Biomaterials Science
·
2024
·
IF 5.8
Yongzhi Chen,Qiuxia Tan,Yuanyu Tang,E. Pang,Rui Peng,Minhuan Lan,Dousheng Bai
Hepatocellular carcinoma (HCC) is characterized by a high degree of malignancy and mortality. Sorafenib (SOR), a multi-kinase inhibitor, is clinically used in the treatment of HCC. However, SOR suffers from serious side effects and drug resistance. The development of novel therapeutic strategies for HCC therapy is urgently needed. Sonodynamic therapy (SDT) has unique advantages in treating deep tumors due to the merits of deep tissue penetration, low side effects, and the absence of drug resistance. Here, we developed multifunctional nanoparticles (NPs) termed SOR-TCPP@PEG-FA by assembling SOR, tetrakis (4-carboxyphenyl) porphyrin (TCPP), and folic acid (FA)-modified DSPE-PEG. The FA group enhances the tumor targeting capability of these NPs, while TCPP generates ROS under ultrasound (US) irradiation, which are toxic to tumor cells, and SOR with chemotherapeutic effects is released, thus realizing the synergistic SDT and chemotherapy of tumors.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2024
·
IF 8
Yijie Wang,Yue Huang,Yan Zhang,Henan Wang
Staphylococcal enterotoxins as common bacterial toxins can bring about food contamination and lead to severe foodborne illnesses, so facile and sensitive detection of staphylococcal enterotoxins is significant to ensure food safety and protect public health. In this work, an ultrasensitive biosensor for staphylococcal enterotoxin B (SEB) detection is developed based on the novel electrochemical nanoprobe named MXene/AgNPs@pSC4/MB, which is prepared by functionalizing MXene with para-sulfonatocalix[4]arene-decorated silver nanoparticles (AgNPs@pSC4) and electroactive signal molecules methylene blue (MB). The collaborative effect of AgNPs and MXene endows the fabricated electrochemical nanoprobe with excellent conductivity and admirable loading capacity of signal molecules to significantly enhance the response of biosensor, while pSC4 as the robust linker can bridge the nanoprobe and target SEB by binding with multifarious amino acid residues on SEB. With the specific aptamer immobilized on the electrode as the identifying element to capture SEB, the electrochemical nanoprobes MXene/AgNPs@pSC4/MB are anchored to SEB via pSC4, producing remarkably amplified signal output. The proposed electrochemical biosensor facilitates the ultrasensitive detection of SEB with a low detection limit of 1.76 × 10 −7 ng/mL in addition to the merits of facile operation and rapid response. Moreover, benefiting from the high chemical stability and good resistance to fouling and passivation of the electrochemical nanoprobe, the biosensor exhibits long-lasting stability, good accuracy and anti-interference ability in SEB detection. The reliable detectability of the biosensor has also been examined in the analysis of real food samples, demonstrating potential application toward food safety monitoring.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Irfan Ijaz,Aysha Bukhari,Ezaz Gilani,Ammara Nazir,Hina Zain,Attia Shaheen,Mohammed Rafi Shaik,Mujeeb Khan,Mohamed E. Assal
A rising quantity of drugs has been discharged into the aquatic environment, posing a substantial hazard to public health. In the current work, a novel hydrogel (i.Carr@Bent@PTC), comprised of iota-carrageenan, bentonite, and 4-phenyl-3-thiosemicarbazide, was successfully prepared. The introduction of 4-phenyl-3-thiosemicarbazide and bentonite in iota-carrageenan significantly increased the mechanical strength of iota-carrageenan hydrogel and improved its degree of swelling, which can be attributed to the hydrophilic properties of PTC and Bent. The recorded contact angle was 70.8°, 59.1°, 53.9°, and 34.6° for pristine i.Carr, i.Carr@Bent, and i.Carr@Bent@PTC, respectively. The low contact angle measurement of the Bent and PTC loaded-i.Carr hydrogel was attributed to the hydrophilic Bent and PTC. The ternary i.Carr@Bent@PTC hydrogel demonstrated broad pH adaptability and excellent adsorption capacities for sulfamethoxazole (SMX) and losartan potassium (LP), i.e., 467.61 mg. g −1 and 274.43 mg. g −1 at 298.15 K, respectively. The pseudo-first-order (PSO) model provided a better fit for the adsorption kinetics . The adsorption of SMX and LP can be better explained by employing the Sips and Langmuir isotherm models. As revealed by XPS and FTIR investigations, π-π stacking, complexation, electrostatic interaction , and hydrogen bonding were primarily involved in the adsorption mechanisms.
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Catalysts
·
2025
·Vol. 15
·期 2
·175
·
IF 4
Wei Wang,Jiaqi Liu,Guang Shi,Shiqi Wu,Shihan Zhang,Ruixia Yuan
A magnetic shell-structured nano-catalyst was prepared by self-polymerization of dopamine wrapped by ferric oxide as the carrier, which was loaded with palladium nanoparticles (Pd/PDA@Fe3O4). The presence of magnetic Fe3O4made it easy for nanoscale palladium particles to recover and prevent the loss of palladium nanoparticles that is unavoidable in traditional usage and preparation procedures. The catalyst was characterized by X-ray diffraction, fourier transform infrared spectroscopy, scanning electron microscopy, thermal weight loss analysis, Raman spectroscopy, X-ray photo-electron spectroscopy, and magnetic properties analysis. The catalytic performance of the prepared catalyst was investigated taking 4-nitrophenol (10 mg/L) and rhodamine B (15 mg/L) as the target pollutants. The results showed that under the conditions of 35 °C, pH = 7 and a catalyst dosage of 3 mg, the catalytic reduction efficiency of 4-nitrophenol, rhodamine B, and the mixture of them all can reach 99%. The catalytic efficiency of Pd/PDA@Fe3O4remained above 90% after being used 10 times. The shell structure of Fe3O4made it possible and easy to recover and recycle the nanoscale palladium, which was a real problem in the usage of nano-catalysts. At the same time, the problem of separation and recovery of palladium nano-catalyst is solved by magnetism, which provides research ideas for the recycling and utilization of nano-materials.
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Advanced Energy Materials
·
2024
·
IF 24.4
Ang Liang,Yue Jian,Yun Zhao,Shuo Chen,Jun Zhao,Zhuanghao Zheng,Jingting Luo,Hongli Ma,Xianghua Zhang,Zhenghua Su,Guangxing Liang
Enhancing the efficiency of Cu 2 ZnSn (S, Se) 4 (CZTSSe) thin-film solar cells requires the development of well-crystallized light-absorbing layers. A deep understanding of the role of precursor solution chemistry in film nucleation and crystal growth processes is essential. Insights into these processes enable the development of innovative strategies to enhance absorber quality, minimize detrimental bulk defects, and ultimately improve device performance. This study elucidates the condensation reactions between thiourea and metal cations, as well as the alcoholysis of 2-methoxyethanol (MOE), at different concentrations of precursor solutions. The primary focus of this study is implementing a simple and environmentally friendly innovative spin-coating strategy, aimed at optimizing Cu 2 ZnSnS 4 (CZTS) precursor films and adjusting the Se content within the film bulk to promote grain growth during selenization. This strategy effectively improves absorber morphology while suppressing the formation of deep-level defects, thereby enhancing carrier transport in both interfacial and bulk regions of the absorber layer. Consequently, CZTSSe absorbers with enhanced crystallinity and reduced defects are synthesized, resulting in a solar cell with an impressive efficiency of 14.10%. These findings underscore the potential for creating highly efficient kesterite CZTSSe solar cells through the manipulation of precursor solution chemistry using environmentally friendly solvents.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2025
·
IF 21.1
Xin-jie Zhao,Ying-jie Sun,Wei-hong Chai,Xiao-jing Wang,Jun Zhao,Yu-pei Li,Fa-tang Li
The spatial photoinduced charge separation and atomic H 2 evolution active site is decisive in the operating efficiency of the photocatalytic hydrogen evolution reaction, yet its rational design and synthesis remain a grand challenge. Here, a series of Hofmann-type coordination polymers (HCPs) with planar anionic block [Ni(CN) 4 ] 2- units were found to effectively enhance the photocatalytic H 2 evolution reaction (PHER) activity of transition metal sulfides (TMSs). This proof-of-concept study investigated four HCPs with planar anionic block [Ni(CN) 4 ] 2- units combined with different central transition metal ion (M 2+ : Ni, Co, Fe, and Mn). All four HCP-modified TMSs exhibited remarkable PHER activity of more than 20.0 mmol g −1 ·h −1 and an apparent quantum yield of ∼20 %, surpassing that of optimized Pt/Zn 0.5 Cd 0.5 S by more than 1.5-fold. Through spectroscopic characterization, Kelvin probe force microscopy (KPFM), and density functional theory (DFT) simulations, we confirmed that the [Ni(CN) 4 ] 2- units potentially bridged with the TMSs via an M-S bond forming an electronic transmission channel, thus eliminating the interface energy barrier. Due to the appropriate band structure, the photogenerated electrons converged to the [Ni(CN) 4 ] 2- units, consequently facilitating the conversion of H + to H 2 . This work demonstrates a rational synthetic route for creating PHER photocatalysts that possess mild synthesis conditions, efficient electronic transmission interfaces, and an active center that can be finely manipulated.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Shijie Liu,Qian Ding,Lijun Zhao,Yueyv Bai,Miaoyun Li,Jong-Hoon Lee,Yaodi Zhu,Yijing Ding,Lingxia Sun,Yanxia Liu,Yangyang Ma,Dong Liang
In order to realize rapid identification of different species of lactic acid bacteria and rapid quantitative detection of mixed lactic acid bacteria. In this study, L. plantarum Y1 and P. pentosaceus Z1 were used as research subjects, and AuNPs@4-MBA was prepared as the SERS substrate material for the acquisition of SERS spectra of different species of lactic acid bacteria and the construction of taxonomic identification models and SERS digitized quantitative equations. The results showed that the enhancement factor of AuNPs to 4-MBA was 3.08 × 10 2 , and the reproducibility was excellent ( RSD < 10 %). With AuNPs@4-MBA as the base material, the differences of SERS peaks between L. plantarum Y1 and P. pentosaceus Z1 could be clearly distinguished. Principal component analysis (PCA) and cluster analysis (LDA) could completely visually classify and identify different species of lactic acid bacteria. The SERS quantitative equation y = 7509.32×-5942.69, R 2 = 0.99 and the detection limit lower than 10 CFU/mL was determined by the construction of SERS detection and quantitative model for different ratios and concentrations of mixed lactic acid bacteria. In the complex environment matrix, the detection accuracy of mixed lactic acid bacteria by this method reached 96.34 % to 103.54 %. It provides a promising technical strategy for rapid qualitative and real-time quantitative monitoring of mixed lactic acid bacteria.
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JOURNAL OF MATERIALS SCIENCE
·
2014
·Vol. 49
·期 20
·7181-7191
·
IF 2.305
Mu Bin,Zhang Wenbo,Wang Aiqin
A novel superparamagnetic gold/halloysite nanotubes/Fe 3 O 4 (Au/HNTs/Fe 3 O 4 ) nanocomposite with coaxial structure was designed and fabricated by selective decoration of the inner lumen and the external wall of halloysite nanotubes (HNTs) based on the difference inside/outside surface charges. The structure and composition of Au/HNTs/Fe 3 O 4 were characterized by transmission electron microscope, powder X-ray diffraction, and X-ray fluorescence. The results indicated that Au nanorods selectively generated within the lumen of HNTs, while Fe 3 O 4 nanoparticles uniformly deposited on the external wall. It was particularly worth mentioning that the structure of HNTs was not destroyed in the preparation process of Au/HNTs/Fe 3 O 4 nanocomposites. The catalytic activity of the as-prepared Au/HNTs/Fe 3 O 4 was investigated for the reduction of 4-nitrophenol in the presence of NaBH 4 . The Au/HNTs/Fe 3 O 4 nanocomposites exhibited excellent catalytic activity and cycling stability according to the kinetic data of the catalytic reduction reaction. In addition, the Au/HNTs/Fe 3 O 4 catalysts can be easily manipulated by an external magnetic field for recycling.
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APPLIED SURFACE SCIENCE
·
2016
·
IF 3.15
Ruixin Ma,Fan Yang,Shina Li,Xiaoyong Zhang,Xiang Li,Shiyao Cheng,Zilin Liu
CZTSSe is an important earth abundant collection of materials for the development of low cost and high efficiency thin film solar cells. This work developed a simple non-vacuum-based route to fabricate CZTSSe absorber films. This was demonstrated by first synthesizing Cu 2 ZnSnS 4 (CZTS) nano-crystalline based on solid-phase synthesis. Then a stable colloidal ink composed of CZTS nano-crystalline was blade coated on Mo-coated substrates followed by an annealing process under Ar atmosphere. After CZTS films formation, the films were sintered into CZTSSe absorber films by exposing them under Selenium vapor. The formation of a kesterite type CZTS was confirmed using X-ray diffraction and Raman scattering measurements. The band gap of CZTSSe absorber films was determined to be 1.26 eV, which was appropriate for use as an absorber layer in thin film solar cells. The CZTSSe absorber films showed a good photovoltatic performance, demonstrating this simple approach had great potential for CZTSSe solar cell production.
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DALTON TRANSACTIONS
·
2022
·Vol. 51
·期 31
·11703-11712
·
IF 4.569
Jun Sun,Minghui Zhou,Bei Zhang,Youjie Hua,Feifei Huang,Hongping Ma,Renguang Ye,Shiqing Xu
A series of Rb1−yKyNa3(Li3SiO4)4:Eu2+(0 ≤ y ≤ 1) phosphors were successfully synthesized through a high-temperature solid-state reaction. The introduction of K+ into the RbNa3(Li3SiO4)4:Eu2+ phosphor to partially or completely replace Rb+ allows the emission spectrum to be modulated from blue (λ = 473 nm, FWHM = 22.5 nm) to a narrow cyan band (λ = 485 nm, FWHM = 21.1 nm). As the K+ ion content increases, the space group of the phosphor evolves from I4/M to I41/A. The complete replacement of Rb+ by K+ results in the KNa3(Li3SiO4)4:Eu2+ cyan phosphor, which shows excellent thermal stability (the comprehensive emission loss is only 8% at 150 °C) and can be used to fill the cyan light gap in white LED devices. By adding the KNa3(Li3SiO4)4:Eu2+ cyan phosphor in packaging with yellow and red phosphors, the color rendering index is increased from 90.2 to 97.1 and the correlated color temperature improved to 3658 K. These results indicate that the cyan phosphor has important application value in full-spectrum white LEDs.
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SOLID STATE IONICS
·
2019
·
IF 2.886
Guangping Chen,Chaoqun Niu,Yubing Chen,Wenyan Shang,Yanyu Qu,Zhi Du,Lingzhu Zhao,Xiaoxue Liao,Jie Du,Yong Chen
Lithium metal anode is regarded as promising potential electrode for next-generation secondary batteries. However, the security issues caused by the growth of lithium dendrites hinder the development of lithium metal batteries . In this study, we prepare a single-ion conducting polymer electrolyte with semi-interpenetrating polymer network based on poly(lithium 4-styrenesulfonate). By eliminating the large electric fields near the lithium anode, the growth of lithium dendrite is suppressed effectively according to space-charge theory. The structurally optimized poly(lithium 4-styrenesulfonate)@polymethylmethacrylate single-ion conducting polymer electrolyte containing 2 wt% ethylene glycol dimethacrylate exhibits extremely high lithium ion transference number (0.91), promising ionic conductivity (0.97 × 10 −3 S cm −1 at 25 °C) along with wide electrochemical window of 4.7 V (vs. Li + /Li). Furthermore, the LiFePO 4 /membrane/Li cell achieves stable cycling performance (capability retention rate of 93.8% after 78 cycles at 1 C (1 C = 170 mAh g −1 ) and high coulombic efficiency 99.4%) along with superior discharge rate capability at room temperature . These excellent performances show that the single-ion conducting polymer electrolyte is a potential candidate for safe lithium metal batteries .
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Journal of Materials Chemistry C
·
2022
·Vol. 10
·期 41
·15638-15646
·
IF 8.067
Xiang Li,Xinghuan Hu,Hua Liao,Shuai Yang,Xinyu Li,Qiulian Li,Xin Liu,Yonggang Zhao,Shurong Wang
In this study, a simple and reproducible two-step annealing process was demonstrated to prepare Cu2ZnSn(S,Se)4 (CZTSSe) thin film with band-gap grading by selenization followed by post-sulfo-selenization (PSS) treatment. The effects of PSS treatment on the composition and electrical properties of the CZTSSe thin film were investigated. The crystal structure, surface morphology, surface roughness and element composition of the CZTSSe thin film were characterized by GIXRD, SEM, AFM and EDS tests. The composition of elements at different depths of the thin film was also investigated. It was confirmed that CZTSSe thin film with high sulfur element content on the surface and low at the bottom were obtained after PSS treatment. The electrical performance of the CZTSSe solar cells was measured by Hall test, EQE and J–V. The results showed that the power conversion efficiency (PCE) of the CZTSSe thin film without PSS treatment was only 7.62%, while the PCE of the CZTSSe thin film after PSS treatment increased to 10.11%.
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