SENSORS AND ACTUATORS B-CHEMICAL
·
2024
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IF 8
Zhidong Jin,Jinbo Zhao,Lin Liu,Fei Liu,Dewen Zhao,Zhou Wang,Fenglong Wang,Jiurong Liu,Yue Mou,Lili Wu
Realizing nitrogen dioxide (NO 2 ) detections based on semiconductor-based gas sensors with high tolerance to humidity conditions is deemed to be a long-term challenge. To independently acknowledge the physiosorbed-water influence mechanism on semiconductor-based sensors, hydrophobic zeolitic imidazolate framework-8 (ZIF-8) covered chemisorbed-oxygen-nonexistence zinc hydroxyfluoride (ZnOHF) snowflake-like nanorod bundles are synthesized for NO 2 detections with non-hindrance of interfering gases and high humidity in our work. Gas-sensing testing results display that the 0.6ZIF-8/ZnOHF-based gas sensor provides an optimum NO 2 response of 12.1–10 ppm NO 2 at the operating temperature of 200 ℃ with excellent NO 2 selectivity. As the relative humidity (RH) increases from 20% RH to 80% RH, the response of the 0.6ZIF-8/ZnOHF sensor shows a marginal fluctuation of only 13%, exhibiting outstanding anti-humidity characteristics towards NO 2 detections, the outperformed NO 2 selectivity and humidity tolerance of which are greatly attributed to the unique band structures of ZnOHF and the surficial hydrophobic treatment by ZIF-8, which is further validated via In-situ diffuse reflection infrared Fourier transform spectroscopy ( In-situ DRIFTS) and electronic structure analyses. Humidity impact on ZnOHF poses a persuasive evidence for establishing the separate physiosorbed water interfering mechanism on semiconductors. This work endows a perspective on optimizing humidity tolerance for semiconductor-based sensors at low operating temperature.
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CHEMICAL ENGINEERING JOURNAL
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2024
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IF 13.3
Tiantian Min,Jin Yue,Chuanxiang Cheng,Xiaoyun Ma,Shihan Weng,Yuwan Luo,Yujie Lei,Yangyang Long
Developing stimuli-responsive on-demand release systems is very important to effectively suppress microbial infections and excessive food decomposition. However, the commonly designed controlled release systems with a single responsiveness cannot accurately response to environmental changes in food packaging scenarios. Herein, a pH/enzyme dual-responsive active packaging was fabricated based on in situ growth of ZIF-8 nanoparticles (ZIF-8 NPs) on TEMPO-oxidized cellulose (TOCNF) film and loading with carvacrol (CAR), after that electrostatic adsorbing pectin as “gatekeeper” for fruit preservation. The developed CAR@ZIF-8/TOCNF/Pec film was able to respond to acidic condition and pectinase produced by microorganisms in the case of fungal infections during food storage, thus possessing a dual-responsive controlled-release function. The release rate of CAR reached approximately 86.83 ± 1.82 % at pH = 5.0 and reached 88.65 ± 1.86 % in the presence of pectinase (1.0 mg/mL) after 168 h. In addition, the CAR@ZIF-8/TOCNF/Pec film performed superior inhibition efficacy against Escherichia coli, Staphylococcus aureus , and Aspergillus niger . The CAR@ZIF-8/TOCNF/Pec film were highly effective in preserving the freshness of fungus-inoculated raspberries and mangoes, and inhibited the spread of fungal spores during storage for 5 and 7 days, respectively. Therefore, this work provided a promising, smart and eco-friendly strategy for on-demand and precise release of bioactive ingredients during food storage and preservation.
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 10
·1-9
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IF 5.3
Zeng Zhaobin,Wang Haibin,Cai Chongming,Xiang Lin,Zhou Haohuan,Xie Ziyi,Guo Bangming
Methods based on photoelectrochemical immunoassay have been utilized for the quantitative monitoring of neuron-specific antigen (NSE) with neuroblastoma patients, but most provide only low sensitivity. In this contribution, a simple and feasible photoelectrochemical immunoassay based on ZIF-8-derived double-shelled hollow ZnS nanocages (ZnS NCs) was applied to the split-type photocurrent measurement of NSE in biological fluids, accompanied by an enzyme-catalyzed system for synergistic amplification. Glucose oxidase (GOx)-labeled anti-NSE secondary antibody was utilized to form a sandwiched immunoreaction on capture antibody-coated microplate, whereas ZnS NCs with strong and stable photocurrents were employed to generate the detectable photocurrent. Subsequently, GOx catalyzed the glucose substrate to produce hydrogen peroxide, thereby causing the change in the photocurrent of double-shelled hollow ZnS nanocages. Followed by optimizing experimental conditions, the photoelectrochemical immunoassay displayed good photocurrent responses within the dynamic range 1.0–10000 pg mL −1 at a low detection limit of 0.59 pg mL −1 NSE. Good reproducibility and high specificity were acquired for determination of NSE standards. Such a highly favourable analytical performance could be achieved even in human serum samples at different dilutions.
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PubMed
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Membranes
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2025
·Vol. 15
·期 9
·277
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IF 3.6
Lei Ni,Qiancheng Cui,Zhe Wang,Xueting Zhang,Jun Ma,Wenjuan Zhang,Caihong Liu
The inherent hydrophobicity of poly(vinylidene fluoride) (PVDF) ultrafiltration membranes leads to severe membrane fouling when processing proteinaceous solutions and organic contaminants, significantly limiting their practical applications. This study presents a novel metal-ion mediated co-deposition strategy for fabricating high-performance antifouling poly(vinylidene fluoride) (PVDF) hollow fiber ultrafiltration membranes. Through Zn2+coordination-driven self-assembly, a uniform and stable composite coating of dopamine (DA), tannic acid (TA), and ZIF-8 nanoparticles was successfully constructed on the membrane surface under mild conditions. The modified membrane exhibited significantly enhanced hydrophilicity, with a water contact angle of 21° and zeta potential of −29.68 mV, facilitating the formation of a dense hydration layer that effectively prevented protein adhesion. The membrane demonstrated exceptional separation performance, achieving a pure water permeability of 771 L/(m2∙h∙bar) and bovine serum albumin (BSA) rejection of 97.7%. Furthermore, it showed outstanding antifouling capability with flux recovery rates exceeding 83.6%, 74.7%, and 71.5% after fouling by BSA, lysozyme, and ovalbumin, respectively. xDLVO analysis revealed substantially increased interfacial free energy and stronger repulsive interactions between the modified surface and protein foulants. The antifouling mechanism was attributed to the synergistic effects of hydration layer formation, optimized pore structure, additional water transport pathways from ZIF-8 incorporation, and electrostatic repulsion from negatively charged surface groups. This work provides valuable insights into the rational design of high-performance antifouling membranes for sustainable water treatment and protein separation applications.
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2021
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IF 6.953
Dongsheng Fu,Yuanzheng Ding,Ruijie Guo,Jie Zhang,Huifang Wang,Baolong Niu,Hong Yan
ZIF-8, a subclass of metal organic frameworks (MOFs), was employed as the CuO carriers because of its high surface areas and good dispersibility. A novel antibacterial agent CuO@ZIF-8 was synthesized by environmentally-friendly direct calcination strategy, and introduced into the composite double-layer films for packing materials. The double-layer films were prepared via solution casting method with polylactic acid (PLA) and polyvinyl alcohol (PVA)-quaternary ammonium chitosan as the matrix of outer layer and inner layer, respectively; and CuO@ZIF-8 nanoparticles were introduced into the PVA-quaternary ammonium chitosan layer. The double-layer films exhibited superior antibacterial activity resulted from the uniform dispersion of CuO by ZIF-8 carriers. The elongation at break was enhanced and up to 17.13%, about 2.4-fold that of PLA films. Meanwhile, the films provided low water vapor permeability and strong UV-barrier ability which were attributed to the lay-by-layer casting, CuO@ZIF-8 doping and TiO 2 addition. Cherry tomato preservation experiment revealed that the composite films retarded the growth of harmful microorganisms on the fruit surface. MTT assay confirmed the cytocompatibility of the films. The easily fabricated double-layer films presented potential possibility in the field of biodegradable food packaging.
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Metals
·
2026
·Vol. 16
·期 7
·761
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IF 3.1
Haowu Li,Rongjun Yang,Weilin Chen,Weizhou Li,Deli Shen
ZIF-8-modified micro-arc oxidation (MAO) coatings have attracted considerable attention for improving the corrosion resistance of aluminum alloys, owing to their combined barrier and chemical protection effects. In this work, ZIF-8/MAO composite coatings were fabricated via in situ solvothermal growth, and the effects of solvothermal temperature and time on coating evolution and corrosion performance were systematically investigated. The coatings were characterized by field-emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FT-IR). The results show that increasing the solvothermal temperature promotes ZIF-8 formation, which may be related to enhanced coordination reactions and particle growth. Prolonging the solvothermal time induces a transition from ZnO-dominated coatings at 8 h to ZIF-8-dominated structures at 16–24 h, whereas unconverted ZnO is still detected after prolonged growth. The in situ-grown ZIF-8 particles cover the MAO surface and contribute to the sealing of surface micropores and cracks, forming a more compact composite barrier structure. The reduced coating performance at 220 °C or after 32 h may be associated with excessive particle refinement, local structural imperfections, or reduced coating integrity under prolonged or high-temperature solvothermal conditions. Electrochemical impedance spectroscopy (EIS) results reveal that the composite coating exhibits a charge transfer resistance more than one order of magnitude higher than that of the bare MAO coating, indicating significantly enhanced barrier protection. These findings demonstrate that in situ-grown ZIF-8 is an effective strategy for improving the corrosion resistance of MAO coatings on aluminum alloys.
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Advanced Composites and Hybrid Materials
·
2026
·Vol. 9
·期 4
·297
·
IF 15.5
Lv Ze,Fang Yu,Gao Yang,Li Hongwei,Yan Pengkun,Zhang Zheng,Wang Lei,Li Fengyu,Ma Yingjian,Zhao Rui,Guo Xinyu,Wu Xuemin,Xu Yong
Sustainable management of plant bacterial diseases calls for delivery systems that minimize reliance on conventional synthetic pesticides while improving deposition efficiency, on-demand release, and environmental compatibility. This study employs a coordination-driven hollowing strategy to construct interface-optimized hollow metal–phenolic nanocarrier (NaSA@PDA@ZIF-8), achieving synergistic loading of sodium salicylate and Zn 2+ . PDA-induced etching of ZIF-8 generates a well-defined hollow architecture while enhancing hydrophilicity and colloidal stability. The optimized nanocarrier, obtained via Box–Behnken response surface design, achieves a NaSA loading content of 23.90%. Regarding interfacial performance, the carrier exhibits significantly optimized wetting behavior with a contact angle reduced to 51.15°, enhanced dynamic spreading speed, and outstanding leaf adhesion and rain-wash resistance, ensuring effective retention and utilization in complex field environments. Under simulated bacterial wilt conditions in tobacco (acidic pH 5.0 and elevated temperature of 35 °C), the system exhibited enhanced release behavior. The cumulative release of NaSA reached 81.72% and 83.40%, while Zn 2+ release reached 23.19% and 18.72%, indicating good responsiveness to disease-relevant microenvironmental conditions. Its antibacterial activity (EC 50 = 17.80 mg·L -1 ) is likely associated with multiple contributing factors, including Zn 2+ release, potential ROS generation mediated by PDA, and NaSA-related activation of plant defense responses. This work demonstrates a hollow metal–phenolic nanoplatform that integrates interfacial adhesion, stimuli-responsive co-delivery, and biosafety, providing a multifunctional reference model for green plant protection. Graphical abstract
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CHEMICAL ENGINEERING SCIENCE
·
2026
·
IF 5.1
Simin Li,Sen Mu,Jie Ji,Fengbing Tang,Ning Chai,Jingbo Mu,Handan Zeng
Tetracycline hydrochloride (TCH), owing to its structural stability and resistance to degradation, has emerged as a typical persistent pollutant in aquatic environments. However, the development of effective and environmentally friendly strategies for the removal of TCH remains highly challenging, owing to limited pollutant enrichment and low catalyst activation efficiency. In this study, a quartz sand-supported ZIF-8 catalyst functionalized with chitosan-derived N-doped carbon (QN@ZIF-8) was rationally constructed: (1) π–π interactions enhanced the adsorption and enrichment of TCH molecules, thereby significantly increasing the probability of contact between pollutants and active sites and (2) its efficient electron transfer channels accelerated the activation of peroxymonosulfate (PMS), facilitating the directional generation of superoxide radicals (•O 2 − ) and singlet oxygen ( 1 O 2 ), thus strengthening the synergistic pathways of both radical and non-radical degradation. Experimental results demonstrated that under optimal conditions (catalyst dosage: 0.5 g/L, PMS: 0.2 g/L, pH ≈ 5.1), QN@ZIF-8 achieved an efficient removal of 90.5% of TCH within 40 min, with an apparent pseudo-first-order rate constant of k = 0.0393 min −1 , which was 2.1 times higher than that of pristine quartz sand. Moreover, the catalyst maintained a removal efficiency above 82.3% after five consecutive cycles and exhibited stable performance in tap water and simulated seawater. Liquid chromatography-mass spectrometry (LC-MS) revealed three predominant TCH degradation pathways. This study not only elucidates the π-system-driven synergistic catalytic mechanism but also offers new insights into material design and theoretical guidance for the efficient remediation of recalcitrant organic pollutants
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International Journal of Nanomedicine
·
2026
·
IF 8.7
Zidong Wu,Kai Ma,Zixuan Wu,Xiaoyu Guo,Yuning Qu,Zheyue Zhu,Weidong Zhu,Chengxin Li,Yi Liu,Rui Ma,Pei Yang
Background Polyetheretherketone (PEEK) is a promising orthopedic implant material due to its bone-matched elastic modulus and radiolucency. However, its clinical application is limited by biological inertness and lack of antibacterial activity, which predispose to implant-associated infection (IAI) and poor osseointegration. This study developed a multifunctional coating on sulfonated PEEK (SPEEK) via polydopamine (PDA)-mediated co-delivery of simvastatin-loaded ZIF-8 nanoparticles (SIM@ZIF-8) and moxifloxacin (MOX) to address these limitations.Methods A time-programmed release coating was fabricated on SPEEK by embedding SIM@ZIF-8 within a PDA layer and surface-loading MOX onto the surface. The coating’s physicochemical properties, drug release profiles, biocompatibility, antibacterial activity, and osteogenic capacity were evaluated in vitro. Antibacterial efficacy and osseointegration were further assessed in vivo using rat subcutaneous infection and rabbit femoral defect models.Results Release profiles revealed that MOX exhibited burst release within 24 h, whereas SIM quickly reached therapeutic concentrations during the initial phase and was slowly released over five weeks, while Zn2+ from ZIF-8 was released synchronously with SIM. In vitro antimicrobial assays showed that the synergistic release of MOX and SIM exhibited potent antibacterial activity against Staphylococcus aureus and Escherichia coli, providing sustained inhibition of Staphylococcus aureus biofilms. The coating also promoted MC3T3-E1 cell adhesion, spreading, and osteogenic differentiation, as indicated by upregulated osteogenic markers (Runx2, OCN, OPN, COL1A1), enhanced matrix mineralization, and increased BMP-2 expression. In rat models, bacterial colonization on the coated surface and residual bacteria in tissues were significantly reduced. In rabbit femoral defects, sustained co-release of SIM and Zn2+ accelerated new bone formation and improved osseointegration, confirmed by micro-CT, double fluorescence labeling, and histological analysis.Conclusion This study presents a novel bioactive PEEK implant coating integrating antibacterial and osteogenic functions through a MOX/SIM@ZIF-8/PDA system. The strategy effectively combats IAI and enhances osseointegration, offering potential for clinical orthopedic applications.
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Materials Today Communications
·
2026
·
IF 4.9
Wenhui Pei,Xiaofei Li,Haojun Chen,Xiangrong Guo,Jinhui Pang,Yingjie Du,Yuanyuan Xie,Peng Wang,Caoxing Huang
The intertwined pathology of bacterial infection and dysregulated inflammation represents a major barrier to the healing of full-thickness skin wounds. Nanocarriers such as zeolitic imidazolate framework-8 (ZIF-8) provide efficient platforms for localized and pH-dependent drug delivery. In this study, a ZIF-8 nanoparticle system co-embedded with vancomycin (Van) and iron oxide nanoparticles (IONPs), termed Van-IONPs@ZIF-8, was engineered to combine antibacterial and inflammation-modulating functions. In vitro experiments demonstrated growth-inhibitory activity against Staphylococcus aureus ( S. aureus ) and modulation of inflammatory cytokine expression in LPS-stimulated RAW 264.7 macrophages, with TNF-α mRNA expression decreased by 67% and IL-10 mRNA expression increased by 244%. The nanocomposite was incorporated into a triple-crosslinked hydrogel matrix, and the resulting Van-IONPs@ZIF-8-Gel exhibited sustained and pH-dependent Van release under the tested conditions. In a rat full-thickness S. aureus -infected wound model, Van-IONPs@ZIF-8-Gel treatment was associated with improved wound closure, lower recoverable bacterial colony counts, attenuated inflammatory markers, and increased collagen-positive area. These findings provide proof-of-concept evidence supporting Van-IONPs@ZIF-8-Gel as an integrated antibacterial and inflammation-modulating platform for infected-wound management. Download: Download high-res image (248KB) Download: Download full-size image An engineered ZIF-8 composite hydrogel co-delivering vancomycin and iron oxide nanoparticles provides combined antibacterial and inflammation-modulating functions.
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Applied Materials Today
·
2026
·
IF 7
Xiaowan Zhao,Qikai Qiao,Yuanqing Li,Aiqin Zhang,Hong Guo,Jing Guo,Haixia Zhang,Jianjun Lu
To address the issue of secondary contamination caused by the lack of antibacterial properties in polypropylene (PP) meltblown nonwoven fabrics while preserving its core filtration performance, this work employed an immersion-ultrasonic method to construct Ag@T-ZIF-8 antibacterial materials with a core-shell structure. Subsequently, PP/Ag@T-ZIF-8-G composite meltblown fibers was prepared via covalent modification and meltblown spinning technology. The systematic characterization of Ag@T-ZIF-8 was conducted in terms of its chemical structure, microstructure, and photocatalytic antibacterial performance. The effects of Ag@T-ZIF-8 on the antibacterial, filtration and comfort properties of the composite melt-blown nonwoven fabrics were investigated, and the enhancement mechanisms of antibacterial and filtration were revealed. The results indicate that Ag@T-ZIF-8 exhibits a uniform core-shell structure with a particle size of 40∼50 nm and a specific surface area of 531.83 m²/g. At an antibacterial concentration of 200 mg/L, it achieves a 99.99% antibacterial rate against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) within 8 min in the dark or 4 min under illumination. Compared with PP meltblown nonwoven fabrics, it demonstrates 73.31% in filtration efficiency for particles with a pressure drop of only 37.3 Pa. When Ag@T-ZIF-8 loading reaches 1 wt%, the composite meltblown fabrics completely eliminates E. coli and S. aureus after 160 min of illumination or 240 min in the dark. This outstanding comprehensive filtration performance stems from a synergistic filtration mechanism combining mechanical filtration, ionic adsorption, and dual-mode antibacterial action under light or dark condition. Integrating superior filtration capabilities, broad-spectrum antibacterial properties, and wear comfort, PP/Ag@T-ZIF-8-G meltblown nonwoven fabrics deliver a highly efficient integrated antibacterial-filtration solution for the medical protective field.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2026
·
IF 9.1
Hao Zhan,Wenlong Chen,Xingyu Pei,Hao Wang,Bing Zhao,Xiefei Wang,Qingqing Liang,Yukang Xu,Weiwei Zhu
Highly diffuse cationic dyes and copper ions are normal pollutants in dye wastewater and pose a potential ecological risk, threatening human health. However, current MOF-based fibrous composites usually scarify their stability of active sites for photocatalytic reaction, which inevitably causes nondurable removal of these diffuse particles. Here, an in situ growth strategy was proposed to fabricate robust core-shell heterostructure of ZnO@ZIF-8 nanorods which were anchored within polytetrafluoroethylene (PTFE) micro-scale fibers by the solution-blowing spinning (SBS) technique to achieve ZnO@ZIF-8/PTFE hierarchical fibrous networks (ZZP-HFN). It presents superior degradation of cationic dyes (over 97%) and durable decompose stability of more than 20 cycles, and prominent adsorption capacity for copper ions (86.53 mg/g). Moreover, contrast to the existing MOF-based fibrous membranes, ZZP-HFN exhibits the self-cleaning performance on account of its stable composite structure between ZnO@ZIF-8 nanorods and PTFE fiber. The cationic dyes removal of ZZP-HFN from wastewater is attributed to the synergistic effect of adsorption and photocatalytic ability. This work provides an insight to design advanced MOF-based composites with durable photocatalytic performance for dye wastewater purification.
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