Journal of Cleaner Production
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2023
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IF 11.1
Yaopeng Zhang,Miaojia Du,Hui Chen,Chensi Shen,Mengmeng Lou,Chenye Xu,Chunyan Ma,Fang Li
Adsorption enrichment coupled with oxidative degradation is a promising technique for eliminating tetracycline (TC) from an aqueous environment . However, the high cost associated with this technique limits its applicability. Thus, in this study, we synthesized Cu 2 O and CuFe 2 O 4 bimetallic-modified chitosan particles (Cu(I)–CuFe 2 O 4 @CS) with high adsorption efficiency and self-cleaning performance. The self-cleaning performance was driven by the in-situ generated reactive oxygen species (ROS). Batch experiments and characterization methods indicated that 97.39% of TC was rapidly adsorbed on the particles surface and subsequently degraded by in-situ generated ROS, to achieve a self-cleaning process. The Cu(I)–CuFe 2 O 4 @CS/TC system exhibited maximum O 2 • - and H 2 O 2 concentration of 12.95 μmol/L and 42.05 μmol/L, respectively. Cu 2 O was the main source of the ROS generation, while CuFe 2 O 4 effectively adsorbed TC and contributed to the synergistic accumulation of ROS. Moreover, the adsorbed TC with reductive functional properties facilitated the reduction of Fe(III)/Fe(II) and Cu(II)/Cu(I) cycles, thereby improving TC elimination efficiency.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Rong Chang,Donghui Zhao,Chen Zhang,Kaiyue Liu,Yuanmeng He,Fangxia Guan,Minghao Yao
Melanoma excision surgery is usually accompanied by neoplasm residual, tissue defect, and bacterial infection, resulting in high tumor recurrence and chronic wound. Nanocomposite hydrogels can satisfy the twin requirements of avoiding tumor recurrence and skin wound healing following skin melanoma surgery due to their photothermal anti-tumor and anti-bacterial activities. In this study, carboxymethyl chitosan, oxidized fucoidan and polyphenol–metal nanoparticle (PMN) of tannic acid capped gold nanoparticles were used to fabricate multifunctional nanocomposite hydrogels through Schiff base reaction. The prepared hydrogel demonstrated outstanding photothermal effect, and the controlled high temperature will rapidly kill melanoma cells as well as bacteria within 10 min. Good injectability, self-healing and adhesion combined with high reactive oxygen species (ROS) scavenging capacity, hemostasis and biocompatibility made this hydrogel platform perfect for the postoperative treatment of melanoma and promoting wound healing. With the assistance of NIR irradiance, hydrogel can inhibit tumor tissue proliferation and promote tumor cell apoptosis, thereby helping to prevent melanoma recurrence after surgical removal of tumors. Simultaneously, the irradiance heat and polyphenol component kill bacteria on the wound surface, eliminate ROS, inhibit inflammatory responses, and promote angiogenesis, collagen deposition, and skin regeneration, all of which help to speed up wound healing.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Jian Wu,Jinzhe Chang,Jun Liu,Jiajian Huang,Zixia Song,Xiaofeng Xie,Liting Wei,Jiaxin Xu,Suqing Huang,Dongmei Cheng,Youzhi Li,Hanhong Xu,Zhixiang Zhang
A chitosan-based nanoparticle was prepared using chitosan (CS) and O -carboxymethyl chitosan ( O -CMCS). Our study revealed that chitosan/ O -carboxymethyl chitosan/tebuconazole nanoparticles (CS/ O -CMCS/TBA NPs) exhibited superior antifungal activity, foliar adhesion, and microbial target adhesion performance compared to commercial suspension concentrate (SC). The antifungal activity of CS/ O -CMCS/TBA NPs against C. gloeosporioides , with a 3.13-fold increase in efficacy over TBA (SC). We also found that low concentrations of CS/ O -CMCS NPs promoted the growth of C. gloeosporioides and enhanced the fungal catabolism of chitosan. Overall, the CS/ O -CMCS/TBA NPs were found to possess the remarkable capability to selectively aggregate around pathogenic microorganisms and CS/ O -CMCS NPs can enhance the fungal catabolism of chitosan. CS/ O -CMCS/TBA NPs, as a “sugar-coated bomb”, was a promising asset for effective plant disease management and pesticide utilization through the affinity of chitosan-based nanoparticles and C. gloeosporioides , enabling targeted delivery and targeted release of their encapsulated active ingredient, which was important for the development and application of biocompatible chitosan-based nanopesticides.
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E-POLYMERS
·
2023
·Vol. 23
·期 1
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IF 3.7
Xiaoyu Jie,Bing-Chiuan Shiu,Huazhong Wu,Yuchi Zhang,Yuansong Ye,Chunxiang Lin,Run Fang
Chitosan (CS) is widely used in the treatment of wastewater containing metal ions. However, the poor stability in acidic aqueous solutions severely limits its application in many practical scenarios. In this work, a CS-based composite nanofiber membrane was prepared by electrospinning using urushiol, a natural biomaterial, as the cross-linking agent. The application of the CS-urushiol (CS-U) membrane in the adsorption and recovery of Cr( vi ) in wastewater was systematically studied. The CS-U membrane showed great resistance to strongly acidic and oxidative environments, and the adsorption process combined two mechanisms of electrostatic attraction and redox reaction. Due to the nanoscale fibers, porous structure, and strong acid resistance, the CS-U membrane adsorbed Cr( vi ) rapidly and efficiently in both batch and continuous modes. Moreover, the adsorption capacity and selectivity of the CS-U membrane for Cr( vi ) could be maximized simultaneously by adjusting the solution pH, promoting the recovery of high-purity Cr 2 O 3 .
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ACS Applied Materials & Interfaces
·
2023
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IF 9.5
Jinghua Yu,Qingqing Zhu,Wenli Ma,Yajie Dai,Shuhuan Zhang,Fanghui Wang,Hong Zhu
The present paper studied the chitosan-doped composite diaphragm by the phase exchange method with the objective of developing a composite diaphragm that complies with the alkaline water electrolysis requirements, as well as tested the electrolytic performance of the diaphragm in alkaline water electrolysis. The structure and morphology are characterized by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). The performance of chitosan-doped composite diaphragms was tested; CS3Z12 composite diaphragm with a low area resistance (0.20 Ω cm2), a high bubble point pressure (2.75 bar), and excellent electrochemical performance (current density of 650 mA cm–2 at 1.83 V) shows the best performance. Moreover, the performance of the synthesized composite diaphragm is significantly elevated compared to commercial diaphragms (Zirfon PERL), which is promising for practical application in alkaline electrolytic cells.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2021
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IF 6.953
Yingbi Chen,Jiali Tang,Shixing Wang,Libo Zhang
A chitosan-based adsorbents (CS-Ninhydrin) was prepared by grafting ninhydrin for Pb(II) ions adsorption. SEM-EDS, XRD and FTIR analysis were used to characterize the synthesized CS-Ninhydrin. The static adsorption experiments showed that CS-Ninhydrin had a good removal rate for Pb(II) ions in a wide range of pH 3 to 7, quickly reached equilibrium (120 min) and had a higher adsorption capacity (196 mg/g). Pseudo second-order and Langmuir models showed that the adsorption process of Pb(II) by CS-Ninhydrin was a single-layer chemical adsorption. Temperature experiments showed that the reaction was a spontaneous exothermic process. In the wastewater experiment, CS-Ninhydrin showed an excellent selectivity to Pb(II) ions. The reusability of CS-Ninhydrin was perfect after five adsorption-desorption cycles. The main adsorption mechanism was the chelating and electrostatic action between N and O groups in CS-Ninhydrin and Pb(II) ions. Therefore, the new adsorbent CS-Ninhydrin was expected to promote the wide application of chitosan in Pb(II) adsorption.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2021
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IF 4.539
Xia Chen,David H. Bremner,Yuhan Ye,Jiadong Lou,Shiwei Niu,Li-Min Zhu
The premature leakage of chemotherapeutics during delivery impedes drugs from entering tumor cells, which produces considerable side effects in normal organs. Herein, we describe a hydrophobic-hydrophilic balanced self-assembled prodrug nanoparticle ( [email protected] ), formed via a facile synthesis based on chitosan oligosaccharide to reduce the non-targeting risk of premature leakage of chemotherapeutics during their delivery. The [email protected] have a suitable size (~186 nm) with a doxorubicin (DOX) loading of 9.88% and an oleanolic acid (OA) loading efficiency of 27.34%. The release of DOX or OA is pH-dependent and responds particularly well to the acidic tumor microenvironment. In vitro antitumor activity studies revealed that [email protected] had enhanced performance in promoting tumor apoptosis and displayed significant anticancer effects compared to mono-delivery. In vitro cell studies showed that HA-functionalized nanoparticles could enhance the cellular uptake in tumor cells. Therefore, [email protected] is a promising vehicle for CD44-targeted co-delivery of cancer chemotherapy, which deserves further evaluation.
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Materials Today Communications
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2021
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IF 3.383
Ruizhe Lian,Jinxing Cao,Xiaohong Jiang,Aleksandr V. Rogachev
Zinc oxide nanoparticles (ZnO-NPs) with attractive antibacterial properties have been widely used in the field of antimicrobial films. In this study, ZnO-NPs, corn-starch (ST), chitosan (CS) as materials and glycerol as plasticizer . To avoid the pungent smell of acetic acid, l -malic acid was used to prepare chitosan solution. The effect of ZnO-NPs incorporated CS/ST films on physicochemical properties, antimicrobial activity and cytocompatibility were investigated. The results showed that the composite films with 6%(w/w) ZnO-NPs, the mass ratio of CS/ST was 1:1, whose TS value reached 19.64 ± 0.75 MPa, possessed the best physicochemical properties comparing to the composite films without ZnO-NPs. Furthermore, the inhibition zone diameters of the composite films with ZnO-NPs against Staphylococcus aureus were 29.36 ± 2.40 mm, 24.90 ± 0.40 mm and 22.00 ± 0.34 mm respectively after 0, 7 and 14 days of sustained release, which was higher than the inhibition zone diameters of the composite films without ZnO-NPs ( p < 0.05). Moreover, cell viability of MC3T3-E1 cells on the surface of the composite films with ZnO-NPs was still 95.63±3.17 % ( p < 0.05), showing excellent cytocompatibility. The overall results of this study pointed out that the CS/ST/ZnO-NPs films have potential application in food packaging industry and medical device packaging industry.
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LANGMUIR
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2021
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IF 3.882
Yingying Chai,Yuefei Wang,Bingqi Li,Wei Qi,Rongxin Su,Zhimin He
In this work, lignin/chitosan nanoparticles (Lig/Chi NPs) with controlled structures were synthesized in a simple and scalable microfluidic system. When the positively charged chitosan and the negatively charged lignin solution were blended in a microreactor, Lig/Chi NPs were rapidly formed via the electrostatic coassembly between the amino groups of chitosan and the carboxyl groups of lignin. The ζ potential changes from negative (−13 mV) to positive (+54.5 mV) for Lig NPs and Lig/Chi NPs, respectively. The scanning electron microscopy (SEM) and transmission electron microscopy (TEM) results demonstrated that Lig/Chi NPs have an average particle size of about 180 nm, which can be used as nanocarriers for drug delivery. The anticancer drug nanoparticles with docetaxel (DTX) and curcumin (CCM) were prepared by coassembly with Lig/Chi NPs in a microreactor, which had good drug loading efficiency, biocompatibility, and can release drugs in response to pH in the weakly acidic environment of the tumor. The drug release amounts in acidic solutions that simulated the tumor microenvironment were 51% (DTX@Lig/Chi NPs) and 50% (CCM@Lig/Chi NPs), respectively, which were better than the release amounts at pH 7.4, and have an obvious killing effect on HeLa cells.
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DENTAL MATERIALS JOURNAL
·
2021
·Vol. 40
·期 2
·422-430
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IF 2.102
Ju NIU,Di LI,Zeying ZHOU,Jingyue ZHANG,Dandan LIU,Wendi ZHAO,Chengji ZHAO,Xiaoqiu LIU
This study evaluated the effect of incorporating phosphorylated chitosan/amorphous calcium phosphate nanocomplex (Pchi/ACP) into an experimental light-cure composite resin on mechanical-chemical properties and human dentin remineralization. The results showed that the mechanical strength and contact angles of the resins decreased with the increase incorporation of Pchi/ACP. Release concentrations of calcium in saline solution were measured at different time points, showing the incorporation of Pchi/ACP significantly increased calcium release within 14 days, and kept steady thereafter. Finally, the demineralized dentin slabs treated with our resins for four weeks were characterized by SEM-EDS. Various amounts of apatite were formed on the dentin slabs which were treated with the resins containing Pchi/ACP, whereas no apatite was formed without Pchi/ACP. In conclusion, the Pchi/ACP-incorporating composite resin can be a promising dental material due to its favorable mechanical and remineralization properties.
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CARBOHYDRATE POLYMERS
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2021
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IF 9.381
Fang Wang,Jiarui Li,Cheng Chen,Hong Qi,Kexin Huang,Sheng Hu
Chemo-photothermal combination therapy has great promise for enhanced tumor treatment. Hereby, we developed a complex nanoparticle using electrostatic absorption method, in which the inner chitosan (CS) NPs loaded polypyrrole (PPy) nanoparticles and 5-fluorouracil (5Fu), the outer shell was carboxymethyl cellulose (CMC) crosslinked with disulfide . The drug loaded polysaccharide complex nanoparticles displayed good photothermal effects, and the drug release would be triggered by multi-model response of NIR irradiation, high glutathione (GSH) and weak acidity in tumor environment. In vitro biological studies indicated the nanopartiles could be effectively internalized by HepG2 cancer cells. Moreover, the remarkable inhibition of the CMC complex PPy and 5Fu loaded CS nanoparticles (CMC/ [email protected] + 5Fu NPs) against tumor growth was achieved in HepG2-bearing mice model, suggesting its great potential for synergetic chemo-photothermal therapy.
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INDUSTRIAL CROPS AND PRODUCTS
·
2021
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IF 5.645
Yu Peng,Hui Huang,Yilan Wu,Shuanghui Jia,Fang Wang,Jun Ma,Yang Liao,Hui Mao
Bayberry tannin (BT), a typical plant tannin, was grafted onto chitosan microfibers (CF) through the Mannich reaction to synthesize biosorbent (BT-CF) that was effective for adsorptive removal of Pb 2+ from aqueous solutions. The adsorption capacity of Pb 2+ on the BT-CF was pH-dependent, which increased from 4.5 mg/g to 21.7 mg/g along with increasing solution pH from 2.5−5.5. The adsorption capacity increased with the increase of temperature from 303 K to 323 K, and thermodynamic calculations indicated that the adsorption of Pb 2+ on the BT-CF was an endothermic process. The adsorption isotherms were well described by the Langmuir isotherm model with correlating constant (R 2 ) higher than 0.980. The adsorption kinetics were well described by the pseudo-second-order rate model. The Pb 2+ adsorbed on the BT-CF was desorbed using diluted acid solution. Column adsorption experimental results confirmed that the BT-CF was applicable for continues adsorptive removal of Pb 2+ at the low concentration of 2.0 mg/L.
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