CRYSTENGCOMM
·
2021
·Vol. 24
·期 1
·77-82
·
IF 3.545
Dandan Wang,Xiaoqing Jiang,Pifu Gong,Xinyuan Zhang,Zheshuai Lin,Zhanggui Hu,Yicheng Wu
An alkali metal gallium iodate, Cs3[Ga2O(I3O9)(IO3)4(HIO3)] (CGIO), was synthesized by the traditional hydrothermal method. Interestingly, CGIO revealed a novel I3O93− fundamental building block (FBB) constituted by two IO3 tetrahedrons and one IO5 polyhedron through sharing O atoms. The new I3O93− trimer forms a 0D [Ga2O(I3O9)(IO3)4(HIO3)]3− anion cluster together with the [Ga2O11]16− dimer and isolated IO3− units. The UV-vis-NIR diffuse reflectance spectrum of CGIO shows a wide bandgap of 4.05 eV, and the thermal stability could reach above 400 °C. First-principles calculations explicated that the optical properties of CGIO mainly originated from the iodate anion units with a calculated birefringence of 0.04 at 1064 nm.
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NEW JOURNAL OF CHEMISTRY
·
2019
·Vol. 43
·期 11
·4640-4647
·
IF 3.069
Wei-Song Gao,Jin-Miao Wang,Ning-Ning Shi,Chang-Neng Chen,Yu-Hua Fan,Mei Wang
To mimic the strategy used by natural photosynthesis in Photosystem II, which adopts the cubic Mn4CaO5 cluster as a natural oxygen-evolving complex, a bio-inspired cubane-like tetranuclear cluster [Cu4(pdmH)4(OAc)2](NO3)2·3H2O (1) has been synthesized successfully with pyridine-2, 6-dimethanol as the ideal ligand, and investigated by X-ray crystallography, PXRD, in situ UV-vis-NIR spectroelectrochemical analysis, and magneto- and electrochemistry. By X-ray analysis, it is shown that the distorted cubane-like core Cu4(μ3-O)4 is composed of four CuII and four μ3-O which arrange at the vertices of a slightly distorted cube. Electrochemical studies indicate that complex 1 presents potential properties as an effective molecular catalyst for electrocatalytic water oxidation under aqueous alkaline conditions at a potential of ∼1.20 V vs. NHE with a relatively low overpotential of ∼400–665 mV vs. NHE, which may result from the unique covalent metal–oxo bonding. Magnetic susceptibility measurements reveal that complex 1 displays overall antiferromagnetic exchanges between the Cu(II) ions within the clusters. Temperature dependence of in-phase (χM′) ac susceptibility signals display frequency-dependence, whereas the out-of-phase (χM′′) signals show no significant frequency-dependence for complex 1, which indicates that the complex may not be a SMM.
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DALTON TRANSACTIONS
·
2022
·Vol. 51
·期 31
·11703-11712
·
IF 4.569
Jun Sun,Minghui Zhou,Bei Zhang,Youjie Hua,Feifei Huang,Hongping Ma,Renguang Ye,Shiqing Xu
A series of Rb1−yKyNa3(Li3SiO4)4:Eu2+(0 ≤ y ≤ 1) phosphors were successfully synthesized through a high-temperature solid-state reaction. The introduction of K+ into the RbNa3(Li3SiO4)4:Eu2+ phosphor to partially or completely replace Rb+ allows the emission spectrum to be modulated from blue (λ = 473 nm, FWHM = 22.5 nm) to a narrow cyan band (λ = 485 nm, FWHM = 21.1 nm). As the K+ ion content increases, the space group of the phosphor evolves from I4/M to I41/A. The complete replacement of Rb+ by K+ results in the KNa3(Li3SiO4)4:Eu2+ cyan phosphor, which shows excellent thermal stability (the comprehensive emission loss is only 8% at 150 °C) and can be used to fill the cyan light gap in white LED devices. By adding the KNa3(Li3SiO4)4:Eu2+ cyan phosphor in packaging with yellow and red phosphors, the color rendering index is increased from 90.2 to 97.1 and the correlated color temperature improved to 3658 K. These results indicate that the cyan phosphor has important application value in full-spectrum white LEDs.
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SOLID STATE IONICS
·
2019
·
IF 2.886
Guangping Chen,Chaoqun Niu,Yubing Chen,Wenyan Shang,Yanyu Qu,Zhi Du,Lingzhu Zhao,Xiaoxue Liao,Jie Du,Yong Chen
Lithium metal anode is regarded as promising potential electrode for next-generation secondary batteries. However, the security issues caused by the growth of lithium dendrites hinder the development of lithium metal batteries . In this study, we prepare a single-ion conducting polymer electrolyte with semi-interpenetrating polymer network based on poly(lithium 4-styrenesulfonate). By eliminating the large electric fields near the lithium anode, the growth of lithium dendrite is suppressed effectively according to space-charge theory. The structurally optimized poly(lithium 4-styrenesulfonate)@polymethylmethacrylate single-ion conducting polymer electrolyte containing 2 wt% ethylene glycol dimethacrylate exhibits extremely high lithium ion transference number (0.91), promising ionic conductivity (0.97 × 10 −3 S cm −1 at 25 °C) along with wide electrochemical window of 4.7 V (vs. Li + /Li). Furthermore, the LiFePO 4 /membrane/Li cell achieves stable cycling performance (capability retention rate of 93.8% after 78 cycles at 1 C (1 C = 170 mAh g −1 ) and high coulombic efficiency 99.4%) along with superior discharge rate capability at room temperature . These excellent performances show that the single-ion conducting polymer electrolyte is a potential candidate for safe lithium metal batteries .
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JOURNAL OF MOLECULAR STRUCTURE
·
2025
·
IF 4.7
Dantong Wang,Hanqing Xie,Yongqi Zeng,Fengxi Li,Lei Wang,Peng Chen,Zhi Wang
This study presented, for the first time, a method for synthesizing 4-amino-3,5-dicyano-6-aryl phthalates using porcine pancreatic lipase (PPL) as a catalyst. We synthesized 18 derivatives of 4-amino-3,5-dicyano-6-aryl phthalates employing aryl aldehyde, acetylenic esters, and malononitrile under optimal conditions for 4 h, with water serving as the primary reaction medium. The yields of the target products ranged from moderate to high, achieving 43 % to 95 %. This method demonstrates an excellent tolerance for various functional groups. Furthermore, this paper elucidates the reaction mechanism through molecular docking studies and confirms the interaction between the substrate and lipase. The data indicate that the measured distance from the substrate to the catalytic triad is 3.8 Å, with a binding energy of -4.6 kJ/mol, suggesting that PPL demonstrates the strongest catalytic potential in this specific reaction. Additionally, the aforementioned products underwent molecular docking analysis with three selected enzyme targets from Leishmania, highlighting their potential as lead compounds for anti-Leishmania activity.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Hanhan Zhao,Wenjun Jiang,Yinhua Ma,Liubin Pei,Jiayu An,Su Zhan,Feng Zhou
The inherent electron-hole recombination, low light-absorption capacity and poor selectivity of photocatalysts hinder the production efficiency of hydrogen peroxide (H 2 O 2 ), necessitating the development of a catalyst with high catalytic activity. In this study, a supramolecular self-assembly method was employed to prepare 4-aminobenzonitrile-modified carbon nitride (Abz-CN). The incorporation of the cyano group rendered the charge distribution of Abz-CN inhomogeneous, leading to an increased dipole moment. This enhancement facilitated the separation and migration of photoinduced carriers. Additionally, density functional theory (DFT) calculations revealed that Abz-CN had a higher propensity for oxygen adsorption and the formation of *OOH intermediates compared to carbon nitride (BCN). The H 2 O 2 generation rate of Abz-CN reached 3866 μmol·g −1 ·h −1 (under a 180 W xenon lamp, λ > 400 nm), which was 5.2 times that of BCN. Furthermore, the mechanism of Abz-CN followed a sequential two-step single-electron oxygen reduction process. This study showcases an innovative approach for bolstering the efficiency of photocatalytic H 2 O 2 generation.
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Advanced Science
·
2025
·
IF 14.1
Renjie Cao,Tingting Zhao,Ying Wang,Shaofei Song,Yuan Li,Mengling Hou,Yanxin Zhang,Sengpeng Wong,Siqi Wang,Yuran Wang,Hong Peng,Min Huang,Yiming Jiang
Macrophage proinflammatory hyperactivation drives the pathogenesis of acute liver injury, a common complication of sepsis. The role of the nuclear receptor constitutive androstane receptor (CAR) in endotoxin-induced liver injury remains unclear. Here, this study reports that CAR is highly expressed in human and murine macrophages. CAR activation markedly attenuated endotoxin-induced liver damage, alleviating hepatocyte death and hepatic inflammation. Macrophage-hepatocyte coculture confirmed that CAR inhibited inflammation through macrophage crosstalk. CAR-mediated hepatoprotection and anti-inflammatory effects are absent in AAV8- F4/80- sh Car -treated mice, confirming the essential role of CAR in macrophages. Mechanistically, CAR is found to interact with Tlr4 , and the suppressive effects of CAR on TLR4 are proven in Tlr4 −/− mice. Furthermore, CAR activation reduced LPS-induced inflammation in hMDMs, BMDMs, RAW264.7, and THP-1 cells, and Car or Tlr4 knockdown abolished CAR-mediated immunosuppression. Overall, these findings showed that macrophage CAR activation attenuated endotoxin-induced liver injury and hepatic inflammation through the TLR4 signaling pathway, providing insights for treating inflammatory liver diseases.
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DOI
PubMed
高影响因子
MOLECULES
·
2025
·Vol. 30
·期 16
·3400
·
IF 4.6
Lina Hu,Mengjiao Li,Zheng Liu,Hui Yan,Xuekun Wang,Shiben Wang
To discover novel, potent anticonvulsant compounds, a series of compounds containing triazole structural fragments were synthesized and evaluated for their anticonvulsant activity. Compounds6f(maximal electroshock (MES), 50% effective dose (ED50) = 13.1 mg/kg; subcutaneous pentylenetetrazole (scPTZ), ED50= 19.7 mg/kg) and6l(MES, ED50= 9.1 mg/kg;scPTZ, ED50= 19.0 mg/kg) showed the best activity in MES andscPTZ tests. The results of an affinity test showed that the potent compounds had better binding to the GABAAreceptors. The results of an inhibitory neurotransmitter GABA content test in brain tissue indicated that compounds6fand6lexerted anticonvulsant activity which may be associated with the increase of GABA content in the rat brain. Elevated plus maze (EPM) assay results showed that compounds6fand6lpossessed anxiolytic effects, and their effects correlated with the binding sites of benzodiazepines (BZs) in the GABAAreceptors. Molecular docking was performed to investigate the interactions of the studied compound6lwith the GABAAreceptors on the molecular level.
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PubMed
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Desalination and Water Treatment
·
2024
·
IF 1
Youning Chen,Min Wang,Shuang Jia,Yuhong Li,Xiaohua Meng,Xiaoling Yang
ABSTRACT A novel poly(4-styrene sulfonic acid)-graft resin (PSS-g-PS) with high adsorption capacity was prepared by grafting poly(4-styrene sulfonic acid) (PSS) onto chloromethylated styrene resin via surface-initiated atom transfer radical polymerization. The surface composition of the poly(4-styrene sulfonic acid)-grafted resin were characterized by Fourier-transform infrared spectrometry, scanning electron microscopy, energy-dispersive X-ray spectroscopy and X-ray photoelectron spectroscopy. It was found that the grafting amount of 4-styrenesulfonic acid increased linearly with the polymerization time. Effect of parameters such as pH, initial concentration and temperature on the removal of heavy metal ions was studied. The maximum adsorption capacities of the resin were up to 275 mg·g –1 for Pb(II), 169 mg·g –1 for Cu(II), 115 mg·g –1 for Cd(II), 90.8 mg·g –1 for Cr(III) and 75 mg·g –1 for Ni(II) at pH 5.0. The adsorption isotherms of the five metal ions were best described by the Langmuir model, and their adsorption kinetics followed the pseudo-second-order kinetic equation. Thermodynamic studies showed that the adsorption was spontaneous. Furthermore, the resins still maintained good adsorption capacity after 10 cycles of adsorption–regeneration. All the results suggested that the resin could be potentially applied to the efficient removal of heavy metal ions from wastewater.
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ChemistrySelect
·
2025
·Vol. 10
·期 15
·e202406023
·
IF 2
Leyao Chen,Nuoya Wang,Xiaoyu Chang,Ruiyong Wang
Graphical This work investigated the inhibition of 4-thiazolidinone derivatives on SARS-CoV-2 Mpro using enzyme assays, spectroscopy, and molecular docking. Compound 3a showed the best inhibition (IC 50 = 2.36 ± 0.36 µM, K i = 1.72 µM), and the trifluoromethyl group in 3a played an important role. Hydrogen bonding and van der Waals forces were the main forces for the binding. This work provided clues for Mpro inhibitor development. Since the outbreak of COVID-19, one of the strategies used to search for potential drugs has been to screen inhibitors of SARS-CoV-2 Mpro. This work investigated the inhibitory effects of 4-thiazolidinone derivatives on main protease (Mpro) using various methods, including enzyme activity assays, enzyme kinetics, spectroscopy experiments, molecular docking simulations, microscale thermophoresis, and cytotoxicity tests. Compound 3a demonstrated the best inhibition effect among the compounds tested, with IC 50 = 2.36 ± 0.36 µM and K i = 1.72 µM. The trifluoromethyl group in 3a might enhance its inhibition ability. Interactions between the 4-thiazolidinone derivatives and Mpro resulted in fluorescence quenching primarily through static quenching. Thermodynamic analysis indicated that the interaction forces are mainly hydrogen bonds and van der Waals forces. Spectral results revealed that the 4-thiazolidinone derivatives affected the microenvironment of aromatic amino acid residues in Mpro and altered its secondary structure. Differential scanning fluorimetry was used to confirm the interaction between the 4-thiazolidinone derivatives and Mpro. Results of microscale thermophoresis indicated that the K d between 3a and Mpro was 1.56 ± 0.24 µM. Molecular docking simulations provided a more intuitive visualization of the interaction forces. This study provides clues for screening novel Mpro inhibitors.
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CHEMISTRY-A EUROPEAN JOURNAL
·
2025
·
IF 3.7
Zhicheng Tang,Tianwei Wang,Hua Lin,Shoulong Hao,Shufen Zhang,Rongwen Lu
Amination of 1-amino-4-bromoanthraquinone-2-sulfonic acid (BAA), crucial for anthraquinone-type dyes production, relies on Cu+ catalysis. However, Cu+ disproportionation causes catalyst deactivation, requiring large amounts of Cu catalysts (e.g., CuSO4 or CuCl) and reductants (e.g., FeSO4), introducing heavy metals and increasing water consumption to remove byproducts and metals, raising both environmental and economic costs. To address these challenges, we introduce a groundbreaking strategy for the in-situ generation of Cu+ using symmetrical Cu electrodes under alternating current (AC) electrolysis. This method achieves 100% conversion of BAA in the amination with 3,5-diamino-2,4,6-trimethylbenzene sulfonic acid (M Acid) with 95% yield, while also providing a solution to the issue of Cu+ disproportionation without the need for any additional copper catalysts or reductants, demonstrating a broad substrate scope and significantly reducing water usage in post-treatment. Characterization techniques, including X-ray photoelectron spectroscopy, X-ray diffraction, and electrochemical impedance spectroscopy, reveal that the passive Cu2O film formed on the symmetrical Cu electrodes under AC electrolysis continuously generates Cu+, which is crucial for the reaction. This approach is scalable, environmentally friendly, and holds great potential for industrial applications, offering substantial economic benefits while reducing environmental impact.
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DOI
PubMed
高影响因子
Separations
·
2024
·Vol. 11
·期 11
·305
·
IF 2.5
Jingmin Duan,Yafei Zhao,Zhuhe Zhai,Shengqiang Chen,Bing Zhang
Efficient and low-cost nanocatalysts are extremely desirable for the catalytic reduction of 4-nitrophenol (4-NP). A smaller nanocatalyst particle size and stronger support effect can significantly enhance the catalytic performance. Naturally occurring halloysite nanotubes (HNTs) are promising alternative supports for fine metal nanoparticles, but the smooth surface and single type of functional groups on HNTs are usually unfavorable for the anchoring of metal ions. Herein, we modified HNTs using a mild and controllable molten salt etching method to create a rough surface (rHNTs), followed by loading Pt–Ni alloys to prepare Pt–Ni/rHNTs for the catalytic reduction of 4-NP. The results demonstrate that ultrafine Pt–Ni alloy nanoparticles with a diameter of 1.60 nm are uniformly dispersed on the rough surface of rHNTs. The particle size and catalytic performance can be tuned by adjusting the loading amount of Pt–Ni. The optimized Pt–Ni/rHNT (1 wt %) nanocatalyst reveals the smallest Pt–Ni particle size and the highest catalytic rate of 0.1953 min−1, which exceeds many Pt–Ni-based catalysts in previous reports. This work offers an ingenious idea for the mild surface modification of HNTs and a brilliant perspective for the rational design of inexpensive 4-NP reduction nanocatalysts.
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