CHEMICAL ENGINEERING JOURNAL
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2021
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IF 13.273
Chengyuan Sun,Xuelian Zeng,Shihang Zheng,Yulan Wang,Zhiyu Li,Haining Zhang,Lanlan Nie,Yufeng Zhang,Yanbing Zhao,Xiangliang Yang
For clinical traumas and surgeries, adhesives that can be used in humid environments is considerably challenging. Inspired by the adhesive proteins of mussel, a gallic acid-modified chitosan-based (CS-GA) hydrogel was prepared through discharge plasma technology, which was first reported to realise polysaccharide-macromolecule-grafted phenolic acids. CS-GA hydrogels with different grafting amounts were successfully prepared, and their structures were characterised using ultraviolet, 1 H nuclear magnetic resonance and Fourier-transform infrared spectroscopy. The modified material exhibited excellent antioxidant properties, which were verified using classical DPPH radical scavenging and reducibility experiments. CS-GA was oxidised in air under physiological conditions and cross-linked to form a hydrogel, with unusual toughness and adhesion properties. The high biocompatibility and haemocompatibility of this hydrogel were showed through cytotoxicity and haemolysis experiments. Furthermore, the abilities of the hydrogel to promote wound healing and haemostasis were evaluated using in vivo rat whole layer skin defect and liver haemorrhage models, respectively. These abilities can provide many possibilities for the development of multifunctional biomedical adhesives.
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POLYMER ENGINEERING AND SCIENCE
·
2023
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IF 3.2
Jingyu Du,Junzhuo Sun,Daohai Zhang
As one of the most common pollutants in wastewater, heavy metals seriously threaten human health and survival, and among the current removal methods, the adsorption method has attracted the most attention because of its simple and safe operation. Zeolite is a substance with a unique spatial structure, cheap cost, and environmental friendliness. Zeolite is a substance with a unique spatial structure, cheap cost, and environmental friendliness. Due to its size and high surface area-to-volume ratio, zeolite exhibits excellent adsorption and ion exchange properties and is a promising adsorbent. In this paper, the modified zeolite chitosan composite film was prepared by solution method by dissolving chitosan in acetic acid solution as the solvent, and the effects of zeolite content, modifier type, initial pH, pore-making agent, adsorption time, adsorption temperature, initial concentration, and feeding amount were studied. The optimal conditions for Pb 2+ adsorption were 40% modified zeolite content, 293 K in 100 mg/L solution, a feeding amount of 1 g/L, pH = 5.5, and a removal rate of 96.6% in 24 h. The isotherm is consistent with the Langmuir adsorption model, which is manifested as single-molecule chemical adsorption, and the highest saturated adsorption capacity is 139.6 mg/g. After five cycles, it still has a greater than 90% initial adsorption effect. Highlights Chitosan-modified zeolite composite membranes are inexpensive. After adsorption, the sorbent is easy to recover.
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CARBOHYDRATE POLYMERS
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2023
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IF 11.2
Yanghui Song,Guanglei Zhao,Sihan Zhang,Chong Xie,Runde Yang,Xiaofeng Li
Separators are indispensable components in lithium-ion batteries (LIBs), providing efficient pathways for lithium ions to travel and isolating the positive and negative electrodes to avoid short circuits. However, traditional polyolefin-based separators exhibit inferior electrolyte affinities, limited porosities, and low thermal stabilities. In this study, a novel method was developed to prepare chitosan micro/nanofiber membranes as LIB separators using natural materials. The pore sizes of the chitosan micro/nanofibers separators were modulated by changing the diameters of the chitosan fibers. The results demonstrated that the chitosan nanofiber separators (CSNFs) had superior electrolyte uptake (281 %), excellent thermal dimensional stability, and electrochemical performance in LiFePO 4 /Li half-cell, as indicated by the higher discharge capacity after 100 cycles, and higher rate capacity than commercial Celgard2325 separator. This study paves the way for the fabrication of eco-efficient and environment-friendly separators for high-performance LIBs.
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Journal of Food Measurement and Characterization
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2023
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IF 3.4
Xu Ya,Ji Zheng,Wei Bangchang,Kong Shengnan,Wang Yang,Li Chuanrun,Wang Huchuan
Propolis has a wide range of biological activity, as a drug in the world has a long history. In this study, the components of propolis essential oil (PEO) were analyzed by gas chromatography-mass spectrometry (GC-MS), and 62 compounds were identified. The main components were β-eudesmol (15.16%), γ-eudesmol (12.35%), α-Bisabolol (11.88%) and guaiol (10.14%). The modified chitosan/hydroxyapatite biomimetic (PMCH) material was prepared to load PEO (PMCH/PEO). Moreover, the optimum preparation process was explored: the mass ratio of material to essential oil was 3:1 (w/w), the ratio of hydroxyapatite to chitosan in load material was 2:1 (w/w), and the time was 40 min. PMCH/PEO showed good storage stability at room temperature. In addition, the antioxidant capacity of PEO and PMCH/PEO was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2’-diazo-bis-3-ethylbenzothiazoline-6- sulfonic acid (ABTS) and ferric reducing antioxidant power (FRAP) assays. The results showed that PEO and PMCH/PEO had significant antioxidant capacity. PEO and PMCH/PEO could significantly inhibit the secretion of nitric oxide (NO), interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF-α). The inhibition of PMCH/PEO on NO, IL-6 and TNF-α can reach 7.61%, 10.92% and 11.79%, respectively. PMCH/PEO biomimetic material could successfully load PEO. PMCH/PEO have good antioxidant and anti-inflammatory activity and can be effectively used in food, pharmaceutical and other industries.
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E-POLYMERS
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2023
·Vol. 23
·期 1
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IF 3.7
Xiaoyu Jie,Bing-Chiuan Shiu,Huazhong Wu,Yuchi Zhang,Yuansong Ye,Chunxiang Lin,Run Fang
Chitosan (CS) is widely used in the treatment of wastewater containing metal ions. However, the poor stability in acidic aqueous solutions severely limits its application in many practical scenarios. In this work, a CS-based composite nanofiber membrane was prepared by electrospinning using urushiol, a natural biomaterial, as the cross-linking agent. The application of the CS-urushiol (CS-U) membrane in the adsorption and recovery of Cr( vi ) in wastewater was systematically studied. The CS-U membrane showed great resistance to strongly acidic and oxidative environments, and the adsorption process combined two mechanisms of electrostatic attraction and redox reaction. Due to the nanoscale fibers, porous structure, and strong acid resistance, the CS-U membrane adsorbed Cr( vi ) rapidly and efficiently in both batch and continuous modes. Moreover, the adsorption capacity and selectivity of the CS-U membrane for Cr( vi ) could be maximized simultaneously by adjusting the solution pH, promoting the recovery of high-purity Cr 2 O 3 .
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Jian Wu,Jinzhe Chang,Jun Liu,Jiajian Huang,Zixia Song,Xiaofeng Xie,Liting Wei,Jiaxin Xu,Suqing Huang,Dongmei Cheng,Youzhi Li,Hanhong Xu,Zhixiang Zhang
A chitosan-based nanoparticle was prepared using chitosan (CS) and O -carboxymethyl chitosan ( O -CMCS). Our study revealed that chitosan/ O -carboxymethyl chitosan/tebuconazole nanoparticles (CS/ O -CMCS/TBA NPs) exhibited superior antifungal activity, foliar adhesion, and microbial target adhesion performance compared to commercial suspension concentrate (SC). The antifungal activity of CS/ O -CMCS/TBA NPs against C. gloeosporioides , with a 3.13-fold increase in efficacy over TBA (SC). We also found that low concentrations of CS/ O -CMCS NPs promoted the growth of C. gloeosporioides and enhanced the fungal catabolism of chitosan. Overall, the CS/ O -CMCS/TBA NPs were found to possess the remarkable capability to selectively aggregate around pathogenic microorganisms and CS/ O -CMCS NPs can enhance the fungal catabolism of chitosan. CS/ O -CMCS/TBA NPs, as a “sugar-coated bomb”, was a promising asset for effective plant disease management and pesticide utilization through the affinity of chitosan-based nanoparticles and C. gloeosporioides , enabling targeted delivery and targeted release of their encapsulated active ingredient, which was important for the development and application of biocompatible chitosan-based nanopesticides.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
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IF 8.2
Rong Chang,Donghui Zhao,Chen Zhang,Kaiyue Liu,Yuanmeng He,Fangxia Guan,Minghao Yao
Melanoma excision surgery is usually accompanied by neoplasm residual, tissue defect, and bacterial infection, resulting in high tumor recurrence and chronic wound. Nanocomposite hydrogels can satisfy the twin requirements of avoiding tumor recurrence and skin wound healing following skin melanoma surgery due to their photothermal anti-tumor and anti-bacterial activities. In this study, carboxymethyl chitosan, oxidized fucoidan and polyphenol–metal nanoparticle (PMN) of tannic acid capped gold nanoparticles were used to fabricate multifunctional nanocomposite hydrogels through Schiff base reaction. The prepared hydrogel demonstrated outstanding photothermal effect, and the controlled high temperature will rapidly kill melanoma cells as well as bacteria within 10 min. Good injectability, self-healing and adhesion combined with high reactive oxygen species (ROS) scavenging capacity, hemostasis and biocompatibility made this hydrogel platform perfect for the postoperative treatment of melanoma and promoting wound healing. With the assistance of NIR irradiance, hydrogel can inhibit tumor tissue proliferation and promote tumor cell apoptosis, thereby helping to prevent melanoma recurrence after surgical removal of tumors. Simultaneously, the irradiance heat and polyphenol component kill bacteria on the wound surface, eliminate ROS, inhibit inflammatory responses, and promote angiogenesis, collagen deposition, and skin regeneration, all of which help to speed up wound healing.
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Journal of Cleaner Production
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2023
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IF 11.1
Yaopeng Zhang,Miaojia Du,Hui Chen,Chensi Shen,Mengmeng Lou,Chenye Xu,Chunyan Ma,Fang Li
Adsorption enrichment coupled with oxidative degradation is a promising technique for eliminating tetracycline (TC) from an aqueous environment . However, the high cost associated with this technique limits its applicability. Thus, in this study, we synthesized Cu 2 O and CuFe 2 O 4 bimetallic-modified chitosan particles (Cu(I)–CuFe 2 O 4 @CS) with high adsorption efficiency and self-cleaning performance. The self-cleaning performance was driven by the in-situ generated reactive oxygen species (ROS). Batch experiments and characterization methods indicated that 97.39% of TC was rapidly adsorbed on the particles surface and subsequently degraded by in-situ generated ROS, to achieve a self-cleaning process. The Cu(I)–CuFe 2 O 4 @CS/TC system exhibited maximum O 2 • - and H 2 O 2 concentration of 12.95 μmol/L and 42.05 μmol/L, respectively. Cu 2 O was the main source of the ROS generation, while CuFe 2 O 4 effectively adsorbed TC and contributed to the synergistic accumulation of ROS. Moreover, the adsorbed TC with reductive functional properties facilitated the reduction of Fe(III)/Fe(II) and Cu(II)/Cu(I) cycles, thereby improving TC elimination efficiency.
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Polymers
·
2023
·Vol. 15
·期 19
·4011
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IF 5
Huan-Jun Lu,Jian-Ke Cen,Yu Ren,Mei-Xian Li
Nanoparticle delivery of functional molecules or vaccines is an effective method for the treatment of many diseases. This study aims to design ginsenoside Rh2-conjugated O-carboxymethyl chitosan (O-CMC/Rh2) as a drug delivery system and explore its anti-nociceptive effects. O-CMC/Rh2 was synthesized with an esterification reaction, and its chemical composition and morphology were evaluated using proton nuclear magnetic resonance (1H NMR), the attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy, and scanning electron microscopy (SEM). In addition, the in vitro cumulative release of Rh2 from the O-CMC/Rh2 was also evaluated under different pH conditions. The results showed that the ginsenoside Rh2 was successfully conjugated to the O-CMC matrix and exhibited a highly porous structure after conjugation, facilitating the release of Rh2 from O-CMC. Complete Freund’s adjuvant (CFA) and burn injury-induced pain models were used to evaluate the anti-nociceptive effects of O-CMC/Rh2 on inflammatory pain. O-CMC/Rh2 reduced CFA-induced pain hypersensitivity in a dose-dependent manner and had a longer analgesic effect than Rh2. In addition, O-CMC/Rh2 also relieved the chronic pain induced by bury injury. These results indicated that O-CMC/Rh2 could be useful in reducing inflammatory pain, thus possessing a potential medicinal application in pain therapy.Keywords:O-carboxymethyl chitosan;ginsenoside Rh2;anti-nociception;inflammatory pain
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ACS Applied Materials & Interfaces
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2023
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IF 9.5
Jinghua Yu,Qingqing Zhu,Wenli Ma,Yajie Dai,Shuhuan Zhang,Fanghui Wang,Hong Zhu
The present paper studied the chitosan-doped composite diaphragm by the phase exchange method with the objective of developing a composite diaphragm that complies with the alkaline water electrolysis requirements, as well as tested the electrolytic performance of the diaphragm in alkaline water electrolysis. The structure and morphology are characterized by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). The performance of chitosan-doped composite diaphragms was tested; CS3Z12 composite diaphragm with a low area resistance (0.20 Ω cm2), a high bubble point pressure (2.75 bar), and excellent electrochemical performance (current density of 650 mA cm–2 at 1.83 V) shows the best performance. Moreover, the performance of the synthesized composite diaphragm is significantly elevated compared to commercial diaphragms (Zirfon PERL), which is promising for practical application in alkaline electrolytic cells.
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POLYMERS FOR ADVANCED TECHNOLOGIES
·
2015
·Vol. 26
·期 8
·924-931
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IF 1.757
Feng Su,Jingzhao Wang,Shoujin Zhu,Shuilian Liu,Xiaoqin Yu,Suming Li
Novel carboxymethyl chitosan-polylactide (CMCS- g -PLA) hydrogels were prepared by using 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) as crosslinking agent and catalyst at room temperature. Solid-state 13 C-NMR, SEM, and FT-IR measurements showed that PLA blocks are successfully grafted onto the CMCS main chains. DSC measurements confirmed the effective crosslinking of carboxymethyl chitosan. With increasing the amount of EDC/NHS, the crosslink destiny of CMCS- g -PLA copolymers is improved. The swelling ratio of CMCS- g -PLA hydrogels is pH dependent, showing a minimum in the pH range of 3 to 5. Rheological studies confirmed the formation of hydrogels. The higher the crosslinking density, the higher the storage modulus of hydrogels. CMCS- g -PLA hydrogels only slightly degrade in PBS for 10 days. In the presence of lysozyme, however, hydrogels with low crosslink density are totally degraded in 10 days. Drug release studies show that after 96 h, 95% of thymopentin is released under in vitro conditions. Copyright © 2015 John Wiley & Sons, Ltd.
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Materials Today Communications
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2021
·
IF 3.383
Thanakorn Yeamsuksawat,Hui Zhao,Jun Liang
This work aimed to synthesize Fe 3 O 4 @Chitosan@Ag nanoparticles by employing the suspension technique with a crosslinking agent, producing the Ag nanoparticles (AgNPs) using glucose as a reducing agent and applying them to the surface of Fe3O4@Chitosan. The Fe 3 O 4 @Chitosan@Ag nanoparticles were characterised by X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FTIR) to determine the existence of chitosan and Ag nanoparticles on the surface of the Fe 3 O 4 . The thermal stability, morphology, and magnetic behaviour were studied by comparing the results among Fe 3 O 4 , Fe 3 O 4 @Chitosan, and Fe 3 O 4 @Chitosan@Ag with thermogravimetric analyses (TGA), transmission electron microscopy (TEM), and a vibrating sample magnetometer (VSM), respectively. Moreover, the comparison of antimicrobial activity between Fe 3 O 4 @Chitosan and Fe 3 O 4 @Chitosan@Ag nanoparticles was conducted by the colony count method. Based on the results, both types of nanoparticles can inhibit the growth of microbes. However, the Fe 3 O 4 @Chitosan@Ag showed superior results of at least 99.5 % prevention of the growth of microorganisms. These developed antimicrobial nanoparticles could be the potential antimicrobial agent or additives in various medical, biological, food packaging, and textile applications.
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