration of molten silicon at high temperature. The microstructure of the joined specimens and the effect of the inert filler on the joint strength were investigated. It was demonstrated that SiC–SiC joints with strong interfacial bonding and high flexural strength could be obtained by the Si–C reaction bonding method using a phenol formaldehyde resin/alcohol sol-gel system as the carbon precursor. The flexural strength of the joined specimens reached the highest value, i.e., 308 ± 27 MPa when the solid loading of the inert filler was 26%. Overall, stable joining of silicon carbide ceramics was achieved by the proposed method, which has significance for realizing the preparation of complex-shaped or large silicon carbide ceramic parts.Keywords:SiC ceramic;joining technology;MgCl2;phenolic resin/alcohol carbon precursor;grains and interfaces
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Redox Biology
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2022
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IF 10.787
Han Xie,Li Song,Sagie Katz,Jinyu Zhu,Yawen Liu,Jinping Tang,Linjun Cai,Peter Hildebrandt,Xiao Xia Han
Generation of reactive oxygen species (ROS) are possibly induced by the crosstalk between mitochondria and endoplasmic reticula, which is physiologically important in apoptosis. Cytochrome c (Cyt c ) is believed to play a crucial role in such signaling pathway by interrupting the coupling within microsomal monooxygenase (MMO). In this study, the correlation of ROS production with the electron transfer between Cyt c and the MMO system is investigated by resonance Raman (RR) spectroscopy. Binding of Cyt c to MMO is found to induce the production of ROS, which is quantitatively determined by the in-situ RR spectroscopy reflecting the interactions of Cyt c with generated ROS. The amount of ROS that is produced from isolated endoplasmic reticulum depends on the redox state of the Cyt c , indicating the important role of oxidized Cyt c in accelerating apoptosis. The role of electron transfer from MMO to Cyt c in the apoptotic mitochondria-endoplasmic reticulum pathway is accordingly proposed. This study is of significance for a deeper understanding of how Cyt c regulates apoptotic pathways through the endoplasmic reticulum, and thus may provide a rational basis for the design of antitumor drugs for cancer therapy.
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高影响因子
RSC Advances
·
2022
·Vol. 12
·期 27
·17012-17019
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IF 4.036
Yubing Xue,Dashu Pan,Feng Zuo,Songtao Xiao,Xiang Li,Fuyan Lou,Mingming Li,Yinggen Ouyang
A novel self-reactivated catalyst Pt–ThO2/C was prepared for the first time by selecting radioactive material ThO2 as the catalytic additive to address the low activity and toxicity of the anode Pt/C catalyst in a direct ethanol fuel cell. The catalytic activity and resistance to CO poisoning of Pt-6.67 wt%ThO2/C were found to be superior to those of Pt/C–NaBH4 in electrochemical workstation and single-cell tests. It is speculated that the exist of ThO2 not only improves the catalytic activity via the synergistic effect of Pt and Th, but also produces a large amount of radiolysis products, OH radicals, due to 232Th which oxidatively desorbs CO from Pt–COads and solves the CO poisoning problem.
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Chemistry-An Asian Journal
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2022
·Vol. 17
·期 20
·e202200793
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IF 4.839
Wei Sun,Xiaofang Chen,Yi Li,Wei Liu,Hongkun Li,Yonggang Yang
Graphical Structurally coloured organic-inorganic hybrid silica films with a SmC* structure were prepared. Due to the light scattering of the nanoparticles on film surface and the selective Bragg reflection of film inside, the colourful patterns can be observed in the oblique view and not be observed in the vertical view. Therefore, the OIHS films can be used for anti-counterfeiting. Artificial photonic materials based on chiral liquid-crystalline nanostructures have attracted increasing interests for their wide applications as sensors, anti-counterfeit measures, displays and colour filters. Although the structurally coloured films with chiral nematic structures or blue phases have been prepared, the ones fabricated by fixing chiral smectic C (SmC*) phases have been rarely reported. In this work, organic-inorganic hybrid silica (OIHS) films with a SmC* structure were reported for the first time. An organosilane (CSC) with an enantiotropic SmC* phase was synthesized. The OIHS films with a SmC* structure were fabricated by the polycondensation of CSC under an acidic condition. The colour patterns can be observed in the oblique view, but not be observed in the vertical view, which is mainly due to the light scattering of the nanoparticles on film surface and the selective Bragg reflection of film inside. Therefore, such properties make the OIHS films promising candidates for anti-counterfeiting applications.
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APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Liu Cui,Ziwei Bai,Ziqi Li,Zhaoyun Liu,Huanhuan Ma,Xiaoxu Chen,Kui Lin,Jia Hao,Yuanlu Cui,Fei Tian
Photocatalytic process using core–shell nano-catalyst is an efficient, eco-friendly, and cost-effective process for removal or minimize hazard of pollutants in waste water. Herein, a recyclable and robust Cu 2 O/Fe 3 O 4 @C/Cu core–shell nanocomposite with photocatalyst activities is designed based on the synergistic photocatalytic activities of Cu 2 O and Cu and the magnetic property and stability of Fe 3 O 4 @C. The Cu 2 O/Fe 3 O 4 @C/Cu is shown to act as nano-catalyst to almost completely convert 4-Nitrophenol (4-NP) to 4-aminophenol (4-AP) within 3 min by sufficient electrons in the electron-rich region formed under ultraviolet light irradiation. The Cu 2 O/Fe 3 O 4 @C/Cu nanocomposite shows a good stability, reusability and magnetic separation ability after five recycles. In addition, a photocatalytic mechanism of 4-NP reduction over this nanocomposite is proposed, and the roles of each nanocomponent of this nanostructure played in the synergistic enhancing photocatalytic performance via cascade reaction is demonstrated. This work suggests that Cu 2 O/Fe 3 O 4 @C/Cu nanocomposite with high activity, good stability and magnetically recyclability could be applied for the elimination of pollutants in wastewater.
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Gels
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2022
·Vol. 8
·期 10
·600
·
IF 4.432
Peng Liu,Caili Dai,Mingwei Gao,Xiangyu Wang,Shichun Liu,Xiao Jin,Teng Li,Mingwei Zhao
In order to broaden the application of clean fracturing fluid in ultra-high temperature reservoirs, a surfactant gel for high-temperature-resistant clean fracturing fluid was developed with a gemini cationic surfactant as the main agent in this work. As the fracturing fluid, the rheological property, temperature resistance, gel-breaking property, filtration property, shear recovery performance and core damage property of surfactant gel were systematically studied and evaluated. Results showed the viscosity of the system remained at 25.2 mPa·s for 60 min under a shear rate of 170 s−1at 200 °C. The observed core permeability damage rate was only 6.23%, indicating low formation damage after fracturing. Due to micelle self-assembly properties in surfactant gel, the fluid has remarkable shear self-repairability. The filtration and core damage experimental results meet the national industry standard for fracturing fluids. The gel system had simple formulation and excellent properties, which was expected to enrich the application of clean fracturing fluid in ultra-high temperature reservoirs.Keywords:clean fracturing fluid;VES;surfactant gel;rheology behavior;thermal stability
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PHYTOCHEMISTRY
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2022
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IF 4.004
Sheng-Qi Zhang,Jia-Peng Wang,Feng-Mei Zhang,Lin-Lin Yao,Bing-Xian Li,Ya-Ni Li,Dong Gan,Rui-Feng Mei,Le Cai,Zhong-Tao Ding
A chemical investigation of the endophytic fungus Diaporthe destruens from the Hernandiaceae plant Illigera orbiculata C. Y. Wu collected from southern Yunnan Province, China, led to the isolation of six undescribed compounds, including two azaphilone analogs, which are a pair of epimers (13 R- hydroxy-chermesinone A and 13 S- hydroxy-chermesinone A); a pyrrole derivative (1-(4-(methoxymethyl)-1H-pyrrol-3-yl)ethan-1-one); an isoindolone derivative (4-hydroxy-6-methoxyisoindolin-1-one); a benzylbenzene derivative (destruensine A) and a conjectural fragment of polyketide ((2 R ,4 R )-2-(methoxymethyl)pentane-1,4-diol) along with nine known compounds. Their structures were elucidated by spectroscopic methods and HRESIMS, and the absolute configurations were further confirmed by electronic circular dichroism (ECD) and chemical derivatization . The antimicrobial activities , anti-acetylcholinesterase activities, antiproliferation, and NO production inhibitory effects of compounds 1 – 15 were evaluated.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2022
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IF 7.139
Qiongqiong Wang,Yaxi Tian,Mengyun Chen,Rongfeng Guan,Haibin Yuan
Photocatalytic production H 2 of splitting water is an important branch of the application of photocatalytic materials. In this paper, porous C doped carbon nitride was successfully synthesized by calcining urea and acetamide at high temperature, and then analyzed by various characterization methods. XRD and FT-IR spectra show that the crystal structure of carbon nitride modified by acetamide are similar to bulk carbon nitride. SEM and TEM spectra show that the morphology and structure of carbon nitride and carbon nitride was modified by acetamide, which presents a porous nanosheets structure. XPS and EDS show that the content of carbon element in carbon nitride modified by acetamide increased significantly. The PL spectrum is obviously red shift, and the light absorption range is obviously enlarged, which is consistent with the absorption edge of UV–vis Spectrum. The BET of the optimized sample CN2-6 is 122.79 m 2 g -1 , which is 3.04 times higher than that of bulk carbon nitride CN1 (40.456 m 2 g -1 ). In addition, the hydrogen production of CN2-6 is 13169.04 μmol/g/h under 300 W Xenon lamp, which is 14.95 times more than CN1 (880.82 μmol/g/h) hydrogen production rate. When the light source is a 10 W LED lamp , the apparent quantum efficiency (AQE) of sample CN2-6 reaches the maximum (2.91) under the wavelengths of 430 nm, which is 1.27 times more than CN1 under the same conditions. Meanwhile, prepared samples have excellent stability and durability under visible light.
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