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JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE · 2026 · IF 3.4

Comparative analysis of the effect of processing techniques on purines in tofu products

Agbekponou Michelle Djelim Grace,Xiao Lu,Hou Chuanli,Ma Wenjing,Xu Zhenzhen,Amakye William Kwame,Ren Jiaoyan

Food processing techniques could have profound effect on the purine content and availability in different foods. Although tofu is generally regarded as a low purine food with very minimal impact on serum uric acid levels, different production techniques could significantly impact the purine content. The study examined the purine content in minimally processed and deep-processed tofu products, using High-Performance Liquid Chromatography (HPLC) and further determined differences in purine content per unit protein in different types of tofu. Results showed that minimally processed tofu was generally low purine content (9.73 ± 0.05 ~ 48.74 ± 2.79 mg/g), while deep-processed tofu could be classified as medium or high purine content (65.74 ± 5.25 ~ 121.18 ± 2.55 mg/g). Dried (121.18 ± 2.55 mg/g) and fried (106.03 ± 0.97 mg/g) tofu were highest in purine content suggesting increased consumption could pose risk for serum uric acid levels. Yuba (1.45 ± 0.12 mg/100g) showed the lowest purine content/protein unit and could be ideal as protein source for individuals at risk of hyperuricemia. This study provides empirical evidence which could be vital for planning healthy dietary choices with tofu for managing gout and hyperuricemia.

CAS / MDL: 76-05-1
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MICROCHIMICA ACTA · 2026 ·Vol. 193 ·期 3 ·128 · IF 5.4

Immunochromatographic SERS sensor-deep learning combined strategy for intelligent diagnosis of chronic kidney disease

Yu Zengshan,Zhang Zhibin,Guo Shan,Li Zelong,Chen Hao,Gai Jichuan,Wei Jiyuan,Xu Shiqi,Wang Mingli,Shi Guochao

A combined “immunochromatographic surface-enhanced Raman scattering (SERS) sensor–deep learning” detection strategy is proposed. Specifically, we first prepared an immunochromatographic SERS sensor with excellent surface enhancement capability for the specific recognition of neutrophil gelatinase-associated lipocalin (NGAL) molecules in serum, significantly enhancing the detection sensitivity of the target molecule. Subsequently, we integrated deep learning algorithms to perform preprocessing, feature extraction, and pattern recognition analysis on complex SERS spectral signals, overcoming the limitations of traditional algorithms in handling high-dimensional nonlinear data. This approach enables rapid, sensitive, and highly specific detection of NGAL. The platform achieves a detection limit as low as 0.1059 ng/mL with a broad linear detection range. For clinical validation, serum samples from 14 volunteers were analyzed. Six deep learning models were employed to classify the acquired clinical spectral data, with the Residual Network (ResNet) model achieving a classification accuracy of 98.81%, a loss value of only 0.0877, and an area under the receiver operating characteristic curve (AUC) of 99.97%. In addition, in the analysis of new samples, the classification and prediction of data from patients and normal individuals were successfully achieved. The proposed “immunoassay surface-enhanced Raman scattering sensor - deep learning” combined detection strategy has demonstrated extraordinary potential in the rapid, sensitive and specific detection of NGAL, providing crucial technical support for the intelligent discrimination of chronic kidney disease. Graphical

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KOREAN JOURNAL OF CHEMICAL ENGINEERING · 2026 · IF 3.4

Preparation and Selective Adsorption Performance for Norfloxacin of Molecularly Imprinted Polymer Co-MOF/CNT@MIPs

Chen Jianjun,Wu Haowen,Ru Lei,Bai Hailong,Han Mingjie,Feng Hua,Men Jiying

In this work, surface molecularly imprinted polymers Co-MOF/CNT@MIPs were prepared based on metal-organic framework (MOF) and muti-walled carbon nanotubes (MWCNTs) as matrix, and norfloxacin (NOR) as template molecular. The structural characteristics of molecular imprinted polymer Co-MOF/CNT@MIP were confirmed by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM), thermogravimetric analysis (TGA), Brunauer–Emmett–Teller (BET), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS). The adsorption and selective recognition performances of Co-MOF/CNT@MIP for NOR were also investigated. The adsorption of Co-MOF/CNT@MIP for NOR reaches equilibrium at 300 min, and pseudo-second-order (PSO) model is more fit for adsorption kinetic. The adsorption capacity of Co-MOF/CNT@MIP for NOR reaches 78.6 mg/g with 1.5 mg/mL at 25℃ via the hydrogen bond interaction and “lock-key” imprinted cavities, and the D-R model is fit for adsorption isotherm. The adsorption amount decreases as increasing the temperature, which is an exothermic and spontaneous process. The imprinted polymer exhibits an excellent imprinted factor of 2.08 and high selective factor above 1.93, and it is satisfactory reusability for five cycles.

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JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE · 2026 · IF 2.6

Preparation and High-Temperature Tribological Properties of Na2O-CaO-P2O5 Phosphate Glass Coating

Lv Fanfan,Wang Wei,Wei Chunyan,Sun Zhuang,Gao Yuan,Wang Kuaishe

Glass lubricants are widely used in titanium alloy extrusion forming due to their excellent high-temperature stability. In this paper, twenty phosphate glass compositions with varying Na 2 O: CaO: P 2 O 5 ratios were designed. Through a series of experiments and analyses, the phosphate glass lubricant suitable for low-temperature titanium alloy extrusion was identified. When the Na 2 O: CaO: P 2 O 5 ratio in the glass lubricant was 3:2:5, the material exhibited the melting temperature of 850 °C and the glass transition temperature below 450 °C. Using methylcellulose (a readily vaporizable binder), the glass lubricant coating was prepared via the slurry method and sprayed at 130 °C. High-temperature tribological tests demonstrated outstanding anti-friction and wear-resistant properties at 750 and 800 °C, with average coefficients of friction of 0.2127 and 0.2112, respectively, and wear rates of 7.85 × 10 −5  mm 3 /N·m and 7.55 × 10 −5  mm 3 /N·m. The lubrication mechanism is attributed to the intrusion of Al 3+ and Ti 4+ ions from the oxide scale on the substrate surface into the phosphate glass. These ions react with the molten liquid, forming the reaction layer of NaAlP 2 O 7 and NaTi 2 (PO 4 ) 3 with three-dimensional open framework. The reaction layer interacts with the molten liquid to form the lubricating film with good elasticity, high density, and uniformity. Furthermore, the ion intrusion shortens the glass chain length, thereby enhancing the anti-friction and anti-wear properties of the glass lubrication coating.

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IONICS · 2014 ·Vol. 20 ·期 8 ·1055-1061 · IF 1.836

Influence of hydrophilic properties on capacitive behavior of functionalized graphene

Tian Hua,Wang Lin,Qin Xiujuan,Shao Guangjie

Super-hydrophobic graphene was treated with 4-benzenediazoniumsulfonate to obtain a series of functionalized graphene (FG) with enhanced hydrophilic properties. The results from Fourier transform infrared (FT-IR) spectra and thermogravimetric (TG) analyses demonstrate that −SO 3 H groups are covalently anchored to functionalized graphene and alter the thermal stability of graphene-based materials. In comparison to pristine graphene (PG), functionalized graphene as prepared exhibits enhanced hydrophilic properties which can be conducted by varying the diazotization-coupling reaction time. Cyclic voltammetry (CV) curves indicate that enhanced hydrophilic properties improve the capacitance of functionalized graphene up to twice than that of pristine graphene in Na 2 SO 4 electrolytes. Moreover, electrochemical impedance spectroscopy (EIS) reveals that the high level of functionalization will cause the decrease of the electric conductivity and capacitive performance, suggesting that functionalization of graphene provides the competitive relationship between the positive hydrophilicity increase and the negative conductivity decrease to capacitive performance.

研究领域: 材料科学 · 电化学 · 纳米技术 · 储能
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IONICS · 2021 ·Vol. 27 ·期 8 ·3663-3669 · IF 2.817

Hierarchical Fe/Fe3C/C nanofibers as anodes for high capacity and rate in lithium ion batteries

Xiang Tong,Chen Zhi,Rao Zhixin,Yan Mingge,Feng Zhijun,Li Xibao,Yang Huiyong,Huang Juntong,Shen Xing

Iron carbide (Fe 3 C) has gained significant attention for use in energy storage applications. Furthermore, using a nano-scale metal as the catalyst can reduce the formation of a solid electrolyte interface (SEI), thus enhancing capacity. For these reasons, hierarchical Fe/Fe 3 C/C nanofibers are prepared by electrospinning with subsequent thermal treatment and used as the anodes for lithium ion batteries (LIBs). These anodes demonstrate a good rate and high capacities. At 0.1 A g −1 , the Fe/Fe 3 C/C nanofiber electrode maintains 518 mA h g −1 after 100 cycles. When tested at 1 A g −1 , the discharge capacity gradually increases and reaches 663 mA h g −1 after 1200 cycles. This work demonstrates the possibility to design and develop transition metal carbides (TMCs) for use in energy storage.

研究领域: 材料科学 · 储能技术 · 纳米技术 · 电化学
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH · 2015 ·Vol. 22 ·期 13 ·9668-9675 · IF 2.828

Reducing the bioavailability of cadmium in contaminated soil by dithiocarbamate chitosan as a new remediation

Yin Zheng,Cao Jingjing,Li Zhen,Qiu Dong

Dithiocarbamate chitosan (DTC-CTS) was used as a new amendment for remediation of cadmium (Cd)-contaminated soils to reduce the Cd bioavailability. Arabidopsis thaliana was chosen as a model plant to evaluate its efficiency. It was found that DTC-CTS could effectively improve the growth of A. thaliana . The amount of Cd up-taken by A. thaliana could be decreased by as much as 50 % compared with that grown in untreated Cd-contaminated soil samples. The chlorophyll content and the aerial biomass of Arabidopsis also increased substantially and eventually returned to a level comparable to plants grown in non-contaminated soils, with the addition of DTC-CTS. These findings suggested that DTC-CTS amendment could be effective in immobilizing Cd and mitigating its accumulation in plants grown in Cd-contaminated soils, with potential application as an in situ remediation of Cd-polluted soils.

研究领域: 环境科学 · 土壤学 · 植物生理学 · 修复技术
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH · 2022 ·Vol. 29 ·期 49 ·74173-74184 · IF 5.19

Differential aggregation of polystyrene and titanium dioxide nanoparticles under various salinity conditions and against multiple proteins types

Avellán-Llaguno Ricardo David,Zhang Xu,Zhao Peiqiang,Velez Alberto,Cruz Marilyn,Kikuchi Jun,Dong Sijun,Huang Qiansheng

The interaction of nanoplastics (NPls) and engineered nanoparticles (ENPs) with organic matter and environmental pollutants is particularly important. Therefore, their behavior should be investigated under the different salinity conditions, mimicking rivers and coastal environments, to understand this phenomenon in those areas. In this work, we analyzed the elementary characteristics of polystyrene-PS (unmodified surface and modified with amino or carboxyl groups) and titanium dioxide-TiO2 nanoparticles. The effect of salinity on their colloidal properties was studied too. Also, the interaction with different types of proteins (bovine serum albumin-BSA and tilapia proteins), as well as the formation of the BSA corona and its effect on the colloidal stability of nanoparticles, were evaluated. The morphology and dispersion of sizes were more uniform in unmodified-surface PS-NPs (70.5 ± 13.7 nm) than in TiO2-NPs (131.2 ± 125.6 nm). Likewise, Rama spectroscopy allowed recognizing peaks associated with the PS phenyl group aromatic ring in unmodified-surface PS-NPs (621, 1002, 1582, and 1602 cm −1 ). For TiO2-NPs, the data suggest belonging to the tetragonal form, also known as rutile (445, 610 cm −1 ). The elevation of salinity dose-dependently decreased NP colloid stability, with more significant variation in the PS-NPs compared to TiO2-NPs. The organic matter is also involved in this phenomenon, differentially as a function of time compared to its absence (unmodified-surface PS-NPs 30 psu/TOC 5 mgL −1 /24 h: 2876.6 ± 378.03 nm; unmodified-surface PS-NPs 30 psu/24 h: 2133 ± 49.57 nm). In general, the TiO2-NPs demonstrated greater affinity with all proteins tested (0.066 g/L). It was observed that morphology, size, and surface chemical modification intervene in a relevant way in the interaction of the nanoparticles with bovine serum albumin (unmodified-surface PS-NPs 298 K: 6.08E +02 ; 310 K: 6.63E +02 ; TiO2-NPs 298 K: 8.76E +02 ; 310 K: 1.05E +03 L mol −1 ) and tilapia tissues proteins (from blood, gills, liver, and brain). Their morphology and size also determined the protein corona formation and the NPs’ agglomeration. These findings can provide references during knowledge transfer between NPls and ENPs.

研究领域: 环境纳米技术 · 胶体与界面科学 · 水环境化学 · 纳米毒理学 · 蛋白质-纳米颗粒相互作用
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CATALYSIS LETTERS · 2026 ·Vol. 156 ·期 6 ·161 · IF 2.5

The Key Role of Frustrated Lewis Pairs for Selective Hydrogenolysis of Furfuryl Alcohol

Zhang Jiawen,Liu Qiaoyun,Hu Yuanding,Zhao Danpu,Gao Yuanyuan,Liu Zhongyi,Sun Ailing

1,2-pentanediol(1,2-PeD), as a high-value-added fine chemical, is highly prone to be prepared by selective hydrogenolysis of furfuryl alcohol (FOL). However, the commonly used single reducible metal oxide or alkaline metal oxide carriers have poor interface controllability, limiting the selective cleavage of C–O bonds. To address this challenge, this paper innovatively designed a cerium-magnesium composite oxide and prepared Pt/CeMgO 2-x catalysts for the hydrogenolysis of FOL. The highest selectivity to 1,2-PeD reaching 69% at fully conversion was obtained. Characterizations confirmed that the cerium-magnesium solid solution structure formed by magnesium doping promotes the reduction of platinum species. Furthermore, the construction of frustrated Lewis pairs (FLPs) between Ce 3+ (Lewis acid sites) near oxygen vacancies and surface –OH groups (Lewis base sites) facilitated the selective cleavage of the C–O bond in the furan ring. This work provides a novel strategy for regulating C–O bond hydrogenolysis in heterogeneous catalysis via FLPs engineering, offering insights for valorizing biomass-derived compounds. Graphical The alternative text for this image may have been generated using AI.

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NEUROCHEMICAL RESEARCH · 2022 ·Vol. 48 ·期 5 ·1305-1319 · IF 4.414

Gelsemine Exerts Neuroprotective Effects on Neonatal Mice with Hypoxic-Ischemic Brain Injury by Suppressing Inflammation and Oxidative Stress via Nrf2/HO-1 Pathway

Cheng Shen,Chen Chen,Wang Liling

Given that the role of Gelsemine in neuroinflammation has been demonstrated, this research aimed to investigate the effect of Gelsemine on neonatal hypoxic-ischemic (HI) brain injury. An in vivo HI brain injury neonatal mouse model and an in vitro oxygen–glucose deprivation (OGD) cell model were established and pretreated with Gelsemine. The brain infarct volume, neuronal loss and apoptosis, as well as spatial learning and memory were examined by TTC staining, Nissl’s staining, TUNEL staining and Morris water maze test. Immunohistochemical staining was applied to detect the microglia cells and astrocytes in the mouse brain tissue. The cell viability was analyzed by CCK-8 assay. The levels of malondialdehyde (MDA), superoxide dismutase (SOD), TNF-α, IL-1β, and IL-6 were determined via ELISA. The lactate dehydrogenase (LDH) release and reactive oxygen species (ROS) level in OGD-treated cells were detected by colorimetry and DCFH-DA staining. Nrf2, HO-1, and inflammation-related factors were analyzed by immunofluorescence, qRT-PCR, or western blot. Gelsemine reduced the infarct volume and neuronal loss and apoptosis, yet improved spatial learning and memory impairment of HI-injured mice. Gelsemine inhibited the elevated MDA, TNF-α, IL-1β, IL-6, LDH and ROS levels, promoted the reduced SOD level and viability, and strengthened the up-regulation of HO-1 and Nrf2 in brain tissues and OGD-treated cells. However, Nrf2 silencing reversed the effects of Gelsemine on the Nrf2/HO-1 pathway, inflammation, and oxidative stress in OGD-treated cells. Gelsemine produces neuroprotective effects on neonatal mice with HI brain injury by suppressing inflammation and oxidative stress via Nrf2/HO-1 pathway.

CAS / MDL: 64-17-5
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CELLULOSE · 2022 ·Vol. 30 ·期 2 ·1225-1244 · IF 6.123

Low delay flexible paper-based electrode for capacitive sensor filled through carbon-based materials

Liu Huan,Quan Jingran,Wang Junyao,Hou Qi,Wang Rui,Cui Bowen,Lang Tianhong,Chen Yansong,Pan Hongxu,Xu Jianxin,Yang Hanbo,Li Lixiang,Liu Yahao

Paper-based sensors have good application prospects due to their flexibility and environmental protection. However, paper-based materials are difficult to balance both conductivity and flexibility. This paper mainly reports a high porosity conductive paper based on bamboo wood mixed fiber materials through the wet-manufacture method. The crucial material properties, and long-chain structure of PEDOT:PSS, play an important role in conductivity and flexibility. The relevant experiments show that conductive paper has excellent physical properties and electrical signal transmission capacity. Among them, the conductivity of paper-based electrodes is up to 18.52 S/cm, and there is a low delay in the transmission of the electric signal, when the signal frequency is 300 kHz, the phase frequency angle changes by only 4.9°, not only that, as an electrode, the human pulse signal measured in the capacitive sensor is normal. Under the action of other composite materials, the manufactured electronic paper has a certain mechanical strength, and the thickness is about 90 μm, lower than ordinary paper products. The research shows that the paper-based electrode has the advantages of high conductivity, low hysteresis, light, and thinness, which provides the possibility to be used as a flexible electrode. Graphical abstract

CAS / MDL: 9004-34-6
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CHROMATOGRAPHIA · 2022 ·Vol. 86 ·期 1 ·97-105 · IF 2.213

Exploration of the Simple and Green Synthetic Route of Hollow Titanium Dioxide Microspheres for In-Depth Analysis of Phosphopeptides in the Serum of Nasopharyngeal Carcinoma Patients

Wang Baichun,Du Jianglong,Liu Bin,Xu Qian,Huang Jingli,Liu Chunbo,Yan Yinghua,Ding Chuan-Fan

Nasopharyngeal carcinoma (NPC), as a malignant tumor, has increasingly affected the health and survival of human, and certain changes in the phosphorylation level of protein have been found in the serum of NPC patients. Thus, the investigation of phosphoproteins/phosphopeptides in human serum of NPC patient will conduce the understanding of the related pathogenesis and pathological processes. However, there are certain limitations in the direct detection of phosphoprotein/phosphopeptide in patient serum by mass spectrometry. Here, we designed a simple and green synthetic route to prepare hollow TiO 2 spheres for phosphopeptide pre-treatment using the hard template method with carbonaceous spheres as the template, providing a novel path for the exploration of hollow spheres and even functionalized probes. The TiO 2 spheres with unique hollow structure exhibit a low detection limit (0.2 fmol), high loading capacity (250 mg/g), stable reusability (ten cycles), high selectivity (1:1500), and relatively good recovery rate (80.3%). Besides, hollow TiO 2 spheres identify 25 phosphopeptides with 19 phosphorylation sites corresponding to 18 phosphoproteins and 15 phosphopeptides with 14 phosphorylation sites corresponding to 10 phosphoproteins from the serum of the healthy person and NPC patient, respectively. Among them, four phosphopeptides with five phosphorylation sites are only detected in NPC samples. After gene ontology analysis of cell components and molecular functions, it is discovered that the identified phosphoproteins are inseparable from NPC related events, including heparin binding, lipid binding, endoplasmic reticulum cavity, and early endosomes, signaling that related functional pathways may be involved in the pathological process of NPC in some way.

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