ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2021
·Vol. 28
·期 13
·16754-16766
·
IF 4.223
Liu Si-Yu,Yu Wen-Jing,Wang Yi-Ru,Shao Xue-Ting,Wang De-Gao
Illicit drug use has long been a key issue of international concern, and the true situation is unknown to the relevant authorities. To develop a profile of comprehensive consumption patterns of illicit drugs in China, data from 34 wastewater treatment plants in 25 cities were collected to analyze four classes of drugs, including amphetamine-type stimulants, opioids, ketamine, and cocaine. They were identified and quantified in samples using methods based on gas chromatography coupled to mass spectrometry. According to the wastewater-based epidemiology (WBE) approach, an analysis of the consumption pattern was performed regarding per inhabitant consumption based on the revised metabolic rate. The consumption quantity of illicit drug and precursor was divided into four categories based on statistical difference analyses: methamphetamine and ephedrine (precursor) were the predominant drugs in the first category, followed by ketamine and heroin in the second category, methcathinone and 3,4-methylenedioxymethamphetamine (MDMA) in the third category, and cocaine and methadone in the fourth category. There were distinctive spatial patterns: heroin and cocaine consumption was higher in Southern China than in Northern China, heroin consumption was higher in Western China than in Eastern China, and the consumption of each drug differed across seven regions of China, especially with ephedrine and methcathinone consumption higher in North China; heroin consumption higher in Southwest, Central, and Northwest China; and ketamine and MDMA consumption higher in East, South, and Central China. Compared with findings in previous studies, there were temporal patterns, in which ketamine consumption presented a downward trend but heroin remained stable. Based on correlation analyses, there were the polydrug abuse patterns between heroin and cocaine, methcathinone and ketamine, and cocaine and MDMA. In general, this study based on WBE provides a comprehensive evaluation of drug consumption in China. Graphical abstract
研究领域:
公共卫生
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毒理学
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环境科学
✓ 已验证
DOI
高影响因子
ChemPlusChem
·
2013
·Vol. 79
·期 2
·211-216
·
IF 0
Wentao Hao,Songyan Ding,Liang Zhang,Wei Liu,Wen Yang
Graphical Mother-of-pearl films : Flexible, transparent, and glossy nanocomposite films have been fabricated through vacuum-aided filtration self-assembly of hyperbranched poly(amido amine)s (HPAMAMs) and clay nanosheets. Such hybrid films show strong fluorescence properties and high strength (see figure). As a result of the good biocompatibility of HPAMAMs, the hybrid films are promising in biomedical research. Inspired by the hierarchical structure of nacre, lots of functional nanocomposite films have been fabricated through finely tuning the composition and structure. To broaden their application in biological and biomedical research, it is highly demanded to develop a new strategy to fabricate nanocomposite films that are both biocompatible and functional. Herein, hyperbranched poly(amido amine)s (HPAMAMs) have been assembled with clay nanosheets. The obtained nanocomposite films show good mechanical performance and fluorescence properties. Analysis of the structure of the nanocomposite films indicates that the HPAMAMs and the clay nanosheets are stacked together in an orderly manner. The clay nanosheets align in the direction parallel to the film surface. Because of the inherent biocompatibility and autofluorescence property of the HPAMAMs, such composite films are thought to be very promising in applications requiring biocompatibility, fluorescence, and good mechanical performance. The method should provide a new route to the fabrication of functional nacrelike composite materials.
研究领域:
材料科学
·
生物医学
✓ 已验证
DOI
LANGMUIR
·
2020
·
IF 3.557
Yangguan Chen,Guorong Lin,Shuixia Chen
Amine-skeleton solid-amine materials are promising adsorbents for CO2 capture from flue gas. Here, a novel solid-amine microsphere was synthesized by cross-linking the skeleton poly(ethylenimine) (PEI) with ethylene glycol diglycidyl ether in a facile one-pot W/O emulsion system. The material had a remarkable CO2 adsorption capacity of 7.28 mmol/g in the presence of moisture at 20 °C, 0.1 bar. The highest ratio of breakthrough capacity to saturation capacity was ca. 84%. According to kinetic simulation, the Avrami kinetic model could better describe the adsorption process of CO2 under different temperatures, in which the value of R2 was above 0.99 and n was between 1 and 2, indicating that both physical and chemical adsorption mechanisms were performed during adsorption. Moreover, the material had a high swelling speed. Equilibrium was established within 30 s, and the swelling ratio was 271% at equilibrium. The saturated adsorbent could be easily regenerated with a regeneration efficiency of 94.63% after six cycles. The PEI microsphere appears to be a promising candidate material for CO2 capture from flue gas.
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2024
·
IF 4
Zahid Nawaz,Nevin Gürbüz,Muhammad Naveed Zafar,Muhammad Nawaz Tahir,İsmail Özdemir,Ryan J. Trovitch
A mild catalytic protocol for aldehyde, amine, and alkyne coupling (A 3 -coupling) allows for the selective synthesis of propargyl amines using 5,6-dimethylbenzimidazole-derived N-heterocyclic carbene (BNHC) silver(I) catalysts. A series of BNHC Ag(Ⅰ) halide complexes were synthesized and their structures have been elucidated through the use of multinuclear NMR and FT-IR spectroscopy. Furthermore, the pseudo-linear geometry of two different compounds was substantiated by single-crystal X-ray diffraction. Silver-based A 3 -coupling was achieved for both acyclic and cyclic secondary amines using a diverse set of alkynes to afford propargyl amines with yields of up to 95 %. The present approach is environmentally benign and water is generated as the sole byproduct.
研究领域:
有机化学
·
催化化学
✓ 已验证
DOI
高影响因子
NANOTECHNOLOGY
·
2020
·Vol. 31
·期 27
·275501
·
IF 3.551
Zhi Li,Weina Qian,Hui Guo,Ruyi Jin,Jiang Taoliu,Jianbin Zheng
In this study, amorphous cobalt hydroxide/polyaniline nanofibers (Co(OH)2/PANINF) composites were successfully prepared. The formation of amorphous Co(OH)2 with irregular surface structure was confirmed by x-ray diffraction, scanning electron microscopy, and selected-area electron diffraction. The non-enzymatic electrochemical sensor for the selective and sensitive determination of dopamine (DA) has been constructed by using Co(OH)2/PANINF composites modified glassy carbon electrode (Co(OH)2/PANINF/GCE), which exhibited excellent electrocatalytic activity toward DA, in a large part owing to the advantages of large surface area of amorphous Co(OH)2 and the synergetic effect between Co(OH)2 and PANINF. The electrochemical kinetics reveal that the DA oxidation involves two electrons and two protons in a quasi-reversible electrode reaction. Differential pulse voltammetry (DPV) studies show remarkable sensing performance for the determination of DA, with a low detection limit of 0.03 μM, and a wide linear range from 0.1 to 200 μM. From a broader perspective, the present study demonstrates that Co(OH)2/PANINF composites would be promising supporting materials for novel sensing platforms.
研究领域:
材料科学
·
分析化学
✓ 已验证
DOI
高影响因子
MACROMOLECULES
·
2015
·
IF 5.8
Ze Zhang,Ye-Zi You,De-Cheng Wu,Chun-Yan Hong
Multicomponent reactions have recently attracted a great deal of attention as they are considered as a powerful tool for constructing sequence-controlled polymers. Although new examples are constantly flourishing in the literature, the process that allows two or more consecutive multicomponent-reactions to react in a single operation for the syntheses of sequence-controlled polymers has not been developed until now. Here, we propose a new strategy combining multicomponent reaction of amine, thiol, and alkene conjugating and multicomponent polymerization of diyne, azide, and diamine coupling in one-pot for the synthesis of sequence-controlled polymer.
研究领域:
高分子化学
·
有机合成
✓ 已验证
DOI
高影响因子
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
·
2013
·
IF 1.333
Lin Gu,Zheng hong Wu,Xiaole Qi,Huan He,Xiaoli Ma,Xiaohua Chou,Xiaoguang Wen,Miao Zhang,Fang Jiao
The potential of polyamidoamine (PAMAM) dendrimers as solubility enhancers and oral drug delivery system was well known. Herein, we investigated the possibility of PAMAM dendrimers for promoting the solubility and oral bioavailability of puerarin. In the present study, the effect of PAMAM dendrimers with different generations (G1.5, G2, G2.5, and G3) on the solubility of puerarin was evaluated at different concentrations and pH conditions. Further more, the puerarin–G2 dendrimer complex was conducted for the in vitro hemolytic toxicity studies and pharmacokinetics studies in rats. The solubility of puerarin was significantly higher in the presence of the full generation dendrimers (e.g. G2 and G3). No significant hemolysis was observed on erythrocytes (G2, 0–2.5 mg/mL) in the hemolytic toxicity studies. The pharmacokinetics parameters Tmax, Cmax, and AUC0–8 h of puerarin suspension solution and puerarin–G2 dendrimer complex solution were 0.76 h, 1.50 µg/mL, 7.33 µg·h/mL and 0.33 h, 6.49 µg/mL, 14.02 µg·h/mL, respectively. These studies demonstrate that PAMAM dendrimers may be a promising strategy for peroral delivery of puerarin.
研究领域:
药剂学
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药物递送系统
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生物医学工程
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL PHYSICS LETTERS
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2020
·
IF 2.029
Yuyu Guo,Shuxuan Shi,Chunyan Fan,Dan Jin
The polyethyleneimine-capped copper nanoclusters (PEI-Cu NCs) were prepared by using polyethyleneimine as protective agent and hydrazine hydrate as reducing agent. The PEI-Cu NCs possessed strong fluorescence intensity, excellent water solubility, good stability and high dispersion. The sample’s fluorescence could be selectively quenched by the addition of fluazinam. There was a good linear relationship between the relative fluorescence intensity of PEI-Cu NCs and concentrations of fluazinam in the range of 0.5–70 μM. The quenching mechanism might be dynamic quenching and inner filter effect (IFE). Significantly, the PEI-Cu NCs could be used to detect fluazinam as fluorescent probe in environmental water samples.
研究领域:
分析化学
·
环境科学
✓ 已验证
DOI
高影响因子
CRYSTAL GROWTH & DESIGN
·
2021
·
IF 4.076
Yunping Zhoujin,Xing Yang,Mingtao Zhang,Ju Guo,Sean Parkin,Tonglei Li,Faquan Yu,Sihui Long
A lactam–lactam dimer (LLD) and lactam NH···O═C (amide) catemer (LAC) are two competing motifs in N-phenyl-2-hydroxynicotinanilides (PHNAs). Steric effects play an important role in determining the outcome of this competition, and in general, PHNAs with no or negligible steric hindrance take on a near-planar conformation and form LLDs, rather than the widely observed amide NH···O═C hydrogen-bond chains. Conversely, those with significant steric hindrance are forced to take on a twisted conformation and form a lactam NH···O═C (amide) hydrogen bond. Nevertheless, steric factors are not the only criteria, as an LLD and an LAC have been observed in the two polymorphs (1-I and 1-II) of 2-hydroxy-N-m-tolyl-nicotinamide (namely 2-oxo-1,2-dihydropyridine-3-carboxylic acid m-tolylamide, compound 1), although the molecules in both forms have a nearly identical conformation, in contrast to five other newly synthesized PHNAs (2–6), whose crystal structures are sustained on the LLD. Thus, synthon polymorphism is possible in conformationally planar PHNAs. Theoretical studies were performed to provide an explanation for this observation. The lattice energies of the two forms of 1 showed only an insignificant difference. A Hirshfeld analysis revealed that the loss of stability due to less hydrogen bonding in 1-II is compensated by the participation of π–π stacking. Other than the commonly observed LLD in the crystals, π–π stacking provides a significant stabilization for each crystal, with its particular effects being dependent on the substitution pattern of the compound. A noncovalent interaction (NCI) analysis further provided a visual demonstration of the important intermolecular interactions. Potentially the other planar compounds could behave in a similar manner.
研究领域:
晶体学
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理论化学
·
材料科学
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2016
·
IF 7.145
Jiayun Fan,Xingmao Chang,Meixia He,Congdi Shang,Gang Wang,Shiwei Yin,Haonan Peng,Yu Fang
Modification of naphthalene diimide (NDI) resulted in a photochemically stable, fluorescent 3,4,5-tris(dodecyloxy)benzamide derivative of NDI (TDBNDI), and introduction of the long alkyl chains endowed the compound with good compatibility with commonly found organic solvents and in particular superior self-assembly in the solution state. Further studies revealed that TDBNDI forms gels with nine of the 18 solvents tested at a concentration of 2.0% (w/v), and the critical gelation concentrations of five of the eight gels are lower than 1.0% (w/v), indicating the high efficiency of the compound as a low-molecular mass gelator (LMMG). Transmission electron microscopy, scanning electron microscopy, and confocal laser scanning microscopy studies revealed the networked fibrillar structure of the TDBNDI/methylcyclohexane (MCH) gel. On the basis of these findings, a fluorescent film was developed via simple spin-coating of the TDBNDI/MCH gel on a glass substrate surface. Fluorescence behavior and sensing performance studies demonstrated that this film is photochemically stable, and sensitive and selective to the presence of aniline vapor. Notably, the response is instantaneous, and the sensing process is fully and quickly reversible. This case study demonstrates that derivatization of photochemically stable fluorophores into LMMGs is a good strategy for developing high-performance fluorescent sensing films.
研究领域:
材料化学
·
分析化学
✓ 已验证
DOI
高影响因子
Heliyon
·
2020
·
IF 0
Reza Assefi Pour,Robabeh Bagheri,Tayyab Naveed,Nadir Ali,Faisal Rehman,Jinxin He
Recently, natural dyes have a widening scope in various traditional and advanced applications due to their eco-friendly environment. However, improved dyeability of natural dyes still remains a challenging task. This research was aimed to achieve multi-objective wool with improved dyeability using bio-nano-mordant composed of m-Trans-glutaminase, m-TGase, and bentonite nanoclay. Wool fiber was treated through sonochemical method using different concentrations of m-TGase and bentonite. The surface morphology of wool fabric samples was examined by field emission-scanning electron microscopy (FESEM), and Fourier transform Infrared Radiation (FTIR). Further, wool samples treated at different conditions were applied to madder for dyeability examination. The optimum conditions of color coordinates, color strength, K/S, and washing fastness of madder on treated wool fabric with m-TGase and bentonite, were also examined. The results revealed well-made interactions among m-TGase, bentonite, and wool fibers. In addition, surface morphology was strongly influenced by variations in enzyme concentrations so that extra addition of m-TGase lead to clear damage scales or less cuticle surface in SEM images. Moreover, the results showed that the value of K/S for treated wool samples was better than untreated samples. Indeed, amongst all, 5% concentrations of bio-nano-mordant for m-TGase and bentonite have the most constructive K/S values. Similarly, results of Δ E and antibacterial investigations also confirmed its superiority.
研究领域:
纺织科学
·
生物技术
·
材料科学
✓ 已验证
DOI
PubMed
Journal of Physical Chemistry C
·
2018
·
IF 4.484
Hao Wang,Huili Ye,Bihong Zhang,Faqiong Zhao,Baizhao Zeng
A ZnIn2S4/CdS photocatalyst was synthesized based on an electrostatic interaction mechanism and was used to construct a photoelectrochemical (PEC) sensor for the highly sensitive and selective detection of dopamine (DA). As CdS and ZnIn2S4 possessed overlapping band potentials, they could form a heterojunction, which was favorable for charge separation and PEC conversion. Thus, the ZnIn2S4/CdS composite showed better PEC properties and higher photocatalytic activity than pure ZnIn2S4 and CdS. When it was used for DA sensing in a weak alkaline solution, DA turned to polydopamine and acted as an effective electron acceptor to make the anodic photocurrent decrease. Owing to adopting this detection strategy, the interference of coexistent reductive species (i.e., electron donor) was avoided effectively. Under the optimized conditions, the photocurrent change was linear to DA concentration in the range from 0.3 to 300 μM, and the detection limit was 0.1 μM. The ZnIn2S4/CdS/indium tin oxide sensor was applied for the indirect detection of DA in urine samples, and it presented a good performance.
研究领域:
材料科学
·
分析化学
·
生物医学工程
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）