INORGANIC CHEMISTRY COMMUNICATIONS
·
2025
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IF 5.4
Kaikai Xu,Lulu Kong,Kebin Ye,Beibei Xu,Yongming Deng,Yicheng Wang,Shaohua Wei
Phthalocyanine (Pc) is a promising class of metalloantibiotics with antibacterial properties, akin to many metalloantibiotics, that exerts its effect by disrupting the bacterial respiratory chain. Therefore, it is particularly crucial to develop simple and efficient antibacterial strategies to enhance the activity of antibiotics. The construction of metal–organic frameworks (MOFs) helps to improve the electron transfer ability of phthalocyanine antibacterial drugs and enhance their antibacterial activity. In this study, we report the synthesis of a two-dimensional (2D) NiPc-Cu MOF using a modified liquid–liquid interfacial method, offering a facile, scalable, and stable approach. The excellent electron transfer properties of the MOF significantly enhance the ability of NiPc to disrupt the respiratory chain, thereby boosting its antibacterial activity. Compared to NiPc alone, NiPc-Cu MOF demonstrated a 1000-fold reduction in the minimum inhibitory concentration (MIC 50 ) against Escherichia coli ( E. coli ), reaching 4 ng/mL—a level surpassing most reported metalloantibiotics and comparable to clinically used antibiotics. Furthermore, NiPc-Cu MOF selectively targets bacteria with minimal cytotoxicity to animal cells. Based on this, we have developed NiPc-Cu MOF as a safe antibacterial coating for catheters, characterized by excellent stability and superior antibacterial activity. This study provides a straightforward and effective strategy for enhancing the activity of molecular drugs that exert antibacterial effects by interfering with the respiratory chain.
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JOURNAL OF HAZARDOUS MATERIALS
·
2017
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IF 6.065
Weirui Chen,Xukai Li,Yiming Tang,Jialu Zhou,Dan Wu,Yin Wu,Laisheng Li
A flexible catalyst, Fe-Cu-MCM-41, was employed to enhance diclofenac (DCF) mineralization and inhibit bromate formation in catalytic ozonation process. Greater TOC removal was achieved in Fe-Cu-MCM-41/O 3 process (78%) than those in Fe-MCM-41/O 3 (65%), Cu-MCM-41/O 3 (73%) and sole ozonation (42%). But it was interesting that both Cu-MCM-41/O 3 and Fe-MCM-41/O 3 achieved 93% bromate inhibition efficiency, only 71% inhibition efficiency was observed in Fe-Cu-MCM-41/O 3 . Influence of pH, TBA/NaHSO 3 and detection of by-products were conducted to explore the mechanism. By Pyridine adsorption–IR and XPS, a relationship was found among activity of catalysts, Lewis acid sites and electron transfer effect between Fe (II/III) and Cu (I/II). Fe-Cu-MCM-41 promoted ozone decomposition to generate OH, which accounted for enhanced DCF mineralization. The consumption of aqueous O 3 also suppressed the oxidative of Br − and HBrO/Br − . More HBrO/BrO − accumulated in catalytic ozonation process and less bromate generated. Bromate formation in Fe-Cu-MCM-41/O 3 process was sensitive with pH value, the acidic condition was not favor for bromate formation. Both DCF mineralization and bromate inhibition were influenced by surface reaction. Moreover, Fe-Cu-MCM-41 showed excellent catalytic performance in suppressing the accumulation of carboxylic acid, especially for oxalic acid. Nearly no oxalic acid was detected during Fe-Cu-MCM-41/O 3 process.
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JOURNAL OF NANOPARTICLE RESEARCH
·
2017
·Vol. 19
·期 12
·1-9
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IF 2.02
Huang Shan,Pang Guangming,Li Xiangkui,Li Jianping,Pan Hongcheng
Metal-hydroxyquinoline-halogen (MqX, M = Cd, Cu; q = 8-hydroxyquinoline; X = Cl, Br, I) nanowires are synthesized via a sonochemical-assisted method. The elemental analysis (EA), inductively coupled plasma-optical emission spectroscopy (ICP-AES), and X-ray photoelectron spectroscopy (XPS) support an M/q/X ratio of 1:1:1. The electron microscope images reveal a typical CdqX and CuqX nanowire diameter of 30–50 nm and a nanowire length of 400–600 nm. In addition, the synthesis of the MqX nanowires is only observed when there is an excess of halide ions (X/q molar ratio of 3 or greater). This halide deficiency results in the formation of micrometer-sized Mq 2 sheets. We demonstrated the conversion of the MqX nanowires to Mq 2 micro-sheets in an ultrasonic bath of 1 M 8-Hq ethanol solutions (50%, w / w ) at 50 °C for 2 h, but not vice versa. The MqX nanowires exhibited excellent properties for photoluminescence, electrochemiluminescence (ECL), and photoelectrochemistry (PEC). The CdqBr and CdqI nanowires were coated onto a glass carbon and a fluorine-doped tin oxide glass electrode to develop the above ECL and PEC methods for the detection of H 2 O 2 and Cu 2+ , respectively. In the range of 2 to 14 μM, the ECL intensity of the CdqBr nanowires was inversely proportional to the concentration of H 2 O 2 with a detection limit of 0.26 μM. For Cu 2+ sensing, the photocurrent of the CdqI nanowires exhibited a linear response to Cu 2+ over the range of 2 to 16 μM of which a detection limit of 0.2 μM was observed.
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TALANTA
·
2018
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IF 4.244
Xuemei Wang,Xiaomin Ma,Pengfei Huang,Juan Wang,Tongtong Du,Xinzhen Du,Xiaoquan Lu
Hybrid magnetic nanocomposites based on Cu-MOFs, graphene oxide (GO), and Fe 3 O 4 nanoparticles (NPs) were prepared via chemical bonding approach, which GO were used as platforms to load nanostructured Cu-MOFs and Fe 3 O 4 NPs. The composite features both magnetic separation characteristics and high MOFs porosity, making it an excellent adsorbent for magnetic solid-phase extraction (MSPE). The as-synthesized nanocomposites are characterized by XRD, TGA , SEM, TEM, nitrogen adsorption-desorption analysis and FT-IR spectroscopy. The composites are used in MSPE of six aromatic insecticides from various real samples prior to their quantification by HPLC . Amount of adsorbent, extraction times, extraction temperature, desorption times and oscillation rate are optimized. Under the optimal conditions, the method has a relative standard deviations (RSDs) of 1.9–2.7%, and good linearity (correlation coefficients higher than 0.9931). The low LOD and LOQ for six insecticides are found to be 0.30–1.58 μg L -1 and 1.0–5.2 μg L -1 , respectively. The RSDs of within batch extraction are 1.6–9.5% and 3.9–12% for batch to batch extraction. The experimental results suggest that the nanocomposites have potential application for removal of hazardous pollutants from effluents.
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APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Miao Sun,Xiao Xu,Shihao Min,Jiaxin He,Kun Li,Longtian Kang
Copper-based metal-organic framework (Cu-MOF) materials with multiple active sites have attracted increasing attention to the electrocatalytic CO 2 reduction reaction (ECR), however, face the huge challenge owing to the poor stability and low C 2 selectivity. Here, the Cu 2 O/Cu-CuTCPP heterojunction (Cu 2 O/CPFs) with three Cu active sites are firstly constructed through in-situ electrodeposition method. The effect of CuSO 4 concentration and electrodeposition conditions on ECR is systematically investigated. The optimized Cu 2 O/CPFs composite achieves the ethylene Faraday efficiency (FE C2H4 ) of 61.8 % at –1.3 V vs. RHE, which is 1.9 and 3.42 times higher than those of CPFs and Cu 2 O, respectively. Meanwhile, the C 2 H 4 partial current density ( j C2H4 ) of –7.96 mA·cm −2 is 2.91 and 4.68 times higher than those of CPFs and Cu 2 O. Further experiments reveals that the formation of Cu 2+ –O–Cu + –O bond between Cu 2 O and Cu–O 4 sites in Cu 2 O/CPF heterojunction is crucial. Consequently, the hydrogen (H 2 ), formic acid (HCOOH) and methane (CH 4 ) evolution reactions are restricted, the C–C coupling reaction of *CHO and *CO intermediates is significantly enhanced, and the Cu–O 4 sites in CPFs are protected. This work provides an effective strategy to stabilize MOF structure and obtain high value-added C 2+ products.
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Scientific Reports
·
2024
·Vol. 14
·期 1
·1-15
·
IF 3.8
Yue Jiayuan,Zheng Qi,Ding Shushu,Yin Yujian,Zhang Xiaodan,Wang Liyun,Gu Yipeng,Li Jiejia,Zhang Yuhan,Shi Yurou,Dong Yuetan,Zhu Qing,Duo Huixiao
In this study, the removal effect of a new MOF-on MOF adsorbent based on Cu–Co bimetallic organic frameworks on tetracycline antibiotics (TCs) in water system was studied. The adsorbent (Cu-MOF@Co-MOF) were synthesized by solvothermal and self-assembly method at different concentrations of Co 2+ /Cu 2+ . The characterization results of SEM, XRD, XPS, FTIR and BET indicated that the MOF-on MOF structure of Cu-MOF@Co-MOF exhibited the best recombination and physicochemical properties when the molar ratio of Co 2+ : Cu 2+ is 5:1. In addition, the Cu-MOF@Co-MOF have a high specific surface area and bimetallic clusters, which can achieve multi-target synergistic adsorption of TCs. Based on above advantages, Cu-MOF@Co-MOF provided a strong affinity and could efficiently adsorb more than 80% of pollutants in just 5 to 15 min using only 10 mg of the adsorbent. The adsorption capacity of tetracycline and doxycycline was 434.78 and 476.19 mg/g, respectively, showing satisfactory adsorption performance. The fitting results of the experimental data were more consistent with the Langmuir isotherm model and pseudo-second-order kinetic model, indicating that the adsorption process of TC and DOX occurred at the homogeneous adsorption site and was mainly controlled by chemisorption. Thermodynamic experiments showed that Cu-MOF@Co-MOF was thermodynamically advantageous for the removal of TCs, and the whole process was spontaneous. The excellent adsorption capacity and rapid adsorption kinetics indicate the prepared MOF-on MOF adsorbent can adsorb TCs economically and quickly, and have satisfactory application prospects for removing TCs in practical environments. The results of the study pave a new way for preparing novel MOFs-based water treatment materials with great potential for efficient removal.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Xinrui Han,Geng Li,Weiyan Su,Xusheng Xu,Mengjiao Yu,Guangyu Wu,Weinan Xing
The degradation of recalcitrant antibiotics through the activation of peroxymonosulfate (PMS) is an important branch of advanced oxidation processes (AOPs), with widespread attention given to the application of metal-organic frameworks (MOFs) in this field. The article successfully synthesized Cu x O/N-doped carbon/Cu-MOF (Cu x O/NC/Cu-MOF) nanocomposites by low-temperature thermal treatment of Cu-MOF precursors. Compared with the original MOF, these partially decomposed composite materials exhibit significantly stronger catalytic activity towards PMS, efficiently removing organic pollutants such as tetracycline (TC). After optimization, the sample treated at 400 °C, under visible light with PMS assistance, achieves an impressive degradation rate, almost completely degrading a 50 mL TC solution (10 mg/L) after 80 min. This achievement surpasses the degradation rate observed with the original Cu-MOF by 2.1 times. In the composite system of Cu x O/NC/Cu-MOF+PMS+Vis, the significant enhancement of activity is credited to the effective spatial separation of photogenerated electrons and holes, as well as the utilization of 1 O 2 as the primary active oxygen species. This work provides a simple preparation strategy for the development of Cu-based PMS activators with excellent photocatalytic performance.
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TALANTA
·
2024
·
IF 5.6
Xiupei Yang,Xiaoyi Xie,Ling Jiang,Yuxiu Fan,Chenglin Zhang,Ya Wang
Most conventional nanozymes have poor specificity and low activity, and designing high-performance nanozymes remains a challenge. In contrast, single-atom nanozymes have high atom utilization and high reactivity. Here, we prepared Cu single-atom nanozymes (Cu-NC) with excellent peroxidase-like activity by high-temperature pyrolysis using Cu as a transition metal source. The introduction of Cu formed the Cu-N x active site, which accelerated charge transfer between the reactants and the active site and was the key for improving the activity. With Cu-NC as a catalyst, H 2 O 2 rapidly oxidized 3,3′,5,5′-tetramethylbenzidine (TMB) to oxTMB, and the solution turned blue with strong absorption at 652 nm. Because d -penicillamine (D-PA) can reduce oxTMB or react with reactive oxygen species radicals to inhibit the color reaction, we built a colorimetric sensing platform around Cu-NC for the determination of D-PA and successfully used it for the determination of D-PA in urine samples. This work provides new ideas for the design of high-performance nanozymes and the detection of D-PA in real environments.
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Materials Today Chemistry
·
2024
·
IF 6.7
Yiting Jiang,Zhejie Chen,Yating Yuan,Linxin Tian,Chuhuang Dong,Wencheng Shen,Jinchao Wei,Shengpeng Wang,Yu Yang,Jia Ge
Alpha-glucosidase (α-Glu) is a hydrolase that promotes the rise of glucose in the blood during the digestion process, and it plays a crucial role in regulating glucose levels within a normal range. Herein, we developed an ultrasensitive colorimetric platform by preparing a Cu–N–C single-atom nanozyme (Cu–N–C SAzyme) with a potent oxidase-like effect on accurately detection of α-Glu and efficient screening of its potential inhibitors. This artificial nanoenzyme was able to catalyze the oxidation of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) to blue oxide (oxTMB) without the assistance of H 2 O 2 . In addition, with the participation of α-Glu, l -ascorbic acid-2- O -α- d -glucopyranose (AAG) can be catalyzed to produce ascorbic acid (AA), which significantly reduces the oxidation, resulting in a noticeable fading of the blue color. Therefore, we designed a straightforward colorimetric test for α-Glu activity, achieving detection limits as low as 0.09 U/L and a linear response from 0.25 to 8 U/L. Most importantly, this platform has been effectively applied to measure α-Glu in real samples.
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ACS Sensors
·
2024
·
IF 8.2
Huan Wang,Chonghui Zhu,Xiaohui Yan,Zhaorui Zhang,Huashuai Hu,Mengmeng Xu,Yu Liang,Minghui Yang
Fuel cell gas sensors have emerged as promising advanced sensing devices owing to their advantageous features of low power consumption and cost-effectiveness. However, commercially available Pt/C electrodes pose significant challenges in terms of stability and accurate detection of low concentrations of target gases. Here, we introduce an efficient Cu–Pt/CrN-based fuel cell gas sensor, designed specifically for the ultrasensitive detection of hydrogen sulfide (H2S) at room temperature. Compared to the commercial Pt/C sensor, the Cu–Pt/CrN sensor exhibits excellent sensitivity (0.26 μA/ppm), with an increase in the selectivity by a factor of 2.5, and demonstrates good stability over a 2 month period. The enhanced sensing performance can be attributed to the modulation of the electronic arrangement of Pt by Cu, resulting in an augmentation of H2S adsorption. The Cu–Pt/CrN fuel cell gas sensor provides an opportunity for detecting parts per billion-level H2S in various applications.
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Small
·
2025
·
IF 12.1
Min Zhu,Ting Zhang,Jinlong Wu,Xiuli Wang,Jin Zhang,Feng Li,Jing Li
Lattice strain is widely recognized as an effective strategy for tuning transition metal catalytic activity, yet its direct impact on electrochemical CO₂ reduction (ECO₂RR) remains not fully understood. In this work, a strategy of Cu-doped Ag is employed to construct a series of AgCu nanosheet structures (NS) with varying lattice compression rates (from −1.90% to −2.75%). Density Functional Theory (DFT) calculations, along with in situ infrared spectroscopic analysis, demonstrate that Cu incorporation efficiently modulates the electronic structure of Ag, promoting enhanced charge transfer. Especially, the changed lattice compression rates can alter the charge density at adsorption sites, thereby ameliorating the surface coverage of CO and adsorption energy of the reaction intermediates ( * COOH and * CO). As a result, the AgCu 5% catalyst exhibits a maximum Faradaic efficiency (FE) of 95.5% for CO production in an H-cell and 98% in a flow cell at −0.8 V RHE , respectively. Simultaneously, the AgCu 5% catalyst achieves FE CO of above 86% in the ultrawide current range of 33–215 mA cm −2 . The work affords an effective way to use a strain compression strategy to improve the CO 2 reduction performance.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2024
·
IF 20.2
Lixin Song,Guobin Liu,Zhenping Qu
Cu/ZnAl 2 O 4 spinel is a promising catalyst for CO 2 -to-methanol due to its dual-site H 2 activation. However, controlling surface properties and metal-support interactions (MSI) through the coordination environment of spinel cations remains underexplored. Herein, the occupancy of Zn 2+ and Al 3+ cations in Cu/ZnAl 2 O 4 spinel is fine-tuned by manipulating the calcination atmosphere. More disordered structures (AlO 4 and ZnO 6 ) observed on the CZA-Ar catalyst benefit the creation of oxygen vacancies and surface hydroxyl groups, which facilitate the formation of highly dispersed small-sized Cu species. This enhances MSI and hydrogen spillover effects, thereby boosting CO 2 conversion and the space-time yield (STY) of methanol. High-pressure in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) results reveal that the crucial formate intermediates form at tetrahedral sites in ZnAl 2 O 4 spinel, with more Al-HCOO - species observed on the CZA-Ar catalyst due to the formation of AlO 4 . This work advances the understanding of spinel catalysts in CO 2 hydrogenation to methanol.
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