JOURNAL OF APPLIED POLYMER SCIENCE
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2013
·Vol. 129
·期 6
·3459-3465
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IF 1.395
Shen Liu,Shenghe Liu,Xudong Liu,Jingwen Zhao,Wenguo Cui,Cunyi Fan
Electrospun fibrous membranes have been used frequently in biomedical applications, but their simultaneous use as antibacterial agents and in the prevention of cell adhesion on repaired tendons after injury has not been investigated. In this study, silver-nanoparticle (SN)-loaded poly( L -lactide) (PLLA) fibrous membranes were prepared by the electrospinning of SNs into PLLA fibers. Micrograph results showed that these membranes were composed of electrospun fibers and that the fibers were incorporated with SNs. From the results of X-ray diffraction and thermogravimetry, we concluded that the SNs were physically mixed into the fibers at the desired content. The mechanical properties were not significantly changed. The preliminary antibacterial effects on Staphylococcus epidermidis and Staphylococcus aureus and the synergistic antiproliferative effects of the SN-loaded PLLA fibrous membranes were observed. Taken together, these results demonstrate that SNs can be directly loaded onto a biodegradable PLLA fibrous membrane via electrospinning to achieve proper material properties with preliminary potential as antibacterial antiadhesion barriers for tendon injury. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2013
·Vol. 130
·期 2
·939-943
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IF 1.395
Lin Wang,Guangyou Zhang,Meishan Pei,Linlin Hu,Enyong Li,Huizhi Li
A lable-free, simple, and sensitive fluorescence “turn-on” approach is designed to rapidly detect protein using a conjugated polythiophene derivative (PDPMT-Cl). The fluorescence of PDPMT-Cl solution can be efficiently quenched by PtCl42− ions. Upon adding trypsin to the (bovine serum albumin, BSA) PDPMT-Cl–PtCl42− solution, the BSA is cleaved into amino acid or peptide fragments, which are stronger PtCl42− ions chelators to form more stable complexes with PtCl42− ions. Thus, the PtCl42− ion is displaced from PDPMT-Cl and the fluorescence of PDPMT-Cl is recovered. By triggering the “turn-on” signal of PDPMT-Cl, it is successful to detect the protein in real time. “Turn-on” response as readout signal is able to effectively reduce background noise and increase detection sensitivity. This method offers good selectivity for detecting protein in the presence of other common amino acids and metal ions. Under optimized conditions, the concentration of BSA in the range of 0.0004–1.75 mg/mL exhibits a linear relationship with the relative fluorescence intensity, and the correlation coefficient is 0.9997. The limit of detection is 4.47 × 10−4 mg/mL. The system is successfully applied for detecting protein in milk and egg. Due to the simplicity, sensitivity, and rapid response, this assay shows great potential for protein detection in the future. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 939-943, 2013
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2013
·Vol. 130
·期 2
·869-876
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IF 1.395
Xiao-Jing Li,Shi-An Zhong,Cui-E Li
An azobenzene-containing molecularly imprinting polymer microsphere with photoresponsive binding properties toward 2,4-dichlorophenoxyacetic acid (2,4-D) was successful prepared via silica surface polymerization. The number-average diameters of silica and imprinting polymer microsphere are 0.5 and 0.7 μm, respectively. The static adsorption, binding and selectivity experiments were performed to investigate the adsorption properties and recognition characteristics of the polymers for 2,4-D. The equilibrium adsorptive experiments indicated that 2,4-D-SMIP(surface molecularly imprinted polymers) has significantly higher adsorption capacity for 2,4-D than its nonimprinted polymers (SNIP).The binding constant K d and apparent maximum number Q max of the imprinted polymer were determined by Scatchard analysis as 0.054 mmol L −1 and 0.167 mmol g −1 , respectively. The result of photoregulated release and uptake of 2,4-D experiment demonstrated that azo-containing SMIP can make use of light and change it into mechanical properties to release and take up the template molecules. It means that the SMIP can be controlled by light. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 869-876, 2013
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2013
·Vol. 130
·期 1
·631-637
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IF 1.395
Hongtao Liu,Jiangang Zhou,Xiuying Liu,Danying Zuo,Shaojin Gu,Weilin Xu
Biomedical polyurethane (BPU) and silk fibroin have similarly molecular architecture in their primary and aggregate structure, both of which have amide bonds and microphase separation, and they have been employed as scaffold materials for biomedical applications. Based on this, as the featured peptide sequence of silkworm silk fibroin, GlycineAlanineGlycineAlanine (GlyAlaGlyAla) tetrapeptide was synthesized by using traditional liquid-phase peptide synthesis method with Boc-protected glycine and alanine as starting materials, and was transformed to its derivative with two amine-terminated functional groups. The derivative was introduced as a chain extender into the backbone to form the hard segment of a silk-inspired PU with urea-linkage. Related measurements show that molecular weight of the synthesized silk-inspired PU ranged from 13,000 to 15,000. Fourier transform infrared (FTIR) absorption bands of Amides I and II are at 1651 cm −1 and 1534 cm −1 , and Raman absorption band of Amide III is at 1302 cm −1 . UV-Vis absorption peak of the silk-inspired PU is at 266 nm. This new concept and strategy may allow the fabrication of a new class of thermoplastic polyurethane elastomers to mimic the structure and properties of silk fibroin of silkworms and spiders. Information provided by this study may be used to better understand the correlation between the natural and man-made materials. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2013
·Vol. 129
·期 6
·3373-3381
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IF 1.395
Xiaoxu Liang,Qiting Huang,Fang Liu,Jingwei He,Zhengmei Lin
To prepare antibacterial dental resin, a series of novel urethane dimethacrylates quaternary ammonium methacrylate monomers (UDMQAs) with different substituted alkyl chain length were synthesized, and their structures were confirmed by FTIR and 1 H-NMR spectra. The obtained UDMQAs were used to replace 2,2-Bis[4-(2-hydroxy-3-methacryloyloxypropyl)-phenyl]propane (Bis-GMA) totally as base monomers of dental resin and mixed with Tri-ethyleneglycol dimethacrylate (TEGDMA) at the mass ratio of 50/50. The properties of these prepared resins like antibacterial activity, double bond conversion (DC), polymerization shrinkage, flexural strength (FS), and modulus (FM), water sorption and sol fraction were investigated. The most commonly used dental resin Bis-GMA/TEGDMA (50wt/50wt) was chosen as a reference. The results showed that UDMQAs could endow dental resin with antibacterial activity. Compared with Bis-GMA-based dental resin, UDMQAs-based resin had the same or higher DC, lower polymerization shrinkage, lower flexural strength and modulus, and higher water sorption and sol fraction. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2012
·Vol. 129
·期 2
·767-772
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IF 1.289
Dagen Zhong,Zonghua Liu,Shasha Xie,Wei Zhang,Yuanming Zhang,Wei Xue
This work is to develop a novel dual drug delivery system that can simultaneously load and release 18β-glycyrrhetinic acid (GA, a hydrophobic drug) and bovine serum albumin (BSA, hydrophilic model drug) in a single formulation. The system consists of poly( D,L -lactic) (PDLLA) microspheres embedded in calcium alginate hydrogel beads. The GA-loaded microspheres were first prepared and then dispersed in the aqueous solution of sodium alginate and BSA. The resulting suspension was dropped into aqueous calcium chloride solution to obtain the dual drug delivery system. The morphology of the microspheres and beads, the drug content and loading efficiency, the interaction between GA and PDLLA, and the drug release behaviors were studied. Scanning electron microscope (SEM) revealed that the PDLLA microspheres were homogeneously distributed in the beads. Differential scanning calorimetry (DSC) measurement suggested certain interaction between GA and PDLLA, and the crystal structure of GA was influenced by the polymer. The dual release in vitro showed a rapid BSA release but a sustained GA release in all the systems. Furthermore, the release rate of BSA was accelerated by increasing PDLLA/alginate ratio, while the release rate of GA was decreased, and the release of both hydrophobic and hydrophilic drugs could be adjusted by changing the ratio of PDLLA/alginate. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 20122
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2012
·Vol. 129
·期 3
·1131-1142
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IF 1.289
Shitong Ren,Hefei Chang,Lijuan He,Xiaofei Dang,Yanyan Fang,Liaoyun Zhang,Huayi Li,Youliang Hu,Yuan Lin
A series of star block polymers with a hyperbranched core and 26 arms are successfully synthesized by atom transfer radical polymerization of styrene (St), and poly(ethylene glycol) methyl ether methacrylate from a hyperbranched polystyrene (HBPS) multifunctional initiator. All-solid polymer electrolytes composed of these multiarm star polymers and lithium salts are prepared. The influences of polyoxyethylene (PEO) side-chain length, PEO content, lithium salt concentration and type, and the structure of polymer on ionic conductivity are systematically investigated. The resulting polymer electrolyte with the longest PEO side chains exhibits the best ionic conductive properties. The maximum conductivity is 0.8 × 10 −4 S cm −1 at 25°C with EO/Li = 30. All the prepared multiarm star block polymers possess good thermal stability. The mechanical property is greatly improved owing to the existence of polystyrene blocks in the multiarm star polymer molecules, and flexible films can be obtained by solution-casting technique. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2012
·Vol. 129
·期 2
·773-778
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IF 1.289
Changdao Mu,Xinying Li,Jimin Guo,Caixia Bi,Defu Li
To improve the thermal and mechanical properties of gelatin-polyethylene glycol (PEG) composite fibers, montmorillonite (MMT) is incorporated into gelatin-PEG composite fibers during gel-spinning process. The effects of MMT on the structure and properties of gelatin-PEG composite fibers are investigated. The viscosimetry analysis and transmission electron microscopy measurements show that MMT has a good dispersion in spinning solution at low loading, while serious aggregation is observed with excess amount of MMT adding. The data of X-ray diffraction (XRD) show that MMT can be intercalated and exfoliated in gelatin-PEG-MMT nanocomposite fibers. Fourier transform infrared (FTIR) studies show the hydrogen bonding interactions between gelatin and MMT. The mechanical properties, differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) measurements indicate that the mechanical and thermal properties of nanocomposite fibers are improved as expected at low loading of MMT. However, excess amount of MMT decreases the mechanical and thermal properties of nanocomposite fibers due to poor dispersion and clay cluster induced gelatin chains aggregation. Moreover, it is found that the mechanical properties of gelatin-PEG-MMT nanocomposite fibers may be more sensitive to conformational change of gelatin molecules caused by the addition of MMT. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2012
·Vol. 129
·期 2
·689-698
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IF 1.289
Qingchun Zhang,Yan Zhang,Meidong Lang
Microsphere systems have been used to deliver drugs, proteins, and cells. However, dispersed microspheres can induce harmful effects after they are introduced into the body. To agglomerate these dispersed microspheres, an in situ forming system was developed to fabricate microsphere/hydrogel composites. Polycaprolactone microspheres with a porous surface and hollow core were physically incorporated into a genipin-crosslinked gelatin hydrogel. The incorporation of microspheres reduced the swelling capacities and weakened the unexpected volume expansion, which is not favorable for in vivo implants. Additionally, the reacted genipin ratio increased with increasing gelatin concentration. The degradation of the composite was also determined, and it was proposed that the degradation mechanism of the composite was bulk collapse, whereas that for the pure hydrogel was surface erosion. The obtained microsphere/hydrogel composite might have a great potential application as an injectable system for tissue regeneration. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2012
·Vol. 129
·期 1
·187-192
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IF 1.289
Chao Yang,Zhen-Guo Yang
A novel photosensitive low viscosity epoxy resin was synthesized by polyethylene glycol (PEG)-modified bisphenol-A epoxy resin (E51). The resin was modified by ethylene glycol, diethylene glycol, and different molecule weights (200,300,400) PEGs to optimize the minimum viscosity. FTIR was used to determine molecule structure. Cationic photoinitiator (UVI-6976) mixed with modified resin (10 wt %), was utilized to boost the resin curing under UV light. The curing degree was beyond 90% within 40 s and the whole process was monitored by photo-DSC. The modified resin diluted with ethylene glycol diglycidyl ether, was screen printed onto polyimide and polyethylene terephthalate substrate, and the properties of solder mask were up to China printed circuit association standard. The solder resist also meet all requirements under ink-jet printing technology as the viscosity is under 60 mPa·s and the curing duration is <1 min. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2014
·Vol. 132
·期 12
·
IF 1.64
Qi Li,Yiquan Chen,Xinpu Song,Yingpeng Xie,Qiong Hou,Guang Shi
By adjusting the molar ratios of antistatic monomer of octyl phenol ethylene oxide acrylate (denoted as AS), rigid monomer of methyl methacrylate (denoted as MMA), and flame-retardant monomer of 2-(phosphoryloxymethyl oxyethylene) acrylate (denoted as FR), a series of flame-retardant antistatic copolymers poly (octyl phenol ethylene oxide acrylate-co-methyl methacrylate-co-phosphoryloxymethyl oxyethylene acrylate) (donated as AMF) were synthesized through radical polymerization. Among the obtained copolymers, two copolymers, AMF162 (the feed molar ratio of AS, MMA, and FR as 1 : 6 : 2) and AMF1104 (the feed molar ratio of AS, MMA, and FR as 1 : 10 : 4) with different concentrations were added into polypropylene (PP) to prepare PP-AMF162 and PP-AMF1104 series of composites. The thermal stability, limiting oxygen index, the antistatic property, and mechanical properties of PP composites were tested and analyzed. PP-AMF162 series composites have excellent antistatic effect. When the AMF162 content was equal to or <15 wt %, the impact strength of PP-AMF162 composites was higher than that of pure PP. The results indicated that copolymer AMF162 was a suitable flame-retardant and antistatic additive for PP. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132 , 41677.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2014
·Vol. 132
·期 11
·
IF 1.64
Jinbo Jin,Dongqing Liu,Dandan Zhang,Yuhang Yin,Xinyu Zhao,Yufeng Zhang
A hydrophilic compound, taurine, was investigated as an additive in the interfacial polymerization between piperazine (PIP) and trimesoyl chloride (TMC) to prepare thin-film composite (TFC) membranes. The resulting membranes were characterized by X-ray photoelectron spectroscopy and attenuated total reflectance–Fourier transform infrared spectroscopy. The morphology and hydrophilicity of the membranes were investigated through scanning electronic microscopy and water contact angle measurements. The separation performance of the TFC membranes was investigated through water flux and salt rejection tests. The protein-fouling resistance of the films was evaluated by water recovery rate measurements after the treatment of bovine serum albumin. The membrane containing 0.2 wt % taurine showed the best performance of 92% MgSO 4 rejection at a flux of 31 L m −2 h −1 and better antifouling properties than the PIP–TMC membranes. An appropriately low concentration of taurine showed the same MgSO 4 rejection as the PIP–TMC membranes but a better fouling resistance performance. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132 , 41620.
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高影响因子
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