GREEN CHEMISTRY
·
2017
·Vol. 19
·期 16
·3869-3879
·
IF 9.125
Shurong Wang,Yuan Zhao,Haizhou Lin,Jingping Chen,Lingjun Zhu,Zhongyang Luo
For the purpose of building a green reaction system to produce furfural (FF), the conversion of two important pentoses from hemicellulose, namely xylose and arabinose, was investigated in an aqueous reaction system including a Lewis acidic ionic liquid as a catalyst and renewable γ-valerolactone (GVL) as a co-solvent. The results showed that the introduction of GVL greatly improved the reactivity of pentose and inhibited the secondary decomposition reaction of FF compared to a pure-water reaction system. NMR analysis suggested that the composition of pentose conformers was greatly altered towards a reactive distribution. The highest FF yields were 79.76% (from xylose) and 58.70% (from arabinose), which were obtained at 140 °C. The influence of reaction parameters on pentose conversion was also studied. A comparison between different reaction conditions suggested that arabinose had less reactivity than xylose, leading to its lower conversion rate and FF yield. Furthermore, xylan and real biomass materials were tested in the proposed reaction system, and decent FF yields of up to 69.66% (from xylan) and 47.96% (from corn stalk) were obtained.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2014
·Vol. 15
·期 4
·6897-6909
·
IF 2.339
Huanan Hu,Fangli Qiu,Anguo Ying,Jianguo Yang,Haiping Meng
A mild, efficient, and environmentally benign protocol for the synthesis of tetrahydrobenzo[b]pyran derivatives in the presence of readily accessible, biodegradable, and choline hydroxide based ionic liquid as catalyst has been established. The key features of the reported methodology include good to excellent yields of desired products, simple work-up procedure and good recyclability of catalysts, which may be a practical alternative to the existing conventional processes for the preparation of 4-Hpyrans to cater to the requirements of academia as well as industry.Keywords:pyran;choline hydroxide;ionic liquid;cost-effectiveness;biodegradability;recyclability
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ANALYTICAL CHEMISTRY
·
2014
·
IF 5.825
Rui Li,Kangbing Wu,Changxian Liu,Yin Huang,Yanying Wang,Huaifang Fang,Huijuan Zhang,Chunya Li
A novel ionic liquid, 4-amino-1-(3-mercapto-propyl)-pyridine hexafluorophosphate (AMPPH), was successfully synthesized and characterized. Subsequently, AMPPH was used as a functional monomer to fabricate AMPPH-modified gold nanoparticles (AMPPH–AuNPs) via a one-pot synthesis method. The as-prepared AMPPH–AuNPs were confirmed with transmission electron microscopy and X-ray photoelectron spectroscopy. AMPPH–AuNPs were used to construct a biocompatible interface to immobilize rabbit anti-human IgG (anti-HIgG) onto a glassy carbon electrode (GCE) surface, followed by a cross-linking step with glutaraldehyde to fabricate an anti-HIgG–AMPPH–AuNPs/GCE. The nonspecific binding sites were enclosed with bovine serum albumin (BSA) to develop an immunosensor for human IgG. Electrochemical impedance spectroscopy, cyclic voltammetry and differential pulse voltammetry were used to investigate the electrochemical properties of the developed immunosensor. The results indicate that AMPPH–AuNPs can improve the immunosensing performance. The current response of the immunosensor was found linearly related to human IgG concentration in the range of 0.1–5.0 ng mL–1 and 5.0–100.0 ng mL–1. The detection limit is estimated to be 0.08 ng mL–1 (S/N = 3). The obtained immunosensor was successfully applied to the analysis human IgG immunoglobulin in human serum, and the results were well consistent with ELISA method.
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ELECTROCHIMICA ACTA
·
2017
·
IF 4.798
Yanqing Wang,Zengqi Zhang,Masaki Haibara,Deye Sun,Xiaodi Ma,Yongcheng Jin,Hirokazu Munakata,Kiyoshi Kanamura
In this research, we demonstrate a new method for reducing the shuttle effect by confining polysulfide in separator area through the use of polyimide (PI) separator with reversible adsorption functions in lithium-sulfur batteries. As a comparison, the cells with polypropylene (PP) separators which have no function to adsorb dissoluble polysulfide show a result that the content of sulfur on lithium anode surface is increased up to 63.94% after 100th cycles with the content of N-methyl-N-butylpiperidinium bis-(trifluoromethylsulfonyl) imide (PP 14 TFSI) in the mixture electrolyte increasing. This result illustrates that the migration and reaction between dissolved polysulfide in PP 14 TFSI and lithium cannot be neglected although the solubility of polysulfide is slight in PP 14 TFSI solvent. However, when PI separators are introduced, besides improving the wettability with PP 14 TFSI-based electrolytes, experimental results also show that the PI separator has a reversible adsorption function to dissoluble polysulfide which is used to confining polysulfide in separator area to a certain extent due to the abundant nitrogen-, oxygen-containing functional groups in PI skeleton. What’s more, PI separator can decreases the sulfur content on lithium surface after cycling to 17.92% which decreases greatly than that with PP separator and improves its electrochemical performance.
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PHARMACEUTICAL RESEARCH
·
2022
·Vol. 39
·期 10
·2459-2474
·
IF 4.58
Hong Minghuang,Wang Qinglin,Wang Kai,Li Jinghui,Qi Ming-Hui,Ren Guo-Bin
Purpose The purpose of the present study was to explore the feasibility of transdermal delivery of metformin, a commonly used oral antidiabetic drug, by ionic liquid (IL) technology. Methods Metformin hydrochloride (MetHCl) was first transformed into three kinds of ILs with different counterions. The physicochemical properties of the obtained ILs were characterized in depth. The simulation of stable configuration and calculation of interaction energies were conducted based on density functional theory (DFT). Skin-PAMPA was used to evaluate the intrinsic transdermal permeation properties. The cytotoxicity assay of these ILs was conducted using HaCaT cells to evaluate the toxicity to skin. These metformin ILs were then formulated into transdermal patch, and the transdermal potential was further evaluated using in vitro dissolution test and skin permeation assay. Finally, the pharmacokinetic profiles of these metformin IL-containing patches were determined. Results Among all the three Met ILs, metformin dihexyl sulfosuccinate (MetDH) with proper overall physiochemical and biological properties demonstrated the highest relative bioavailability. Metformin docusate (MetD) with the highest lipophilicity and intrinsic transdermal permeability exhibited the most significant sustained release profile in vivo . Both MetDH and MetD were the promising candidates for further clinical investigations. Conclusions Overall, the properties of ILs were closely related to the structures of counterion. IL technology provided the opportunities to finely tune the solid-state and biological properties of Metformin and facilitated the successful delivery by transdermal route.
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BIOSENSORS & BIOELECTRONICS
·
2019
·
IF 9.518
Qiwen Peng,Xueyan Yan,Xinran Shi,Shanshan Ou,Hui Gu,Xiaoxing Yin,Guoyue Shi,Yanyan Yu
The superoxide anion (O 2 •− ) is an important reactive oxygen species (ROS) in the brain system, which has been associated with the development of many neurological diseases, including Alzheimer's disease (AD). Herein, we introduced a carbon fiber microelectrode (CFME) based in vivo technique for specific and sensitive monitoring of the O 2 •− radical in the living brains of both normal and AD model rats. Compared with other reported superoxide dismutase (SOD) electrochemical biosensors , the microsensor presented in our work was featured in the coating of a functionalized ionic liquid polymer (PIL) onto PB nanoparticles (PBNPs) and carbon nanotubes (CNT). It was demonstrated that the cationic and carboxyl-rich PILs provided abundant interaction sites with SOD to prevent enzyme leakage from sensor, which was beneficial for the enhancement of sensitivity. Additionally, CCK-8 assay and autoxidation of pyrogallol tests showed that MCF-7 cells maintained a high viability after incubated with PIL and most of the SOD bioactivity was retained in the presence of PIL, which implied the PIL itself possessed an excellent biocompatibility. These properties allow the sensor to track the fluctuation of O 2 •− levels in vivo between normal and AD rats. This is the first report on application of functionalized PIL to reveal the O 2 •− related pathological process of AD.
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CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Dewei Wang,Yatong Wang,Haiwei Liu,Wen Xu,Lang Xu
The exploration of various porous nanocarbon materials with an extraordinary electrochemical capacitive performance in ionic liquid (IL) electrolytes is urgently needed for development of the next-generation energy storage devices. Significant improvements in energy density have been achieved, however, supercapacitors with IL electrolytes usually suffer from issues related to low power density and large IR drop. Herein, we report an unprecedented carbon nanomesh that is made up of interconnected densely-packed carbon nanocages with ultrathin partially graphitic shells. The large specific surface area and well-developed mesopores combined with its unique structural features, make it a very competitive material for high-performance supercapacitor in IL electrolyte. Notably, this unique nanosheets morphology with lots of in-plane nanopores on their surface can provide fast cross-plane ion diffusion pathways, and meanwhile, the carbon nanocages with partially graphitic shells ensure the rapid electron transfer. The supercapacitor assembled with the optimized sample can deliver a high specific capacitance (up to 194 F/g at 1 A/g), superior rate capability (68% capacitance retention at 70 A/g), low IR drop (0.685 V at 70 A/g). Moreover, benefiting from the wide working voltage and high-rate capability, the energy densities can maintain at 56.1 Wh/kg even at an ultrahigh power density of 61.250 kW/kg. Strikingly, the as-assembled supercapacitor can successfully power a light-emitting diodes (LED, 2.2 V) module with 53 red LED lights demonstrating its great potential for practical applications in energy storage devices.
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JOURNAL OF CHROMATOGRAPHY A
·
2019
·
IF 3.858
Luwei Fang,Minglei Tian,Xuemin Yan,Wei Xiao,Kyung Ho Row
A convenient, and efficient multi-phase extraction method was used to isolate aristolochic acid from real samples. To increase the efficiency, a new dual ionic liquid-immobilized silica was used as a sorbent and the effects of the adsorption conditions were investigated. IM-BIM@Sil in a methanol/water (60:40, v/v) solution at 60 °C extracted the highest amount of aristolochic acid (16.69 mg/g) compared to the other sorbents examined. The sorbent was then applied to the multi-phase extraction of aristolochic acid. After extraction eight times, 2.4–70.9 × 10 −3 mg/g of aristolochic acid was isolated from nine real samples after several washing and elution steps. The recoveries of aristolochic acid ranged from 70.0% to 110.6% with relative standard deviations of 3.5%–9.1%, highlighting the accuracy of this method.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Peipei Gao,Wei Wang,Tao Tang,Rongge Hu,Mengyun Liu,Hanjie Wen,Ziyuan Zhou,Zhiqi Liu
The rapid expansion in the demand for LiFePO 4 (LFP) batteries has created a pressing need for recycling waste LFP batteries. However, the direct extraction of lithium from their acid leachate remains a significant challenge. This study developed a novel extraction system using tributyl phosphate (TBP) as extractant and ionic liquids (ILs) as co-extractant for selective recovery of Li + from H 2 SO 4 leachate of waste LFP cathode. The single-factor experiment results demonstrated that TBP-[C 4 mim][NTF 2 ] (1-butyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]imide) exhibited higher lithium extraction efficiency under acidic conditions compared to TBP-[C 4 mim][PF 6 ] (1-Butyl-3-methylimidazolium hexafluorophosphate). Moreover, a four-stage cross-current extraction process utilizing the TBP-[C 4 mim][NTF 2 ] system was demonstrated to efficiently and selectively extract lithium from a real H 2 SO 4 leachate, achieving extraction efficiency and separation factor of 92.39% and 197.95, respectively. Mechanism insights from Fourier transform infrared spectroscopy (FT-IR) and theoretical calculations indicate that cationic exchange and a synergistic effect between TBP and IL enhance the selective extraction of lithium. The cation of IL (C 4 mim + ) enters aqueous phase, and Li + are extracted into organic phase in the form of Li + -TBP-[NTF 2 ] - with a larger binding energy. Furthermore, five cycles of extraction and stripping experiments not only yielded a lithium-enriched solution but also demonstrated the excellent stability of the TBP-[C 4 mim][NTF 2 ]. Finally, the Li + was ultimately recovered as high-purity Li 3 PO 4 via the chemical precipitation method. This study provides theoretical and technical references for efficient extraction of lithium from LFP acid leachate, which is crucial for comprehensive utilization of waste LFP cathodes.
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Russian Journal of Physical Chemistry A
·
2014
·Vol. 88
·期 8
·1317-1322
·
IF 0.488
Chen Guochang,Ye Mingfu,Qiao Hongbin,Qiu Xiaoning
An aryl alkyl ionic liquids with a tertiary amino group (N(CH 3 ) 2 ) in the cation were synthesized. As a ligand, the synthesized ionic liquids can coordinate with palladium to form N -heterocyclic carbene (NHC)-Pd complex which exhibited high efficiency in catalyzing Suzuki-Miyaura coupling reaction.
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ACS Applied Polymer Materials
·
2022
·
IF 4.855
Yanqing Qu,Yuxin Zha,Xiaoyu Du,Shuangping Xu,Mingyu Zhang,Liang Xu,Hongge Jia
Covalent organic frameworks (COFs) are a promising candidate for advanced water treatment membranes due to their numerous benefits, such as adjustable pore diameters, high crystallinity, chemical stability, and a well-organized channel structure. Liquid–liquid interfacial polymerization is an effective method for COF membrane synthesis owing to its comparatively milder reaction conditions and efficient collection of products from the reaction system. However, the fabrication of continuous COF membranes at a non-alkane/water interface remains a formidable task due to membrane flaws caused by solvent evaporation and the restriction of water-soluble monomers. At the alkane/ionic liquid interface, we synthesized two self-standing, flexible, imine-linked COF membranes with different thicknesses and morphologies. The ionic liquid as a solvent can dissolve various amines, and polyamide nanofilms can be formed by the intermolecular reaction between amines and trimesoyl chloride. The freestanding ultrathin selective membrane is created with continuous, defect-free, and vast areas of up to 2 cm in diameter wafer-scale pore sizes as ultrafast molecular sieving. The membrane exhibited an extremely high water flow of 67.37 L m–2 h–1 bar–1 as well as an excellent rejection (98.7% for methylene blue). The resulting polyamide nanofilms displayed ultrahigh water permeability and good dye rejection selectivity.
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Polymers
·
2020
·Vol. 12
·期 2
·292
·
IF 3.426
Yuan Tian,Xilan Feng,Yuping Zhang,Quan Yu,Xiaohao Wang,Mengkui Tian
Ionic liquids found a wide application in catalysis and extraction due to their unique properties. Herein, ethylene glycol dimethacrylate as the cross-linker and 1-vinyl-3- butylimidazolium tetrafluoroborate as functional monomer via thermally initiated free-radical polymerization was prepared as a novel copolymer solid phase micro-extraction (SPME) coating. A surface modified stainless-steel wire was implemented as the substrate. Factors affecting the extraction performances of the copolymer, including the molar ratio of monomers to cross-linkers, the amount of porogen agent, and polymerization time were evaluated and optimized. To evaluate the extraction performance, five commonly seen polycyclic aromatic hydrocarbons (PAHs) were taken as the analytical targets. The potential factors affecting extraction efficiency were optimized. The as-prepared SPME device, coupled with gas chromatography, was successfully applied for the determination of PAHs in water samples. The wide linear range, low detection limit, good reproducibility, selectivity, and excellent thermal stability indicate the promising application of the newly developed SPME fiber in environmental monitoring as well as in other samples having complex matrices.Keywords:solid phase micro-extraction;polyionic liquids;cross-linker;in-mold coating;polycyclic aromatic hydrocarbons;river water
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