Biochemistry and Cell Biology
·
2024
·
IF 2.4
Wei Yan,Ruolan Wu,Yingying Lee,Liqun Xu,Xiao Li,Junwei Li,Ronghao Deng,Xing Fan,Yilang Wu,Haibao Zhu,Aihua Mao,Jianxin Shen,Chi-ju Wei
Enucleated cells, also known as cytoplasts, are valuable tools with a wide range of applications. However, their potential for bio-engineering is greatly restricted by the short lifespan. We postulated that the enucleation process damages the integrity of the plasma membrane and thus activates a cell death program(s). The results showed that a tiny hole was generated transiently on the plasma membrane when the nucleus was spun off, while force-gated ion channels were activated in response to the pulling by the nucleus. Influx of extracellular calcium stimulated the opening of calcium channels and the release of calcium from endoplasmic reticulum and mitochondria. Long lasting calcium transient increased protein phosphorylation and activated caspase 9 and calpain proteinase activities. Subsequently, mitochondria membrane permeability and Reactive Oxygen Species (ROS) levels were significantly elevated, which eventually led to eryptosis-like cell death. When extracellular calcium was maintained at optimal concentration, the lifespan of enucleated cells was extended; however, huge amounts of vacuoles appeared in the cytoplasm, possibly derived from enlarged autophagosomes. Inhibition of vacuolation by inhibitors of autophagy or in co-culture with primary muscle cells did not rescue cells dying from the paraptosis-like pathway. These results offer valuable insights for further investigation into the intricate mechanisms underlying enucleated cell death.
研究领域:
细胞生物学
·
干细胞研究
·
分子生物学
·
钙信号传导
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Fangfang Huang,Fengzhen Lv,Danruoyu Wang,Yuan Gao,Tao Wang,Jun Liu,Xuedong Tian,Fuchi Liu,Lizhen Long
A series of (CH3NH 3 ) 2- x Cs x AgBiBr 6 films ( x =0, 0.1, 0.2, 0.3, 0.4) were fabricated on ITO/glass substrates through the sol-gel method. 15 % Cs doping ( x =0.3) was the optimal condition for enhancing the film quality and achieving nonvolatile bipolar resistive switching (BRS) performance in the devices. The on/off ratio in the (CH 3 NH 3 ) 1.7 Cs 0.3 AgBiBr 6 (Cs-MAABB-3)-based RS device reached 7.7×10 4 , high and low resistance states were maintained for over 10 4 s. Under different light intensities with a wavelength of 430 nm, six distinct resistance states were recorded at −0.3 V in the Au/Cs-MAABB-3/ITO/glass device. These multilevel states remained after 5000 s and 650 cycles, indicating the excellent retention and endurance of multilevel RS memory in the Au/Cs-MAABB-3/ITO/glass device. The RS behavior in this device followed the trap-controlled space charge-limited current and conductive filament models. Cs-doping increased the concentration of intrinsic vacancies appropriately, leading to a more prominent RS effect. With varying intensities of illumination, the change of Schottky-like barrier at the Au/Cs-MAABB-3 interface, modulated by the photo-induced carriers, affected the multilevel resistance states in the device. The excellent multilevel RS performance was observed for the first time in the Cs-MAABB-3-based device. It presents broad possibilities for improving high-density memory in lead-free halide double perovskite-based devices.
研究领域:
材料科学
·
电子工程
✓ 已验证
DOI
高影响因子
Nano-Micro Letters
·
2021
·Vol. 14
·期 1
·1-12
·
IF 16.419
Zhu Mengya,Li Guangyong,Gong Wenbin,Yan Lifeng,Zhang Xuetong
A calcium-doped boron nitride (Ca-BN) aerogel was synthesized by introducing Ca into crystal structure of BN building blocks.
The aerogels exhibited superior high-temperature stability and could resist the burning of butane flame (~1300 °C) in air atmosphere.
Ca-BN aerogel, together with Al foil, can effectively hide thermal target at high temperature up to 1300 °C.
研究领域:
材料科学
·
热学工程
✓ 已验证
DOI
高影响因子
Advanced Powder Materials
·
2022
·
IF 0
Siqi Zhan,Wenhe Ding,Zhongliang Sun,Wei Li,Tiening Xu,Shiwei Wang,Mingyao Zhang
How to improve the stability and processability of organic-inorganic hybrid perovskite quantum dots (OHPQD) is an important topic in recent research. In this work, the stability and machinability of OHPQD were improved by blending with PU elastomer. The CsPbBr 3 −PU composites can be achieved easily by pouring molding process with rather excellent humidity and thermal stability. The tensile strength of 14 MPa and elongation of 580% at break of PU/CsPbBr 3 elastomer composites with self-repair properties were obtained, which was attributed to the introduction of disulfide bonds. It lays a foundation for the application of OHPQD.
研究领域:
材料科学
·
纳米技术
✓ 已验证
DOI
BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA
·
2024
·Vol. 38
·期 5
·1251-1260
·
IF 1.3
Da-Chuan Ge,Wen Zhu,Yu-Xuan Li,Feng Zhang,Yun Chen,Jian-Hua Sun,Zhao-Xi Wang
Perovskite-like compounds have attracted great attention because of their good properties, such as electrical, optical, and magnetic properties, etc. Herein, a new perovskite-like anionic dicyanamidometallate, namely (Bu3MeP)[Ni(dca)3] (1) (Bu3MeP = tributylmethylphosphine cation, dca = dicyanamide), was synthesized and structurally characterized by elemental analysis, IR spectrum, thermogravimetric analysis, and single-crystal X-ray diffraction. The compound crystallizes in the tetragonal crystal system with the chiral space group P43212, and exhibits a three-dimensional anionic dicyanamidometallate framework from Ni2+ units bridged by dicyanamides, in which tributylmethylphosphine cations are accommodated in the voids. The butyl groups present two conformations in the tributylmethylphosphine cation, resulting in chirality character occurred in compound 1. Variable-temperature magnetic susceptibility analysis indicates that weak ferromagnetic interaction exists between the nickel(II) ions coupling by μ1,5-bridings.
KEY WORDS: Perovskite-like, Dicyanamidometallate, Crystal structure, Magnetic properties
Bull. Chem. Soc. Ethiop. 2024, 38(5), 1251-1260.
DOI: https://dx.doi.org/10.4314/bcse.v38i5.5
研究领域:
材料科学
·
化学
✓ 已验证
DOI
高影响因子
Chinese Optics Letters
·
2021
·Vol. 19
·期 2
·021601
·
IF 2.448
Jing Zhu,Shiqing Xu,Lei Lei,Feifei Huang,Zhen Xiao
Up-convertion (UC) perovskite Er3+-doped PbTiO3 (Er-PTO) nanoparticles with green and red emissions were synthesized via the hydrothermal method. The UC properties were manipulated by adjusting the concentration of Er3+ ions dopant. The green emission intensity was decreased as the doping concentration increased from 1% to 4% (mole fraction), whereas the red emission intensity was increased. The influences of Er3+ ions on the temperature-sensing performance were further investigated. The results demonstrated that Er-PTO nanoparticles with doping 1% Er3+ ions possessed a sensitivity of 3.1 × 10-3 K−1 at 475 K, presenting a high potential in optical heating devices.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
高影响因子
LANGMUIR
·
2021
·
IF 3.882
Sai-Nan Guo,Hao Wu,Dan Wang,Jie-Xin Wang
Lead halide perovskite quantum dots (QDs) are known as prospective optoelectronic device materials because of their excellent luminescence, extraordinary photoelectric performance, and specific octahedron framework. Herein, we report a cost-effective approach for synthesizing highly stable CH3NH3PbBr3 QDs in low-polarity binary solvents without nitrogen protection. The CH3NH3PbBr3 QDs are tunable from 1.2 to 4.2 nm by adjusting the proportion of oleic acid and oleylamine as capping ligands. The photoluminescence quantum yield of CH3NH3PbBr3 QDs can reach 87.4%. The fluorescence can maintain over 80% of its earliest emission intensity under the atmosphere after 5 days, which is much better than that (∼10%) of QDs with ligand-assisted reprecipitation. The possible reaction mechanism of preparing CH3NH3PbBr3 QDs was also addressed. Notably, such a strategy can be applied extensively in the preparation of other lead halide perovskite QDs. Furthermore, the as-prepared thick PMMA-coated CH3NH3PbBr3 QDs were further conjoined with a red luminescence powder on a blue InGaN chip to obtain a powerful efficiency (45.4 lm W–1) warm white light-emitting diode.
研究领域:
材料科学
·
光学工程
·
化学
✓ 已验证
DOI
高影响因子
Cell Reports
·
2019
·
IF 7.815
Peilin Yu,Zhenming Liu,Xiafei Yu,Peiwu Ye,Huan Liu,Xiwen Xue,Lixin Yang,Zhongtang Li,Yang Wu,Cheng Fang,Yong Juan Zhao,Fan Yang,Jian Hong Luo,Lin-Hua Jiang,Liangren Zhang,Lihe Zhang,Wei Yang
Summary cADPR is a well-recognized signaling molecule by modulating the RyRs, but considerable debate exists regarding whether cADPR can bind to and gate the TRPM2 channel, which mediates oxidative stress signaling in diverse physiological and pathological processes. Here, we show that purified cADPR evoked TRPM2 channel currents in both whole-cell and cell-free single-channel recordings and specific binding of cADPR to the purified NUDT9-H domain of TRPM2 by surface plasmon resonance. Furthermore, by combining computational modeling with electrophysiological recordings, we show that the TRPM2 channels carrying point mutations at H1346, T1347, L1379, S1391, E1409, and L1484 possess distinct sensitivity profiles for ADPR and cADPR. These results clearly indicate cADPR is a bona fide activator at the TRPM2 channel and clearly delineate the structural basis for cADPR binding, which not only lead to a better understanding in the gating mechanism of TRPM2 channel but also shed light on a cADPR-induced RyRs-independent Ca 2+ signaling mechanism.
研究领域:
细胞生物学
·
分子生物学
·
生理学
✓ 已验证
DOI
高影响因子
Device
·
2025
·
IF 8
Hao Wang,Wenjia Zhou,Yunlong Liu,Haobo Wu,Si Peng,Wei Xuan Liu,Ruiqi Xu,Wei Zhou,Mingyu Ma,Gaoqi Liu,Juan Du,Yuxin Leng,Zhiqun Lin,Wei Lu,Zhijun Ning
An upconversion device uses a methodology for direct infrared imaging, but the performance is limited by the inefficient carrier transmission between infrared detecting and emitting layers. Herein, we developed an upconversion infrared imaging device by integrating infrared quantum dots and a perovskite quantum well emitter. The energy level of the perovskite quantum well aligns well with the infrared quantum dot, leading to an effective carrier transition between them, generating a photon conversion efficiency of over 10% and a high on-off ratio of 45.5. The device shows a resolution of 11 μm, 3-fold higher than the best value achieved for solution-processed infrared upconversion devices. Furthermore, based on solution-phase ligand exchange, a large-area homogeneous 3 × 3 cm upconversion device is fabricated. The large-area device shows an estimated pixel scale of over 7 million pixels, enabling it to be used for direct infrared visualization.
研究领域:
光学工程
·
材料科学
·
电子工程
✓ 已验证
DOI
高影响因子
Journal of Physical Chemistry C
·
2019
·
IF 4.309
Weizheng Wang,Yumeng Zhang,Wenhui Wu,Xiaoyu Liu,Xuanxuan Ma,Guixiang Qian,Jiyang Fan
The organic–inorganic hybrid metal halide perovskites with different dimensions and diverse architectures are highly attractive materials for optoelectronic applications. However, people know little about the dynamics of their formation processes. Here, we study both experimentally and theoretically the self-assembly formation dynamics of the luminescent colloidal CH3NH3PbBr3 nanocrystals. We have observed their successive transformations from original spherical quantum dots to periodically stacked nanoplatelets when the primitive colloidal nanocrystals with a high concentration were maintained in liquid for a prolonged period of time. A theoretical dynamic collision model by taking into account the popular van der Waals force, the polarization force that is unique for the perovskites, and the electrostatic forces between particle surfaces in the presence of the surface ligands is proposed to explain the self-assembly process of the colloidal CH3NH3PbBr3 nanocrystals. The result reveals that the rather easy self-assembly of the organic–inorganic hybrid perovskites with different morphologies in the absence of enough surface ligands is closely related to their intrinsic polarization force, whereas the presence of the surface ligands could hamper the self-assembly process. The proposed theoretical model is general and can be used to analyze the self-assembly dynamics of various types of colloidal nanostructures.
研究领域:
材料科学
·
光学
·
化学动力学
✓ 已验证
DOI
高影响因子
MATERIALS RESEARCH BULLETIN
·
2021
·
IF 4.641
Jidong Deng,Jiao Xun,Wei Shen,Ming Li,Rongxing He
Although lead halide perovskite nanocrystals (PNCs) materials exhibit excellent optoelectronic properties, their instability and toxicity seriously limit their wide-spread application. Herein, we described a new type of highly-luminescent Sb 3+ -doped dual-phase CsPb 2 Br 5 /CsPbBr 3 PNCs material, synthesized by a modified ligand-assisted re-precipitation (LARP) method at room temperature. The obtained Sb 3+ -doped dual-phase PNCs achieve high photoluminescence quantum yields (PLQYs) and excellent light, water, and thermal stability. Additionally, the fast anion exchange involving Sb 3+ -doped dual-phase PNCs effectively extends their photoluminescence across the entire visible spectral region. The large-scale synthesis and optical tunability of low-toxicity Sb 3+ -doped dual-phase CsPb 2 Br 5 /CsPbBr 3 PNCs are advantageous for future applications in optoelectronic devices.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2018
·
IF 3.927
Ping Tang,Wenchao Jiang,Shuguang Lyu,Zhaofu Qiu,Qian Sui
The degradation of carbon tetrachloride (CT) by Fe(II) activated calcium peroxide (CaO 2 ) in the presence of ethanol (CH 3 CH 2 OH, EtOH) was investigated. The results showed that CT could be completely degraded in 20 min with 3.90 mmol L −1 CaO 2 , 5.20 mmol L −1 Fe(II) and 1.30 mmol L −1 EtOH in CaO 2 /Fe(II)/EtOH system. Superoxide radical anion (O 2 •− ) and hydroxyethyl radical ( • CHCH 3 OH, HER) were demonstrated as the main radicals for CT degradation which were confirmed by scavenging tests and electron paramagnetic resonance (EPR) detection. The mechanism of CT degradation was mainly due to the split of C–Cl and CT degradation pathway was proposed accordingly. Further investigation suggested that the solution pH in range of 3–5 were favorable to CT degradation. Both Cl − and HCO 3 − had inhibitive effect on CT removal, while the influence of NO 3 − and SO 4 2− could be negligible. Moreover, the results of experiments performed using actual groundwater demonstrated that an adverse impact occurred on CT degradation, but this drawback could be overcome by increasing reagent dosages. In summary, CT degradation in Fe(II) activated CaO 2 system can be significantly promoted by EtOH addition, and this finding, for the first time, provides an innovative technology for degradation of the highly oxidized organic contaminants.
研究领域:
环境科学
·
化学
✓ 已验证
DOI
高影响因子
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