JOURNAL OF ALLOYS AND COMPOUNDS
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2024
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IF 5.8
Xinrong Zhong,Anze Shui,Hulei Yu,Yawei Fang
The remarkable polarization and stability of ceramic capacitors make them promising candidates for pulse-power devices in energy-storage systems. However, the energy-storage density of ceramic capacitors is severely limited by the negative correlation between the maximum polarization ( P m ) and the breakdown strength (BDS), leading to the impediment of broader applications. Herein, we reconcile the contradiction by synthesizing high-performance NaNbO 3 -based ceramics via chemical doping with Bi(Ni 0.5 Ti 0.25 Zr 0.25 )O 3 (BNTZ). An antiferroelectric-paraelectric phase transition with a decline in polarization hysteresis is induced by the dopant. Further studies have shown that the existence of a tiny quantity of the polar phase in the nonpolar matrix contributes to a higher P m , and the enhancement of both electrical resistivity and activation energy of the conductance also improved their BDS. The thinning process is also identified to be important in the improvement of its BDS and W rec , resulting in the maximum energy-storage density of 3.53 J/cm 3 with an energy efficiency of 74.2 % in thinned 10 mol% BNTZ-doped NaNbO 3 samples. Our findings provide a feasible approach to simultaneously improving energy-storage density and efficiency in NaNbO 3 -based ceramic capacitors.
研究领域:
材料科学
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电气工程
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能源存储
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2023
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IF 15.1
Hang Xu,Anqi Niu,Zihan Shang,Geng Li,Fengmin Wu,Xuefeng Wei,Jun Zhang
A heterogeneous catalyst was prepared by wrapping a poly 3-butyl vinylimidazole cobalt chloride ionic liquid (P[BVIM]CoCl 3 ) around the surface of Fe 3 O 4 @SiO 2 magnetic nanoballs. This catalyst was coupled with the oxidant peroxymonosulfate (PMS) for extraction catalytic oxidation desulfurization (ECODS). The prepared desulfurization catalyst had superparamagnetic properties, with a saturation magnetization of 32.5 emu/g. Moreover, this caalyst was multi-porous material, ans it had a specific surface area and pore volume of 8.14 m 2 /g and 0.018 cc/g, respectively. The average pore diameter of catalyst was 3.9 nm. The optimal experimental conditions were as follows: the initial sulfur content of the oil was 500 ppm, the catalyst dosage was 30 mg, PMS (20 wt%) dosage was 0.6 g, the ACN dosage was 2 g, and the oil sample size was 6 g. After 20 min, a sulfur removal rate of over 98 % was achieved at 20 °C. Furthermore, the unpurified catalyst still maintained high desulfurization activity after being used for 5 times, demonstrating good stability. The desulfurization mechanism was divided into two steps: first, DBT was oxidized to DBTO by SO 4 − free radicals, and second, the DBTO was further oxidized to DBTO 2 by OH free radicals in a tandem reaction. The reaction rates for the two steps at 20 °C were 0.0144 sec −1 and 0.00115 sec −1 , respectively. The activation energies associated with these steps were 65.65 kJ/mol and 105.22 kJ/mol, respectively. The quencher t-butanol had no effect on the first step but significantly inhibited the second step, meaning that DBTO became the main oxidation product. One potential application of this study is the utilization of t-butanol to regulate the oxygen content in organic sulfide oxidation products.
研究领域:
催化
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环境化学
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材料科学
✓ 已验证
DOI
高影响因子
Redox Biology
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2024
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IF 10.7
Bi-Xin Xu,Tian-Yu Hu,Jin-Biao Du,Tao Xie,Ya-Wen Xu,Xin Jin,Si-Tao Xu,Hao-Wen Jin,Guangji Wang,Jiankun Wang,Le Zhen
Redox-responsive hydropersulfide prodrugs are designed to enable a more controllable and efficient hydropersulfide (RSSH) supply and to thoroughly explore their biological and therapeutic applications in oxidative damage. To obtain novel activation patterns triggered by redox signaling, we focused on NAD(P)H: quinone acceptor oxidoreductase 1 (NQO1), a canonical antioxidant enzyme, and designed NQO1-activated RSSH prodrugs. We also performed a head-to-head comparison of two mainstream structural scaffolds with solid quantitative analysis of prodrugs, RSSH, and metabolic by-products by LC-MS/MS, confirming that the perthiocarbamate scaffold was more effective in intracellular prodrug uptake and RSSH production. The prodrug was highly potent in oxidative stress management against cisplatin-induced nephrotoxicity. Strikingly, this prodrug possessed potential feedback activation properties by which the delivered RSSH can further escalate the prodrug activation via NQO1 upregulation. Our strategy pushed RSSH prodrugs one step further in the pursuit of efficient release in biological matrices and improved druggability against oxidative stress.
研究领域:
药学
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生物化学
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分子生物学
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毒理学
✓ 已验证
DOI
PubMed
高影响因子
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
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2024
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IF 2.7
Li-Hong Liu,Yu-Feng Liu,Hong-Bo Zhang,Xiao-Lei Liu,Han-Wen Zhang,Biao Huang,Fan Lin,Wei-Hua Li
PurposeDevelop an albumin nanoparticle-based nanoprobe for targeted glioblastoma (GBM) diagnosis and treatment, utilizing Angopep-2 for low-density lipoprotein receptor-related protein (LRP) targeting.MethodsCombined albumin-coated superparamagnetic iron oxide (SPIO), Carmustine (BCNU), and indocyanine green (ICG). Assessed morphology, size, Zeta potential, fluorescence, and drug encapsulation. Conducted in vitro fluorescence/MRI imaging and cell viability assays, and in vivo nanoprobe accumulation evaluation in brain tumors.ResultsANG-BSA/BCNU/ICG MNPs exhibited superior targeting and cytotoxicity against GBM cells in vitro. In vivo, enhanced brain tumor accumulation during imaging was observed.ConclusionThis targeted imaging and drug delivery system holds promise for efficient GBM therapy and intraoperative localization, addressing Blood-brain barrier (BBB) limitations with precise drug delivery and imaging capabilities.
研究领域:
纳米技术
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神经肿瘤学
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药物递送系统
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医学成像
✓ 已验证
DOI
PubMed
高影响因子
Journal of Physical Chemistry Letters
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2021
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IF 6.475
Li Liu,Keliang Pan,Ke Xu,Xitian Peng,Jin Z. Zhang
Mn2+-doped amino lead halide molecular clusters (MCs) are synthesized using amine (e.g., n-octylamine, or butylamine) as passivating ligand and MnX2 (X = Cl or Br) as the Mn2+ doping source at room temperature. Their optical properties are investigated with UV–visible absorption, photoluminescence (PL), and PL excitation spectroscopy. The Mn2+ precursor plays a vital role in the synthesis of Mn2+-doped MCs. MnCl2 seems to facilitate the incorporation of Mn. The MnCl2 doping causes electronic absorption blue shift and leads to a spin-forbidden 4T1 → 6A1 Mn d-electron emission. With the help of time-resolved PL, Fourier transform infrared, and electron paramagnetic resonance results, a model is proposed to explain the formation mechanism. We suggest that Mn2+ doping replaces Pb2+ is assisted by Cl– ions that replace Br– ions. This study demonstrates the possibility of doping MCs and has important implications in gaining new fundamental insight into the growth mechanisms of perovskite nanostructures.
研究领域:
材料科学
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无机化学
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光学光谱学
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纳米技术
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凝聚态物理
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2019
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IF 8.355
Xinyu Du,Xue Bai,Lu Xu,Lei Yang,Pengkang Jin
A novel TiO 2 /g-C 3 N 4 -PS system was proposed, in which a TiO 2 /g-C 3 N 4 heterojunction was used to activate persulfate (PS) to enhance pollutant photodegradation under visible-light irradiation. In this study, the TiO 2 /g-C 3 N 4 photocatalyst was synthesized by a simple calcination method, and acetaminophen (AAP) was chosen as a model pollutant to test the degradation efficiency of the photocatalytic system. The TiO 2 /g-C 3 N 4 -PS system exhibits an efficient activity for PS activation and a high efficiency for pollutant degradation . The results show that 100 mL of a 5 mg/L AAP solution could be almost completely degraded in 30 min with 0.5 g/L photocatalyst and 2 mM PS, and TOC can be decreased by 82.5% in 60 min. After adding PS, the degradation rate of the TiO 2 /g-C 3 N 4 photocatalytic system was greatly improved by nearly 13 times, compared to the TiO 2 /g-C 3 N 4 system. The radical quenching experiments and electron paramagnetic resonance (EPR) results indicate that SO 4 − , OH and h + all contribute to eliminating organic compounds. Additionally, the TiO 2 /g-C 3 N 4 -PS photocatalytic system was employed to eliminate other typical micropollutants, such as phenol , bisphenol A and carbamazepine, and experiments were also carried out using real water matrices, and the ideal performance shows that the TiO 2 /g-C 3 N 4 -PS photocatalytic system has a strong nonselective oxidative ability for degrading contaminants.
研究领域:
环境科学
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化学
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材料科学
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水处理
✓ 已验证
DOI
高影响因子
JOURNAL OF ENVIRONMENTAL RADIOACTIVITY
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2018
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IF 2.263
Maoyi Luo,Shan Xing,Yonggang Yang,Lijuan Song,Yan Ma,Yadong Wang,Xiongxin Dai,Steffen Happel
There is a growing demand for the determination of actinides in soil and sediment samples for environmental monitoring and tracing, radiological protection, and nuclear forensic reasons. A total sample dissolution method based on lithium metaborate fusion, followed by sequential column chromatography separation, was developed for simultaneous determination of Pu, Am and Cm isotopes in large-size environmental samples by alpha spectrometry and mass spectrometric techniques. The overall recoveries of both Pu and Am for the entire procedure were higher than 70% for large-size soil samples. The method was validated using 20 g of soil samples spiked with known amounts of 239 Pu and 241 Am as well as the certified reference materials IAEA-384 (Fangataufa Lagoon sediment) and IAEA-385 (Irish Sea sediment). All the measured results agreed very well with the expected values.
研究领域:
环境科学
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核化学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
Journal of Macromolecular Science Part A-Pure and Applied Chemistry
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2024
·
IF 2.1
Yi Teng,Shu Wu,Xia Chen,Lu Bai,Qiuhua Wu,Guolin Zhang
New magnetic yolk-shell mesoporous silica nanoparticles (Fe3O4@V-mSiO2-PNVCL) were prepared by grafting temperature-sensitive amino-terminated poly (N-vinylcaprolactam) (PNVCL-NH2) on the surface of aldehyde-functionalized magnetic mesoporous silica nanoparticles (Fe3O4@V-mSiO2-CHO) through a Schiff base reaction. Various characterizations were used to confirm the structures, and the drug loading and release behaviors were studied. The drug loading was achieved as PNVCL stretched at room temperature and the drug loading content was up to 54.7% due to the large cavities. The encapsulation of drug from leakage in the blood environment was realized as PNVCL collapsed at physiological temperature. The fracture of pH-liable imine bonds in a slightly acidic tumor environment triggered the burst release of cargo. The Fe3O4@V-mSiO2-PNVCL showed super paramagnetic behavior (21.01 emu∙g−1) which could achieve magnetic targeting. The MTT assay confirmed that the nanoparticles exhibited low cytotoxicity. Furthermore, the cellular uptake experiments indicated that DOX-loaded nanoparticles were successfully internalized into cancer cells. Therefore, the composite nanoparticles are ideal choices for drug carriers.
研究领域:
纳米技术
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药物输送系统
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生物医学工程
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材料科学
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生物化学
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2021
·
IF 6.707
Limeng Yang,Wendou Chen,Cuihong Sheng,Hailiang Wu,Ningtao Mao,Hui Zhang
Peroxymonosulfate (PMS)-based advanced oxidation processes (AOPs) are encouraging methods for wastewater treatments, but the recycling of used PMS activators in powder form from the wastewater treatment system is still problematic. In this paper, we designed a novel and highly effective carbocatalyst for PMS activation, which was achieved by pyrolyzing the hybrids of metal–organic framework MIL-101(Fe) and dicyandiamide immobilized on the surface of carbon cloth (CC), and a facile route for the preparation of fibrous catalysts was developed. The resultant CC loaded with Fe/N-codoped carbocatalyst exhibited desirable reusability and good stability for the degradation of organic dyes. The mechanism of the novel Fe/N-codoped carbocatalyst for PMS activation including the specific roles of N species and Fe-N binding was investigated. It was demonstrated in electrochemical impedance spectroscopy (EIS) results that the CC facilitated the electron transport of the carbocatalyst in AOPs. It was shown in the radical quenching and electron paramagnetic resonance (EPR) experiments that both the radical and non-radical pathways were accountable for the degradation of contaminants, and the non-radical path was principal. It was also evident in the X-ray photoelectron spectroscopy (XPS) and density functional theory (DFT) results that pyridinic N and graphitic N were the main active species for PMS activation.
研究领域:
环境科学
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催化
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水处理
·
材料科学
✓ 已验证
DOI
高影响因子
BIOMEDICINE & PHARMACOTHERAPY
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2024
·
IF 6.9
Yuwei Yang,Yuanfang Chen,Haikang Tang,Ziqi Zhang,Xiaoliang Zhou,Wenqing Xu
Conventional antineoplastic therapies cause severe normal tissue damage and existing cytoprotectants with acute toxicities or potential tumor protection limit their clinical application. We evaluated the selective cytoprotection of 2,2-dimethylthiazolidine hydrochloride in this study, which could protect normal tissue toxicity without interfering antineoplastic therapies. By using diverse cell lines and A549 xenograft model, we discovered a synthetic aminothiol 2,2-dimethylthiazolidine hydrochloride selectively diminished normal cellular ferroptosis via SystemXc-/Glutathione Peroxidase 4 pathway upon antineoplastic therapies without interfering the anticancer efficacy. We revealed the malignant and non-malignant tissues presenting different energy metabolism patterns. And cisplatin induces disparate replicative stress, contributing to the distinguishable cytoprotection of 2,2-dimethylthiazolidine in normal and tumor cells. The compound pre-application could mitigate cisplatin-induced normal cellular mitochondrial oxidative phosphorylation (OXPHOS) dysfunction. Pharmacologic ablation of mitochondria reversed 2,2-dimethylthiazolidine chemoprotection against cisplatin in the normal cell line. Combined, these results provide a potential therapeutic adjuvant to selectively diminish normal tissue damages retaining antineoplastic efficacy.
研究领域:
肿瘤学
·
药理学
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细胞生物学
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分子生物学
✓ 已验证
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Xue-Feng Ma,Xue-Feng Yao,Zhi-Zhen Chi,Ming-Qiang Zhu
Eucommia ulmoides rubber (EUR) is a high-quality natural rubber resource, which can be extracted from different organs of the Eucommia ulmoides tree . In this study, EUR was isolated from the leaves, barks, and pericarps , and the structural characteristics and physicochemical properties of EUR were systematically determined. The accumulation and distribution of EUR in different tissues were assessed through in situ observations combined with cellular and subcellular scales. The preliminary analyses indicated that the variations in the physicochemical properties of EUR across different tissues were associated with its accumulation microstructure. Further analyses by SEM and TEM showed that the initial cell differentiation and fusion resulted in the formation of tubular structures without any nucleus. A limited number of rubber particles were generated within the cytoplasm, concurrent with aggregation and fusion. Eventually, rubber particles filled the entire cytoplasm, and organelles disappeared to form highly aggregated filamentous structures. In addition, the number and area of EUR-containing cells were closely related to the organization sizes of barks and leaves. This study provided valuable insights into Eucommia ulmoides histology and the rubber industry.
研究领域:
植物学
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材料科学
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植物生理学
✓ 已验证
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
·
2024
·
IF 4.3
Alimujiang Yalikun,Yanhong Wang,Yun Lv,Yaling Dou,Hyun-Joo Koo,Jiaojiao Cao,Wei Qi,Keke Huang,Myung-Hwan Whangbo,Zhongwen Ouyang,Hongcheng Lu
A series of analogous chain selenite chlorides Ba2M(SeO3)2Cl2 (M = Cu 1, Ni 2, Co 3, Mn 4) and Pb2Cu(SeO3)2Cl2 5 with tunable spin S from S = 1/2 to S = 5/2 have been hydrothermally synthesized and characterized. These analogues crystallized in the orthorhombic Pnnm space group (monoclinic P21/n space group for 5) all containing M2+–SeO3–M2+ spin chains, which are further separated by the Ba2+ ions (Pb2+ for 5). The magnetic susceptibility results of 1, 2, and 5 show broad maxima around 80.0, 18.9, and 78.0 K, respectively, indicating good one-dimensional (1D) magnetism. Meanwhile, no long-range order (LRO) is observed down to 2 K for both 1 and 5, while the isostructural compounds 2, 3, and 4 exhibit LRO at 3.4 K, 10.8 K, and 5.7 K, respectively, which are further confirmed by the heat capacity and electron spin resonance results, as well as the observed spin-flop transitions in the M–H curves measured at 2 K below TN. The magnetizations of 1–5 at 7 T are still far from saturation. In addition, thermal stability and FT-IR and UV–vis–NIR spectroscopy of 1–5 are reported.
研究领域:
无机化学
·
材料科学
·
固体物理
·
磁学
·
晶体学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）