JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2022
·Vol. 169
·期 6
·062504
·
IF 4.386
Fangzhao Pang,Peng Li,Zhuqing Zhao,Lei Guo,Kaifa Du,Bowen Deng,Dihua Wang,Huayi Yin
Electrolysis of solid oxides in molten CaCl2 has been proven a straightforward process to extract various metals thanks to the wide electrochemical window of CaCl2 and CaO which is soluble in molten CaCl2. However, the CaO produced during the cathodic reduction of oxides not only shuttles O2−, but also captures CO2 to generate CO32− that can be reduced to carbon at the cathode, resulting in decreasing current efficiency and contaminating the cathodic products by carbon. To solve this problem, we employed CaSiO3 to replace CaO to suppress/avoid the formation of CO32− and thereafter prevent the carbon deposition. The suppression of CO32− formation is because SiO32− is thermodynamically more stable than CO32−, i.e., the CO2 generated on the graphite anode can not be captured by SiO32−. In molten CaCl2−8.0 wt% CaSiO3, Cr2O3 and SiO2 are reduced to Cr and Si with much less carbon deposition than in molten CaCl2. As a result, the current efficiency increases from 21.4% to 51.9% for the reduction of Cr2O3 and 37.1% to 72.2% for the reduction of SiO2. Although introducing SiO32− will slightly decrease the electrochemical window of CaCl2, it will be a promising method to avoid carbon contamination and increase current efficiency especially for Si production.
研究领域:
材料科学
·
冶金工程
✓ 已验证
DOI
高影响因子
CRYSTAL GROWTH & DESIGN
·
2021
·
IF 4.076
Yunping Zhoujin,Xing Yang,Mingtao Zhang,Ju Guo,Sean Parkin,Tonglei Li,Faquan Yu,Sihui Long
A lactam–lactam dimer (LLD) and lactam NH···O═C (amide) catemer (LAC) are two competing motifs in N-phenyl-2-hydroxynicotinanilides (PHNAs). Steric effects play an important role in determining the outcome of this competition, and in general, PHNAs with no or negligible steric hindrance take on a near-planar conformation and form LLDs, rather than the widely observed amide NH···O═C hydrogen-bond chains. Conversely, those with significant steric hindrance are forced to take on a twisted conformation and form a lactam NH···O═C (amide) hydrogen bond. Nevertheless, steric factors are not the only criteria, as an LLD and an LAC have been observed in the two polymorphs (1-I and 1-II) of 2-hydroxy-N-m-tolyl-nicotinamide (namely 2-oxo-1,2-dihydropyridine-3-carboxylic acid m-tolylamide, compound 1), although the molecules in both forms have a nearly identical conformation, in contrast to five other newly synthesized PHNAs (2–6), whose crystal structures are sustained on the LLD. Thus, synthon polymorphism is possible in conformationally planar PHNAs. Theoretical studies were performed to provide an explanation for this observation. The lattice energies of the two forms of 1 showed only an insignificant difference. A Hirshfeld analysis revealed that the loss of stability due to less hydrogen bonding in 1-II is compensated by the participation of π–π stacking. Other than the commonly observed LLD in the crystals, π–π stacking provides a significant stabilization for each crystal, with its particular effects being dependent on the substitution pattern of the compound. A noncovalent interaction (NCI) analysis further provided a visual demonstration of the important intermolecular interactions. Potentially the other planar compounds could behave in a similar manner.
研究领域:
晶体学
·
理论化学
·
材料科学
✓ 已验证
DOI
高影响因子
JOURNAL OF ORGANIC CHEMISTRY
·
2023
·
IF 3.6
Qi Dang,Jiani Chen,Tianbao Li,Long Liu,Tianzeng Huang,Chunya Li,Tieqiao Chen
A palladium-catalyzed decarbonylative annulation of 2-arylbenzoic acids with internal alkynes via C(sp2)–H activation has been developed. A series of phenanthrenes were produced in moderate to good yield with good functional group tolerance. The mechanism study indicated that the C(sp2)–H activation should be the rate-determining step during the reaction.
研究领域:
有机化学
·
催化化学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2014
·Vol. 161
·期 10
·B201
·
IF 2.859
Yang Fan,Zijuan Yang,Xinhua Cao,Peifang Liu,Sen Chen,Zhen Cao
Hierarchical macro-mesoporous Ni(OH)2 were prepared by hydrothermal treatment of Ni(NO3)2 with dicyandiamide. This Ni(OH)2 nanostructure can be transformed to mesoporous NiO via calcination at 300°C. The structure, morphology and textural properties of the as-synthesized Ni(OH)2 and NiO were characterized. The electrochemical property and electrochemical sensing performance toward glucose detection were investigated. Owing to the unique macro-mesoporous structure, the Ni(OH)2 nanostructure could provide amperometric sensing of glucose with wide linear range (0.01–8.3 mM), high sensitivity of 243 μA mM cm−2 and low detection limit of 1 μM. Moreover, this glucose sensor also exhibited excellent stability, good selectivity and reproducibility.
研究领域:
材料科学
·
分析化学
✓ 已验证
DOI
高影响因子
ACS Applied Nano Materials
·
2022
·
IF 6.14
Binglin Guo,Yihao Gao,Yongyue Li,Xin Sun,Shuailin Chen,Meicheng Li
Ni(OH)2 has low production cost and high theoretical specific capacity, while on account of the poor electronic conductivity, it shows inferior electrochemical performance including cycling stability and rate capability. This work focuses on a composite material that is in situ grown Ni(OH)2 nanosheets on reduced graphene oxide (rGO), and employing the fewer-defect rGO to build a three-dimensional conductive network provides outstanding conductivity. The specific capacitances (Cm) of the Ni(OH)2/rGO (NHG) electrode are 2776 F·g–1 at 2 A·g–1 and even 1570 F·g–1 at 50 A·g–1, demonstrating remarkable rate capability. It indicates that the combination of the nano grown Ni(OH)2 and rGO conductive substrate shortens the ion diffusion path and increases the electron transfer rate; hence, the composite rate capability has been significantly improved. The composite materials and active carbon were combined to be an asymmetric supercapacitor, which had a high energy density of 39.24 Wh·kg–1 at 1962 W·kg–1. After 10,000 cycles at 5 A·g–1, the capacity retains 91.4%.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY
·
2018
·Vol. 95
·期 1
·79-88
·
IF 1.601
Ting Zheng,Zhenyu Wu,Qinglong Xie,Meizhen Lu,Fan Xia,Guangquan Wang,Yong Nie,Jianbing Ji
Owing to the decrease of global oil price, development of downstream value-added products is important to biodiesel industry. In this study, we used palmitic acid methyl ester (PAME) as a starting material to produce 2-ethylhexyl palmitate (2-EHP), an environmentally friendly biolubricant product, which was derived from the transesterification of fatty acid methyl esters and long chain fatty alcohols. Conventional synthetic routes of 2-EHP have disadvantages, including high catalyst price, low conversion efficiency, and pollution issues. To solve these problems, in situ transesterification of PAME with 2-ethylhexanol (2-EH) was conducted over unsupported potassium carbonate as heterogeneous catalyst. The optimal reaction temperature, 2-EH to PAME molar ratio, and catalyst to PAME mass ratio were 180 °C, 3:1, and 3.0 wt%, respectively. The PAME conversion reached up to 100% within 1 hour under the optimal conditions. In addition, a kinetic model describing the experimental data over a temperature range of 160–180 °C was developed. The dependence of kinetic rate constant ( k ) on temperature was evaluated, and the activation energy ( E a ) for the transesterification of PAME with 2-EH was calculated to be 57.04 kJ mol −1 .
研究领域:
化学工程
·
环境科学
✓ 已验证
DOI
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2025
·
IF 3.7
Mengtian Lu,Tianye Zhang,Yue Yang,Xin Lin,Jin Huang,Yuan Sun,Tiedong Sun
Graphical The study innovatively combines etched/stripped monolayer Ti 3 C 2 MXene with Cu (2- x ) Se nanoparticles in a one-pot method. The synthesized Ti 3 C 2 /Cu (2- x ) Se nanocomposite has catalase (CAT) and peroxidase (POD) -like activities combined with the excellent photothermal properties of MXene, which enhances the catalytic performance of Cu (2- x ) Se under near infrared (NIR) irradiation, and realizes the synergic photothermal catalytic treatment. Traditional tumor treatments (surgery, radiotherapy, chemotherapy, etc.) have certain limitations and can have serious negative effects, such as difficulty in cutting out tumors, damage to normal tissues, and complications. Ordinary nanozymes have low catalytic activity and require higher doses for treatment, which can increase in vivo toxicity and side effects. To address these limitations, we developed a Ti 3 C 2 MXene-based nanocomposite (Ti 3 C 2 /Cu (2- x ) Se) integrating Cu (2- x ) Se nanozymes with dual enzyme-mimicking activities (catalase and peroxidase) and MXene's photothermal properties. The Cu (2- x ) Se component catalyzes the decomposition of tumor-overexpressed H 2 O 2 into O 2 and cytotoxic ·OH, alleviating hypoxia while inducing oxidative stress. Simultaneously, MXene's high surface area and photothermal capability enhance nanozyme stability, biocompatibility, and catalytic efficiency under near-infrared irradiation. Notably, the photothermal effect amplifies enzymatic activity, enabling synergistic nanocatalytic-photothermal therapy. This synergy not only degrades glutathione to suppress tumor antioxidant defenses but also achieves targeted tumor ablation with reduced dosage requirements. Our work highlights a rational design of MXene-based nanozymes for enhanced multimodal tumor therapy, offering a paradigm for nanocomposite-driven disease treatment.
研究领域:
生物医学工程
·
纳米医学
·
肿瘤学
✓ 已验证
DOI
PubMed
高影响因子
STAR Protocols
·
2022
·
IF 0
Qianqian Fang,Zhengkang Hua,Zhonghui Lin
Summary The human MUS81-EME1&2 complexes are structure-selective endonucleases that play important roles in DNA damage repair. Here, we describe a protocol to determine the endonuclease activities of MUS81-EME1&2 complexes toward various DNA structures. We co-express MUS81 with EME1 or EME2 and purify the complexes with high purity, and determine their activities on the cleavages of 3ˊ flaps, 5ˊ flaps, nicked double-stranded DNAs, and Holliday junctions. This protocol can also be used for the determination of substrate preferences of other structure-selective endonucleases. For complete details on the use and execution of this protocol, please refer to Hua et al. (2022) .
研究领域:
分子生物学
·
细胞生物学
·
遗传学
✓ 已验证
DOI
PubMed
Journal of the Australian Ceramic Society
·
2019
·Vol. 56
·期 2
·795-801
·
IF 0.692
Zhang Tao,Wei Yaowu,Chen Junfeng,Li Nan
In spite of the advantages of CaO refractories, such as high refractoriness, potential to produce pure steel molten, and high alkaline corrosion resistance, their application has been limited due to its poor hydration resistance. Introducing additives to improve the hydration resistance of lime is a novel method. The influences of Mg(OH) 2 and sintering temperatures on the sintering and hydration resistance of CaO aggregates that were produced by thermal decomposition were investigated in this paper. The purpose of this work was to produce high-purity CaO raw material with high density, low porosity, well grain growth, and good hydration resistance economically. The sintered samples were characterized by bulk density, apparent porosity, surface appearance, and microstructure. The results indicated that (1) Mg(OH) 2 promoted the grain growth of CaO, reduced the apparent porosity, and improved the density of the specimens. The hydration resistance of the samples was increased. (2) Increasing the sintering temperature improved the hydration resistance of the specimens obviously in the experiment. (3) Grain size of CaO was more uniform with the increment of Mg(OH) 2 content, and the density of the compacts was improved.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
INFRARED PHYSICS & TECHNOLOGY
·
2025
·
IF 3.4
Ping Wang,Bin Duan,Yuanyuan Fan,Min Luo,Liming Tang,Changchun Ding,Tong Liu,Wei Jin,Junshan Hu
A novel upconversion phosphor, Ca 3 (VO 4 ) 2 co-doped with Yb 3+ and Er 3+ , was successfully synthesized via a high-temperature solid-state method. Under 980 nm near-infrared excitation, this material exhibits remarkable upconversion luminescence, with intense green emissions at 527 nm and 550 nm, and a weaker red emission at 657 nm. The optimal doping concentrations were determined to be 0.03 for Yb 3+ and 0.005 for Er 3+ , enabling maximum luminescent efficiency. Spectroscopic investigations including upconversion photoluminescence, excitation, and emission spectra confirmed that the upconversion follows a distinct energy transfer mechanism: Yb 3+ ( 2 F 5/2 ) + Er 3+ ( 4 I 11/2 ) → Yb 3+ ( 2 F 7/2 ) + Er 3+ ( 4 F 7/2 ). In addition to its excellent luminescent properties, the Ca 3 (VO 4 ) 2 : 0.03Yb 3+ /0.005Er 3+ phosphor exhibits reliable optical thermal sensitivity over a wide temperature range (298–673 K), with a peak relative sensitivity of 1.11 % K −1 at 298 K. These outstanding optical characteristics make Ca 3 (VO 4 ) 2 : 0.03Yb 3+ /0.005Er 3+ a promising candidate for display and lighting technologies.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Biomedical Nanotechnology
·
2022
·Vol. 18
·期 11
·2470-2478
·
IF 3.641
Tu Rong,You Xiaoguang,Ding Zhichao,Wu Huanyu,Zhao Linlu,Qiu Zhi,Wei Junjie,Yang Xiaofeng
Development of imaging methods that can detect target molecules will be of great significance for non-invasive molecular diagnosis. Vascular endothelial growth factor receptor-2 (VEGFR-2) is a broadly expressed target, and VEGFR-2-specific agents have been used in biological therapy.
In this study, amine-reactive coupling was used to label the polypeptide VEGF125–136 with a Gd(DOTA) complex to create a magnetic resonance contrast agent, VEGF125–136-Gd, which binds to VEGFR-2. Using T1-weighted magnetic resonance imaging, we explored the tumor cell-targeting
ability of VEGF125–136-Gd and its enhancement of T1-weighted image intensity using human hepatoma (HepG2) cells and found that the signal-to-noise ratio (SNR) increased commensurately with the concentration of VEGF125–136-Gd. At a concentration of 2 mM, the SNR produced by VEGF125–136-Gd
was 5.4-fold higher than that produced by a Gd-labelled non-targeting polypeptide (NTPP-Gd) control. We also evaluated the tumor-targeting efficiency of VEGF125–136-Gd in nude mice injected with human hepatoma (HepG2) cells. Preliminary in vivo imaging of VEGFR-2 in tumor tissue
revealed a targeting peak 60 min post administration of VEGF125–136-Gd, the intensity of which was 23% higher than the SNR of NTPP-Gd at the same time point. Our findings may help lay the foundation for clinical applications of VEGF125–136-Gd in targeted imaging.
研究领域:
医学影像
·
癌症生物学
·
分子生物学
·
药学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2022
·Vol. 12
·期 21
·13251-13260
·
IF 4.036
Xinglong Li,Mingming Li,Yuxin Liu,Yisi Feng,Pan Pan
5-Hydroxymethylfurfural (HMF) is one of the most important platform molecules and could be transformed into a variety of fuel additives and high value-added chemicals. Multiple catalyst systems have been developed for the conversion of carbohydrates to HMF, but there are still unavoidable problems, including high temperature and pressure, difficult recovery of solvent, corrosion of equipment, poor catalyst circulation, etc. Herein, a new magnetic Fe3O4@SiO2@mSiO2-TaOPO4 catalyst for the preparation of HMF from fructose in 2-pentanol was developed. The structures of the catalysts were characterized by FT-IR, TSM, EDS, SEM, XRD and VSM. The 2-pentanol solvent is not only conducive to the production of HMF, but also enables the reaction to be carried out at a lower pressure. The highest yield of HMF (85.4%) was obtained using 20 wt% catalyst under 10% substrate concentration (0.5 g of fructose) at 120 °C for 3 h. The catalysts can be easily separated by magnetism. The slight decrease in catalyst activity after 7 cycles was mainly due to the loss of catalyst during the cycle operation. Simultaneously, the total yield of HMF was 51.3% after scale-up to 15 g of fructose, showing the possible industrial application potential of this catalyst system.
研究领域:
化学工程
·
催化材料
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）