PLANT MOLECULAR BIOLOGY
·
2026
·Vol. 116
·期 2
·35
·
IF 3.7
Ren Fangfang,Shen Hui,Chen Weiye,Sha Siyue,Li Shanshan,Tao Xin,Li Zhuorui,Shen Weishou,Gao Nan
There is increasing interest in novel fertilizers to reduce dependency on chemical fertilizers in agriculture. Esters are promising stimulants. γ-Valerolactone, a volatile organic compound produced by Stutzerimonas stutzeri NRCB010, was suggested to promote tomato seedling growth under sterile conditions. We thus examined the effects of varying concentrations of γ-valerolactone on growth in hydroponic and greenhouse conditions, checked associated transcriptional changes, and measured the hormone contents. In this study, γ-valerolactone treatment significantly promote the tomato seedling growth, and the optimum concentration was 100 mg L − 1 and 250 mg L − 1 in hydroponic and greenhouse conditions, respectively. The content of IAA-aspartate, IAA-glutamate, indole-3-acetamide, indole-3-acetonitrile, indole-3-butyric acid, gibberellic acid 3 were all significantly increased in leaves, stem, and roots. Transcriptomic analysis revealed that when treated with γ-valerolactone for 6 h, there are more upregulated differentially expressed genes (DEGs) than downregulated DEGs, however, it’s opposite when treated with γ-valerolactone for 24 h. γ-Valerolactone may stimulate the growth of tomato seedlings through mechanisms such as photosynthesis, phytohormone signaling, and the biosynthesis of secondary metabolites. Our studies provide a theoretical basis for the application of γ -valerolactone as a new type of plant growth regulator and lay the foundation for the development of efficient and environmentally friendly agricultural biostimulants.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
WATER AIR AND SOIL POLLUTION
·
2026
·Vol. 237
·期 10
·615
·
IF 3.5
Tian Jianghao,Xiao Min,Li Shifeng,Bu Ruiying,Yang Xin,Zhang Hongling,Chen Xiaoyang
To overcome membrane permeation selectivity defects and mitigate membrane fouling, a novel nanocomposite, UiO-66-NH 2 /g-C 3 N 5 (UNCN), was designed and synthesized. Notably, this composite overcomes the inherent limitations of UiO-66-NH 2 (limited visible light absorption) and g-C 3 N 5 (low specific surface area). The optimal composite ratio was determined to be 3:7 through systematic optimization. The UNCN-3:7 nanocomposite was then embedded into the polyamide selective layer on polysulfone via in situ interfacial polymerization under optimal conditions, resulting in a thin film nanocomposite (TFN) Nanofiltration membrane. Characterization revealed that the UNCN-3:7 Nanocomposites were uniformly distributed within the polyamide (PA) matrix. The resulting TFN Nanofiltration membrane possessed an ultrathin, positively charged selective layer with enhanced hydrophilicity, evidenced by a reduction in water contact angle from 60.3° to 47.3°. It exhibited a 43% increase in pure water permeability compared to the unmodified thin film composite (TFC) membrane (52.7 vs. 36.9 L·m −2 ·h −1 ·bar −1 ), while maintaining an excellent Na 2 SO 4 retention rate (> 96%). Furthermore, the membrane demonstrated excellent photocatalytic degradation performance, superior anti-fouling properties (flux recovery rate > 92%), and stable long-term operation. These results indicate that the construction of the novel UNCN nanocomposite Nanofiltration membrane presents an effective strategy to address membrane fouling issues.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 3
·196
·
IF 5.4
Yue Xiaoyue,Hao Chenxu,Ji Jinhua,Zhang Hui,Peng Yuewen,Bai Yanhong
A dual-mode sensor integrating colorimetric and fluorescent functionalities was constructed to enable sensitive, on-site visual detection of nitrite in food matrices, with CoFeMn hydroxide nanoflowers (CoFeMn HNFs) serving as a novel oxidase-mimicking nanozyme. First, the successful synthesis of CoFeMn HNFs was confirmed through a series of characterization techniques, including scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), and X-ray photoelectron spectroscopy (XPS). Then, the synthesized CoFeMn HNFs, which exhibit remarkable oxidase-like activity, effectively catalyzed the oxidation of 3,3’,5,5’-tetramethylbenzidine (TMB) to its blue oxidized form (ox-TMB) via the generation of superoxide anion radicals (O 2 • ⁻). Its K m and V max values reached 0.399 mM and 2.8 × 10 −7 M·s −1 , respectively, demonstrating not only significantly higher catalytic activity than horseradish peroxidase (HRP) but also efficient catalysis without the requirement of H 2 O 2 . In the presence of nitrite, ox-TMB undergoes a diazotization reaction to form yellow diazo products, accompanied by a distinct fluorescence quenching effect. In the colorimetric mode, the sensor exhibited an excellent linear response to nitrite over the concentration range 0.2 to 40 µg/mL, accompanied by a limit of detection (LOD) as low as 0.063 µg/mL. For the fluorescence mode, a superior linear range of 0.3 to 40 µg/mL was achieved, with a LOD of 0.223 µg/mL nitrite. The results generated by this dual-mode sensor for real food samples were highly consistent with the reference values from the national standard method, thereby confirming its accuracy and practical utility. This work presents a versatile, reliable, and cost-effective nanozyme-based platform that addresses a critical need for sensitive, rapid, and on-site nitrite monitoring in food products, with broad implications for improving food safety surveillance and protecting public health.
Section
Graphical
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2026
·
IF 18.1
Qiao Kun,Feng Xuyang,Dong Linyu,Liu Limei,Ma Qing,Zhao Dechun,Lu Shang,Wang Haoyang,Yu Cunjiang,Pan Lijia,Wang Binghao
Vision-based robotic triaxial tactile sensing provides superior spatial resolution and rich multimodal data. However, employing rigid CMOS imagers suffers from limitations in mechanical flexibility and large-area scalability. Here we present a large-area ultraflexible photoelectrical impedance tomography (PIT)-based imager that achieves high-fidelity triaxial tactile sensing. The 5-μm-thick PIT imager incorporates a quantum dots/metal-oxide heterojunction layer with 16 peripheral electrodes, significantly reducing interconnects complexity (pixel-to-interconnect ratio >80). The device exhibits a photo-to-dark-current ratio exceeding 10⁴ under ultraviolet illumination, resolves spatiotemporal features as fine as 1.5 mm, and can simultaneously image up to five occluded regions. By integrating a thin light-scattering porous rubber and flexible LEDs, triaxial force decoding is achieved through Gaussian photocurrent analysis. The system achieves over a dynamic range of 80 kPa with a normal force sensitivity of 0.04 kPa⁻¹, a shear displacement resolution of 0.17 μm kPa⁻¹, and a topological recognition accuracy of 96.5%. We anticipate that this technology will enable advanced applications in industrial and humanoid robotics, medical and rehabilitation robotics, and wearable health monitoring and human–machine interaction systems.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOLOGICAL TRACE ELEMENT RESEARCH
·
2026
·
IF 4.3
Yang Wenyan,Ma Lu,Hu Ting,Zhang Lei,Wu Kewei,Chen Hualin,Zhang Dandan,Luo Peng
Geochemical fluoride pollution is a global public health issue affecting a wide range and large population. The major health hazard from long-term fluoride exposure is skeletal fluorosis, a highly disabling and irreversible bone damage disease with no effective early interventions available to date. Given reactive oxygen species (ROS) accumulation is a key event in fluoride-induced bone damage, we established a sodium fluoride-exposed rat model. During the phase when fluoride induced ROS accumulation and mild bone damage in rat bone tissue, we administered Rosa roxburghii Tratt juice (RRTJ)—a natural food-medicinal homologous plant with antioxidant properties—to explore its intervention effect and potential mechanism against fluoride-induced bone damage. Results showed RRTJ inhibited fluoride-induced decreases in bone mineral density and trabecular number in male rats. Since enhanced bone resorption mediated by osteoclast overactivation is the initiating link of these fluoride-induced pathological changes, this study further found RRTJ suppressed fluoride-induced increases in osteoclast activity in male rat bone tissue, specifically reducing osteoclast numbers in bone tissue and lowering serum levels of bone resorption markers CTX and TRAP-5b. This effect is achieved by RRTJ scavenging fluoride-induced ROS accumulation in bone tissue, restoring ROS/TNF-α/NF-κB pathway homeostasis, and thereby inhibiting the overexpression of osteoclast activation-related genes tartrate-resistant acid phosphatase and cathepsin K. In conclusion, this study confirms RRT inhibits fluoride exposure-induced bone damage in male rats by regulating ROS/TNF-α/NF-κB pathway homeostasis. These findings provide new perspectives on the mechanism of fluoride-induced bone damage and, more importantly, reveal a potential novel intervention strategy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CELLULOSE
·
2026
·
IF 4.6
Zhu Hong,Cheng Jun-Hu,Yi Cuiping
This study investigated the structural and performance characteristics of cellulose nanofibers (CNFs) prepared through Fe 2+ assisted cold plasma (CP) pretreatment of cellulose. The results indicated that the high-energy active particles generated by Fe 2+ assisted CP played a crucial role in the deconstruction of cellulose, resulting in CNFs with a more uniformly dispersed network structure, increased carboxyl content, and enhanced intramolecular hydrogen bonding. This effect was particularly pronounced at a working voltage of 60 kV. In addition, the mechanical properties of CNF films exhibited significant improvements in tensile strength and elongation at break. At a working voltage of 60 kV, the tensile strength and elongation at break of the CNF film increased by 21.79% and 78.91%, respectively, compared to that obtained without pretreatment. Compared to enzymatic pretreatment methods, the Fe 2+ assisted CP pretreatment offered distinct advantages in both time efficiency and mechanical performance enhancement of CNF film. Considering the overall structure and properties of the CNFs, a working voltage of 60 kV was determined to be optimal for Fe 2+ assisted CP pretreatment, yielding superior CNF performance.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2026
·
IF 1.7
Yao Benlin,Ren Guangzhi,Jia Hongwei,Yang Mingshuai,Li Xun,Liu Xiao,Sun Jing,Liu Sijing,Xiao Yiqun,Meng Zhaokai,Song Peng,Chen Hui,Zhang Qiuyue,Zhang Lei,Lin Rushan,Ye Guoan,He Hui
This study investigated the electrolytic reduction of kilogram-scale U₃O₈ pellets in molten LiCl and focused on optimizing the process for nuclear fuel cycle applications. Critical developments included resolving carbon impurity issues in LiCl, implementing a sequential kerosene-cyclohexane washing process at 150 °C for lithium anode pretreatment, and establishing optimal pellet fabrication parameters. By adjusting the sintering atmosphere, the pellet density (4.5–8.5 g/cm 3 ) and chemical composition (U₃O₈ or U₄O₉) could be controlled. The electrolytic reduction used a stainless-steel cathode basket loaded with sintered pellets and a lithium metal counter electrode. The experiment was conducted in an inert-atmosphere glove box for 181h. The results showed reduction extents of 99.09% for U₃O₈ and 99.17% for U₄O₉, a uranium metal production rate of 55.7 gU/h, and a current efficiency of 56.1%. X-ray diffraction analysis confirmed that the primary reduction products were metallic uranium and uranium carbide.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2026
·
IF 15.7
Qingming Kong,Yu Tan,Kaiqiang Zhang,Haiyang Zhang,Tengyang Zhu,Xu Wang
Thermosetting polymers are widely used for their high mechanical performance and long-term structural reliability, but their permanent crosslinked networks prevent reprocessing and recycling, leading to persistent environmental challenges. Existing dynamic covalent and supramolecular strategies offer partial solutions, yet often suffer from performance loss after repeated recycling due to incomplete reversibility and the accumulation of defects. Here, we present a strategy for the decrosslinking and upcycling of post-service thermosets based on a dynamic polyurethane network containing hindered urea bonds (HUBs). The elastic network exhibits high mechanical strength, self-healing, and thermal reprocessability. Upon exposure to small-molecule amines, the HUBs undergo exchange reactions that enable controlled network disassembly, allowing the thermosets to be transformed into reprocessable thermoplastics. The decrosslinked derivatives facilitate high-value composites—toughening glass fiber matrices by 229% through interfacial reinforcement and achieving commercial-grade electromagnetic shielding (28.1 dB) via optimized carbon nanotube integration. This molecularly engineered decrosslinking-upcycling paradigm establishes a viable pathway for circular thermoset utilization, advancing sustainable polymer technologies. Dynamically cross-linked thermosets often show decreased performance after numerous reprocessing cycles, limiting their long-term recyclability. Here, the authors introduce dynamic hindered urea bonds into polyurethane, enabling its thermal-decrosslinking and offering an upcycling route.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Probiotics and Antimicrobial Proteins
·
2026
·
IF 5.3
Zhou Xinhong,Ciwang Renzeng,Wu Dan,Cidan Yangji,Liu Guifang,Pingcuo Bandan,Luosang Cuicheng,Gusang Deji,Zhu Yanbin
This study aimed to isolate and identify a fiber-degrading probiotic strain from traditional yak yogurt on the Qinghai–Tibet Plateau and evaluate its effects on rumen fermentation and microbial metabolism. Through carboxymethyl cellulose (CMC) screening, filter paper degradation, and straw degradation tests, a lactic acid bacterium —Pediococcus pentosaceus JASB0677—was obtained, with a straw degradation rate of 18.74%. P. pentosaceus JASB0677 exhibited tolerance to simulated gastric (pH 3.0, 1% pepsin, survival rate: 69.01%) and intestinal juices (pH 8.0, 1% trypsin, 63.18%) and showed bile salt resistance at 0.1%, 0.2%, and 0.3% concentrations (survival rates: 79.05%, 63.34%, and 52.32%, respectively). It also demonstrated strong antibacterial activity, with an inhibition zone diameter of 20.03 mm against Salmonella, and antioxidant activity, with 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical scavenging rates of 46.52% and 39.17%, respectively. In vitro rumen fermentation revealed that P. pentosaceus JASB0677 significantly increased acetate and total volatile fatty acids (TVFAs) concentrations while reducing ammonia nitrogen levels ( p < 0.05). 16 S rRNA sequencing revealed that P. pentosaceus JASB0677 altered the rumen microbial composition by increasing the relative abundance of Proteobacteria , Actinobacteria , Enterobacter , Klebsiella , and Christensenellaceae_R-7_group . Metabolomic analysis revealed significant modulation of several metabolic pathways, especially those related to amino acid and lipid metabolism. Correlation analysis indicated that acetate and TVFAs concentrations were significantly positively correlated with the abundances of Proteobacteria , Actinobacteria , Enterobacter , and Klebsiella , as well as specific metabolites including mevalonic acid and L-leucine, while ammonia nitrogen showed the opposite trend ( p < 0.05). These results suggest that P. pentosaceus JASB0677 is a promising candidate functional feed additive for enhancing fiber utilization, maintaining microbial homeostasis, and improving rumen fermentation in ruminants.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2026
·
IF 18.1
Ye Yingmin,Zhang Kai,Wang Yanmin,Li Yang,Zhao Nana,Xu Fu-Jian
The rapid emergence of antimicrobial resistance is a critical global health challenge that renders conventional antibiotics ineffective. Developing innovative strategies to resensitize drug-resistant pathogens to existing antibiotics represents a promising therapeutic approach. Here, we present a biomimetic nanoplatform (Ce-Car@EV NPs) through the rational integration of ginger-derived extracellular vesicles (EVs) and a pH-responsive cerium-carbenicillin coordination nanoparticles (Ce-Car NCPs). This design enables prolonged circulation and targeted degradation in acidic infection sites, releasing Ce 4+ ions and carbenicillin. The released Ce 4+ ions penetrate the bacterial cells, where they disrupt ATP synthesis, impede oxidative phosphorylation, and inhibit the activity of efflux pump. By depleting ATP, blocking efflux pumps, and thereby reversing bacterial resistance, Ce 4+ ions act as a potent adjuvant to carbenicillin. Here we show that this strategy effectively restores carbenicillin efficacy against drug-resistant Pseudomonas aeruginosa both in vitro and in vivo, establishing a therapeutic strategy leveraging metallic adjuvants to counteract antimicrobial resistance.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CATALYSIS LETTERS
·
2026
·Vol. 156
·期 3
·75
·
IF 2.5
Huang Haiyun,Chen Lungang,Zhang Xinghua,Zhang Qi,Zhuang Xiuzheng,Ma Longlong
Effective utilization of lignocellulosic biomass as value-added fuels and chemicals is of great significance for achieving the dual goals of sustainable biorefinery and carbon neutrality. Here, Ni-WOx@C catalysts were synthesized for efficiently catalytic conversion of cellulose into ethylene glycol (EG). The catalyst was prepared through a one-step pyrolysis method by using citric acid and SiO 2 as the carbon source and structural template, respectively. A series of controlled experiments demonstrated that the pyrolysis temperature and the particle size of the SiO 2 template significantly affected the physicochemical properties of the catalyst, including the surface morphology, active sites provided by the loaded metals, and the distribution of Lewis acid sites. The optimized catalysts of Ni-WOx@C 600−2 , which was prepared by the pyrolysis at 600 °C with a 2 μm SiO 2 template, delivered the best performance characterized by its high specific surface area (124.86 m 2 /g), well-defined pores, as well as the cooperation between metallic species and Lewis acid sites. Under the optimized reaction conditions (220 °C, 4 MPa H 2 , 3 h), this as-prepared catalyst achieved nearly complete cellulose conversion (> 99%) and EG yield of 60.1%. Generally speaking, the design of Ni-WOx-based catalyst provides new insight for effective catalysis and has considerable application potential in cellulose conversion. Graphical
✓ 已验证
产品关联
DOI
高影响因子
Communications Biology
·
2026
·
IF 5.8
Liu Junyu,Fang Zhihao,Li Xiaobin,Zhang Xiaopeng,Chen Yun,Kou Fujia,Huang Long,Yang Huanxian,Zheng Yilin,Huang Yuqing,Wang Yi,Qiu Xueqing,Ge Jun,Qian Yong,Xing Xin-Hui,Zhang Can Yang
Oral probiotics have shown great potential in treating ulcerative colitis (UC). However, gastrointestinal obstacles substantially inactivate probiotics, impeding delivery and colonization in the colon. Here, we developed robust oral living therapeutics with high colon-accumulating effect via surface decoration of probiotic ( Escherichia coli Nissle 1917, EcN ) using a layer-by-layer approach. Calcium ions and carboxymethyl-modified lignin (CML) were sequentially coated on EcN to generate an acid-resistant and colitis microenvironment-responsive system (CML@ EcN ). After oral administration in a male C57BL/6 N mouse model, EcN were specifically delivered to the site of colitis and successfully colonized. The CML@ EcN notably alleviated colitis by modulating immune dysfunction, reshaping gut microbiota (GM), and repairing the intestinal barrier. The delivery mechanism was explored based on experiments and mathematical models. Interestingly, this engineering approach can be further used to decorate other bacteria. Consequently, the robust CML@ EcN shows high colon-targeting delivery efficacy and great potential in UC therapy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）